STRINGSTRING
pan1 pan1 AFUA_6G04940 AFUA_6G04940 AFUA_6G04740 AFUA_6G04740 AFUA_6G02370 AFUA_6G02370 AFUA_6G02360 AFUA_6G02360 AFUA_8G04520 AFUA_8G04520 AFUA_4G03050 AFUA_4G03050 AFUA_4G04180 AFUA_4G04180 AFUA_1G13330 AFUA_1G13330 AFUA_3G14230 AFUA_3G14230 AFUA_3G12250 AFUA_3G12250 AFUA_3G10700 AFUA_3G10700 AFUA_3G10250 AFUA_3G10250 AFUA_3G06140 AFUA_3G06140 AFUA_5G14060 AFUA_5G14060 AFUA_5G12150 AFUA_5G12150 AFUA_5G11560 AFUA_5G11560 AFUA_5G08700 AFUA_5G08700 AFUA_5G08300 AFUA_5G08300 AFUA_5G05860 AFUA_5G05860 end3 end3 AFUA_1G13590 AFUA_1G13590 AFUA_4G12270 AFUA_4G12270 AFUA_4G07700 AFUA_4G07700 AFUA_6G06500 AFUA_6G06500 AFUA_6G12370 AFUA_6G12370 AFUA_1G02670 AFUA_1G02670 cap2 cap2 AFUA_1G05930 AFUA_1G05930 AFUA_7G05950 AFUA_7G05950 AFUA_7G04210 AFUA_7G04210 AFUA_5G01860 AFUA_5G01860
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pan1Actin cytoskeleton-regulatory complex protein pan1; Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity). (1467 aa)
AFUA_6G04940Cytokinesis protein SepA/Bni1. (1800 aa)
AFUA_6G04740Actin Act1. (393 aa)
AFUA_6G02370Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (169 aa)
AFUA_6G02360Uncharacterized protein. (624 aa)
AFUA_8G04520Cytoskeleton assembly control protein Sla1, putative. (1168 aa)
AFUA_4G03050Profilin; Belongs to the profilin family. (136 aa)
AFUA_4G04180Chitin synthase B. (1084 aa)
AFUA_1G13330Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (388 aa)
AFUA_3G14230BAR adaptor protein RVS167, putative. (406 aa)
AFUA_3G12250Protein-tyrosine phosphatase, putative. (613 aa)
AFUA_3G10700Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (193 aa)
AFUA_3G10250Cell division control protein (Cdc15), putative. (944 aa)
AFUA_3G06140Cytoskeleton assembly control protein Sla2, putative. (1043 aa)
AFUA_5G14060Rho GTPase Rho4, putative. (286 aa)
AFUA_5G12150PH domain protein. (408 aa)
AFUA_5G11560Arp2/3 complex subunit (Arp3), putative; Belongs to the actin family. (439 aa)
AFUA_5G08700Myosin type II heavy chain, putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2405 aa)
AFUA_5G08300Alpha-actinin, sarcomeric (F-actin cross linking protein). (645 aa)
AFUA_5G05860CRIB domain-containing protein. (815 aa)
end3Actin cytoskeleton-regulatory complex protein end3; Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity). (404 aa)
AFUA_1G13590MHD domain-containing protein. (701 aa)
AFUA_4G12270LIM domain protein. (806 aa)
AFUA_4G07700Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1693 aa)
AFUA_6G06500Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family. (363 aa)
AFUA_6G12370DUF2013 domain-containing protein. (783 aa)
AFUA_1G02670Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (320 aa)
cap2F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity). (322 aa)
AFUA_1G05930Serine/threonine protein kinase, putative. (998 aa)
AFUA_7G05950Cytokinesis EF-hand protein Cdc4, putative. (167 aa)
AFUA_7G04210Tropomyosin, putative. (154 aa)
AFUA_5G01860Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (188 aa)
Your Current Organism:
Aspergillus fumigatus
NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293
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