(13 nodes) Rho (Ras homology) subfamily of Ras-like small GTPases, and CDC42 GTPase cycle network (Aspergillus fumigatus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AFUA_3G06690	Rho GTPase Rho3. (197 aa)
	AFUA_4G04120	Protein kinase activator Bem1, putative. (598 aa)
	AFUA_7G04600	Rho guanyl nucleotide exchange factor, putative. (1940 aa)
	AFUA_2G05740	Rho GTPase ModA, putative. (192 aa)
	AFUA_4G11450	Rho guanyl nucleotide exchange factor, putative. (907 aa)
	AFUA_1G12680	Rho GTPase activator Rga, putative. (1101 aa)
	AFUA_5G05900	Non-specific serine/threonine protein kinase. (836 aa)
	AFUA_5G11380	Rho-gdp dissociation inhibitor. (197 aa)
	AFUA_5G14060	Rho GTPase Rho4, putative. (286 aa)
	AFUA_3G06280	Rho GTPase activator (Rgd1), putative. (669 aa)
	AFUA_3G06300	Rho GTPase Rac, putative. (199 aa)
	AFUA_3G10340	Rho GTPase Rho 2, putative. (207 aa)
	AFUA_2G15050	Rho GTPase activator (Lrg11), putative. (1237 aa)

Your Current Organism:

Aspergillus fumigatus

NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFUA_1G12680	AFUA_2G05740	Q4WSI2	Q4WHE0	Rho GTPase activator Rga, putative.	Rho GTPase ModA, putative.	0.999
AFUA_1G12680	AFUA_2G15050	Q4WSI2	Q4X015	Rho GTPase activator Rga, putative.	Rho GTPase activator (Lrg11), putative.	0.855
AFUA_1G12680	AFUA_3G06280	Q4WSI2	Q4WWL3	Rho GTPase activator Rga, putative.	Rho GTPase activator (Rgd1), putative.	0.992
AFUA_1G12680	AFUA_3G06300	Q4WSI2	Q4WWL5	Rho GTPase activator Rga, putative.	Rho GTPase Rac, putative.	0.999
AFUA_1G12680	AFUA_3G06690	Q4WSI2	E9RB80	Rho GTPase activator Rga, putative.	Rho GTPase Rho3.	0.999
AFUA_1G12680	AFUA_3G10340	Q4WSI2	Q4WXQ6	Rho GTPase activator Rga, putative.	Rho GTPase Rho 2, putative.	0.999
AFUA_1G12680	AFUA_4G04120	Q4WSI2	Q4W9Q3	Rho GTPase activator Rga, putative.	Protein kinase activator Bem1, putative.	0.760
AFUA_1G12680	AFUA_4G11450	Q4WSI2	Q4WQ37	Rho GTPase activator Rga, putative.	Rho guanyl nucleotide exchange factor, putative.	0.965
AFUA_1G12680	AFUA_5G05900	Q4WSI2	Q4WTS2	Rho GTPase activator Rga, putative.	Non-specific serine/threonine protein kinase.	0.955
AFUA_1G12680	AFUA_5G11380	Q4WSI2	Q4WVA3	Rho GTPase activator Rga, putative.	Rho-gdp dissociation inhibitor.	0.611
AFUA_1G12680	AFUA_5G14060	Q4WSI2	Q4WW13	Rho GTPase activator Rga, putative.	Rho GTPase Rho4, putative.	0.999
AFUA_1G12680	AFUA_7G04600	Q4WSI2	Q4WGC9	Rho GTPase activator Rga, putative.	Rho guanyl nucleotide exchange factor, putative.	0.965
AFUA_2G05740	AFUA_1G12680	Q4WHE0	Q4WSI2	Rho GTPase ModA, putative.	Rho GTPase activator Rga, putative.	0.999
AFUA_2G05740	AFUA_2G15050	Q4WHE0	Q4X015	Rho GTPase ModA, putative.	Rho GTPase activator (Lrg11), putative.	0.938
AFUA_2G05740	AFUA_3G06280	Q4WHE0	Q4WWL3	Rho GTPase ModA, putative.	Rho GTPase activator (Rgd1), putative.	0.776
AFUA_2G05740	AFUA_3G06690	Q4WHE0	E9RB80	Rho GTPase ModA, putative.	Rho GTPase Rho3.	0.520
AFUA_2G05740	AFUA_3G10340	Q4WHE0	Q4WXQ6	Rho GTPase ModA, putative.	Rho GTPase Rho 2, putative.	0.528
AFUA_2G05740	AFUA_4G04120	Q4WHE0	Q4W9Q3	Rho GTPase ModA, putative.	Protein kinase activator Bem1, putative.	0.993
AFUA_2G05740	AFUA_4G11450	Q4WHE0	Q4WQ37	Rho GTPase ModA, putative.	Rho guanyl nucleotide exchange factor, putative.	0.994
AFUA_2G05740	AFUA_5G05900	Q4WHE0	Q4WTS2	Rho GTPase ModA, putative.	Non-specific serine/threonine protein kinase.	0.989