STRINGSTRING
crzA crzA AFUA_2G07460 AFUA_2G07460 AFUA_2G07470 AFUA_2G07470 AFUA_2G07530 AFUA_2G07530 AFUA_2G09230 AFUA_2G09230 AFUA_2G09890 AFUA_2G09890 AFUA_2G10640 AFUA_2G10640 AFUA_2G11190 AFUA_2G11190 AFUA_2G11840 AFUA_2G11840 AFUA_2G12130 AFUA_2G12130 AFUA_2G12310 AFUA_2G12310 AFUA_2G12600 AFUA_2G12600 ptaB ptaB AFUA_2G13230 AFUA_2G13230 AFUA_2G13380 AFUA_2G13380 AFUA_2G14250 AFUA_2G14250 AFUA_2G14800 AFUA_2G14800 xlnR xlnR AFUA_2G15680 AFUA_2G15680 ssn8 ssn8 AFUA_3G14960 AFUA_3G14960 AFUA_3G14880 AFUA_3G14880 AFUA_3G14840 AFUA_3G14840 AFUA_3G14570 AFUA_3G14570 guf1 guf1 AFUA_3G13920 AFUA_3G13920 pacC pacC AFUA_3G11960 AFUA_3G11960 AFUA_3G11560 AFUA_3G11560 AFUA_3G11390 AFUA_3G11390 AFUA_3G11250 AFUA_3G11250 AFUA_3G11210 AFUA_3G11210 AFUA_3G11170 AFUA_3G11170 mbf1 mbf1 AFUA_3G08520 AFUA_3G08520 AFUA_3G08050 AFUA_3G08050 AFUA_3G08040 AFUA_3G08040 AFUA_3G06970 AFUA_3G06970 AFUA_3G06870 AFUA_3G06870 AFUA_3G06480 AFUA_3G06480 spt6 spt6 dhh1 dhh1 AFUA_3G05400 AFUA_3G05400 AFUA_5G14620 AFUA_5G14620 AFUA_5G13310 AFUA_5G13310 AFUA_5G12930 AFUA_5G12930 AFUA_5G11460 AFUA_5G11460 sreA sreA AFUA_5G11170 AFUA_5G11170 AFUA_5G11070 AFUA_5G11070 AFUA_5G10310 AFUA_5G10310 AFUA_5G09080 AFUA_5G09080 AFUA_5G08850 AFUA_5G08850 AFUA_5G08830 AFUA_5G08830 AFUA_5G08020 AFUA_5G08020 AFUA_5G07510 AFUA_5G07510 AFUA_5G07500 AFUA_5G07500 spt4 spt4 AFUA_5G06330 AFUA_5G06330 ino80 ino80 AFUA_5G05600 AFUA_5G05600 bur1 bur1 AFUA_1G09180 AFUA_1G09180 AFUA_1G09210 AFUA_1G09210 AFUA_1G09230 AFUA_1G09230 AFUA_1G09670 AFUA_1G09670 AFUA_1G10080 AFUA_1G10080 AFUA_1G10310 AFUA_1G10310 AFUA_1G10450 AFUA_1G10450 AFUA_1G10580 AFUA_1G10580 AFUA_1G10690 AFUA_1G10690 AFUA_1G10740 AFUA_1G10740 AFUA_1G11620 AFUA_1G11620 AFUA_1G12870 AFUA_1G12870 AFUA_1G13290 AFUA_1G13290 AFUA_1G14600 AFUA_1G14600 AFUA_1G15390 AFUA_1G15390 AFUA_1G15430 AFUA_1G15430 AFUA_1G15470 AFUA_1G15470 AFUA_1G15510 AFUA_1G15510 AFUA_1G16460 AFUA_1G16460 AFUA_1G16580 AFUA_1G16580 AFUA_1G17350 AFUA_1G17350 tpcE tpcE AFUA_4G14220 AFUA_4G14220 AFUA_4G13460 AFUA_4G13460 AFUA_4G13130 AFUA_4G13130 ccr4 ccr4 AFUA_4G12410 AFUA_4G12410 AFUA_4G12400 AFUA_4G12400 AFUA_4G12390 AFUA_4G12390 AFUA_4G11380 AFUA_4G11380 AFUA_4G10960 AFUA_4G10960 AFUA_4G10910 AFUA_4G10910 AFUA_4G10650 AFUA_4G10650 prtT prtT nosA nosA AFUA_4G09120 AFUA_4G09120 AFUA_4G08980 AFUA_4G08980 AFUA_4G08910 AFUA_4G08910 AFUA_4G08850 AFUA_4G08850 AFUA_4G08600 AFUA_4G08600 AFUA_4G07580 AFUA_4G07580 sec13 sec13 AFUA_6G06780 AFUA_6G06780 AFUA_6G07010 AFUA_6G07010 AFUA_6G07170 AFUA_6G07170 AFUA_6G07530 AFUA_6G07530 gliZ gliZ AFUA_6G09910 AFUA_6G09910 AFUA_6G11170 AFUA_6G11170 AFUA_6G11430 AFUA_6G11430 AFUA_6G11460 AFUA_6G11460 AFUA_6G12090 AFUA_6G12090 utp10 utp10 AFUA_6G14150 AFUA_6G14150 AFUA_1G00580 AFUA_1G00580 AFUA_1G03210 AFUA_1G03210 AFUA_1G03380 AFUA_1G03380 AFUA_1G03770 AFUA_1G03770 AFUA_1G03780 AFUA_1G03780 AFUA_1G03840 AFUA_1G03840 AFUA_1G04070 AFUA_1G04070 AFUA_1G04590 AFUA_1G04590 AFUA_1G04900 AFUA_1G04900 AFUA_1G04910 AFUA_1G04910 AFUA_1G05370 AFUA_1G05370 nut2 nut2 AFUA_1G06170 AFUA_1G06170 AFUA_1G06980 AFUA_1G06980 AFUA_1G07020 AFUA_1G07020 AFUA_1G07150 AFUA_1G07150 AFUA_1G07630 AFUA_1G07630 spt16 spt16 AFUA_2G00720 AFUA_2G00720 AFUA_2G00750 AFUA_2G00750 AFUA_2G01780 AFUA_2G01780 AFUA_2G01900 AFUA_2G01900 cgi121 cgi121 esa1 esa1 AFUA_2G05770 AFUA_2G05770 AFUA_2G06060 AFUA_2G06060 AFUA_7G06550 AFUA_7G06550 AFUA_7G05620 AFUA_7G05620 AFUA_7G05510 AFUA_7G05510 pob3 pob3 AFUA_7G04270 AFUA_7G04270 AFUA_7G03780 AFUA_7G03780 AFUA_7G03720 AFUA_7G03720 AFUA_3G02340 AFUA_3G02340 AFUA_3G04070 AFUA_3G04070 AFUA_3G04230 AFUA_3G04230 AFUA_5G04190 AFUA_5G04190 AFUA_5G04020 AFUA_5G04020 hapX hapX AFUA_5G03770 AFUA_5G03770 AFUA_5G03680 AFUA_5G03680 AFUA_5G03660 AFUA_5G03660 AFUA_5G03160 AFUA_5G03160 AFUA_5G01980 AFUA_5G01980 htz1 htz1 AFUA_5G01010 AFUA_5G01010 AFUA_5G00700 AFUA_5G00700 AFUA_6G05300 AFUA_6G05300 AFUA_6G05160 AFUA_6G05160 AFUA_6G05150 AFUA_6G05150 rai1 rai1 med6 med6 kae1 kae1 cdc123 cdc123 AFUA_6G02850 AFUA_6G02850 AFUA_6G02480 AFUA_6G02480 AFUA_6G02200 AFUA_6G02200 AFUA_6G02190 AFUA_6G02190 AFUA_6G02110 AFUA_6G02110 AFUA_6G01960 AFUA_6G01960 AFUA_8G03920 AFUA_8G03920 AFUA_8G04050 AFUA_8G04050 AFUA_8G04270 AFUA_8G04270 AFUA_8G05270 AFUA_8G05270 AFUA_8G05300 AFUA_8G05300 AFUA_8G05680 AFUA_8G05680 AFUA_8G02710 AFUA_8G02710 AFUA_8G02310 AFUA_8G02310 AFUA_8G02160 AFUA_8G02160 AFUA_7G02610 AFUA_7G02610 somA somA AFUA_7G02190 AFUA_7G02190 AFUA_7G02100 AFUA_7G02100 AFUA_7G01340 AFUA_7G01340 AFUA_7G01000 AFUA_7G01000 AFUA_4G02830 AFUA_4G02830 kapC kapC AFUA_4G03020 AFUA_4G03020 AFUA_4G04290 AFUA_4G04290 AFUA_4G04660 AFUA_4G04660 AFUA_1G13760 AFUA_1G13760 AFUA_1G12550 AFUA_1G12550 AFUA_4G12470 AFUA_4G12470 AFUA_8G00342 AFUA_8G00342 AFUA_2G04262 AFUA_2G04262 AFUA_6G12522 AFUA_6G12522 AFUA_1G12875 AFUA_1G12875 AFUA_1G12332 AFUA_1G12332 sin4 sin4
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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co-expression
protein homology
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crzAC2H2 finger domain transcription factor crzA; Transcription factor involved in the regulation of calcium ion homeostasis. Regulates genes encoding calcium transporters, transcription factors and genes that could be directly or indirectly involved in calcium metabolism. Supports especially pmcA, pmcB and pmcC expression encoding for calcium- translocating P-type ATPases. Binds target promoters at motif A[GT][CG]CA[AC][AG]. Plays an essential role germination, radial growth, and asexual development. Plays also a major role in proper chitin and glucan incorporation into the cell wall. Inv [...] (754 aa)
AFUA_2G07460RNA polymerase II transcriptional coactivator, putative. (165 aa)
AFUA_2G07470MIT domain-containing protein. (1178 aa)
AFUA_2G07530Uncharacterized protein. (144 aa)
AFUA_2G09230ATP-dependent RNA helicase (Hrh1), putative. (821 aa)
AFUA_2G09890NDT80 / PhoG like DNA-binding family protein. (605 aa)
AFUA_2G10640Transcriptional adapter 2; Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and ADA. SAGA is involved in RNA polymerase II-dependent transcriptional regulation. (508 aa)
AFUA_2G11190Pol II transcription elongation factor subunit Cdc73, putative. (471 aa)
AFUA_2G11840Transcriptional corepressor Cyc8, putative. (867 aa)
AFUA_2G12130CID domain-containing protein. (239 aa)
AFUA_2G12310HLH transcription factor, putative. (420 aa)
AFUA_2G12600Uncharacterized protein. (699 aa)
ptaBTranscriptional activator ptaB; Transcriptional regulator that forms a complex with somA to control biofilm formation; Belongs to the MFG1 family. (729 aa)
AFUA_2G13230Universal stress protein family domain protein. (710 aa)
AFUA_2G13380GATA transcription factor (AreB), putative. (318 aa)
AFUA_2G14250CBF/NF-Y family transcription factor, putative. (247 aa)
AFUA_2G14800HLH transcription factor (Hpa3), putative. (525 aa)
xlnRXylanolytic transcriptional activator xlnR; Transcriptional activator of the xylanolytic system. Involved in the regulation of extracellular cellulolytic and xylanolytic genes and in the regulation of the intracellular activities of D-xylose catabolic genes in the pentose catabolic pathway (PCP) in response to the presence of D-xylose (By similarity); Belongs to the xlnR/xlr1 family. (954 aa)
AFUA_2G15680Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (111 aa)
ssn8RNA polymerase II holoenzyme cyclin-like subunit; Component of the srb8-11 complex. The srb8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The srb8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex. The srb8-11 complex phosphorylates the C-terminal domain (CTD) of the largest subunit of RNA polymerase II (By s [...] (302 aa)
AFUA_3G14960Lipase/esterase, putative. (359 aa)
AFUA_3G14880Oxidoreductase, 2OG-Fe(II) oxygenase family, putative; Belongs to the iron/ascorbate-dependent oxidoreductase family. (368 aa)
AFUA_3G14840C6 transcription factor, putative. (646 aa)
AFUA_3G14570Histidine acid phosphatase, putative; Belongs to the histidine acid phosphatase family. (462 aa)
guf1Translation factor guf1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. (683 aa)
AFUA_3G13920APSES transcription factor, putative. (668 aa)
pacCpH-response transcription factor pacC/RIM101; Transcription factor that mediates regulation of both acid- and alkaline-expressed genes in response to ambient pH. At alkaline ambient pH, activates transcription of alkaline-expressed genes (including pacC itself) and represses transcription of acid- expressed genes (By similarity). (676 aa)
AFUA_3G11960Forkhead transcription factor Fkh1/2, putative. (722 aa)
AFUA_3G11560Lipase/esterase, putative. (487 aa)
AFUA_3G11390Proteasome regulatory particle subunit Rpt3, putative; Belongs to the AAA ATPase family. (465 aa)
AFUA_3G11250C2H2 transcription factor (Swi5), putative. (772 aa)
AFUA_3G11210YagE family protein. (424 aa)
AFUA_3G11170CP2 transcription factor, putative. (759 aa)
mbf1Multiprotein-bridging factor 1; Transcriptional coactivator that stimulates transcriptional activity by bridging regulatory proteins and TBP, thereby recruiting TBP to promoters occupied by DNA-binding regulators. (154 aa)
AFUA_3G08520SRF-type transcription factor RlmA. (600 aa)
AFUA_3G08050C6 transcription factor (OTam), putative. (738 aa)
AFUA_3G08040Polymerase (RNA) II (DNA directed) polypeptide D. (148 aa)
AFUA_3G0697040S ribosomal protein S9. (237 aa)
AFUA_3G06870MYB DNA-binding domain protein. (662 aa)
AFUA_3G06480Histone-lysine N-methyltransferase (Ash1), putative. (845 aa)
spt6Transcription elongation factor spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression (By similarity); Belongs to the SPT6 family. (1420 aa)
dhh1ATP-dependent RNA helicase dhh1; ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping. Is involved in G1/S DNA-damage checkpoint recovery, probably through the regulation of the translational status of a subset of mRNAs. May also have a role in translation and mRNA nuclear export (By similarity); Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily. (507 aa)
AFUA_3G05400DnaJ and TPR domain protein. (522 aa)
AFUA_5G14620Uncharacterized protein. (195 aa)
AFUA_5G13310C6 transcription factor, putative. (1027 aa)
AFUA_5G12930C6 finger domain protein, putative. (664 aa)
AFUA_5G11460Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...] (284 aa)
sreAGATA-type transcription factor sreA; GATA-type transcription repressor that regulates iron- acquisition genes through specific binding the GATA sequence element 5'-ATCWGATAA-3' of target promoters. Iron acquisition regulation is critical for survival under both iron- limiting conditions (to acquire essential iron) and iron-replete conditions (to limit iron toxicity). SreA targets include genes encoding a number of key iron-regulated factors such as those involved in siderophore biosynthesis. (546 aa)
AFUA_5G11170Nucleosome remodeling complex ATPase subunit (Snf2h), putative. (986 aa)
AFUA_5G11070C6 transcription factor (ArcA), putative. (702 aa)
AFUA_5G10310AflR-like C6 zinc cluster transcription factor, putative. (475 aa)
AFUA_5G09080Transcription factor (SPT8), putative. (612 aa)
AFUA_5G08850Uncharacterized protein. (564 aa)
AFUA_5G08830Woronin body protein HexA, putative. (537 aa)
AFUA_5G08020HLH DNA binding protein (Penr2), putative. (139 aa)
AFUA_5G07510C6 transcription factor AlcR. (866 aa)
AFUA_5G07500Beta-lactamase family protein. (358 aa)
spt4Transcription elongation factor spt4; The spt4-spt5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene (By similarity). (156 aa)
AFUA_5G06330RSC complex subunit (Sth1), putative. (1406 aa)
ino80Chromatin-remodeling ATPase INO80; ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair. (1708 aa)
AFUA_5G05600Forkhead transcription factor (Sep1), putative. (724 aa)
bur1Serine/threonine-protein kinase bur1; Serine/threonine-protein kinase involved in transcription regulation. Phosphorylates the UBC2/RAD6 ubiquitin-conjugating enzyme (E2), leading to monoubiquitination of histone H2B and the silencing of telomeric-associated genes. Also required for histone H3 methylation. Necessary for the recovery from pheromone-induced growth arrest in the cell cycle G1 phase (By similarity). (580 aa)
AFUA_1G09180Uncharacterized protein. (470 aa)
AFUA_1G09210AAA family ATPase/60S ribosome export protein Rix7, putative. (784 aa)
AFUA_1G09230DUF1000 domain protein. (181 aa)
AFUA_1G09670HLH transcription factor (GlcD gamma), putative. (502 aa)
AFUA_1G10080C2H2 transcription factor, putative. (570 aa)
AFUA_1G10310RNase L inhibitor of the ABC superfamily, putative. (703 aa)
AFUA_1G10450Uncharacterized protein. (845 aa)
AFUA_1G10580Homeobox transcription factor, putative. (697 aa)
AFUA_1G10690M protein repeat protein. (878 aa)
AFUA_1G10740Prefoldin subunit 5, putative. (119 aa)
AFUA_1G11620C6 transcription factor QutA, putative. (905 aa)
AFUA_1G12870Uncharacterized protein. (490 aa)
AFUA_1G13290SAGA complex component (Sgf29), putative. (469 aa)
AFUA_1G14600Transcription initiation factor TFIID, 31kD subunit, putative. (306 aa)
AFUA_1G15390DUF1014 domain protein. (222 aa)
AFUA_1G15430Lipase/esterase, putative. (330 aa)
AFUA_1G15470C6 transcription factor (UaY), putative. (1088 aa)
AFUA_1G15510JmjC domain protein, putative. (571 aa)
AFUA_1G16460BZIP transcription factor (LziP), putative. (651 aa)
AFUA_1G16580Uncharacterized protein. (948 aa)
AFUA_1G17350CP2 transcription factor, putative. (639 aa)
tpcETrypacidin cluster transcription factor; Transcription factor that regulates the expression of the gene clusters that mediate the biosynthesis of trypacidin, a metabolite with antiprotozoal activity and a possible role in the infection process. Trypacidin is toxic for human pulmonary and bronchial epithelial cells by initiating the intracellular formation of nitric oxide (NO) and hydrogen peroxide (H(2)O(2)), thus triggering host necrotic cell death. (396 aa)
AFUA_4G14220C6 finger domain protein, putative. (715 aa)
AFUA_4G13460SNF2 family helicase/ATPase, putative. (1111 aa)
AFUA_4G13130Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (769 aa)
ccr4Glucose-repressible alcohol dehydrogenase transcriptional effector; Acts as catalytic component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover. Ccr4 has 3'-5' RNase activity with a strong preference for polyadenylated substrates and also low exonuclease activity towards single-stranded DNA. Discovered because of its role in the control of ADH2 gene expression. It is required for the expression of genes involved in non-fermentative growth (By similarity); Belongs to [...] (696 aa)
AFUA_4G12410HMG box protein, putative. (507 aa)
AFUA_4G12400PHD finger domain protein, putative. (836 aa)
AFUA_4G12390Cell differentiation protein (Rcd1), putative. (394 aa)
AFUA_4G11380Uncharacterized protein. (92 aa)
AFUA_4G10960Uncharacterized protein. (194 aa)
AFUA_4G10910Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (1058 aa)
AFUA_4G10650Uncharacterized protein. (198 aa)
prtTTranscriptional activator of proteases prtT; Transcription factor required for protein utilization and degradation. Regulates transcription of major secreted proteases including a serine alkaline protease (alk1), a metalloprotease (mep), an aspergillopepsin (pep1), a sedolisin (sed2) and two dipeptidyl- peptidases (dppIV and dppV). However, it is not a virulence determinant in leukopenic mice; Belongs to the prtT family. (696 aa)
nosAC6 finger domain transcription factor nosA; Transcription factor that mediates stress and developmental response. (685 aa)
AFUA_4G09120GTPase activating protein for Arf, putative. (652 aa)
AFUA_4G08980Uncharacterized protein. (203 aa)
AFUA_4G08910DUF3835 domain-containing protein. (592 aa)
AFUA_4G08850Uncharacterized protein. (402 aa)
AFUA_4G08600Aldehyde dehydrogenase, putative; Belongs to the aldehyde dehydrogenase family. (550 aa)
AFUA_4G07580Translation initiation factor EF-2 gamma subunit, putative. (516 aa)
sec13Protein transport protein sec13; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. It also functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport facto [...] (306 aa)
AFUA_6G06780Proteasome regulatory particle subunit Rpt4, putative; Belongs to the AAA ATPase family. (393 aa)
AFUA_6G07010C6 transcription factor RosA. (662 aa)
AFUA_6G07170Uncharacterized protein. (212 aa)
AFUA_6G07530BZIP transcription factor, putative. (280 aa)
gliZC6 finger domain transcription factor gliZ; Transcription factor that regulates gliotoxin production and contributes to virulence. (489 aa)
AFUA_6G09910Glutaminase, putative. (721 aa)
AFUA_6G11170C2H2 finger domain protein (Ezf), putative. (381 aa)
AFUA_6G11430Aldehyde dehydrogenase AldA, putative; Belongs to the aldehyde dehydrogenase family. (559 aa)
AFUA_6G11460Nonsense-mediated mRNA decay protein Upf3, putative. (581 aa)
AFUA_6G12090HET domain protein. (618 aa)
utp10U3 small nucleolar RNA-associated protein 10; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity). (1798 aa)
AFUA_6G14150C6 transcription factor, putative. (389 aa)
AFUA_1G00580Transcriptional regulator PacG/VIB-1. (529 aa)
AFUA_1G03210MYB family conidiophore development protein FlbD, putative. (314 aa)
AFUA_1G03380UDP-N-acetylglucosaminyltransferase. (1634 aa)
AFUA_1G03770Uncharacterized protein. (309 aa)
AFUA_1G03780C6 finger domain protein, putative. (351 aa)
AFUA_1G03840CCAAT-binding factor complex subunit HapC. (223 aa)
AFUA_1G04070Eukaryotic translation initiation factor eIF-5A. (192 aa)
AFUA_1G04590Transcriptional regulator Ngg1, putative. (675 aa)
AFUA_1G04900Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (219 aa)
AFUA_1G04910Vezatin domain-containing protein. (629 aa)
AFUA_1G05370Uncharacterized protein. (374 aa)
nut2Mediator of RNA polymerase II transcription subunit 10; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (159 aa)
AFUA_1G06170Proteasome regulatory particle subunit Rpt5, putative; Belongs to the AAA ATPase family. (464 aa)
AFUA_1G0698030S ribosomal subunit S4, putative. (469 aa)
AFUA_1G07020Cyclin, putative; Belongs to the cyclin family. (438 aa)
AFUA_1G07150RING finger domain protein (Rnf10), putative. (751 aa)
AFUA_1G07630Zinc knuckle domain protein (Byr3), putative. (190 aa)
spt16FACT complex subunit spt16; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (1019 aa)
AFUA_2G00720Aldehyde dehydrogenase, putative. (492 aa)
AFUA_2G00750Oxidoreductase, 2OG-Fe(II) oxygenase family, putative; Belongs to the iron/ascorbate-dependent oxidoreductase family. (364 aa)
AFUA_2G01780Small nucleolar ribonucleoprotein complex subunit Utp15, putative. (542 aa)
AFUA_2G01900RNA polymerase II transcription elongation factor Rtf1p, putative. (607 aa)
cgi121EKC/KEOPS complex subunit cgi121; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Cgi121 acts as an allosteric effector that regulates the t(6)A activity of the complex. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transc [...] (189 aa)
esa1Histone acetyltransferase esa1; Catalytic component of the NuA4 histone acetyltransferase (HAT) complex which is involved in epigenetic transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4, H3, H2B, H2A and H2A variant H2A.Z. Acetylates histone H4 to form H4K5ac, H4K8ac, H4K12ac and H4K16ac, histone H3 to form H3K14ac, histone H2B to form H2BK16ac, and histone H2A to form H2AK4ac and H2AK7ac. Acetylation of histone H4 is essential for DNA double- strand break repair through homologous recombination. Involved in cell cycle progression. Recru [...] (483 aa)
AFUA_2G05770SAGA complex component (Sgf73), putative. (412 aa)
AFUA_2G06060Transcriptional co-activator (Hfi1/Ada1), putative. (419 aa)
AFUA_7G06550Fungal specific transcription factor, putative. (607 aa)
AFUA_7G05620APSES transcription factor (MbpA), putative. (884 aa)
AFUA_7G05510RSC complex subunit (RSC8), putative. (732 aa)
pob3FACT complex subunit pob3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (573 aa)
AFUA_7G042703'-5' exonuclease/helicase (Wrn), putative. (419 aa)
AFUA_7G03780YT521-B-like splicing factor, putative. (546 aa)
AFUA_7G03720Serine/threonine protein kinase (Kin28), putative; Belongs to the protein kinase superfamily. (404 aa)
AFUA_3G02340CBF/NF-Y family transcription factor, putative. (142 aa)
AFUA_3G04070BZIP transcription factor HacA. (433 aa)
AFUA_3G04230Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (667 aa)
AFUA_5G04190HLH transcription factor (PalcA), putative. (742 aa)
AFUA_5G04020DNA damage repair protein (Rad9), putative. (1338 aa)
hapXbZIP transcription factor hapX; Transcription factor required for repression of genes during iron starvation. Represses iron-dependent and mitochondrial-localized activities including respiration, TCA cycle, amino acid metabolism, iron-sulfur-cluster and heme biosynthesis. Iron starvation causes a massive remodeling of the amino acid pool and hapX is essential for the coordination of the production of siderophores and their precursor ornithine ; Belongs to the bZIP family. YAP subfamily. (491 aa)
AFUA_5G03770Lipase, putative. (340 aa)
AFUA_5G03680Transcription initiation factor TFIID complex 60 kDa subunit. (445 aa)
AFUA_5G03660Transcription initiation factor TFIID subunit beta, putative. (401 aa)
AFUA_5G03160Protein kinase, putative. (1092 aa)
AFUA_5G01980Histone deacetylase HdaA. (602 aa)
htz1Histone H2A.Z; Variant histone H2A which can replace H2A in some nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. This variant is enriched at promoters, it may keep them in a repressed state until the appropriate activa [...] (138 aa)
AFUA_5G01010Uncharacterized protein. (312 aa)
AFUA_5G00700Uncharacterized protein. (221 aa)
AFUA_6G05300CCAAT-binding factor complex subunit HapE. (271 aa)
AFUA_6G05160C2H2 transcription factor (Azf1), putative. (444 aa)
AFUA_6G05150Transcriptional repressor TupA/RocA, putative. (702 aa)
rai1Decapping nuclease rai1; Ribonuclease that specifically degrades pre-mRNAs with a defective 5' end cap and is part of a pre-mRNA capping quality control. Has decapping and pyrophosphohydrolase activities. Has decapping activity toward incomplete 5' end cap mRNAs such as unmethylated 5' end-capped RNA to release GpppN and 5' end monophosphate RNA. Also possesses RNA 5'-pyrophosphohydrolase activity by hydrolyzing the 5' end triphosphate to release pyrophosphates (By similarity). Belongs to the DXO/Dom3Z family. (365 aa)
med6Mediator of RNA polymerase II transcription subunit 6; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (324 aa)
kae1tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...] (352 aa)
cdc123Cell division cycle protein 123; Regulates the cell cycle in a nutrient dependent manner. Belongs to the CDC123 family. (417 aa)
AFUA_6G02850C6 finger domain protein, putative. (758 aa)
AFUA_6G02480Esterase, putative. (391 aa)
AFUA_6G02200C2HC5 finger protein. (537 aa)
AFUA_6G02190SAGA-associated factor 11; Functions as component of the transcription regulatory histone acetylation (HAT) complex SAGA. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac). SAGA interacts with DNA [...] (338 aa)
AFUA_6G02110MADS box transcription factor Mcm1. (219 aa)
AFUA_6G01960C6 finger domain protein, putative. (368 aa)
AFUA_8G03920Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (103 aa)
AFUA_8G04050Transcriptional regulator PacG/VIB-1. (583 aa)
AFUA_8G04270AAA family ATPase, putative. (1654 aa)
AFUA_8G05270C6 transcription factor, putative. (866 aa)
AFUA_8G05300RNA polymerase II subunit 7. (139 aa)
AFUA_8G05680Serine/threonine-protein kinase. (1119 aa)
AFUA_8G02710C6 transcription factor, putative. (887 aa)
AFUA_8G02310Aldehyde dehydrogenase ALDH; Belongs to the aldehyde dehydrogenase family. (568 aa)
AFUA_8G02160Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family. (510 aa)
AFUA_7G02610WD repeat protein. (629 aa)
somATranscriptional activator somA; Transcription factor that controls the expression of genes related to the process of conidiation and adherence and regulates biofilm formation. Controls conidiation and adhesion primarily by affecting the expression of the three regulatory genes flbB, stuA and medA. Required for virulence in an egg and a mouse infection model. Belongs to the FLO8 family. (784 aa)
AFUA_7G02190Zinc knuckle nucleic acid binding protein, putative. (233 aa)
AFUA_7G02100Uncharacterized protein. (262 aa)
AFUA_7G01340RPEL repeat protein. (145 aa)
AFUA_7G01000Aldehyde dehydrogenase, putative; Belongs to the aldehyde dehydrogenase family. (493 aa)
AFUA_4G02830Aldehyde dehydrogenase, putative; Belongs to the aldehyde dehydrogenase family. (484 aa)
kapCPutative transcription factor kapC; Putative transcription factor; Belongs to the bZIP family. (280 aa)
AFUA_4G03020Chromatin remodeling complex subunit (Arp5), putative; Belongs to the actin family. (757 aa)
AFUA_4G04290Histone deacetylase HosB. (1191 aa)
AFUA_4G04660Proteasome regulatory particle subunit Rpt6, putative; Belongs to the AAA ATPase family. (389 aa)
AFUA_1G13760Cell wall anchored protein, putative. (561 aa)
AFUA_1G12550Membrane-tethered transcription factor (SPT23), putative. (1407 aa)
AFUA_4G12470BZIP transcription factor CpcA. (252 aa)
AFUA_8G00342Uncharacterized protein. (310 aa)
AFUA_2G04262C6 transcription factor, putative. (748 aa)
AFUA_6G12522Stress response transcription factor SrrA/Skn7, putative. (622 aa)
AFUA_1G12875Uncharacterized protein. (271 aa)
AFUA_1G12332Jumonji family transcription factor, putative. (1432 aa)
sin4Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (955 aa)
Your Current Organism:
Aspergillus fumigatus
NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293
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