STRINGSTRING
AFUA_3G14445 AFUA_3G14445 AFUA_3G10070 AFUA_3G10070 AFUA_5G07270 AFUA_5G07270 AFUA_5G07265 AFUA_5G07265 sin4 sin4 AFUA_5G04333 AFUA_5G04333 AFUA_5G03485 AFUA_5G03485 srb4 srb4 AFUA_4G04360 AFUA_4G04360 AFUA_4G03810 AFUA_4G03810 AFUA_4G03430 AFUA_4G03430 AFUA_7G01850 AFUA_7G01850 AFUA_7G01920 AFUA_7G01920 AFUA_7G02080 AFUA_7G02080 AFUA_7G02620 AFUA_7G02620 fumR fumR AFUA_8G05490 AFUA_8G05490 AFUA_8G05300 AFUA_8G05300 AFUA_8G05290 AFUA_8G05290 AFUA_8G04950 AFUA_8G04950 AFUA_8G04350 AFUA_8G04350 AFUA_6G02210 AFUA_6G02210 AFUA_6G04400 AFUA_6G04400 AFUA_6G04580 AFUA_6G04580 AFUA_6G04610 AFUA_6G04610 med6 med6 AFUA_5G03160 AFUA_5G03160 AFUA_5G03320 AFUA_5G03320 AFUA_5G03660 AFUA_5G03660 AFUA_5G03680 AFUA_5G03680 rpc82 rpc82 AFUA_3G04230 AFUA_3G04230 AFUA_3G03530 AFUA_3G03530 AFUA_3G02940 AFUA_3G02940 AFUA_3G02870 AFUA_3G02870 AFUA_7G03670 AFUA_7G03670 AFUA_7G03720 AFUA_7G03720 AFUA_7G03860 AFUA_7G03860 AFUA_7G05000 AFUA_7G05000 pob3 pob3 AFUA_7G08250 AFUA_7G08250 rgr1 rgr1 AFUA_2G05480 AFUA_2G05480 AFUA_2G04790 AFUA_2G04790 AFUA_2G01900 AFUA_2G01900 AFUA_2G01550 AFUA_2G01550 AFUA_2G00980 AFUA_2G00980 AFUA_2G00870 AFUA_2G00870 spt16 spt16 AFUA_1G07020 AFUA_1G07020 AFUA_1G06380 AFUA_1G06380 AFUA_1G06060 AFUA_1G06060 nut2 nut2 AFUA_1G05160 AFUA_1G05160 AFUA_1G03070 AFUA_1G03070 AFUA_1G02590 AFUA_1G02590 AFUA_1G02460 AFUA_1G02460 AFUA_1G00120 AFUA_1G00120 MED4 MED4 AFUA_6G13740 AFUA_6G13740 AFUA_6G13130 AFUA_6G13130 AFUA_6G10530 AFUA_6G10530 med7 med7 AFUA_6G08600 AFUA_6G08600 AFUA_6G08300 AFUA_6G08300 srb5 srb5 nut1 nut1 med8 med8 spt5 spt5 AFUA_4G08900 AFUA_4G08900 AFUA_4G09920 AFUA_4G09920 MED20 MED20 AFUA_4G11690 AFUA_4G11690 AFUA_4G11970 AFUA_4G11970 AFUA_4G12400 AFUA_4G12400 MED19 MED19 AFUA_4G13130 AFUA_4G13130 AFUA_1G17400 AFUA_1G17400 AFUA_1G14740 AFUA_1G14740 AFUA_1G14680 AFUA_1G14680 AFUA_1G14110 AFUA_1G14110 AFUA_1G13990 AFUA_1G13990 AFUA_1G13910 AFUA_1G13910 AFUA_1G13900 AFUA_1G13900 iws1 iws1 AFUA_1G11850 AFUA_1G11850 AFUA_1G10040 AFUA_1G10040 AFUA_1G09350 AFUA_1G09350 AFUA_1G09180 AFUA_1G09180 bur1 bur1 AFUA_5G05870 AFUA_5G05870 AFUA_5G06280 AFUA_5G06280 spt4 spt4 AFUA_5G07030 AFUA_5G07030 AFUA_5G11120 AFUA_5G11120 AFUA_5G11460 AFUA_5G11460 AFUA_5G11580 AFUA_5G11580 AFUA_5G14850 AFUA_5G14850 chl1 chl1 spt6 spt6 AFUA_3G06090 AFUA_3G06090 srb8 srb8 AFUA_3G07670 AFUA_3G07670 AFUA_3G08040 AFUA_3G08040 MED9 MED9 AFUA_3G10120 AFUA_3G10120 AFUA_3G10620 AFUA_3G10620 AFUA_3G11410 AFUA_3G11410 AFUA_3G11810 AFUA_3G11810 AFUA_3G12730 AFUA_3G12730 AFUA_3G13410 AFUA_3G13410 ssn3 ssn3 soh1 soh1 AFUA_3G14370 AFUA_3G14370 tfb5 tfb5 AFUA_2G17100 AFUA_2G17100 AFUA_2G16170 AFUA_2G16170 ssn8 ssn8 AFUA_2G15680 AFUA_2G15680 AFUA_2G15670 AFUA_2G15670 AFUA_2G15600 AFUA_2G15600 AFUA_2G14890 AFUA_2G14890 AFUA_2G14880 AFUA_2G14880 AFUA_2G13720 AFUA_2G13720 srb7 srb7 AFUA_2G13090 AFUA_2G13090 AFUA_2G12600 AFUA_2G12600 AFUA_2G12130 AFUA_2G12130 AFUA_2G11770 AFUA_2G11770 AFUA_2G11190 AFUA_2G11190 AFUA_2G11000 AFUA_2G11000 AFUA_2G10310 AFUA_2G10310 AFUA_2G08880 AFUA_2G08880 AFUA_2G08540 AFUA_2G08540 AFUA_2G08450 AFUA_2G08450 AFUA_2G08170 AFUA_2G08170
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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AFUA_3G14445Bromodomain associated domain protein. (349 aa)
AFUA_3G10070Cyclin, putative; Belongs to the cyclin family. (559 aa)
AFUA_5G07270DNA-directed RNA polymerase III subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. (253 aa)
AFUA_5G07265Uncharacterized protein. (651 aa)
sin4Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (955 aa)
AFUA_5G04333General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (456 aa)
AFUA_5G03485Uncharacterized protein. (268 aa)
srb4Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (639 aa)
AFUA_4G04360RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (479 aa)
AFUA_4G03810Uncharacterized protein. (346 aa)
AFUA_4G03430C6 transcription factor, putative. (641 aa)
AFUA_7G01850DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. (352 aa)
AFUA_7G01920DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1255 aa)
AFUA_7G02080RNA polymerase I subunit Rpa43, putative. (428 aa)
AFUA_7G02620DNA-directed RNA polymerases N/8 kDa subunit superfamily. (140 aa)
fumRC6 finger transcription factor fumR; Transcription factor that regulates the expression of the gene clusters that mediate the biosynthesis of pseurotin and fumagillin. (622 aa)
AFUA_8G05490Transcription initiation factor iif, beta subunit. (374 aa)
AFUA_8G05300RNA polymerase II subunit 7. (139 aa)
AFUA_8G05290Uncharacterized protein. (477 aa)
AFUA_8G04950Transcription initiation factor TFIID subunit TSM1/127kD, putative. (1358 aa)
AFUA_8G04350DNA-directed RNA polymerase III subunit 22.9 kDa, putative. (112 aa)
AFUA_6G02210Cytochrome P450 monooxygenase, putative; Belongs to the cytochrome P450 family. (533 aa)
AFUA_6G04400Transcription factor TFIIIB component, putative. (586 aa)
AFUA_6G04580NIF domain protein. (625 aa)
AFUA_6G04610DNA-directed RNA polymerase I and III 14 kDa polypeptide. (161 aa)
med6Mediator of RNA polymerase II transcription subunit 6; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (324 aa)
AFUA_5G03160Protein kinase, putative. (1092 aa)
AFUA_5G03320TFIIH complex helicase Ssl2, putative. (830 aa)
AFUA_5G03660Transcription initiation factor TFIID subunit beta, putative. (401 aa)
AFUA_5G03680Transcription initiation factor TFIID complex 60 kDa subunit. (445 aa)
rpc82DNA-directed RNA polymerase III subunit rpc3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs (By similarity). (629 aa)
AFUA_3G04230Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (667 aa)
AFUA_3G03530Nitroreductase family protein. (196 aa)
AFUA_3G02940Allergen, putative. (264 aa)
AFUA_3G02870NUDIX domain, putative. (178 aa)
AFUA_7G03670Uncharacterized protein. (532 aa)
AFUA_7G03720Serine/threonine protein kinase (Kin28), putative; Belongs to the protein kinase superfamily. (404 aa)
AFUA_7G03860DNA-directed RNA polymerase II subunit RPB11a, putative. (167 aa)
AFUA_7G05000Uncharacterized protein. (489 aa)
pob3FACT complex subunit pob3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (573 aa)
AFUA_7G08250C6 finger domain protein, putative. (1087 aa)
rgr1Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (1093 aa)
AFUA_2G05480DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (121 aa)
AFUA_2G04790Mediator of RNA polymerase II transcription subunit 13; Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex. (1429 aa)
AFUA_2G01900RNA polymerase II transcription elongation factor Rtf1p, putative. (607 aa)
AFUA_2G01550Repressor of RNA polymerase III transcription MAF1; Mediator of diverse signals that repress RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA. Belongs to the MAF1 family. (335 aa)
AFUA_2G00980Uncharacterized protein. (199 aa)
AFUA_2G00870Uncharacterized protein. (430 aa)
spt16FACT complex subunit spt16; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (1019 aa)
AFUA_1G07020Cyclin, putative; Belongs to the cyclin family. (438 aa)
AFUA_1G06380DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (116 aa)
AFUA_1G06060Uncharacterized protein. (1502 aa)
nut2Mediator of RNA polymerase II transcription subunit 10; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (159 aa)
AFUA_1G05160DNA-directed RNA polymerase I, II, and III subunit Rpb6. (161 aa)
AFUA_1G03070Transcription initiation factor TFIID subunit, putative. (745 aa)
AFUA_1G02590RNA polymerase I specific transcription initiation factor RRN3 superfamily. (713 aa)
AFUA_1G02460DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1200 aa)
AFUA_1G00120Uncharacterized protein. (171 aa)
MED4Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (328 aa)
AFUA_6G13740Uncharacterized protein. (302 aa)
AFUA_6G13130Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (290 aa)
AFUA_6G10530Transcriptional elongation regulator Elc1/Elongin C, putative; Belongs to the SKP1 family. (104 aa)
med7Mediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (261 aa)
AFUA_6G08600Transcription factor TFIID complex 145 kDa subunit, putative. (1093 aa)
AFUA_6G08300DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1235 aa)
srb5Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (268 aa)
nut1Mediator of RNA polymerase II transcription subunit 5; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (1007 aa)
med8Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (249 aa)
spt5Transcription elongation factor spt5; The spt4-spt5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene (By similarity). (1058 aa)
AFUA_4G08900CDK-activating kinase assembly factor MAT1. (379 aa)
AFUA_4G09920Nitroreductase domain-containing protein. (284 aa)
MED20Mediator of RNA polymerase II transcription subunit 20; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (286 aa)
AFUA_4G11690RNA polymerase II transcription factor related protein. (642 aa)
AFUA_4G11970Metallothionein-I gene transcription activator. (76 aa)
AFUA_4G12400PHD finger domain protein, putative. (836 aa)
MED19Mediator of RNA polymerase II transcription subunit 19; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (460 aa)
AFUA_4G13130Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (769 aa)
AFUA_1G17400Peptidase S41 family protein. (648 aa)
AFUA_1G14740Transcription factor TFIIA complex subunit Toa1, putative. (392 aa)
AFUA_1G14680DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1750 aa)
AFUA_1G14110RNA polymerase subunit. (171 aa)
AFUA_1G13990Uncharacterized protein. (285 aa)
AFUA_1G13910TFIIH complex helicase Rad3, putative. (770 aa)
AFUA_1G13900DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1680 aa)
iws1Transcription factor iws1; Transcription factor involved in RNA polymerase II transcription regulation. May function in both SPT15/TBP post- recruitment and recruitment steps of transcription (By similarity). Belongs to the IWS1 family. (460 aa)
AFUA_1G11850DUF4211 domain-containing protein. (580 aa)
AFUA_1G10040HMG box protein, putative. (399 aa)
AFUA_1G09350Transcription initiation factor TFIID subunit 13, putative. (298 aa)
AFUA_1G09180Uncharacterized protein. (470 aa)
bur1Serine/threonine-protein kinase bur1; Serine/threonine-protein kinase involved in transcription regulation. Phosphorylates the UBC2/RAD6 ubiquitin-conjugating enzyme (E2), leading to monoubiquitination of histone H2B and the silencing of telomeric-associated genes. Also required for histone H3 methylation. Necessary for the recovery from pheromone-induced growth arrest in the cell cycle G1 phase (By similarity). (580 aa)
AFUA_5G05870RNA polymerase II transcription elongation factor (Ctr9), putative. (1195 aa)
AFUA_5G06280Uncharacterized protein. (508 aa)
spt4Transcription elongation factor spt4; The spt4-spt5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene (By similarity). (156 aa)
AFUA_5G07030Cyclin Ccl1, putative; Belongs to the cyclin family. (433 aa)
AFUA_5G11120DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (145 aa)
AFUA_5G11460Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...] (284 aa)
AFUA_5G11580Transcription factor TFIIH subunit Tfb4, putative. (387 aa)
AFUA_5G14850Uncharacterized protein. (267 aa)
chl1ATP-dependent DNA helicase chl1; ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (By similarity). May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (By similarity). Has a specific role in chromosome segregation during meiosis II (By similarity). (782 aa)
spt6Transcription elongation factor spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression (By similarity); Belongs to the SPT6 family. (1420 aa)
AFUA_3G06090Transcription initiation factor TFIID subunit 12, putative. (614 aa)
srb8Mediator of RNA polymerase II transcription subunit 12; Component of the srb8-11 complex. The srb8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The srb8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex (By similarity). (1617 aa)
AFUA_3G07670Transcription elongation factor S-II. (304 aa)
AFUA_3G08040Polymerase (RNA) II (DNA directed) polypeptide D. (148 aa)
MED9Mediator of RNA polymerase II transcription subunit 9; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (167 aa)
AFUA_3G10120RNA polymerase I and III transcription factor complex component Tbp, putative. (283 aa)
AFUA_3G10620Transcription initiation protein. (422 aa)
AFUA_3G11410RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (827 aa)
AFUA_3G11810Uncharacterized protein. (605 aa)
AFUA_3G12730Transcription factor TFIIIB complex subunit Brf1, putative. (748 aa)
AFUA_3G13410Uncharacterized protein. (229 aa)
ssn3Serine/threonine-protein kinase ssn3; Component of the srb8-11 complex. The srb8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The srb8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex. The srb8-11 complex phosphorylates the C-terminal domain (CTD) of the largest subunit of RNA polymerase II (By similarity). (426 aa)
soh1Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (162 aa)
AFUA_3G14370DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1453 aa)
tfb5General transcription and DNA repair factor IIH subunit tfb5; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has be [...] (72 aa)
AFUA_2G17100Uncharacterized protein. (316 aa)
AFUA_2G16170DNA-directed RNA polymerase III RPC4, putative. (606 aa)
ssn8RNA polymerase II holoenzyme cyclin-like subunit; Component of the srb8-11 complex. The srb8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The srb8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex. The srb8-11 complex phosphorylates the C-terminal domain (CTD) of the largest subunit of RNA polymerase II (By s [...] (302 aa)
AFUA_2G15680Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (111 aa)
AFUA_2G15670Uncharacterized protein. (289 aa)
AFUA_2G15600Uncharacterized protein. (315 aa)
AFUA_2G14890Bromodomain associated domain protein. (217 aa)
AFUA_2G14880Transcription initiation factor TFIID subunit 7, putative. (486 aa)
AFUA_2G13720DNA-directed RNA polymerase I and III subunit Rpc40, putative. (374 aa)
srb7Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (207 aa)
AFUA_2G13090RNA polymerase II subunit 3. (392 aa)
AFUA_2G12600Uncharacterized protein. (699 aa)
AFUA_2G12130CID domain-containing protein. (239 aa)
AFUA_2G11770SAP30_Sin3_bdg domain-containing protein. (228 aa)
AFUA_2G11190Pol II transcription elongation factor subunit Cdc73, putative. (471 aa)
AFUA_2G11000Uncharacterized protein. (562 aa)
AFUA_2G10310DUF408 domain protein. (326 aa)
AFUA_2G08880Uncharacterized protein. (128 aa)
AFUA_2G08540DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (128 aa)
AFUA_2G08450Transcription factor TFIIE complex alpha subunit, putative. (440 aa)
AFUA_2G08170RNA polymerase II transcription factor SIII (Elongin) subunit A, putative. (396 aa)
Your Current Organism:
Aspergillus fumigatus
NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293
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