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AFUA_6G04740 AFUA_6G04740 AFUA_5G01860 AFUA_5G01860 AFUA_5G02360 AFUA_5G02360 pan1 pan1 AFUA_2G05740 AFUA_2G05740 AFUA_2G04110 AFUA_2G04110 AFUA_2G03790 AFUA_2G03790 AFUA_2G03650 AFUA_2G03650 AFUA_2G02530 AFUA_2G02530 AFUA_2G01200 AFUA_2G01200 AFUA_1G06030 AFUA_1G06030 AFUA_1G02670 AFUA_1G02670 AFUA_1G02540 AFUA_1G02540 AFUA_6G12570 AFUA_6G12570 AFUA_6G12370 AFUA_6G12370 AFUA_6G09080 AFUA_6G09080 AFUA_6G08320 AFUA_6G08320 creD creD AFUA_6G07830 AFUA_6G07830 AFUA_6G07520 AFUA_6G07520 AFUA_6G06870 AFUA_6G06870 AFUA_6G06390 AFUA_6G06390 AFUA_4G07700 AFUA_4G07700 AFUA_4G08040 AFUA_4G08040 AFUA_4G09120 AFUA_4G09120 AFUA_4G10020 AFUA_4G10020 AFUA_4G12070 AFUA_4G12070 AFUA_4G13490 AFUA_4G13490 AFUA_1G15890 AFUA_1G15890 aps2 aps2 end3 end3 AFUA_1G12020 AFUA_1G12020 AFUA_1G11770 AFUA_1G11770 AFUA_1G11690 AFUA_1G11690 AFUA_5G05950 AFUA_5G05950 AFUA_5G06340 AFUA_5G06340 AFUA_5G06550 AFUA_5G06550 AFUA_5G07930 AFUA_5G07930 AFUA_5G08670 AFUA_5G08670 AFUA_5G09630 AFUA_5G09630 AFUA_5G10710 AFUA_5G10710 irs4 irs4 AFUA_5G12530 AFUA_5G12530 AFUA_3G05320 AFUA_3G05320 AFUA_3G05820 AFUA_3G05820 AFUA_3G05880 AFUA_3G05880 AFUA_3G06140 AFUA_3G06140 AFUA_3G10740 AFUA_3G10740 AFUA_3G12360 AFUA_3G12360 AFUA_3G12370 AFUA_3G12370 AFUA_3G14230 AFUA_3G14230 AFUA_2G10980 AFUA_2G10980 AFUA_2G08850 AFUA_2G08850 AFUA_2G11475 AFUA_2G11475 AFUA_2G11470 AFUA_2G11470 AFUA_1G12050 AFUA_1G12050 AFUA_1G13030 AFUA_1G13030 AFUA_4G04310 AFUA_4G04310 AFUA_7G02050 AFUA_7G02050 AFUA_7G02480 AFUA_7G02480 myoA myoA AFUA_8G04520 AFUA_8G04520 AFUA_6G03950 AFUA_6G03950 AFUA_6G04080 AFUA_6G04080
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AFUA_6G04740Actin Act1. (393 aa)
AFUA_5G01860Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (188 aa)
AFUA_5G02360Vacuolar dynamin-like GTPase VpsA, putative; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (698 aa)
pan1Actin cytoskeleton-regulatory complex protein pan1; Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity). (1467 aa)
AFUA_2G05740Rho GTPase ModA, putative. (192 aa)
AFUA_2G04110ENTH domain protein. (609 aa)
AFUA_2G03790Oxysterol binding protein (Osh7), putative; Belongs to the OSBP family. (491 aa)
AFUA_2G03650Golgi to endosome transport protein (Ent3), putative. (550 aa)
AFUA_2G02530Casein kinase I, putative; Belongs to the protein kinase superfamily. (383 aa)
AFUA_2G01200Actin polymerization protein Bzz1, putative. (743 aa)
AFUA_1G06030AP-1 complex subunit gamma. (803 aa)
AFUA_1G02670Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (320 aa)
AFUA_1G02540EF hand domain protein. (1258 aa)
AFUA_6G12570EH domain binding protein epsin 2. (561 aa)
AFUA_6G12370DUF2013 domain-containing protein. (783 aa)
AFUA_6G09080VHS domain protein. (436 aa)
AFUA_6G08320Uncharacterized protein. (470 aa)
creDProbable HECT-type ubiquitin ligase-interacting protein creD; Component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB. May be involved in signaling by recognizing appropriately phosphorylated substrates via its arrestin domains and then recruit a HECT-type ubiquitin ligase such as hulA, leading to ubiquitination of the substrate, providing a link between ubiquitination and phosphorylation in protein regulation and stability (By similarity). (601 aa)
AFUA_6G07830Stromal membrane-associated protein. (604 aa)
AFUA_6G07520Cell wall integrity signaling protein Lsp1/Pil1, putative. (349 aa)
AFUA_6G06870Casein kinase I homolog, putative. (523 aa)
AFUA_6G06390Uncharacterized protein. (62 aa)
AFUA_4G07700Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1693 aa)
AFUA_4G08040RAB GTPase Ypt5, putative. (218 aa)
AFUA_4G09120GTPase activating protein for Arf, putative. (652 aa)
AFUA_4G10020Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (242 aa)
AFUA_4G12070Endosomal peripheral membrane protein (Mon2), putative. (1688 aa)
AFUA_4G13490AP-3 adaptor complex subunit mu, putative; Belongs to the adaptor complexes medium subunit family. (624 aa)
AFUA_1G15890SacI domain protein. (937 aa)
aps2AP-2 complex subunit sigma; Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration (By similarity). (145 aa)
end3Actin cytoskeleton-regulatory complex protein end3; Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity). (404 aa)
AFUA_1G12020Arrestin domain protein. (814 aa)
AFUA_1G11770COPII-coated vesicle protein SurF4/Erv29, putative. (303 aa)
AFUA_1G11690Proline-rich, actin-associated protein Vrp1, putative. (455 aa)
AFUA_5G05950BAR adaptor protein RVS161, putative. (261 aa)
AFUA_5G06340BAR domain protein. (458 aa)
AFUA_5G06550Filamentation protein (Rhf1), putative. (1156 aa)
AFUA_5G07930AP-2 adaptor complex subunit mu, putative; Belongs to the adaptor complexes medium subunit family. (445 aa)
AFUA_5G08670Phosphatidylinositol 3-kinase VPS34. (898 aa)
AFUA_5G09630UBA/TS-N domain protein. (902 aa)
AFUA_5G10710Uncharacterized protein. (442 aa)
irs4Increased rDNA silencing protein 4; Positive regulator of phosphatidylinositol 4,5-bisphosphate turnover and negatively regulates signaling through the cell integrity pathway. Involved in rDNA silencing (By similarity). (513 aa)
AFUA_5G12530Arrestin (Or S-antigen), N-terminal domain protein. (525 aa)
AFUA_3G05320C2H2 finger domain protein, putative. (419 aa)
AFUA_3G05820ZZ type zinc finger domain protein. (838 aa)
AFUA_3G05880Oxysterol binding protein (Osh3), putative. (965 aa)
AFUA_3G06140Cytoskeleton assembly control protein Sla2, putative. (1043 aa)
AFUA_3G10740RAB GTPase Vps21/Ypt51, putative. (262 aa)
AFUA_3G12360Uncharacterized protein. (514 aa)
AFUA_3G12370V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (161 aa)
AFUA_3G14230BAR adaptor protein RVS167, putative. (406 aa)
AFUA_2G10980ADP-ribosylation factor, putative; Belongs to the small GTPase superfamily. Arf family. (182 aa)
AFUA_2G08850Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1357 aa)
AFUA_2G11475BAR domain protein. (305 aa)
AFUA_2G11470Uncharacterized protein. (419 aa)
AFUA_1G12050Acetyltransferase, GNAT family family. (293 aa)
AFUA_1G13030Uncharacterized protein. (672 aa)
AFUA_4G04310AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (939 aa)
AFUA_7G02050Arrestin (Or S-antigen), N-terminal domain protein. (603 aa)
AFUA_7G02480Oxysterol binding protein (Osh1), putative; Belongs to the OSBP family. (1184 aa)
myoAMyosin-1; Type-I myosin implicated in the organization of the actin cytoskeleton. Required for proper actin cytoskeleton polarization. At the cell cortex, assembles in patch-like structures together with proteins from the actin-polymerizing machinery and promotes actin assembly. Functions as actin nucleation-promoting factor (NPF) for the Arp2/3 complex. Plays an important role in polarized growth, spore germination, hyphal morphogenesis, and septal wall formation (By similarity). (1249 aa)
AFUA_8G04520Cytoskeleton assembly control protein Sla1, putative. (1168 aa)
AFUA_6G03950Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1277 aa)
AFUA_6G04080Uncharacterized protein. (2080 aa)
Your Current Organism:
Aspergillus fumigatus
NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293
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