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AFUA_8G05570 AFUA_8G05570 AFUA_5G03680 AFUA_5G03680 AFUA_3G02650 AFUA_3G02650 AFUA_3G01970 AFUA_3G01970 rgr1 rgr1 AFUA_2G06060 AFUA_2G06060 jhd1 jhd1 esa1 esa1 AFUA_2G04920 AFUA_2G04920 AFUA_2G04790 AFUA_2G04790 AFUA_2G03350 AFUA_2G03350 med6 med6 AFUA_6G02200 AFUA_6G02200 AFUA_6G02190 AFUA_6G02190 AFUA_8G05360 AFUA_8G05360 AFUA_5G03660 AFUA_5G03660 AFUA_7G01340 AFUA_7G01340 srb4 srb4 AFUA_1G13760 AFUA_1G13760 AFUA_1G14030 AFUA_1G14030 AFUA_8G00342 AFUA_8G00342 AFUA_5G13990 AFUA_5G13990 AFUA_6G05150 AFUA_6G05150 AFUA_5G01010 AFUA_5G01010 AFUA_2G07460 AFUA_2G07460 AFUA_2G08880 AFUA_2G08880 AFUA_2G10640 AFUA_2G10640 AFUA_2G11840 AFUA_2G11840 ptaB ptaB srb7 srb7 AFUA_2G13360 AFUA_2G13360 AFUA_2G13560 AFUA_2G13560 AFUA_2G14250 AFUA_2G14250 AFUA_2G16840 AFUA_2G16840 soh1 soh1 AFUA_3G09610 AFUA_3G09610 AFUA_3G06700 AFUA_3G06700 srb8 srb8 AFUA_5G09420 AFUA_5G09420 AFUA_5G09080 AFUA_5G09080 AFUA_5G06590 AFUA_5G06590 hir1 hir1 AFUA_1G10690 AFUA_1G10690 AFUA_1G14600 AFUA_1G14600 AFUA_1G15390 AFUA_1G15390 AFUA_1G16580 AFUA_1G16580 AFUA_1G17000 AFUA_1G17000 AFUA_4G13130 AFUA_4G13130 AFUA_4G11380 AFUA_4G11380 AFUA_4G10910 AFUA_4G10910 AFUA_4G10830 AFUA_4G10830 AFUA_4G08910 AFUA_4G08910 med8 med8 swc4 swc4 nut1 nut1 AFUA_4G06120 AFUA_4G06120 srb5 srb5 AFUA_6G09335 AFUA_6G09335 AFUA_6G09356 AFUA_6G09356 med7 med7 AFUA_6G12600 AFUA_6G12600 AFUA_1G04590 AFUA_1G04590 nut2 nut2 AFUA_1G06310 AFUA_1G06310
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AFUA_8G05570Transcription factor (Sin3), putative. (1497 aa)
AFUA_5G03680Transcription initiation factor TFIID complex 60 kDa subunit. (445 aa)
AFUA_3G02650MYB DNA binding domain protein. (315 aa)
AFUA_3G01970Uncharacterized protein. (401 aa)
rgr1Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (1093 aa)
AFUA_2G06060Transcriptional co-activator (Hfi1/Ada1), putative. (419 aa)
jhd1JmjC domain-containing histone demethylation protein 1; Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code. (1418 aa)
esa1Histone acetyltransferase esa1; Catalytic component of the NuA4 histone acetyltransferase (HAT) complex which is involved in epigenetic transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4, H3, H2B, H2A and H2A variant H2A.Z. Acetylates histone H4 to form H4K5ac, H4K8ac, H4K12ac and H4K16ac, histone H3 to form H3K14ac, histone H2B to form H2BK16ac, and histone H2A to form H2AK4ac and H2AK7ac. Acetylation of histone H4 is essential for DNA double- strand break repair through homologous recombination. Involved in cell cycle progression. Recru [...] (483 aa)
AFUA_2G04920Nuclear pore complex subunit Nup159, putative. (1466 aa)
AFUA_2G04790Mediator of RNA polymerase II transcription subunit 13; Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex. (1429 aa)
AFUA_2G03350MIZ zinc finger domain protein. (1147 aa)
med6Mediator of RNA polymerase II transcription subunit 6; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (324 aa)
AFUA_6G02200C2HC5 finger protein. (537 aa)
AFUA_6G02190SAGA-associated factor 11; Functions as component of the transcription regulatory histone acetylation (HAT) complex SAGA. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac). SAGA interacts with DNA [...] (338 aa)
AFUA_8G05360FAS1 domain-containing protein AFUA_8G05360. (234 aa)
AFUA_5G03660Transcription initiation factor TFIID subunit beta, putative. (401 aa)
AFUA_7G01340RPEL repeat protein. (145 aa)
srb4Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (639 aa)
AFUA_1G13760Cell wall anchored protein, putative. (561 aa)
AFUA_1G14030SAGA-like transcriptional regulatory complex subunit Spt3, putative. (362 aa)
AFUA_8G00342Uncharacterized protein. (310 aa)
AFUA_5G13990Endo-1,3(4)-beta-glucanase, putative. (477 aa)
AFUA_6G05150Transcriptional repressor TupA/RocA, putative. (702 aa)
AFUA_5G01010Uncharacterized protein. (312 aa)
AFUA_2G07460RNA polymerase II transcriptional coactivator, putative. (165 aa)
AFUA_2G08880Uncharacterized protein. (128 aa)
AFUA_2G10640Transcriptional adapter 2; Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and ADA. SAGA is involved in RNA polymerase II-dependent transcriptional regulation. (508 aa)
AFUA_2G11840Transcriptional corepressor Cyc8, putative. (867 aa)
ptaBTranscriptional activator ptaB; Transcriptional regulator that forms a complex with somA to control biofilm formation; Belongs to the MFG1 family. (729 aa)
srb7Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (207 aa)
AFUA_2G13360SNF2 family helicase/ATPase, putative. (1200 aa)
AFUA_2G13560Uncharacterized protein. (507 aa)
AFUA_2G14250CBF/NF-Y family transcription factor, putative. (247 aa)
AFUA_2G16840SWI-SNF complex subunit (Snf5), putative. (803 aa)
soh1Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (162 aa)
AFUA_3G09610Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (355 aa)
AFUA_3G06700COP9 signalosome subunit 2 (CsnB), putative. (504 aa)
srb8Mediator of RNA polymerase II transcription subunit 12; Component of the srb8-11 complex. The srb8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The srb8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex (By similarity). (1617 aa)
AFUA_5G09420Clock controled protein (Ccg-8), putative. (510 aa)
AFUA_5G09080Transcription factor (SPT8), putative. (612 aa)
AFUA_5G06590SNF2 family helicase, putative. (975 aa)
hir1Protein hir1; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (1043 aa)
AFUA_1G10690M protein repeat protein. (878 aa)
AFUA_1G14600Transcription initiation factor TFIID, 31kD subunit, putative. (306 aa)
AFUA_1G15390DUF1014 domain protein. (222 aa)
AFUA_1G16580Uncharacterized protein. (948 aa)
AFUA_1G17000Sin3-associated polypeptide Sap18, putative. (268 aa)
AFUA_4G13130Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (769 aa)
AFUA_4G11380Uncharacterized protein. (92 aa)
AFUA_4G10910Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (1058 aa)
AFUA_4G10830SNF2 family helicase, putative. (1180 aa)
AFUA_4G08910DUF3835 domain-containing protein. (592 aa)
med8Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (249 aa)
swc4SWR1-complex protein 4; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity). (588 aa)
nut1Mediator of RNA polymerase II transcription subunit 5; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (1007 aa)
AFUA_4G06120RSC complex subunit Sfh1, putative. (566 aa)
srb5Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (268 aa)
AFUA_6G09335SRF-type transcription factor family protein. (130 aa)
AFUA_6G09356MADS-box domain-containing protein. (103 aa)
med7Mediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (261 aa)
AFUA_6G12600WD repeat protein. (704 aa)
AFUA_1G04590Transcriptional regulator Ngg1, putative. (675 aa)
nut2Mediator of RNA polymerase II transcription subunit 10; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (159 aa)
AFUA_1G06310SWI-SNF complex subunit (BAF60b), putative. (508 aa)
Your Current Organism:
Aspergillus fumigatus
NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293
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