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AFUA_2G12880 AFUA_2G12880 AFUA_2G12150 AFUA_2G12150 AFUA_2G11510 AFUA_2G11510 AFUA_1G13070 AFUA_1G13070 AFUA_2G17060 AFUA_2G17060 AFUA_1G14220 AFUA_1G14220 AFUA_7G01460 AFUA_7G01460 AFUA_7G02210 AFUA_7G02210 AFUA_7G02610 AFUA_7G02610 AFUA_8G05430 AFUA_8G05430 AFUA_8G04640 AFUA_8G04640 AFUA_8G04220 AFUA_8G04220 AFUA_6G04260 AFUA_6G04260 AFUA_6G04330 AFUA_6G04330 rrp36 rrp36 loc1 loc1 AFUA_5G03090 AFUA_5G03090 AFUA_5G03870 AFUA_5G03870 AFUA_5G04000 AFUA_5G04000 AFUA_3G04310 AFUA_3G04310 AFUA_3G04110 AFUA_3G04110 AFUA_7G04430 AFUA_7G04430 AFUA_7G04860 AFUA_7G04860 AFUA_7G05460 AFUA_7G05460 dbp3 dbp3 AFUA_2G05950 AFUA_2G05950 AFUA_2G05930 AFUA_2G05930 AFUA_2G04780 AFUA_2G04780 AFUA_2G03930 AFUA_2G03930 AFUA_2G03340 AFUA_2G03340 efg1 efg1 AFUA_2G08320 AFUA_2G08320 AFUA_2G01780 AFUA_2G01780 nop16 nop16 AFUA_1G06290 AFUA_1G06290 AFUA_1G06230 AFUA_1G06230 rrp3 rrp3 AFUA_1G05630 AFUA_1G05630 AFUA_1G05410 AFUA_1G05410 NAT10 NAT10 mrd1 mrd1 AFUA_1G04550 AFUA_1G04550 AFUA_1G04240 AFUA_1G04240 AFUA_1G02680 AFUA_1G02680 AFUA_1G02610 AFUA_1G02610 AFUA_1G02210 AFUA_1G02210 AFUA_1G02200 AFUA_1G02200 AFUA_6G14260 AFUA_6G14260 utp10 utp10 AFUA_6G12920 AFUA_6G12920 dbp4 dbp4 AFUA_6G08800 AFUA_6G08800 AFUA_6G08240 AFUA_6G08240 AFUA_4G05880 AFUA_4G05880 AFUA_4G06180 AFUA_4G06180 AFUA_4G07500 AFUA_4G07500 AFUA_4G07540 AFUA_4G07540 ytm1 ytm1 nop7 nop7 AFUA_4G08930 AFUA_4G08930 AFUA_1G16330 AFUA_1G16330 drs1 drs1 AFUA_1G14580 AFUA_1G14580 AFUA_1G11160 AFUA_1G11160 AFUA_1G10990 AFUA_1G10990 AFUA_1G10560 AFUA_1G10560 AFUA_1G10440 AFUA_1G10440 AFUA_1G09950 AFUA_1G09950 utp25 utp25 AFUA_1G09210 AFUA_1G09210 erb1 erb1 AFUA_5G05930 AFUA_5G05930 TIF6 TIF6 AFUA_5G06520 AFUA_5G06520 AFUA_5G11730 AFUA_5G11730 spb1 spb1 AFUA_5G12270 AFUA_5G12270 AFUA_5G12860 AFUA_5G12860 AFUA_3G05490 AFUA_3G05490 AFUA_3G05840 AFUA_3G05840 nsa2 nsa2 AFUA_3G09080 AFUA_3G09080 AFUA_3G09600 AFUA_3G09600 AFUA_3G09750 AFUA_3G09750 AFUA_2G11380 AFUA_2G11380 AFUA_3G10730 AFUA_3G10730 nop9 nop9 nop58 nop58 AFUA_3G13760 AFUA_3G13760 AFUA_2G17050 AFUA_2G17050 AFUA_2G16040 AFUA_2G16040 AFUA_2G13570 AFUA_2G13570 AFUA_2G12890 AFUA_2G12890
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AFUA_2G12880Pre-rRNA processing protein Tsr1, putative. (803 aa)
AFUA_2G12150Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family. (4925 aa)
AFUA_2G11510Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (650 aa)
AFUA_1G13070U3 small nucleolar ribonucleoprotein protein IMP4, putative. (299 aa)
AFUA_2G1706060S ribosome subunit biogenesis protein NIP7; Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (185 aa)
AFUA_1G14220Fibrillarin. (312 aa)
AFUA_7G01460Ribosomal protein S5; Belongs to the universal ribosomal protein uS5 family. (259 aa)
AFUA_7G02210Ribosomal small subunit assembly protein, putative. (315 aa)
AFUA_7G02610WD repeat protein. (629 aa)
AFUA_8G05430Ribosome biogenesis protein Noc4, putative. (569 aa)
AFUA_8G04640RNA-3'-phosphate cyclase family protein. (403 aa)
AFUA_8G04220rRNA maturation protein (Nop14), putative. (913 aa)
AFUA_6G04260Protein MAK16; Belongs to the MAK16 family. (324 aa)
AFUA_6G04330DEAH-box RNA helicase (Dhr1), putative. (1211 aa)
rrp36rRNA biogenesis protein rrp36; Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway (By similarity). (356 aa)
loc160S ribosomal subunit assembly/export protein loc1; Required for efficient assembly and nuclear export of the 60S ribosomal subunit. (190 aa)
AFUA_5G03090Small nucleolar ribonucleoprotein complex subunit (Pwp2), putative. (926 aa)
AFUA_5G03870DUF1665 domain protein. (300 aa)
AFUA_5G0400020S-pre-rRNA D-site endonuclease NOB1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. Belongs to the NOB1 family. (435 aa)
AFUA_3G04310SnoRNA binding protein, putative. (856 aa)
AFUA_3G04110rRNA processing protein Bystin, putative. (497 aa)
AFUA_7G04430Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (220 aa)
AFUA_7G04860rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (392 aa)
AFUA_7G05460Uncharacterized protein. (404 aa)
dbp3ATP-dependent RNA helicase dbp3; ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5.8S rRNAs (By similarity); Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily. (503 aa)
AFUA_2G05950Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (126 aa)
AFUA_2G05930Small nucleolar ribonucleoprotein complex subunit, putative. (618 aa)
AFUA_2G04780WD repeat protein. (721 aa)
AFUA_2G03930Small nucleolar ribonucleoprotein complex subunit, putative. (976 aa)
AFUA_2G03340DUF652 domain protein. (192 aa)
efg1rRNA-processing protein efg1; Involved in rRNA processing; Belongs to the EFG1 family. (319 aa)
AFUA_2G08320U3 small nucleolar ribonucleoprotein subunit (Imp3), putative. (188 aa)
AFUA_2G01780Small nucleolar ribonucleoprotein complex subunit Utp15, putative. (542 aa)
nop16Nucleolar protein 16; Involved in the biogenesis of the 60S ribosomal subunit. (241 aa)
AFUA_1G06290Small nucleolar ribonucleoprotein complex subunit (SOF1), putative. (476 aa)
AFUA_1G06230Ribosome biogenesis protein Ssf2, putative. (445 aa)
rrp3ATP-dependent rRNA helicase rrp3; ATP-dependent rRNA helicase required for pre-ribosomal RNA processing. Involved in the maturation of the 35S-pre-rRNA and to its cleavage to mature 18S rRNA. (472 aa)
AFUA_1G0563040S ribosomal protein S3, putative; Belongs to the universal ribosomal protein uS3 family. (266 aa)
AFUA_1G05410Ribosome biogenesis protein Kri1. (617 aa)
NAT10RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1066 aa)
mrd1Multiple RNA-binding domain-containing protein 1; Involved in pre-rRNA processing; Belongs to the RRM MRD1 family. (825 aa)
AFUA_1G04550HMG box protein, putative. (309 aa)
AFUA_1G04240Small nucleolar ribonucleoprotein complex subunit Utp14, putatrive. (960 aa)
AFUA_1G02680Small nucleolar ribonucleoprotein complex subunit Dip2, putative. (1000 aa)
AFUA_1G02610rRNA processing protein, putative. (325 aa)
AFUA_1G0221060S ribosome biogenesis protein Brx1, putative. (376 aa)
AFUA_1G02200F-box domain protein. (357 aa)
AFUA_6G14260U3 small nucleolar ribonucleoprotein protein Lcp5, putative. (395 aa)
utp10U3 small nucleolar RNA-associated protein 10; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity). (1798 aa)
AFUA_6G12920C2H2 finger domain protein, putative. (161 aa)
dbp4ATP-dependent RNA helicase dbp4; ATP-dependent RNA helicase required for ribosome biogenesis. Involved in the release of U14 snoRNA in pre-ribosomal complexes. Required for pre-rRNA cleavage at site A2 (By similarity). (787 aa)
AFUA_6G08800Cellular morphogenesis protein (Bud22), putative. (448 aa)
AFUA_6G08240HEAT repeat protein (DRIM), putative. (2582 aa)
AFUA_4G05880U3 small nucleolar ribonucleoprotein protein MPP10; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the MPP10 family. (717 aa)
AFUA_4G06180Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (364 aa)
AFUA_4G07500Small nucleolar ribonucleoprotein complex subunit, putative. (656 aa)
AFUA_4G07540Small nucleolar ribonucleoprotein complex subunit, putative. (966 aa)
ytm1Ribosome biogenesis protein ytm1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (488 aa)
nop7Pescadillo homolog; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (675 aa)
AFUA_4G08930Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (560 aa)
AFUA_1G16330Ribosome assembly protein Noc2, putative. (788 aa)
drs1ATP-dependent RNA helicase drs1; ATP-binding RNA helicase involved in ribosome assembly. (830 aa)
AFUA_1G14580U3 small nucleolar RNA-associated protein 11; Involved in nucleolar processing of pre-18S ribosomal RNA. (294 aa)
AFUA_1G11160Sas10/Utp3 family protein. (662 aa)
AFUA_1G10990Ribosomal RNA processing protein, putative. (325 aa)
AFUA_1G10560GTP binding protein, putative. (462 aa)
AFUA_1G10440PUM-HD domain-containing protein. (698 aa)
AFUA_1G09950Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (294 aa)
utp25U3 small nucleolar RNA-associated protein 25; DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2. (671 aa)
AFUA_1G09210AAA family ATPase/60S ribosome export protein Rix7, putative. (784 aa)
erb1Ribosome biogenesis protein erb1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (795 aa)
AFUA_5G05930RNA processing factor 1. (425 aa)
TIF6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family. (247 aa)
AFUA_5G06520Low-temperature viability protein ltv1. (490 aa)
AFUA_5G11730RIO1 family protein kinase, putative. (412 aa)
spb1AdoMet-dependent rRNA methyltransferase spb1; Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. (795 aa)
AFUA_5G12270rRNA processing protein (Ebp2), putative. (384 aa)
AFUA_5G12860Uncharacterized protein. (392 aa)
AFUA_3G05490U3 small nucleolar RNA-associated protein 22. (1117 aa)
AFUA_3G05840RNA binding protein Rnp24, putative. (372 aa)
nsa2Ribosome biogenesis protein nsa2; Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles (By similarity). (283 aa)
AFUA_3G09080HAD_SAK_1 domain-containing protein. (564 aa)
AFUA_3G09600Pre-rRNA processing nucleolar protein Sik1, putative. (522 aa)
AFUA_3G09750rRNA processing protein Utp6, putative. (332 aa)
AFUA_2G11380KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. (358 aa)
AFUA_3G1073040S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (201 aa)
nop9Nucleolar protein 9; RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit (By similarity); Belongs to the NOP9 family. (699 aa)
nop58Nucleolar protein 58; Required for pre-18S rRNA processing. May bind microtubules (By similarity); Belongs to the NOP5/NOP56 family. (591 aa)
AFUA_3G13760AB hydrolase-1 domain-containing protein. (387 aa)
AFUA_2G17050Nucleolar complex-associated protein 3; Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm. Belongs to the CBF/MAK21 family. (692 aa)
AFUA_2G16040rRNA biogenesis protein RRP5, putative. (1822 aa)
AFUA_2G13570Ribosome biogenesis protein (Bms1), putative. (1182 aa)
AFUA_2G12890Small nucleolar ribonucleoprotein complex subunit, putative. (535 aa)
Your Current Organism:
Aspergillus fumigatus
NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293
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