STRINGSTRING
AFUA_2G11070 AFUA_2G11070 AFUA_4G13150 AFUA_4G13150 pim1 pim1 AFUA_2G13650 AFUA_2G13650 AFUA_2G16100 AFUA_2G16100 AFUA_2G16130 AFUA_2G16130 rad18 rad18 AFUA_3G12280 AFUA_3G12280 AFUA_3G10280 AFUA_3G10280 AFUA_3G09110 AFUA_3G09110 sld2 sld2 AFUA_3G05440 AFUA_3G05440 AFUA_2G09560 AFUA_2G09560 AFUA_2G09290 AFUA_2G09290 AFUA_1G03920 AFUA_1G03920 AFUA_2G04860 AFUA_2G04860 AFUA_2G06320 AFUA_2G06320 rpc82 rpc82 AFUA_5G02610 AFUA_5G02610 AFUA_6G04350 AFUA_6G04350 AFUA_6G02700 AFUA_6G02700 AFUA_6G02530 AFUA_6G02530 AFUA_8G05290 AFUA_8G05290 AFUA_8G05300 AFUA_8G05300 AFUA_7G02200 AFUA_7G02200 AFUA_7G02190 AFUA_7G02190 AFUA_1G13060 AFUA_1G13060 AFUA_1G12640 AFUA_1G12640 AFUA_2G11660 AFUA_2G11660 AFUA_4G11477 AFUA_4G11477 AFUA_5G13330 AFUA_5G13330 AFUA_2G10730 AFUA_2G10730 AFUA_6G07500 AFUA_6G07500 acoA acoA ubc2 ubc2 AFUA_1G03410 AFUA_1G03410 AFUA_1G07620 AFUA_1G07620 AFUA_5G07890 AFUA_5G07890 AFUA_5G07120 AFUA_5G07120 AFUA_1G15310 AFUA_1G15310 AFUA_1G12520 AFUA_1G12520 AFUA_1G10410 AFUA_1G10410 AFUA_5G06400 AFUA_5G06400 AFUA_4G12680 AFUA_4G12680 AFUA_4G06260 AFUA_4G06260
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AFUA_2G11070Tyrosyl-DNA phosphodiesterase, putative. (564 aa)
AFUA_4G13150DUF159 domain protein. (415 aa)
pim1Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family. (1108 aa)
AFUA_2G13650Endonuclease/exonuclease/phosphatase family protein. (362 aa)
AFUA_2G16100Telomere-binding alpha subunit central domain protein. (635 aa)
AFUA_2G16130zf-C2HE domain-containing protein. (280 aa)
rad18Postreplication repair E3 ubiquitin-protein ligase rad18; E3 RING-finger protein, member of the UBC2/RAD6 epistasis group. Associates to the E2 ubiquitin conjugating enzyme UBC2/RAD6 to form the UBC2-RAD18 ubiquitin ligase complex involved in postreplicative repair (PRR) of damaged DNA. (418 aa)
AFUA_3G12280Recombination hotspot-binding protein (Translin), putative. (235 aa)
AFUA_3G10280DNA replication protein, putative. (792 aa)
AFUA_3G09110Uncharacterized protein. (289 aa)
sld2DNA replication regulator sld2; Has a role in the initiation of DNA replication. Required at S-phase checkpoint (By similarity); Belongs to the SLD2 family. (535 aa)
AFUA_3G05440DNA repair protein Rad18, putative. (1082 aa)
AFUA_2G09560Mitochondrial genome maintenance protein Mgm101, putative. (306 aa)
AFUA_2G09290Antigenic mitochondrial protein HSP60, putative; Belongs to the chaperonin (HSP60) family. (587 aa)
AFUA_1G03920DNA helicase; Belongs to the MCM family. (892 aa)
AFUA_2G04860DNA repair protein Rad4, putative. (916 aa)
AFUA_2G06320Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (529 aa)
rpc82DNA-directed RNA polymerase III subunit rpc3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs (By similarity). (629 aa)
AFUA_5G02610Cytochrome P450, putative; Belongs to the cytochrome P450 family. (466 aa)
AFUA_6G04350Uncharacterized protein. (277 aa)
AFUA_6G02700Structural maintenance of chromosome complex subunit SmcA. (1187 aa)
AFUA_6G02530DNA repair protein RAD1, putative. (975 aa)
AFUA_8G05290Uncharacterized protein. (477 aa)
AFUA_8G05300RNA polymerase II subunit 7. (139 aa)
AFUA_7G02200Meiotic recombination protein (Dmc1), putative; Belongs to the RecA family. (338 aa)
AFUA_7G02190Zinc knuckle nucleic acid binding protein, putative. (233 aa)
AFUA_1G13060Regulator of nonsense transcripts, putative. (1079 aa)
AFUA_1G12640Zinc metalloproteinase, putative. (341 aa)
AFUA_2G11660Rad4 family protein. (917 aa)
AFUA_4G11477Sucrase/ferredoxin-like family protein, putative. (368 aa)
AFUA_5G13330Uncharacterized protein. (344 aa)
AFUA_2G10730DNA polymerase. (1462 aa)
AFUA_6G07500DNA excision repair protein Rad2. (1130 aa)
acoAAconitate hydratase, mitochondrial; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate, a step in the citric acid cycle. Also catalyzes the reversible dehydration of (R)-homocitrate to cis-homoaconitate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. Belongs to the aconitase/IPM isomerase family. (787 aa)
ubc2Ubiquitin-conjugating enzyme E2 2; Catalyzes the covalent attachment of ubiquitin to other proteins. Plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation. Also involved in postreplication repair of UV-damaged DNA, in N-end rule-dependent protein degradation and in sporulation; Belongs to the ubiquitin-conjugating enzyme family. (151 aa)
AFUA_1G03410DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (500 aa)
AFUA_1G07620SAE2 domain-containing protein. (747 aa)
AFUA_5G07890SsDNA binding protein, putative. (149 aa)
AFUA_5G07120RNP domain protein. (352 aa)
AFUA_1G15310DNA replication initiation factor Cdc45. (860 aa)
AFUA_1G12520DNA repair protein (Rad57), putative. (647 aa)
AFUA_1G10410DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (348 aa)
AFUA_5G06400Uncharacterized protein. (862 aa)
AFUA_4G12680DNA repair protein Rad50. (1312 aa)
AFUA_4G06260Mating-type switch/DNA repair protein Swi10/Rad10, putative. (341 aa)
Your Current Organism:
Aspergillus fumigatus
NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.