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| | AFUA_4G11602 | Cnn_1N domain-containing protein. (987 aa) |
| | AFUA_2G15905 | Sister chromatid cohesion protein Dcc1, putative. (394 aa) |
| | AFUA_5G12895 | SsDNA binding protein Ssb3, putative. (122 aa) |
| | AFUA_4G11477 | Sucrase/ferredoxin-like family protein, putative. (368 aa) |
| | AFUA_6G06530 | Uncharacterized protein. (249 aa) |
| | AFUA_6G06535 | Uncharacterized protein. (192 aa) |
| | AFUA_6G10965 | Apoptosis-inducing TAF9-like domain 1 family protein, putative. (110 aa) |
| | AFUA_1G03035 | HD superfamily hydrolase, putative. (243 aa) |
| | AFUA_1G03992 | CPSF_A domain-containing protein. (1285 aa) |
| | csm3 | Chromosome segregation in meiosis protein 3; Forms a fork protection complex (FPC) with tof1 and which is required for chromosome segregation during meiosis and DNA damage repair. FPC coordinates leading and lagging strand synthesis and moves with the replication fork. FPC stabilizes replication forks in a configuration that is recognized by replication checkpoint sensors (By similarity). (270 aa) |
| | tof1 | Topoisomerase 1-associated factor 1; Forms a fork protection complex (FPC) with csm3 and which is required for chromosome segregation during meiosis and DNA damage repair. FPC coordinates leading and lagging strand synthesis and moves with the replication fork. FPC stabilizes replication forks in a configuration that is recognized by replication checkpoint sensors (By similarity). (1176 aa) |
| | AFUA_7G01270 | DNA-directed polymerase kappa, putative. (614 aa) |
| | AFUA_8G04240 | Origin recognition complex subunit 3, putative. (698 aa) |
| | AFUA_6G04110 | CLPTM1 domain protein. (638 aa) |
| | AFUA_6G05040 | DNA replication factor C subunit Rfc4, putative. (348 aa) |
| | AFUA_5G01870 | DNA replication factor C subunit Rfc3, putative. (396 aa) |
| | AFUA_5G02430 | ATP dependent DNA ligase domain protein. (912 aa) |
| | AFUA_5G02520 | DNA helicase; Belongs to the MCM family. (718 aa) |
| | AFUA_7G03750 | Cell-cycle checkpoint protein kinase, putative; Belongs to the protein kinase superfamily. (409 aa) |
| | AFUA_7G04100 | Rtf2 domain-containing protein. (293 aa) |
| | AFUA_7G04310 | Cell division control protein; Belongs to the CDC6/cdc18 family. (647 aa) |
| | pob3 | FACT complex subunit pob3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (573 aa) |
| | AFUA_7G05480 | Sister chromatid cohesion factor (Chl12), putative. (940 aa) |
| | AFUA_2G06320 | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (529 aa) |
| | AFUA_2G06190 | DNA polymerase epsilon subunit B, putative. (762 aa) |
| | esa1 | Histone acetyltransferase esa1; Catalytic component of the NuA4 histone acetyltransferase (HAT) complex which is involved in epigenetic transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4, H3, H2B, H2A and H2A variant H2A.Z. Acetylates histone H4 to form H4K5ac, H4K8ac, H4K12ac and H4K16ac, histone H3 to form H3K14ac, histone H2B to form H2BK16ac, and histone H2A to form H2AK4ac and H2AK7ac. Acetylation of histone H4 is essential for DNA double- strand break repair through homologous recombination. Involved in cell cycle progression. Recru [...] (483 aa) |
| | AFUA_2G04030 | Chromatin assembly factor 1 subunit B, putative. (644 aa) |
| | slx4 | Structure-specific endonuclease subunit slx4; Regulatory subunit of the slx1-slx4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (811 aa) |
| | AFUA_2G02660 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (629 aa) |
| | AFUA_2G01910 | MRC1 domain-containing protein. (1284 aa) |
| | spt16 | FACT complex subunit spt16; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (1019 aa) |
| | AFUA_1G07600 | Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (363 aa) |
| | AFUA_1G07320 | Chromosome segregation protein (SepB), putative. (841 aa) |
| | AFUA_1G07180 | Ribonuclease H, putative. (410 aa) |
| | AFUA_1G04950 | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (323 aa) |
| | AFUA_1G04910 | Vezatin domain-containing protein. (629 aa) |
| | AFUA_1G04900 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (219 aa) |
| | AFUA_1G03920 | DNA helicase; Belongs to the MCM family. (892 aa) |
| | AFUA_1G03500 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (998 aa) |
| | AFUA_1G03410 | DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (500 aa) |
| | npl4 | Nuclear protein localization protein 4; Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity); Belongs to the NPL4 family. (652 aa) |
| | AFUA_1G02500 | Origin recognition complex subunit Orc5, putative. (541 aa) |
| | AFUA_1G02430 | Ubiquitin fusion degradation protein Ufd1, putative. (384 aa) |
| | AFUA_6G14720 | Telomere-associated RecQ helicase, putative. (1445 aa) |
| | AFUA_6G14690 | Telomere-associated RecQ helicase, putative. (352 aa) |
| | AFUA_6G14670 | C2H2-type domain-containing protein. (146 aa) |
| | AFUA_6G13080 | DEAD/DEAH box DNA helicase (Mer3), putative. (1439 aa) |
| | AFUA_6G11130 | Possible replication factor-a protein. (289 aa) |
| | AFUA_6G10560 | DNA polymerase delta subunit 4, putative. (193 aa) |
| | AFUA_6G10490 | Uncharacterized protein. (441 aa) |
| | AFUA_6G08210 | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (266 aa) |
| | AFUA_4G06690 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (859 aa) |
| | AFUA_4G07230 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (538 aa) |
| | AFUA_4G07970 | DNA polymerase delta subunit 2, putative. (554 aa) |
| | AFUA_4G08300 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1213 aa) |
| | AFUA_4G10650 | Uncharacterized protein. (198 aa) |
| | AFUA_4G11180 | AAA family ATPase, putative. (539 aa) |
| | psf3 | DNA replication complex GINS protein psf3; The GINS complex plays an essential role in the initiation of DNA replication. (178 aa) |
| | AFUA_4G12210 | DNA replication helicase Dna2, putative. (1657 aa) |
| | AFUA_4G12430 | PSF1 domain protein. (253 aa) |
| | ccr4 | Glucose-repressible alcohol dehydrogenase transcriptional effector; Acts as catalytic component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover. Ccr4 has 3'-5' RNase activity with a strong preference for polyadenylated substrates and also low exonuclease activity towards single-stranded DNA. Discovered because of its role in the control of ADH2 gene expression. It is required for the expression of genes involved in non-fermentative growth (By similarity); Belongs to [...] (696 aa) |
| | AFUA_1G15310 | DNA replication initiation factor Cdc45. (860 aa) |
| | AFUA_1G10720 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (789 aa) |
| | AFUA_1G10620 | SLD3 domain-containing protein. (933 aa) |
| | AFUA_1G10550 | CBF/NF-Y family transcription factor, putative. (282 aa) |
| | AFUA_1G10410 | DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (348 aa) |
| | clf1 | Pre-mRNA-splicing factor clf1; Involved in pre-mRNA splicing and cell cycle progression. Required for the spliceosome assembly and initiation of the DNA replication (By similarity). (676 aa) |
| | AFUA_1G10040 | HMG box protein, putative. (399 aa) |
| | AFUA_1G10020 | Ribonuclease H1, putative. (221 aa) |
| | AFUA_5G07890 | SsDNA binding protein, putative. (149 aa) |
| | AFUA_5G08110 | Origin recognition complex subunit 2, putative. (559 aa) |
| | AFUA_5G10620 | Histone-like transcription factor, putative. (190 aa) |
| | AFUA_5G10820 | Mitochondrial ATP-dependent RNA helicase Suv3, putative. (765 aa) |
| | AFUA_5G10890 | DNA helicase; Belongs to the MCM family. (956 aa) |
| | AFUA_5G11690 | Protein tyrosine phosphatase Pps1, putative. (551 aa) |
| | lig4 | DNA ligase 4; Involved in ds DNA break repair. Has a role in non-homologous integration (NHI) pathways where it is required in the final step of non-homologous end-joining; Belongs to the ATP-dependent DNA ligase family. (979 aa) |
| | AFUA_5G12350 | Ribonucleotide reductase small subunit RnrA, putative. (405 aa) |
| | AFUA_5G12640 | DNA polymerase gamma. (1135 aa) |
| | AFUA_5G13020 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (617 aa) |
| | AFUA_5G13220 | ERCC4 domain-containing protein. (649 aa) |
| | PIF1 | ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (788 aa) |
| | AFUA_5G13380 | BRCT domain protein. (786 aa) |
| | AFUA_5G13640 | Thioredoxin, putative. (565 aa) |
| | AFUA_5G14820 | Replication factor C subunit. (389 aa) |
| | AFUA_3G05540 | Cell cycle protein kinase, putative. (464 aa) |
| | chl1 | ATP-dependent DNA helicase chl1; ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (By similarity). May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (By similarity). Has a specific role in chromosome segregation during meiosis II (By similarity). (782 aa) |
| | fen1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (395 aa) |
| | AFUA_3G06780 | DNA polymerase. (1656 aa) |
| | AFUA_3G08300 | DNA replication factor C subunit Rfc2, putative. (394 aa) |
| | AFUA_3G09020 | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (522 aa) |
| | sld2 | DNA replication regulator sld2; Has a role in the initiation of DNA replication. Required at S-phase checkpoint (By similarity); Belongs to the SLD2 family. (535 aa) |
| | AFUA_3G09110 | Uncharacterized protein. (289 aa) |
| | pol2 | DNA polymerase epsilon catalytic subunit A; DNA polymerase II participates in chromosomal DNA replication. (2230 aa) |
| | AFUA_3G10280 | DNA replication protein, putative. (792 aa) |
| | AFUA_3G11140 | DNA ligase. (833 aa) |
| | AFUA_3G13260 | Rad2-like endonuclease, putative. (869 aa) |
| | AFUA_3G14010 | DNA helicase; Belongs to the MCM family. (896 aa) |
| | AFUA_2G17190 | AAA domain-containing protein. (1129 aa) |
| | AFUA_2G17050 | Nucleolar complex-associated protein 3; Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm. Belongs to the CBF/MAK21 family. (692 aa) |
| | AFUA_2G16710 | Uncharacterized protein. (438 aa) |
| | AFUA_2G16600 | DNA polymerase. (1105 aa) |
| | AFUA_2G14920 | Protein kinase, putative. (1028 aa) |
| | AFUA_2G12940 | Uncharacterized protein. (2275 aa) |
| | AFUA_2G12250 | DNA replication factor C subunit Rfc5, putative. (294 aa) |
| | AFUA_2G12220 | Replication factor C subunit 1. (1085 aa) |
| | AFUA_2G11170 | Origin recognition complex subunit Orc4, putative. (704 aa) |
| | psf2 | DNA replication complex GINS protein psf2; The GINS complex plays an essential role in the initiation of DNA replication. Has a role in chromosome segregation (By similarity). (271 aa) |
| | AFUA_2G10730 | DNA polymerase. (1462 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (854 aa) |
| | AFUA_2G09730 | Uncharacterized protein. (319 aa) |
| | AFUA_2G09060 | DNA helicase; Belongs to the MCM family. (1023 aa) |
| | AFUA_2G09010 | DNA ligase. (909 aa) |
