STRINGSTRING
AFUA_1G11720 AFUA_1G11720 AFUA_4G07835 AFUA_4G07835 AFUA_6G05174 AFUA_6G05174 AFUA_1G11870 AFUA_1G11870 AFUA_1G11730 AFUA_1G11730 AFUA_1G13130 AFUA_1G13130 AFUA_2G17110 AFUA_2G17110 AFUA_1G13330 AFUA_1G13330 AFUA_1G13720 AFUA_1G13720 AFUA_6G11190 AFUA_6G11190 AFUA_4G01260 AFUA_4G01260 AFUA_4G04620 AFUA_4G04620 AFUA_4G04310 AFUA_4G04310 AFUA_4G04100 AFUA_4G04100 AFUA_4G03990 AFUA_4G03990 AFUA_4G03870 AFUA_4G03870 AFUA_4G03100 AFUA_4G03100 AFUA_7G01230 AFUA_7G01230 AFUA_7G01510 AFUA_7G01510 AFUA_7G01860 AFUA_7G01860 AFUA_7G02270 AFUA_7G02270 vps10 vps10 pfa4 pfa4 AFUA_8G05240 AFUA_8G05240 AFUA_8G05160 AFUA_8G05160 yos9 yos9 AFUA_8G04260 AFUA_8G04260 AFUA_8G04140 AFUA_8G04140 AFUA_6G02130 AFUA_6G02130 AFUA_6G02420 AFUA_6G02420 AFUA_6G02870 AFUA_6G02870 egd2 egd2 AFUA_6G03850 AFUA_6G03850 AFUA_6G03990 AFUA_6G03990 AFUA_6G04010 AFUA_6G04010 AFUA_6G04150 AFUA_6G04150 mmm1 mmm1 AFUA_6G04870 AFUA_6G04870 AFUA_6G05050 AFUA_6G05050 AFUA_6G05110 AFUA_6G05110 AFUA_6G05290 AFUA_6G05290 AFUA_5G00230 AFUA_5G00230 AFUA_5G01180 AFUA_5G01180 AFUA_5G01960 AFUA_5G01960 AFUA_5G02200 AFUA_5G02200 AFUA_5G02360 AFUA_5G02360 AFUA_5G02900 AFUA_5G02900 AFUA_5G03220 AFUA_5G03220 AFUA_5G03630 AFUA_5G03630 AFUA_5G03640 AFUA_5G03640 AFUA_5G03880 AFUA_5G03880 AFUA_5G04320 AFUA_5G04320 AFUA_3G04060 AFUA_3G04060 AFUA_3G03520 AFUA_3G03520 AFUA_3G02213 AFUA_3G02213 AFUA_3G02210 AFUA_3G02210 AFUA_3G00820 AFUA_3G00820 AFUA_7G03640 AFUA_7G03640 AFUA_7G04150 AFUA_7G04150 AFUA_7G04260 AFUA_7G04260 AFUA_7G04460 AFUA_7G04460 AFUA_7G04470 AFUA_7G04470 mia40 mia40 AFUA_7G05970 AFUA_7G05970 AFUA_7G06040 AFUA_7G06040 AFUA_7G08630 AFUA_7G08630 AFUA_2G05890 AFUA_2G05890 AFUA_2G05440 AFUA_2G05440 mon1 mon1 vps27 vps27 hse1 hse1 AFUA_2G04620 AFUA_2G04620 AFUA_2G04610 AFUA_2G04610 AFUA_2G04270 AFUA_2G04270 tim50 tim50 pam18 pam18 AFUA_2G02610 AFUA_2G02610 AFUA_2G02560 AFUA_2G02560 AFUA_2G02500 AFUA_2G02500 AFUA_2G02430 AFUA_2G02430 AFUA_2G01990 AFUA_2G01990 AFUA_2G01660 AFUA_2G01660 AFUA_2G01570 AFUA_2G01570 AFUA_2G01130 AFUA_2G01130 tim9 tim9 AFUA_1G07420 AFUA_1G07420 AFUA_1G06880 AFUA_1G06880 AFUA_1G06790 AFUA_1G06790 AFUA_1G06680 AFUA_1G06680 AFUA_1G06420 AFUA_1G06420 AFUA_1G06030 AFUA_1G06030 sar1 sar1 AFUA_1G04930 AFUA_1G04930 AFUA_1G04890 AFUA_1G04890 tim10 tim10 AFUA_1G03940 AFUA_1G03940 AFUA_1G03590 AFUA_1G03590 AFUA_1G03560 AFUA_1G03560 sec23 sec23 npl4 npl4 AFUA_1G02430 AFUA_1G02430 AFUA_1G02170 AFUA_1G02170 pam17 pam17 AFUA_1G00230 AFUA_1G00230 AFUA_6G13300 AFUA_6G13300 AFUA_6G13120 AFUA_6G13120 AFUA_6G13020 AFUA_6G13020 sec24 sec24 AFUA_6G12430 AFUA_6G12430 AFUA_6G11380 AFUA_6G11380 AFUA_6G10700 AFUA_6G10700 AFUA_6G10630 AFUA_6G10630 AFUA_6G10410 AFUA_6G10410 AFUA_6G10360 AFUA_6G10360 AFUA_6G09990 AFUA_6G09990 AFUA_6G09390 AFUA_6G09390 oct1 oct1 AFUA_6G08230 AFUA_6G08230 swf1 swf1 AFUA_6G07560 AFUA_6G07560 sec13 sec13 AFUA_4G07110 AFUA_4G07110 AFUA_4G07430 AFUA_4G07430 AFUA_4G07700 AFUA_4G07700 AFUA_4G08040 AFUA_4G08040 AFUA_4G10020 AFUA_4G10020 AFUA_4G10040 AFUA_4G10040 AFUA_4G10180 AFUA_4G10180 AFUA_4G10200 AFUA_4G10200 AFUA_4G10710 AFUA_4G10710 AFUA_4G11560 AFUA_4G11560 tim54 tim54 AFUA_4G11940 AFUA_4G11940 AFUA_4G12060 AFUA_4G12060 AFUA_4G12070 AFUA_4G12070 AFUA_4G12080 AFUA_4G12080 AFUA_4G12290 AFUA_4G12290 erv25 erv25 AFUA_4G13490 AFUA_4G13490 AFUA_1G17490 AFUA_1G17490 AFUA_1G16970 AFUA_1G16970 AFUA_1G16820 AFUA_1G16820 AFUA_1G16320 AFUA_1G16320 AFUA_1G15900 AFUA_1G15900 AFUA_1G15720 AFUA_1G15720 AFUA_1G15400 AFUA_1G15400 AFUA_1G14940 AFUA_1G14940 ssh4 ssh4 mdm12 mdm12 AFUA_1G14780 AFUA_1G14780 AFUA_1G14200 AFUA_1G14200 AFUA_1G13180 AFUA_1G13180 AFUA_1G12540 AFUA_1G12540 AFUA_1G11860 AFUA_1G11860 AFUA_1G11470 AFUA_1G11470 AFUA_1G10970 AFUA_1G10970 AFUA_1G10950 AFUA_1G10950 AFUA_1G10640 AFUA_1G10640 AFUA_1G10497 AFUA_1G10497 AFUA_1G09840 AFUA_1G09840 AFUA_1G09830 AFUA_1G09830 AFUA_1G09820 AFUA_1G09820 hulA hulA AFUA_1G09480 AFUA_1G09480 AFUA_1G08970 AFUA_1G08970 AFUA_1G08790 AFUA_1G08790 AFUA_5G05800 AFUA_5G05800 AFUA_5G06300 AFUA_5G06300 AFUA_5G06450 AFUA_5G06450 AFUA_5G06550 AFUA_5G06550 AFUA_5G06960 AFUA_5G06960 AFUA_5G07150 AFUA_5G07150 AFUA_5G07920 AFUA_5G07920 AFUA_5G07930 AFUA_5G07930 AFUA_5G08060 AFUA_5G08060 AFUA_5G08130 AFUA_5G08130 atg3 atg3 pfa5 pfa5 AFUA_5G09020 AFUA_5G09020 AFUA_5G09660 AFUA_5G09660 AFUA_5G10730 AFUA_5G10730 AFUA_5G10810 AFUA_5G10810 AFUA_5G11100 AFUA_5G11100 AFUA_5G11360 AFUA_5G11360 AFUA_5G11750 AFUA_5G11750 AFUA_5G12170 AFUA_5G12170 AFUA_5G12180 AFUA_5G12180 AFUA_5G12760 AFUA_5G12760 AFUA_5G12820 AFUA_5G12820 mdmB mdmB AFUA_5G13600 AFUA_5G13600 AFUA_5G13890 AFUA_5G13890 AFUA_3G05820 AFUA_3G05820 erf2 erf2 AFUA_3G06850 AFUA_3G06850 AFUA_3G06901 AFUA_3G06901 AFUA_3G07590 AFUA_3G07590 AFUA_3G07630 AFUA_3G07630 AFUA_3G08230 AFUA_3G08230 AFUA_3G08590 AFUA_3G08590 AFUA_3G08730 AFUA_3G08730 AFUA_3G08780 AFUA_3G08780 AFUA_3G08840 AFUA_3G08840 AFUA_3G08850 AFUA_3G08850 AFUA_3G08970 AFUA_3G08970 AFUA_3G09700 AFUA_3G09700 AFUA_3G09810 AFUA_3G09810 AFUA_3G10060 AFUA_3G10060 AFUA_3G10190 AFUA_3G10190 AFUA_3G10360 AFUA_3G10360 AFUA_3G10460 AFUA_3G10460 AFUA_3G10650 AFUA_3G10650 AFUA_3G10740 AFUA_3G10740 AFUA_3G10940 AFUA_3G10940 AFUA_3G11090 AFUA_3G11090 AFUA_3G11200 AFUA_3G11200 get3 get3 AFUA_3G12080 AFUA_3G12080 AFUA_3G12360 AFUA_3G12360 AFUA_3G12370 AFUA_3G12370 sec11 sec11 AFUA_3G13000 AFUA_3G13000 AFUA_3G13840 AFUA_3G13840 AFUA_3G14320 AFUA_3G14320 AFUA_3G14380 AFUA_3G14380 mvp1 mvp1 AFUA_2G16730 AFUA_2G16730 AFUA_2G16670 AFUA_2G16670 pfa3 pfa3 AFUA_2G16090 AFUA_2G16090 AFUA_2G15870 AFUA_2G15870 AFUA_2G15820 AFUA_2G15820 AFUA_2G15570 AFUA_2G15570 AFUA_2G14760 AFUA_2G14760 AFUA_2G14190 AFUA_2G14190 AFUA_2G13750 AFUA_2G13750 AFUA_2G13040 AFUA_2G13040 sec31 sec31 AFUA_2G12870 AFUA_2G12870 AFUA_2G12580 AFUA_2G12580 tim13 tim13 bro1 bro1 AFUA_2G10980 AFUA_2G10980 AFUA_2G10610 AFUA_2G10610 AFUA_2G10340 AFUA_2G10340 AFUA_2G10150 AFUA_2G10150 AFUA_2G10010 AFUA_2G10010 tim21 tim21 AFUA_2G09290 AFUA_2G09290 AFUA_2G09180 AFUA_2G09180 AFUA_2G08850 AFUA_2G08850 AFUA_2G07600 AFUA_2G07600
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AFUA_1G11720Uncharacterized protein. (563 aa)
AFUA_4G07835Nuclear transport factor 2 domain protein, putative. (162 aa)
AFUA_6G05174TOM complex component Tom7, putative. (53 aa)
AFUA_1G11870Mitochondrial processing peptidase alpha subunit, putative; Belongs to the peptidase M16 family. (581 aa)
AFUA_1G11730ADP-ribosylation factor, putative; Belongs to the small GTPase superfamily. Arf family. (183 aa)
AFUA_1G13130Uncharacterized protein. (346 aa)
AFUA_2G17110Cell division control protein Cdc48; Belongs to the AAA ATPase family. (819 aa)
AFUA_1G13330Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (388 aa)
AFUA_1G13720Intracellular protein transport protein (UsoA), putative. (1061 aa)
AFUA_6G11190Protein kinase (VPS15), putative. (1637 aa)
AFUA_4G01260Mitochondrial chaperone ATPase (Bcs1), putative; Belongs to the AAA ATPase family. (520 aa)
AFUA_4G04620Mitochondrial outer membrane protein (Sam50), putative. (544 aa)
AFUA_4G04310AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (939 aa)
AFUA_4G04100Vacuolar protein sorting protein (Vps36), putative. (537 aa)
AFUA_4G03990Membrane-spanning ATPase, putative; Belongs to the AAA ATPase family. (419 aa)
AFUA_4G03870Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (260 aa)
AFUA_4G03100Ras-like GTP-binding protein, putative. (294 aa)
AFUA_7G01230DnaJ domain protein. (480 aa)
AFUA_7G01510SNARE domain protein. (279 aa)
AFUA_7G01860Heat shock protein (Sti1), putative. (585 aa)
AFUA_7G02270Trafficking protein particle complex subunit BET3. (189 aa)
vps10Vacuolar protein sorting/targeting protein 10; Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A. Executes multiple rounds of sorting by cycling between the late Golgi and a prevacuolar endosome-like compartment (By similarity); Belongs to the VPS10-related sortilin family. (1487 aa)
pfa4Palmitoyltransferase pfa4; Mediates the reversible addition of palmitate to target proteins, thereby regulating their membrane association and biological function; Belongs to the DHHC palmitoyltransferase family. PFA4 subfamily. (428 aa)
AFUA_8G05240Peroxisomal targeting signal-1 receptor (PEX5), putaitve. (569 aa)
AFUA_8G05160Peroxisomal membrane protein (Pex13), putative. (444 aa)
yos9Protein OS-9 homolog; Lectin involved in the quality control of the secretory pathway. As a member of the endoplasmic reticulum-associated degradation lumenal (ERAD-L) surveillance system, targets misfolded endoplasmic reticulum lumenal glycoproteins for degradation (By similarity). (520 aa)
AFUA_8G04260Translocation protein (Sec66), putative. (266 aa)
AFUA_8G04140Uncharacterized protein. (772 aa)
AFUA_6G02130Rab proteins geranylgeranyltransferase; Belongs to the Rab GDI family. (525 aa)
AFUA_6G02420Ubiquitin conjugating enzyme (UbcM), putative; Belongs to the ubiquitin-conjugating enzyme family. (149 aa)
AFUA_6G02870Uncharacterized protein. (399 aa)
egd2Nascent polypeptide-associated complex subunit alpha; Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of th [...] (204 aa)
AFUA_6G03850Signal sequence receptor alpha subunit, putative. (649 aa)
AFUA_6G03990GAS2 domain protein. (1494 aa)
AFUA_6G04010Chromosome segregation protein Cse1, putative. (983 aa)
AFUA_6G04150Protein transport protein sec22; Belongs to the synaptobrevin family. (215 aa)
mmm1Maintenance of mitochondrial morphology protein 1; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The mdm12-mmm1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta- barrel proteins, and acts in a late step after the SAM complex. The mdm10-mdm12-mmm1 su [...] (496 aa)
AFUA_6G04870Vacuolar protein sorting-associated protein VpsB; Belongs to the STXBP/unc-18/SEC1 family. (595 aa)
AFUA_6G05050DUF410 domain protein. (346 aa)
AFUA_6G05110Mitochondrial import receptor subunit (Tom40), putative. (355 aa)
AFUA_6G05290Exocyst complex component SEC15; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (745 aa)
AFUA_5G00230Uncharacterized protein. (582 aa)
AFUA_5G01180RAN small monomeric GTPase (Ran), putative. (480 aa)
AFUA_5G01960Phosphate transporter (Pho88), putative. (186 aa)
AFUA_5G02200Mitochondrial import inner membrane translocase subunit (TIM22), putative. (175 aa)
AFUA_5G02360Vacuolar dynamin-like GTPase VpsA, putative; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (698 aa)
AFUA_5G02900SNARE domain protein. (251 aa)
AFUA_5G03220Signal peptidase subunit 3. (252 aa)
AFUA_5G03630Uncharacterized protein. (130 aa)
AFUA_5G03640Mitochondrial export translocase Oxa1, putative. (436 aa)
AFUA_5G03880Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (522 aa)
AFUA_5G04320Secretion related GTPase SrgB/Ypt1. (201 aa)
AFUA_3G04060SNF7 family protein Fti1/Did2, putative. (209 aa)
AFUA_3G03520Integral membrane protein. (446 aa)
AFUA_3G02213Uncharacterized protein. (339 aa)
AFUA_3G02210C6 transcription factor, putative. (365 aa)
AFUA_3G00820Putative exported protein. (415 aa)
AFUA_7G03640AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane. (953 aa)
AFUA_7G04150Cochaperone Pam16. (173 aa)
AFUA_7G04260Peroxisome biosynthesis protein (Peroxin-10), putative. (377 aa)
AFUA_7G04460Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C- terminal sequence -XXCC, -XCXC and -CCXX. (304 aa)
AFUA_7G04470Uncharacterized protein. (672 aa)
mia40Mitochondrial intermembrane space import and assembly protein 40; Required for the import and folding of small cysteine- containing proteins (small Tim) in the mitochondrial intermembrane space (IMS). Forms a redox cycle with ERV1 that involves a disulfide relay system. Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitochondria. The oxidized form of MIA40 forms a transient intermolecular disulfide bridge with the reduced precursor protein, resulting in oxidation of the precursor protein that now contains an intramolecular disulfide bond [...] (297 aa)
AFUA_7G05970mRNA transport regulator (Mtr10), putative. (977 aa)
AFUA_7G06040Uncharacterized membrane protein. (184 aa)
AFUA_7G08630Uncharacterized protein. (459 aa)
AFUA_2G05890Cog4 domain-containing protein. (901 aa)
AFUA_2G05440CTLH domain-containing protein. (229 aa)
mon1Vacuolar fusion protein mon1; Required for multiple vacuole delivery pathways including the cytoplasm to vacuole transport (Cvt), autophagy, pexophagy and endocytosis; Belongs to the MON1/SAND family. (621 aa)
vps27Vacuolar protein sorting-associated protein 27; Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane. (729 aa)
hse1Class E vacuolar protein-sorting machinery protein hse1; Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB). (584 aa)
AFUA_2G04620Hsp70 chaperone BiP/Kar2, putative; Belongs to the heat shock protein 70 family. (672 aa)
AFUA_2G04610DUF967 domain protein. (188 aa)
AFUA_2G04270Mitochondrial inner membrane translocase subunit (TIM17), putative. (154 aa)
tim50Mitochondrial import inner membrane translocase subunit tim50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Required to direct preproteins in transit and direct them to the channel protein TIM23, and possibly facilitates transfer of the translocating proteins from the TOM complex to the TIM23 complex (By similarity). (501 aa)
pam18Mitochondrial import inner membrane translocase subunit tim14; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to stimulate activity of mtHSP70 (SSC1/sscA) (By similarity); Belongs to the TIM14 family. (105 aa)
AFUA_2G02610SNARE complex subunit (Vam7), putative. (383 aa)
AFUA_2G02560Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (916 aa)
AFUA_2G02500DUF2263 domain-containing protein. (271 aa)
AFUA_2G02430Mitochondrial genome maintenance protein Mgr2, putative. (108 aa)
AFUA_2G01990Signal recognition particle 14kD protein, putative. (139 aa)
AFUA_2G01660Mitochondrial outer membrane translocase receptor (TOM70), putative. (630 aa)
AFUA_2G01570AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (148 aa)
AFUA_2G01130Ubiquitin conjugating enzyme (UbcJ), putative; Belongs to the ubiquitin-conjugating enzyme family. (164 aa)
tim9Mitochondrial import inner membrane translocase subunit tim9; Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta- barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity); Belongs to the small Tim family. (90 aa)
AFUA_1G07420SNARE complex subunit (Bet1), putative. (169 aa)
AFUA_1G06880Mitochondrial export translocase Oxa2, putative. (342 aa)
AFUA_1G06790Importin beta-3 subunit, putative. (1095 aa)
AFUA_1G06680VHS domain protein. (642 aa)
AFUA_1G06420SNF7 family protein. (241 aa)
AFUA_1G06030AP-1 complex subunit gamma. (803 aa)
sar1Small COPII coat GTPase sar1; Small GTPase component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. Sar1 controls the coat assembly in a stepwise manner. Activated Sar1-GTP binds to membranes first and recruits the sec23/24 complex. These sec23/24-sar1 prebudding intermediates are then collected by the Sec13/31 complex as subunits polymerize to form coated trans [...] (189 aa)
AFUA_1G04930Uncharacterized protein. (711 aa)
AFUA_1G04890Translocon protein Sec61beta, putative. (131 aa)
tim10Mitochondrial import inner membrane translocase subunit tim10; Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta- barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity); Belongs to the small Tim family. (93 aa)
AFUA_1G03940Signal recognition particle subunit SRP68; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP68 family. (646 aa)
AFUA_1G03590Importin 11, putative. (1045 aa)
AFUA_1G03560Peroxisome biosynthesis protein (Peroxin-2), putative. (479 aa)
sec23Protein transport protein sec23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity). (780 aa)
npl4Nuclear protein localization protein 4; Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity); Belongs to the NPL4 family. (652 aa)
AFUA_1G02430Ubiquitin fusion degradation protein Ufd1, putative. (384 aa)
AFUA_1G02170ATP-dependent Clp protease, putative. (638 aa)
pam17Presequence translocated-associated motor subunit pam17, mitochondrial; Component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. (247 aa)
AFUA_1G00230Uncharacterized protein. (759 aa)
AFUA_6G13300GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (215 aa)
AFUA_6G13120Filament-forming protein (Tpr/p270), putative. (2009 aa)
AFUA_6G13020AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (185 aa)
sec24Protein transport protein sec24; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity). (919 aa)
AFUA_6G12430Ran-interacting protein Mog1, putative. (228 aa)
AFUA_6G11380Mitochondrial import receptor subunit (Tom20), putative. (169 aa)
AFUA_6G10700Chaperonin, putative; Belongs to the GroES chaperonin family. (122 aa)
AFUA_6G10630GPN-loop GTPase 2; Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family. (381 aa)
AFUA_6G10410E3 ubiquitin-protein ligase PEP5. (958 aa)
AFUA_6G10360Protein required for cell viability, putative. (994 aa)
AFUA_6G09990Importin beta-4 subunit, putative. (1095 aa)
AFUA_6G09390Uncharacterized protein. (719 aa)
oct1Mitochondrial intermediate peptidase; Cleaves proteins, imported into the mitochondrion, to their mature size. While most mitochondrial precursor proteins are processed to the mature form in one step by mitochondrial processing peptidase (MPP), the sequential cleavage by MIP of an octapeptide after initial processing by MPP is a required step for a subgroup of nuclear-encoded precursor proteins destined for the matrix or the inner membrane (By similarity). (801 aa)
AFUA_6G08230Mitochondrial import protein Zim17, putative. (195 aa)
swf1Palmitoyltransferase swf1; Palmitoyltransferase that targets several endosomal SNAREs. Palmitoylates the SNAREs at cysteine residues close to the cytoplasmic end of their transmembrane domain. May have a role in the cellular quality control of transmembrane domain-containing proteins (By similarity); Belongs to the DHHC palmitoyltransferase family. SWF1 subfamily. (379 aa)
AFUA_6G07560Transcription factor Rap1, putative. (315 aa)
sec13Protein transport protein sec13; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. It also functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport facto [...] (306 aa)
AFUA_4G07110SNARE domain protein; Belongs to the syntaxin family. (271 aa)
AFUA_4G07430UBX domain protein, putative. (519 aa)
AFUA_4G07700Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1693 aa)
AFUA_4G08040RAB GTPase Ypt5, putative. (218 aa)
AFUA_4G10020Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (242 aa)
AFUA_4G10040SNARE complex subunit (Tlg2), putative; Belongs to the syntaxin family. (390 aa)
AFUA_4G10180Signal recognition particle subunit SRP72; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP72 family. (647 aa)
AFUA_4G10200Transcription factor RfeF, putative. (675 aa)
AFUA_4G10710Vesicle transport v-snare protein, putative. (224 aa)
AFUA_4G11560Vacuolar protein sorting-associated protein; May be involved in recycling of membrane proteins between an endocytic compartment and the TGN; Belongs to the VPS13 family. (3187 aa)
tim54Mitochondrial import inner membrane translocase subunit tim54; Essential component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin- pore translocase that uses the membrane potential as external driving force (By similarity). (439 aa)
AFUA_4G11940DUF2263 domain-containing protein. (335 aa)
AFUA_4G12060Vacuolar protein sorting-associated protein 26, putative. (349 aa)
AFUA_4G12070Endosomal peripheral membrane protein (Mon2), putative. (1688 aa)
AFUA_4G12080Ubiquitin conjugating enzyme (MmsB), putative. (139 aa)
AFUA_4G12290ESCRT-II complex component (Vps25), putative. (195 aa)
erv25Endoplasmic reticulum vesicle protein 25; Constituent of COPII-coated endoplasmic reticulum-derived transport vesicles. Required for efficient transport of a subset of secretory proteins to the Golgi. Facilitates retrograde transport from the Golgi to the endoplasmic reticulum (By similarity); Belongs to the EMP24/GP25L family. (266 aa)
AFUA_4G13490AP-3 adaptor complex subunit mu, putative; Belongs to the adaptor complexes medium subunit family. (624 aa)
AFUA_1G17490Glucokinase regulator family protein, putative. (657 aa)
AFUA_1G16970ADP-ribosylation factor family protein. (249 aa)
AFUA_1G16820Signal recognition particle 19 kDa protein, putative. (257 aa)
AFUA_1G16320Vacuolar protein sorting-associated protein 28; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (244 aa)
AFUA_1G15900Importin beta-2 subunit, putative. (937 aa)
AFUA_1G15720Importin beta-1 subunit. (872 aa)
AFUA_1G15400Peroxisome biosynthesis protein (Peroxine-7), putative. (356 aa)
AFUA_1G14940Protein translocation complex componenet (Npl1), putative. (697 aa)
ssh4Protein ssh4; Components of the endosome-vacuole trafficking pathway that regulates nutrient transport. May be involved in processes which determine whether plasma membrane proteins are degraded or routed to the plasma membrane (By similarity); Belongs to the SSH4 family. (507 aa)
mdm12Mitochondrial distribution and morphology protein 12; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. Mdm12 is required for the interaction of the ER-resident membrane protein mmm1 and the outer mitochondrial membrane-resident beta-barrel protein mdm10. The mdm12-mmm1 subcomplex functions in the major beta-barrel assembly pat [...] (439 aa)
AFUA_1G14780BAP31 domain protein, putative. (212 aa)
AFUA_1G14200Mitochondrial processing peptidase beta subunit, putative; Belongs to the peptidase M16 family. (479 aa)
AFUA_1G13180Mitochondrial outer membrane protein (Sam35), putative. (296 aa)
AFUA_1G12540TMEM1 family protein, putative. (1443 aa)
AFUA_1G11860Mitochondrial import receptor subunit tom22. (143 aa)
AFUA_1G11470Endosomal cargo receptor (P24), putative. (218 aa)
AFUA_1G10970Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (955 aa)
AFUA_1G10950Vesicle-mediated transport protein Vid24, putative. (330 aa)
AFUA_1G10640GPN-loop GTPase 3; Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family. (293 aa)
AFUA_1G10497Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. (227 aa)
AFUA_1G09840Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family. (523 aa)
AFUA_1G09830Hsc70 cochaperone (SGT), putative. (341 aa)
AFUA_1G09820DUF1339 domain protein. (1069 aa)
hulAProbable E3 ubiquitin-protein ligase hulA; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Probably involved in the regulatory network controlling carbon source utilization. (813 aa)
AFUA_1G09480Vacuolar protein sorting-associated protein 29; Belongs to the VPS29 family. (195 aa)
AFUA_1G08970Uncharacterized protein. (441 aa)
AFUA_1G08790Exportin KapK. (1101 aa)
AFUA_5G05800Microsomal signal peptidase Spc12, putative. (102 aa)
AFUA_5G06300Peroxisomal membrane protein (Pex3), putative. (528 aa)
AFUA_5G06450Vacuolar protein sorting protein DigA. (961 aa)
AFUA_5G06550Filamentation protein (Rhf1), putative. (1156 aa)
AFUA_5G06960Uncharacterized protein. (212 aa)
AFUA_5G07150Vacuolar protein sorting-associated protein 17; Plays a role in vesicular protein sorting. Belongs to the VPS17 family. (591 aa)
AFUA_5G07920Erf4 domain-containing protein. (509 aa)
AFUA_5G07930AP-2 adaptor complex subunit mu, putative; Belongs to the adaptor complexes medium subunit family. (445 aa)
AFUA_5G08060Importin 13, putative. (1025 aa)
AFUA_5G08130Protein transport protein Sec61 alpha subunit, putative. (478 aa)
atg3Autophagy-related protein 3; E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt) and autophagy. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C- terminal Gly of atg8. The atg12-atg5 conjugate plays a role of an E3 and promotes the transfer of [...] (353 aa)
pfa5Palmitoyltransferase pfa5; Belongs to the DHHC palmitoyltransferase family. PFA5 subfamily. (443 aa)
AFUA_5G09020ER membrane protein Wsc4, putative. (330 aa)
AFUA_5G09660AP-1 adaptor complex subunit mu, putative; Belongs to the adaptor complexes medium subunit family. (446 aa)
AFUA_5G10730Rad60-SLD_2 domain-containing protein. (267 aa)
AFUA_5G10810Sec1 family superfamily; Belongs to the STXBP/unc-18/SEC1 family. (667 aa)
AFUA_5G11100DUF775 domain protein. (241 aa)
AFUA_5G11360AP-3 adaptor complex subunit beta, putative. (843 aa)
AFUA_5G11750Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. (932 aa)
AFUA_5G12170Uncharacterized protein. (808 aa)
AFUA_5G12180Ran-specific GTPase-activating protein 1, putative. (247 aa)
AFUA_5G12760CCCH zinc finger DNA binding protein. (429 aa)
AFUA_5G12820Mitochondrial inner membrane protease subunit 1, putative. (179 aa)
mdmBMitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. mdm10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the tom40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of tom40 with the recepto [...] (471 aa)
AFUA_5G13600Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology. (828 aa)
AFUA_5G13890SNF7 family protein. (229 aa)
AFUA_3G05820ZZ type zinc finger domain protein. (838 aa)
erf2Palmitoyltransferase erf2; Palmitoyltransferase specific for Ras proteins. (607 aa)
AFUA_3G06850Uncharacterized protein. (296 aa)
AFUA_3G06901Protein translocation complex subunit Sss1, putative. (88 aa)
AFUA_3G07590ER-Golgi SNARE complex subunit (Sed5), putative. (346 aa)
AFUA_3G07630Metallo-beta-lactamase superfamily protein. (179 aa)
AFUA_3G08230MRS7 family protein. (614 aa)
AFUA_3G08590Uncharacterized protein. (125 aa)
AFUA_3G08730Endosome-associated ubiquitin isopeptidase (AmsH), putative. (532 aa)
AFUA_3G08780Nuclear import and export protein Msn5, putative. (1072 aa)
AFUA_3G08840Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. (1212 aa)
AFUA_3G08850Sulfhydryl oxidase. (220 aa)
AFUA_3G08970AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (746 aa)
AFUA_3G09700Sec23/Sec24 family protein. (1019 aa)
AFUA_3G09810Golgi transport complex component Cog5, putaitve. (476 aa)
AFUA_3G10060Dor1-like family protein. (478 aa)
AFUA_3G10190Peroxisomal membrane anchor protein (Pex14), putative. (416 aa)
AFUA_3G10360Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (878 aa)
AFUA_3G10460Nuclear transport factor NTF-2, putative. (124 aa)
AFUA_3G10650Glutamate carboxypeptidase Tre2, putative. (907 aa)
AFUA_3G10740RAB GTPase Vps21/Ypt51, putative. (262 aa)
AFUA_3G10940Peroxisomal membrane protein receptor Pex19, putative. (389 aa)
AFUA_3G11090Golgi complex component Cog3, putative. (756 aa)
AFUA_3G11200Vacuolar assembly protein, putative. (1298 aa)
get3ATPase get3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...] (340 aa)
AFUA_3G12080ADP-ribosylation factor 6, putative; Belongs to the small GTPase superfamily. Arf family. (184 aa)
AFUA_3G12360Uncharacterized protein. (514 aa)
AFUA_3G12370V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (161 aa)
sec11Signal peptidase complex catalytic subunit sec11; Catalytic component of the signal peptidase complex (SPC), which catalyzes the cleavage of N-terminal signal sequences of proteins targeted to the endoplasmic reticulum. Signal peptide cleavage occurs during the translocation (cotranslationally or post-translationally) through the translocon pore into the endoplasmic reticulum (By similarity). (192 aa)
AFUA_3G13000Mitochondrial chaperone BCS1, putative; Belongs to the AAA ATPase family. (499 aa)
AFUA_3G13840Mitochondrial inner membrane protease subunit Imp2, putative. (297 aa)
AFUA_3G14320Golgi transport protein Sly1, putative; Belongs to the STXBP/unc-18/SEC1 family. (712 aa)
AFUA_3G14380Endosomal sorting complex protein TSG101, putative. (579 aa)
mvp1Sorting nexin mvp1; Required for vacuolar protein sorting. (729 aa)
AFUA_2G16730Peroxisome biosynthesis protein (PAS10/Peroxin-12), putative. (486 aa)
AFUA_2G16670Uncharacterized protein. (742 aa)
pfa3Palmitoyltransferase pfa3; Palmitoyltransferase specific for VAC8. Palmitoylates VAC8 at one or more of its N-terminal cysteine residues, which is required for its proper membrane localization (By similarity). (548 aa)
AFUA_2G16090Importin subunit alpha; Belongs to the importin alpha family. (552 aa)
AFUA_2G15870Importin beta-5 subunit, putative. (1042 aa)
AFUA_2G15820SNARE complex subunit (Syn8), putative. (339 aa)
AFUA_2G15570RAS small monomeric GTPase Rab6, putative. (207 aa)
AFUA_2G14760BCS1-like ATPase, putative; Belongs to the AAA ATPase family. (574 aa)
AFUA_2G14190Mitochondrial import inner membrane translocase subunit TIM23, putative. (212 aa)
AFUA_2G13750Vacuolar sorting protein, putative; Belongs to the STXBP/unc-18/SEC1 family. (666 aa)
AFUA_2G13040GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. (250 aa)
sec31Protein transport protein sec31; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity). (1263 aa)
AFUA_2G12870Vesicular-fusion protein sec17. (292 aa)
AFUA_2G12580Translocation protein Sec62, putative. (401 aa)
tim13Mitochondrial import inner membrane translocase subunit tim13; Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIM8- TIM13 complex is non essential and only mediates [...] (113 aa)
bro1Vacuolar protein-sorting protein bro1; Involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles; Belongs to the BRO1 family. (976 aa)
AFUA_2G10980ADP-ribosylation factor, putative; Belongs to the small GTPase superfamily. Arf family. (182 aa)
AFUA_2G10610Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (855 aa)
AFUA_2G10340AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (718 aa)
AFUA_2G10150Peroxisome biosynthesis protein (PAS1/Peroxin-1), putative. (1211 aa)
AFUA_2G10010Nonsense-mediated mRNA decay protein (Nmd5), putative. (1048 aa)
tim21Mitochondrial import inner membrane translocase subunit tim21; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Required to keep the TOM and the TIM23 complexes in close contact. At some point, it is released from the TOM23 complex to allow protein translocation into the mitochondrial matrix (By similarity). (237 aa)
AFUA_2G09290Antigenic mitochondrial protein HSP60, putative; Belongs to the chaperonin (HSP60) family. (587 aa)
AFUA_2G09180Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. (201 aa)
AFUA_2G08850Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1357 aa)
AFUA_2G07600SRP receptor beta subunit (Srp102), putative. (352 aa)
Your Current Organism:
Aspergillus fumigatus
NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293
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