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vma21 vma21 AFUA_3G08840 AFUA_3G08840 AFUA_3G08970 AFUA_3G08970 AFUA_3G09700 AFUA_3G09700 sec31 sec31 AFUA_2G10610 AFUA_2G10610 AFUA_2G10340 AFUA_2G10340 AFUA_2G09830 AFUA_2G09830 AFUA_4G04310 AFUA_4G04310 sec16 sec16 AFUA_6G04150 AFUA_6G04150 AFUA_2G03650 AFUA_2G03650 AFUA_2G02560 AFUA_2G02560 AFUA_2G01570 AFUA_2G01570 AFUA_1G06030 AFUA_1G06030 sar1 sar1 AFUA_1G04930 AFUA_1G04930 AFUA_2G09180 AFUA_2G09180 AFUA_7G05735 AFUA_7G05735 AFUA_1G13720 AFUA_1G13720 sec23 sec23 AFUA_1G03180 AFUA_1G03180 sec24 sec24 AFUA_1G13260 AFUA_1G13260 sec13 sec13 AFUA_4G07700 AFUA_4G07700 AFUA_4G10020 AFUA_4G10020 AFUA_4G10200 AFUA_4G10200 AFUA_4G10710 AFUA_4G10710 AFUA_1G15860 AFUA_1G15860 AFUA_1G10970 AFUA_1G10970 aps2 aps2 AFUA_5G07930 AFUA_5G07930 AFUA_5G09660 AFUA_5G09660 AFUA_5G10730 AFUA_5G10730
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
vma21Vacuolar ATPase assembly integral membrane protein vma21; Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum; Belongs to the VMA21 family. (127 aa)
AFUA_3G08840Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. (1212 aa)
AFUA_3G08970AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (746 aa)
AFUA_3G09700Sec23/Sec24 family protein. (1019 aa)
sec31Protein transport protein sec31; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity). (1263 aa)
AFUA_2G10610Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (855 aa)
AFUA_2G10340AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (718 aa)
AFUA_2G09830ARF GTPase activator (Glo3), putative. (386 aa)
AFUA_4G04310AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (939 aa)
sec16COPII coat assembly protein sec16; Involved in the initiation of assembly of the COPII coat required for the formation of transport vesicles from the endoplasmic reticulum (ER) and the selection of cargo molecules. Also involved in autophagy (By similarity); Belongs to the SEC16 family. (1832 aa)
AFUA_6G04150Protein transport protein sec22; Belongs to the synaptobrevin family. (215 aa)
AFUA_2G03650Golgi to endosome transport protein (Ent3), putative. (550 aa)
AFUA_2G02560Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (916 aa)
AFUA_2G01570AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (148 aa)
AFUA_1G06030AP-1 complex subunit gamma. (803 aa)
sar1Small COPII coat GTPase sar1; Small GTPase component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. Sar1 controls the coat assembly in a stepwise manner. Activated Sar1-GTP binds to membranes first and recruits the sec23/24 complex. These sec23/24-sar1 prebudding intermediates are then collected by the Sec13/31 complex as subunits polymerize to form coated trans [...] (189 aa)
AFUA_1G04930Uncharacterized protein. (711 aa)
AFUA_2G09180Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. (201 aa)
AFUA_7G05735Protein transport protein BOS1; SNARE required for protein transport between the ER and the Golgi complex. (244 aa)
AFUA_1G13720Intracellular protein transport protein (UsoA), putative. (1061 aa)
sec23Protein transport protein sec23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity). (780 aa)
AFUA_1G03180DUF636 domain protein. (134 aa)
sec24Protein transport protein sec24; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity). (919 aa)
AFUA_1G13260Coatomer subunit epsilon; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Belongs to the COPE family. (269 aa)
sec13Protein transport protein sec13; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. It also functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport facto [...] (306 aa)
AFUA_4G07700Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1693 aa)
AFUA_4G10020Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (242 aa)
AFUA_4G10200Transcription factor RfeF, putative. (675 aa)
AFUA_4G10710Vesicle transport v-snare protein, putative. (224 aa)
AFUA_1G15860Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. (591 aa)
AFUA_1G10970Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (955 aa)
aps2AP-2 complex subunit sigma; Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration (By similarity). (145 aa)
AFUA_5G07930AP-2 adaptor complex subunit mu, putative; Belongs to the adaptor complexes medium subunit family. (445 aa)
AFUA_5G09660AP-1 adaptor complex subunit mu, putative; Belongs to the adaptor complexes medium subunit family. (446 aa)
AFUA_5G10730Rad60-SLD_2 domain-containing protein. (267 aa)
Your Current Organism:
Aspergillus fumigatus
NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293
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