(63 nodes) Microtubule network (Aspergillus fumigatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AFUA_6G07120	Nuclear movement protein NudC. (200 aa)
	AFUA_2G07550	Serine/threonine protein kinase (Ark1), putative; Belongs to the protein kinase superfamily. (396 aa)
	nde1	Nuclear distribution protein nudE homolog 1; Required for nuclear migration within hyphae during vegetative growth. (621 aa)
	AFUA_2G11430	Spindle pole body component. (891 aa)
	AFUA_2G13450	Dynactin, putative. (1378 aa)
	AFUA_2G14280	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (769 aa)
	AFUA_2G14990	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
	AFUA_2G15750	Spindle pole body component. (826 aa)
	AFUA_2G16260	Microtubule associated protein (Ase1), putative. (768 aa)
	AFUA_3G13580	Dynamin GTPase, putative; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (712 aa)
	AFUA_3G12820	Kinesin family protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (849 aa)
	AFUA_3G11860	Microtubule associated protein EB1, putative. (278 aa)
	AFUA_3G11320	Spindle pole body component. (1035 aa)
	AFUA_3G08900	Tubulin-specific chaperone c, putative. (408 aa)
	AFUA_5G14070	Uncharacterized protein. (124 aa)
	AFUA_5G13190	Kinesin family protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1769 aa)
	AFUA_5G11810	Dynein heavy chain. (4368 aa)
	AFUA_5G08510	Dynein family protein. (307 aa)
	AFUA_5G05850	Uncharacterized protein. (465 aa)
	AFUA_1G08850	Septin; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (346 aa)
	AFUA_1G10910	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (466 aa)
	AFUA_1G11970	Mitochondrial dynamin GTPase (Msp1), putative; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (918 aa)
	AFUA_1G12670	Uncharacterized protein. (426 aa)
	stu1	Protein stu1; Microtubule binding protein that promotes the stabilization of dynamic microtubules. Required for mitotic spindle formation (By similarity). (1344 aa)
	AFUA_1G12820	Spindle pole body component. (947 aa)
	AFUA_1G14070	Chromosome segregation protein BIR1, putative. (870 aa)
	AFUA_1G15460	DnaJ domain protein. (885 aa)
	AFUA_1G16840	Translationally-controlled tumor protein homolog; Involved in protein synthesis. Involved in microtubule stabilization (By similarity); Belongs to the TCTP family. (179 aa)
	AFUA_4G14740	Serine/threonine protein kinase (Ark1), putative; Belongs to the protein kinase superfamily. (423 aa)
	AFUA_4G11870	Tubulin-specific chaperone, putative. (629 aa)
	AFUA_4G07620	Uncharacterized protein. (828 aa)
	AFUA_6G07630	Dynamin GTPase, putative; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (814 aa)
	AFUA_6G11890	Dynamin GTPase, putative; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (807 aa)
	AFUA_6G12700	DASH complex component Dam1, putative. (204 aa)
	AFUA_6G12840	Kinesin family protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (726 aa)
	nudF	Nuclear distribution protein nudF; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family. (467 aa)
	AFUA_6G12980	Spindle pole body component, putative. (911 aa)
	AFUA_6G14220	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (929 aa)
	AFUA_1G00730	DnaJ domain protein. (547 aa)
	AFUA_1G01140	Uncharacterized protein. (252 aa)
	AFUA_1G01640	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (457 aa)
	AFUA_1G02550	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
	AFUA_1G04850	Dynein light chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures. (94 aa)
	AFUA_1G04920	Calmodulin-binding protein Sha1, putative. (1015 aa)
	AFUA_1G07580	Cell polarity protein (Alp11), putative. (274 aa)
	AFUA_2G02280	Mitotic spindle biogenesis protein Spc19, putative. (170 aa)
	AFUA_2G03150	Kinesin family protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1009 aa)
	AFUA_7G08580	Dynamin GTPase, putative; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (737 aa)
	AFUA_7G03710	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (955 aa)
	AFUA_5G02730	Spindle pole body component. (888 aa)
	AFUA_5G02360	Vacuolar dynamin-like GTPase VpsA, putative; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (698 aa)
	AFUA_6G04100	Mis6 domain protein. (735 aa)
	AFUA_8G04140	Uncharacterized protein. (772 aa)
	AFUA_8G04660	Noc1p protein, putative. (679 aa)
	AFUA_8G06510	Uncharacterized protein. (172 aa)
	AFUA_8G02840	Dynamin-like GTPase Dnm1, putative; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (800 aa)
	AFUA_7G01400	Kinesin family protein (BimC), putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1190 aa)
	AFUA_7G00250	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
	AFUA_4G01160	Von Willebrand domain protein. (1062 aa)
	cbf5	H/ACA ribonucleoprotein complex subunit cbf5; Catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs and play a central role in ribosomal RNA processing. The H/ACA snoRNP complex also mediates pseudouridylation of other types of RNAs. Catalyzes pseudouridylation at position 93 in U2 snRNA. Also catalyzes pseudouridy [...] (487 aa)
	AFUA_1G13390	Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. (455 aa)
	AFUA_1G11450	Myosin class II heavy chain (MHC), putative. (2081 aa)
	AFUA_3G08920	Uncharacterized protein. (1002 aa)

Your Current Organism:

Aspergillus fumigatus

NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFUA_1G01140	AFUA_1G01640	Q4WKV6	Q4WKQ6	Uncharacterized protein.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.432
AFUA_1G01140	AFUA_1G02550	Q4WKV6	Q4WKG5	Uncharacterized protein.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.434
AFUA_1G01140	AFUA_1G04920	Q4WKV6	Q4WJS9	Uncharacterized protein.	Calmodulin-binding protein Sha1, putative.	0.517
AFUA_1G01140	AFUA_1G10910	Q4WKV6	Q4WT14	Uncharacterized protein.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.401
AFUA_1G01140	AFUA_1G13390	Q4WKV6	E9R808	Uncharacterized protein.	Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.	0.502
AFUA_1G01140	AFUA_2G03150	Q4WKV6	Q4WI43	Uncharacterized protein.	Kinesin family protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.644
AFUA_1G01140	AFUA_2G14990	Q4WKV6	Q4X021	Uncharacterized protein.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.434
AFUA_1G01140	AFUA_2G16260	Q4WKV6	Q4WZP1	Uncharacterized protein.	Microtubule associated protein (Ase1), putative.	0.612
AFUA_1G01140	AFUA_3G11860	Q4WKV6	Q4WY56	Uncharacterized protein.	Microtubule associated protein EB1, putative.	0.735
AFUA_1G01140	AFUA_3G12820	Q4WKV6	Q4WYF2	Uncharacterized protein.	Kinesin family protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.488
AFUA_1G01140	AFUA_4G07620	Q4WKV6	Q4WP09	Uncharacterized protein.	Uncharacterized protein.	0.413
AFUA_1G01140	AFUA_5G11810	Q4WKV6	Q4WVE4	Uncharacterized protein.	Dynein heavy chain.	0.671
AFUA_1G01140	AFUA_5G13190	Q4WKV6	Q4WVS9	Uncharacterized protein.	Kinesin family protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.483
AFUA_1G01140	AFUA_6G04100	Q4WKV6	Q4WDA9	Uncharacterized protein.	Mis6 domain protein.	0.401
AFUA_1G01140	AFUA_6G12840	Q4WKV6	Q4WLP0	Uncharacterized protein.	Kinesin family protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.581
AFUA_1G01140	AFUA_6G12980	Q4WKV6	Q4WLM6	Uncharacterized protein.	Spindle pole body component, putative.	0.573
AFUA_1G01140	AFUA_6G14220	Q4WKV6	Q4WLA6	Uncharacterized protein.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.453
AFUA_1G01140	AFUA_7G00250	Q4WKV6	Q4WA70	Uncharacterized protein.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.401
AFUA_1G01140	AFUA_7G01400	Q4WKV6	Q4WAI2	Uncharacterized protein.	Kinesin family protein (BimC), putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.932
AFUA_1G01140	AFUA_7G03710	Q4WKV6	Q4WG42	Uncharacterized protein.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.570