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AFUA_8G01830 AFUA_8G01830 AFUA_1G12790 AFUA_1G12790 AFUA_1G11450 AFUA_1G11450 AFUA_1G13720 AFUA_1G13720 AFUA_4G04630 AFUA_4G04630 AFUA_4G04370 AFUA_4G04370 AFUA_4G04000 AFUA_4G04000 AFUA_4G03330 AFUA_4G03330 AFUA_4G03180 AFUA_4G03180 AFUA_4G02970 AFUA_4G02970 AFUA_4G02920 AFUA_4G02920 AFUA_7G01840 AFUA_7G01840 AFUA_8G02170 AFUA_8G02170 AFUA_8G05350 AFUA_8G05350 sec16 sec16 AFUA_6G04150 AFUA_6G04150 AFUA_6G05050 AFUA_6G05050 AFUA_5G01460 AFUA_5G01460 AFUA_5G03610 AFUA_5G03610 AFUA_5G04050 AFUA_5G04050 AFUA_5G04280 AFUA_5G04280 AFUA_7G05940 AFUA_7G05940 AFUA_2G00130 AFUA_2G00130 AFUA_1G07680 AFUA_1G07680 AFUA_1G06630 AFUA_1G06630 AFUA_1G06510 AFUA_1G06510 AFUA_1G06420 AFUA_1G06420 sar1 sar1 AFUA_1G04930 AFUA_1G04930 AFUA_1G03910 AFUA_1G03910 AFUA_6G13670 AFUA_6G13670 AFUA_6G12450 AFUA_6G12450 atg9 atg9 AFUA_6G11030 AFUA_6G11030 AFUA_6G10410 AFUA_6G10410 AFUA_6G08620 AFUA_6G08620 AFUA_6G06950 AFUA_6G06950 get1 get1 AFUA_4G06950 AFUA_4G06950 AFUA_4G07620 AFUA_4G07620 AFUA_4G10710 AFUA_4G10710 AFUA_4G11110 AFUA_4G11110 prm1 prm1 erv25 erv25 AFUA_1G17370 AFUA_1G17370 AFUA_1G15570 AFUA_1G15570 AFUA_1G11770 AFUA_1G11770 AFUA_1G11470 AFUA_1G11470 AFUA_1G10690 AFUA_1G10690 AFUA_1G09460 AFUA_1G09460 AFUA_1G09070 AFUA_1G09070 AFUA_1G09040 AFUA_1G09040 AFUA_1G08970 AFUA_1G08970 AFUA_1G08830 AFUA_1G08830 AFUA_5G05950 AFUA_5G05950 yop1 yop1 AFUA_5G06450 AFUA_5G06450 AFUA_5G08440 AFUA_5G08440 AFUA_5G13410 AFUA_5G13410 AFUA_3G07590 AFUA_3G07590 AFUA_3G08690 AFUA_3G08690 AFUA_3G08790 AFUA_3G08790 AFUA_3G09360 AFUA_3G09360 AFUA_3G10170 AFUA_3G10170 AFUA_3G10590 AFUA_3G10590 AFUA_3G11090 AFUA_3G11090 get3 get3 AFUA_3G12520 AFUA_3G12520 AFUA_3G14230 AFUA_3G14230 AFUA_2G16800 AFUA_2G16800 AFUA_2G16430 AFUA_2G16430 AFUA_2G13370 AFUA_2G13370 sec31 sec31 AFUA_2G12180 AFUA_2G12180 AFUA_2G11480 AFUA_2G11480 atg15 atg15 AFUA_2G09530 AFUA_2G09530 AFUA_2G09470 AFUA_2G09470 sey1 sey1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AFUA_8G01830Zn(2)-C6 fungal-type domain-containing protein. (497 aa)
AFUA_1G12790Exocyst complex component SEC5; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (1035 aa)
AFUA_1G11450Myosin class II heavy chain (MHC), putative. (2081 aa)
AFUA_1G13720Intracellular protein transport protein (UsoA), putative. (1061 aa)
AFUA_4G04630Golgi membrane protein, putative. (317 aa)
AFUA_4G04370Uncharacterized protein. (629 aa)
AFUA_4G04000LysM domain protein, putative. (652 aa)
AFUA_4G03330Plasma membrane stress response protein (Ist2), putative. (729 aa)
AFUA_4G03180Nuclear envelope protein Brr6, putative. (458 aa)
AFUA_4G02970Plasma membrane channel protein (Aqy1), putative. (735 aa)
AFUA_4G02920Zinc_ribbon_10 domain-containing protein. (402 aa)
AFUA_7G01840Membrane bound C2 domain protein (Vp115), putative. (1538 aa)
AFUA_8G02170C6 finger domain protein, putative. (462 aa)
AFUA_8G05350ER membrane protein complex subunit 3; The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER). Belongs to the EMC3 family. (268 aa)
sec16COPII coat assembly protein sec16; Involved in the initiation of assembly of the COPII coat required for the formation of transport vesicles from the endoplasmic reticulum (ER) and the selection of cargo molecules. Also involved in autophagy (By similarity); Belongs to the SEC16 family. (1832 aa)
AFUA_6G04150Protein transport protein sec22; Belongs to the synaptobrevin family. (215 aa)
AFUA_6G05050DUF410 domain protein. (346 aa)
AFUA_5G01460C6 finger domain protein, putative. (480 aa)
AFUA_5G03610Cdc48-dependent protein degradation adaptor protein (Shp1), putative. (394 aa)
AFUA_5G04050Scramblase family protein. (541 aa)
AFUA_5G04280DUF2012 domain-containing protein. (245 aa)
AFUA_7G05940Uncharacterized protein. (242 aa)
AFUA_2G00130Solid-state culture specific protein, putative. (463 aa)
AFUA_1G07680Secretion related GTPase SrgD. (231 aa)
AFUA_1G06630Golgi phosphoprotein 3 (GPP34) domain containing protein. (353 aa)
AFUA_1G06510Uncharacterized protein. (280 aa)
AFUA_1G06420SNF7 family protein. (241 aa)
sar1Small COPII coat GTPase sar1; Small GTPase component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. Sar1 controls the coat assembly in a stepwise manner. Activated Sar1-GTP binds to membranes first and recruits the sec23/24 complex. These sec23/24-sar1 prebudding intermediates are then collected by the Sec13/31 complex as subunits polymerize to form coated trans [...] (189 aa)
AFUA_1G04930Uncharacterized protein. (711 aa)
AFUA_1G03910Spo7-like protein. (467 aa)
AFUA_6G13670Reticulon-like protein. (270 aa)
AFUA_6G12450Chaperone/heat shock protein Hsp12, putative. (99 aa)
atg9Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Required for mitophagy. Cycles between the PAS and the cytoplasmic vesicle pool and may participate in supplying membrane for the growing autophagosome. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. Different machinerie [...] (951 aa)
AFUA_6G11030RNA binding protein MSSP-2, putative. (624 aa)
AFUA_6G10410E3 ubiquitin-protein ligase PEP5. (958 aa)
AFUA_6G08620Golgi reassembly stacking protein, putative. (370 aa)
AFUA_6G06950Ima1_N domain-containing protein. (854 aa)
get1Protein get1; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble get3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. (200 aa)
AFUA_4G06950Integral ER membrane protein Scs2, putative. (328 aa)
AFUA_4G07620Uncharacterized protein. (828 aa)
AFUA_4G10710Vesicle transport v-snare protein, putative. (224 aa)
AFUA_4G11110C2 domain protein. (1242 aa)
prm1Plasma membrane fusion protein prm1; Involved in cell fusion during mating by stabilizing the plasma membrane fusion event; Belongs to the PRM1 family. (740 aa)
erv25Endoplasmic reticulum vesicle protein 25; Constituent of COPII-coated endoplasmic reticulum-derived transport vesicles. Required for efficient transport of a subset of secretory proteins to the Golgi. Facilitates retrograde transport from the Golgi to the endoplasmic reticulum (By similarity); Belongs to the EMP24/GP25L family. (266 aa)
AFUA_1G17370Heat shock protein Awh11, putative. (81 aa)
AFUA_1G15570Ubiquitin-conjugating enzyme, putative. (287 aa)
AFUA_1G11770COPII-coated vesicle protein SurF4/Erv29, putative. (303 aa)
AFUA_1G11470Endosomal cargo receptor (P24), putative. (218 aa)
AFUA_1G10690M protein repeat protein. (878 aa)
AFUA_1G09460NIF domain protein. (518 aa)
AFUA_1G09070Uncharacterized protein. (1087 aa)
AFUA_1G09040Intermediate filament protein (Mdm1), putative. (1274 aa)
AFUA_1G08970Uncharacterized protein. (441 aa)
AFUA_1G08830Golgi matrix protein, putative. (527 aa)
AFUA_5G05950BAR adaptor protein RVS161, putative. (261 aa)
yop1Protein yop1; Involved in membrane/vesicle trafficking; Belongs to the DP1 family. (169 aa)
AFUA_5G06450Vacuolar protein sorting protein DigA. (961 aa)
AFUA_5G08440Uncharacterized protein. (286 aa)
AFUA_5G13410SNF7 family protein. (224 aa)
AFUA_3G07590ER-Golgi SNARE complex subunit (Sed5), putative. (346 aa)
AFUA_3G08690Uncharacterized protein. (212 aa)
AFUA_3G08790Uncharacterized protein. (294 aa)
AFUA_3G09360Vacuolar sorting ATPase Vps4, putative; Belongs to the AAA ATPase family. (435 aa)
AFUA_3G10170Uncharacterized protein. (1022 aa)
AFUA_3G10590Uncharacterized protein. (137 aa)
AFUA_3G11090Golgi complex component Cog3, putative. (756 aa)
get3ATPase get3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...] (340 aa)
AFUA_3G12520KxDL domain-containing protein. (153 aa)
AFUA_3G14230BAR adaptor protein RVS167, putative. (406 aa)
AFUA_2G16800Lectin family integral membrane protein, putative. (328 aa)
AFUA_2G16430Uncharacterized protein. (200 aa)
AFUA_2G13370Phosphatidylinositol 4-kinase type II subunit alpha, putative. (766 aa)
sec31Protein transport protein sec31; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity). (1263 aa)
AFUA_2G12180Lectin family integral membrane protein, putative. (327 aa)
AFUA_2G11480Uncharacterized protein. (444 aa)
atg15Putative lipase atg15; Lipase which is essential for lysis of subvacuolar cytoplasm to vacuole targeted bodies and intravacuolar autophagic bodies. Involved in the lysis of intravacuolar multivesicular body (MVB) vesicles. The intravacuolar membrane disintegration by atg15 is critical to life span extension (By similarity); Belongs to the AB hydrolase superfamily. Lipase family. (650 aa)
AFUA_2G09530DUF833 domain protein. (307 aa)
AFUA_2G09470Protein YOP1. (328 aa)
sey1Protein sey1; Cooperates with the reticulon proteins and tubule-shaping DP1 family proteins to generate and maintain the structure of the tubular endoplasmic reticulum network. Has GTPase activity, which is required for its function in ER organization; Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3-type GTPase family. RHD3 subfamily. (864 aa)
Your Current Organism:
Aspergillus fumigatus
NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293
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