STRINGSTRING
AFUA_5G11870 AFUA_5G11870 AFUA_5G10890 AFUA_5G10890 AFUA_5G06080 AFUA_5G06080 AFUA_1G09530 AFUA_1G09530 AFUA_1G10410 AFUA_1G10410 AFUA_1G10540 AFUA_1G10540 AFUA_1G12520 AFUA_1G12520 AFUA_1G15120 AFUA_1G15120 AFUA_1G15310 AFUA_1G15310 AFUA_4G12430 AFUA_4G12430 psf3 psf3 AFUA_4G07230 AFUA_4G07230 AFUA_4G06970 AFUA_4G06970 AFUA_6G07700 AFUA_6G07700 AFUA_6G11130 AFUA_6G11130 AFUA_6G11410 AFUA_6G11410 AFUA_6G12910 AFUA_6G12910 ubc2 ubc2 AFUA_6G14670 AFUA_6G14670 AFUA_6G14690 AFUA_6G14690 AFUA_6G14720 AFUA_6G14720 AFUA_1G03920 AFUA_1G03920 AFUA_1G06360 AFUA_1G06360 AFUA_2G05470 AFUA_2G05470 AFUA_2G05850 AFUA_2G05850 AFUA_2G06320 AFUA_2G06320 AFUA_7G05890 AFUA_7G05890 AFUA_7G05280 AFUA_7G05280 AFUA_3G02390 AFUA_3G02390 slx1 slx1 AFUA_5G02520 AFUA_5G02520 AFUA_6G03970 AFUA_6G03970 AFUA_6G02700 AFUA_6G02700 AFUA_6G02530 AFUA_6G02530 AFUA_7G02200 AFUA_7G02200 AFUA_1G14695 AFUA_1G14695 AFUA_1G10355 AFUA_1G10355 AFUA_2G09060 AFUA_2G09060 MCM7 MCM7 psf2 psf2 AFUA_2G12940 AFUA_2G12940 AFUA_3G14460 AFUA_3G14460 AFUA_3G14010 AFUA_3G14010 AFUA_3G13260 AFUA_3G13260 mus81 mus81 sld2 sld2 AFUA_3G08800 AFUA_3G08800 AFUA_3G06780 AFUA_3G06780 AFUA_3G05540 AFUA_3G05540 AFUA_3G05440 AFUA_3G05440 AFUA_5G12010 AFUA_5G12010
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AFUA_5G11870WD repeat protein. (1051 aa)
AFUA_5G10890DNA helicase; Belongs to the MCM family. (956 aa)
AFUA_5G06080DNA repair protein Swi5/Sae3, putative. (114 aa)
AFUA_1G09530Uncharacterized protein. (724 aa)
AFUA_1G10410DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (348 aa)
AFUA_1G10540SIR2 family histone deacetylase (Hst4), putative. (614 aa)
AFUA_1G12520DNA repair protein (Rad57), putative. (647 aa)
AFUA_1G15120DsDNA-dependent ATPase (Rad54b), putative. (969 aa)
AFUA_1G15310DNA replication initiation factor Cdc45. (860 aa)
AFUA_4G12430PSF1 domain protein. (253 aa)
psf3DNA replication complex GINS protein psf3; The GINS complex plays an essential role in the initiation of DNA replication. (178 aa)
AFUA_4G07230ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (538 aa)
AFUA_4G06970RAD52 DNA repair protein RADC. (564 aa)
AFUA_6G07700Chromosomal organization and DNA repair protein Mms21, putative. (497 aa)
AFUA_6G11130Possible replication factor-a protein. (289 aa)
AFUA_6G11410Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (784 aa)
AFUA_6G12910DsDNA-dependent ATPase Rad54, putative. (807 aa)
ubc2Ubiquitin-conjugating enzyme E2 2; Catalyzes the covalent attachment of ubiquitin to other proteins. Plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation. Also involved in postreplication repair of UV-damaged DNA, in N-end rule-dependent protein degradation and in sporulation; Belongs to the ubiquitin-conjugating enzyme family. (151 aa)
AFUA_6G14670C2H2-type domain-containing protein. (146 aa)
AFUA_6G14690Telomere-associated RecQ helicase, putative. (352 aa)
AFUA_6G14720Telomere-associated RecQ helicase, putative. (1445 aa)
AFUA_1G03920DNA helicase; Belongs to the MCM family. (892 aa)
AFUA_1G06360MAGE domain-containing protein. (343 aa)
AFUA_2G05470Sister chromatid cohesion protein. (1772 aa)
AFUA_2G05850Double-strand-break repair protein rad21. (606 aa)
AFUA_2G06320Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (529 aa)
AFUA_7G05890Uncharacterized protein. (252 aa)
AFUA_7G05280Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (822 aa)
AFUA_3G02390DNA repair protein Nse1, putative. (336 aa)
slx1Structure-specific endonuclease subunit slx1; Catalytic subunit of the slx1-slx4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (423 aa)
AFUA_5G02520DNA helicase; Belongs to the MCM family. (718 aa)
AFUA_6G03970Cell cycle checkpoint protein (Hus1), putative. (373 aa)
AFUA_6G02700Structural maintenance of chromosome complex subunit SmcA. (1187 aa)
AFUA_6G02530DNA repair protein RAD1, putative. (975 aa)
AFUA_7G02200Meiotic recombination protein (Dmc1), putative; Belongs to the RecA family. (338 aa)
AFUA_1G14695DNA repair protein Dds20/Mei5, putative. (286 aa)
AFUA_1G1035526 proteasome complex subunit Sem1, putative. (83 aa)
AFUA_2G09060DNA helicase; Belongs to the MCM family. (1023 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (854 aa)
psf2DNA replication complex GINS protein psf2; The GINS complex plays an essential role in the initiation of DNA replication. Has a role in chromosome segregation (By similarity). (271 aa)
AFUA_2G12940Uncharacterized protein. (2275 aa)
AFUA_3G14460Rad51 family DNA repair protein, putative. (456 aa)
AFUA_3G14010DNA helicase; Belongs to the MCM family. (896 aa)
AFUA_3G13260Rad2-like endonuclease, putative. (869 aa)
mus81Crossover junction endonuclease mus81; Interacts with eme1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single- end invasion (SEI) (By similarity); Belongs to the XPF family. (596 aa)
sld2DNA replication regulator sld2; Has a role in the initiation of DNA replication. Required at S-phase checkpoint (By similarity); Belongs to the SLD2 family. (535 aa)
AFUA_3G08800DUF1767 domain-containing protein. (249 aa)
AFUA_3G06780DNA polymerase. (1656 aa)
AFUA_3G05540Cell cycle protein kinase, putative. (464 aa)
AFUA_3G05440DNA repair protein Rad18, putative. (1082 aa)
AFUA_5G12010Serine/threonine-protein phosphatase. (474 aa)
Your Current Organism:
Aspergillus fumigatus
NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293
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