STRINGSTRING
AFUA_1G05410 AFUA_1G05410 AFUA_2G08860 AFUA_2G08860 AFUA_2G11380 AFUA_2G11380 AFUA_2G12890 AFUA_2G12890 AFUA_2G13130 AFUA_2G13130 AFUA_2G14950 AFUA_2G14950 AFUA_2G16040 AFUA_2G16040 esf2 esf2 nop58 nop58 nop9 nop9 AFUA_7G04430 AFUA_7G04430 dbp3 dbp3 AFUA_2G03740 AFUA_2G03740 rps21 rps21 AFUA_2G03340 AFUA_2G03340 AFUA_2G02340 AFUA_2G02340 grc3 grc3 AFUA_2G01330 AFUA_2G01330 mrd1 mrd1 AFUA_1G04240 AFUA_1G04240 AFUA_1G02680 AFUA_1G02680 AFUA_5G12860 AFUA_5G12860 AFUA_5G13530 AFUA_5G13530 AFUA_3G05860 AFUA_3G05860 AFUA_3G06380 AFUA_3G06380 AFUA_3G09880 AFUA_3G09880 AFUA_1G02210 AFUA_1G02210 AFUA_1G02200 AFUA_1G02200 pno1 pno1 AFUA_6G06380 AFUA_6G06380 AFUA_4G07500 AFUA_4G07500 ytm1 ytm1 nop7 nop7 AFUA_4G12200 AFUA_4G12200 AFUA_4G12250 AFUA_4G12250 erb1 erb1 AFUA_5G05930 AFUA_5G05930 TIF6 TIF6 AFUA_5G10840 AFUA_5G10840 AFUA_8G05430 AFUA_8G05430 AFUA_8G04640 AFUA_8G04640 AFUA_6G02160 AFUA_6G02160 AFUA_6G04260 AFUA_6G04260 rai1 rai1 AFUA_6G05270 AFUA_6G05270 spb1 spb1 AFUA_6G05310 AFUA_6G05310 AFUA_5G03090 AFUA_5G03090 AFUA_3G04110 AFUA_3G04110
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AFUA_1G05410Ribosome biogenesis protein Kri1. (617 aa)
AFUA_2G08860Exosome complex endonuclease 2/ribosomal RNA processing protein, putative. (292 aa)
AFUA_2G11380KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. (358 aa)
AFUA_2G12890Small nucleolar ribonucleoprotein complex subunit, putative. (535 aa)
AFUA_2G131303' exoribonuclease family protein (Rrp42), putative. (390 aa)
AFUA_2G14950Exonuclease, putative. (750 aa)
AFUA_2G16040rRNA biogenesis protein RRP5, putative. (1822 aa)
esf2Pre-rRNA-processing protein esf2; Involved in the small subunit (SSU) processome assembly and function, and in the 18S rRNA synthesis. Required for the early cleavages at sites A0, A1 and A2 (By similarity); Belongs to the ESF2/ABP1 family. (361 aa)
nop58Nucleolar protein 58; Required for pre-18S rRNA processing. May bind microtubules (By similarity); Belongs to the NOP5/NOP56 family. (591 aa)
nop9Nucleolar protein 9; RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit (By similarity); Belongs to the NOP9 family. (699 aa)
AFUA_7G04430Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (220 aa)
dbp3ATP-dependent RNA helicase dbp3; ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5.8S rRNAs (By similarity); Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily. (503 aa)
AFUA_2G03740Exosome complex endonuclease 1/ribosomal RNA processing protein, putative. (269 aa)
rps2140S ribosomal protein S21; Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Has a physiological role leading to 18S rRNA stability (By similarity). (88 aa)
AFUA_2G03340DUF652 domain protein. (192 aa)
AFUA_2G02340Exosome complex exonuclease Rrp40, putative. (274 aa)
grc3Polynucleotide 5'-hydroxyl-kinase grc3; Polynucleotide 5'-kinase involved in rRNA processing. Belongs to the Clp1 family. NOL9/GRC3 subfamily. (841 aa)
AFUA_2G01330Exosome complex subunit Rrp46, putative. (249 aa)
mrd1Multiple RNA-binding domain-containing protein 1; Involved in pre-rRNA processing; Belongs to the RRM MRD1 family. (825 aa)
AFUA_1G04240Small nucleolar ribonucleoprotein complex subunit Utp14, putatrive. (960 aa)
AFUA_1G02680Small nucleolar ribonucleoprotein complex subunit Dip2, putative. (1000 aa)
AFUA_5G12860Uncharacterized protein. (392 aa)
AFUA_5G13530Exosome complex subunit Csl4, putative. (249 aa)
AFUA_3G05860Exosome complex exonuclease Rrp4, putative. (390 aa)
AFUA_3G06380Exosome-associated family protein. (248 aa)
AFUA_3G09880Exosome complex exonuclease Rrp6, putative. (764 aa)
AFUA_1G0221060S ribosome biogenesis protein Brx1, putative. (376 aa)
AFUA_1G02200F-box domain protein. (357 aa)
pno1Pre-rRNA-processing protein pno1; Required for small ribosomal subunit (SSU) synthesis. Has a role in the processing of early nucleolar and late cytoplasmic pre-RNA species (By similarity). (252 aa)
AFUA_6G06380Methyltransferase, putative. (245 aa)
AFUA_4G07500Small nucleolar ribonucleoprotein complex subunit, putative. (656 aa)
ytm1Ribosome biogenesis protein ytm1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (488 aa)
nop7Pescadillo homolog; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (675 aa)
AFUA_4G12200Uncharacterized protein. (367 aa)
AFUA_4G12250Exosome complex exonuclease exoribonuclease (Rrp44), putative; Belongs to the RNR ribonuclease family. (1034 aa)
erb1Ribosome biogenesis protein erb1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (795 aa)
AFUA_5G05930RNA processing factor 1. (425 aa)
TIF6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family. (247 aa)
AFUA_5G10840Ribosome biogenesis protein Urb1, putative. (1124 aa)
AFUA_8G05430Ribosome biogenesis protein Noc4, putative. (569 aa)
AFUA_8G04640RNA-3'-phosphate cyclase family protein. (403 aa)
AFUA_6G021603' exoribonuclease family protein. (411 aa)
AFUA_6G04260Protein MAK16; Belongs to the MAK16 family. (324 aa)
rai1Decapping nuclease rai1; Ribonuclease that specifically degrades pre-mRNAs with a defective 5' end cap and is part of a pre-mRNA capping quality control. Has decapping and pyrophosphohydrolase activities. Has decapping activity toward incomplete 5' end cap mRNAs such as unmethylated 5' end-capped RNA to release GpppN and 5' end monophosphate RNA. Also possesses RNA 5'-pyrophosphohydrolase activity by hydrolyzing the 5' end triphosphate to release pyrophosphates (By similarity). Belongs to the DXO/Dom3Z family. (365 aa)
AFUA_6G05270Uncharacterized protein. (195 aa)
spb1AdoMet-dependent rRNA methyltransferase spb1; Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. (795 aa)
AFUA_6G05310Nucleolus protein required for cell viability, putative. (241 aa)
AFUA_5G03090Small nucleolar ribonucleoprotein complex subunit (Pwp2), putative. (926 aa)
AFUA_3G04110rRNA processing protein Bystin, putative. (497 aa)
Your Current Organism:
Aspergillus fumigatus
NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293
Server load: low (18%) [HD]