15 items (Aspergillus fumigatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	iws1	Transcription factor iws1; Transcription factor involved in RNA polymerase II transcription regulation. May function in both SPT15/TBP post- recruitment and recruitment steps of transcription (By similarity). Belongs to the IWS1 family. (460 aa)
	AFUA_1G09180	Uncharacterized protein. (470 aa)
	AFUA_5G05870	RNA polymerase II transcription elongation factor (Ctr9), putative. (1195 aa)
	spt4	Transcription elongation factor spt4; The spt4-spt5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene (By similarity). (156 aa)
	AFUA_3G07670	Transcription elongation factor S-II. (304 aa)
	AFUA_2G05780	mRNA-capping enzyme subunit alpha; Second step of mRNA capping. Transfer of the GMP moiety of GTP to the 5'-end of RNA via an enzyme-GMP covalent reaction intermediate; Belongs to the eukaryotic GTase family. (415 aa)
	AFUA_3G11810	Uncharacterized protein. (605 aa)
	AFUA_2G01900	RNA polymerase II transcription elongation factor Rtf1p, putative. (607 aa)
	AFUA_1G07510	mRNA cleavage factor complex component Pcf11, putative. (654 aa)
	AFUA_6G14690	Telomere-associated RecQ helicase, putative. (352 aa)
	AFUA_6G14670	C2H2-type domain-containing protein. (146 aa)
	AFUA_4G07230	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (538 aa)
	AFUA_4G10030	DUF618 domain protein. (416 aa)
	AFUA_2G11000	Uncharacterized protein. (562 aa)
	AFUA_2G11190	Pol II transcription elongation factor subunit Cdc73, putative. (471 aa)

Your Current Organism:

Aspergillus fumigatus

NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFUA_1G07510	AFUA_3G07670	Q4WJ23	Q4WWZ7	mRNA cleavage factor complex component Pcf11, putative.	Transcription elongation factor S-II.	0.499
AFUA_1G07510	AFUA_4G10030	Q4WJ23	Q4WPP9	mRNA cleavage factor complex component Pcf11, putative.	DUF618 domain protein.	0.831
AFUA_1G07510	AFUA_5G05870	Q4WJ23	Q4WTR9	mRNA cleavage factor complex component Pcf11, putative.	RNA polymerase II transcription elongation factor (Ctr9), putative.	0.410
AFUA_1G07510	spt4	Q4WJ23	Q4WU00	mRNA cleavage factor complex component Pcf11, putative.	Transcription elongation factor spt4; The spt4-spt5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene (By similarity).	0.485
AFUA_1G09180	AFUA_2G01900	Q4WTI5	Q4WIG8	Uncharacterized protein.	RNA polymerase II transcription elongation factor Rtf1p, putative.	0.998
AFUA_1G09180	AFUA_2G11000	Q4WTI5	Q4X170	Uncharacterized protein.	Uncharacterized protein.	0.995
AFUA_1G09180	AFUA_2G11190	Q4WTI5	Q4X151	Uncharacterized protein.	Pol II transcription elongation factor subunit Cdc73, putative.	0.999
AFUA_1G09180	AFUA_3G07670	Q4WTI5	Q4WWZ7	Uncharacterized protein.	Transcription elongation factor S-II.	0.848
AFUA_1G09180	AFUA_3G11810	Q4WTI5	Q4WY51	Uncharacterized protein.	Uncharacterized protein.	0.956
AFUA_1G09180	AFUA_5G05870	Q4WTI5	Q4WTR9	Uncharacterized protein.	RNA polymerase II transcription elongation factor (Ctr9), putative.	0.999
AFUA_1G09180	iws1	Q4WTI5	Q4WSM6	Uncharacterized protein.	Transcription factor iws1; Transcription factor involved in RNA polymerase II transcription regulation. May function in both SPT15/TBP post- recruitment and recruitment steps of transcription (By similarity). Belongs to the IWS1 family.	0.792
AFUA_1G09180	spt4	Q4WTI5	Q4WU00	Uncharacterized protein.	Transcription elongation factor spt4; The spt4-spt5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene (By similarity).	0.954
AFUA_2G01900	AFUA_1G09180	Q4WIG8	Q4WTI5	RNA polymerase II transcription elongation factor Rtf1p, putative.	Uncharacterized protein.	0.998
AFUA_2G01900	AFUA_2G11000	Q4WIG8	Q4X170	RNA polymerase II transcription elongation factor Rtf1p, putative.	Uncharacterized protein.	0.998
AFUA_2G01900	AFUA_2G11190	Q4WIG8	Q4X151	RNA polymerase II transcription elongation factor Rtf1p, putative.	Pol II transcription elongation factor subunit Cdc73, putative.	0.998
AFUA_2G01900	AFUA_3G07670	Q4WIG8	Q4WWZ7	RNA polymerase II transcription elongation factor Rtf1p, putative.	Transcription elongation factor S-II.	0.829
AFUA_2G01900	AFUA_3G11810	Q4WIG8	Q4WY51	RNA polymerase II transcription elongation factor Rtf1p, putative.	Uncharacterized protein.	0.910
AFUA_2G01900	AFUA_5G05870	Q4WIG8	Q4WTR9	RNA polymerase II transcription elongation factor Rtf1p, putative.	RNA polymerase II transcription elongation factor (Ctr9), putative.	0.999
AFUA_2G01900	iws1	Q4WIG8	Q4WSM6	RNA polymerase II transcription elongation factor Rtf1p, putative.	Transcription factor iws1; Transcription factor involved in RNA polymerase II transcription regulation. May function in both SPT15/TBP post- recruitment and recruitment steps of transcription (By similarity). Belongs to the IWS1 family.	0.763
AFUA_2G01900	spt4	Q4WIG8	Q4WU00	RNA polymerase II transcription elongation factor Rtf1p, putative.	Transcription elongation factor spt4; The spt4-spt5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene (By similarity).	0.967