STRINGSTRING
AFUA_1G15100 AFUA_1G15100 AFUA_8G05170 AFUA_8G05170 AFUA_8G04900 AFUA_8G04900 AFUA_8G04520 AFUA_8G04520 AFUA_6G02510 AFUA_6G02510 AFUA_6G02870 AFUA_6G02870 AFUA_6G02920 AFUA_6G02920 AFUA_6G03840 AFUA_6G03840 AFUA_6G03950 AFUA_6G03950 sec16 sec16 AFUA_6G03990 AFUA_6G03990 AFUA_6G04080 AFUA_6G04080 AFUA_6G04150 AFUA_6G04150 AFUA_6G04220 AFUA_6G04220 AFUA_6G04760 AFUA_6G04760 AFUA_6G04770 AFUA_6G04770 AFUA_6G04780 AFUA_6G04780 AFUA_6G04840 AFUA_6G04840 AFUA_6G05220 AFUA_6G05220 AFUA_5G02360 AFUA_5G02360 AFUA_5G02510 AFUA_5G02510 AFUA_5G02900 AFUA_5G02900 AFUA_5G03510 AFUA_5G03510 AFUA_3G04060 AFUA_3G04060 mirB mirB AFUA_3G02360 AFUA_3G02360 AFUA_3G02050 AFUA_3G02050 AFUA_3G00820 AFUA_3G00820 AFUA_3G00810 AFUA_3G00810 AFUA_7G03640 AFUA_7G03640 AFUA_2G10860 AFUA_2G10860 AFUA_2G16692 AFUA_2G16692 AFUA_7G05735 AFUA_7G05735 AFUA_7G01620 AFUA_7G01620 AFUA_6G11200 AFUA_6G11200 arp2 arp2 AFUA_6G06900 AFUA_6G06900 AFUA_1G13030 AFUA_1G13030 AFUA_1G13720 AFUA_1G13720 AFUA_3G06690 AFUA_3G06690 AFUA_6G11190 AFUA_6G11190 arp1 arp1 AFUA_4G04630 AFUA_4G04630 AFUA_4G04310 AFUA_4G04310 AFUA_4G04100 AFUA_4G04100 AFUA_4G03870 AFUA_4G03870 AFUA_4G03040 AFUA_4G03040 AFUA_7G00700 AFUA_7G00700 AFUA_7G02270 AFUA_7G02270 AFUA_8G05630 AFUA_8G05630 pan1 pan1 AFUA_7G04950 AFUA_7G04950 AFUA_7G05580 AFUA_7G05580 AFUA_7G05700 AFUA_7G05700 sit1 sit1 AFUA_2G05020 AFUA_2G05020 mon1 mon1 vps27 vps27 AFUA_2G04720 AFUA_2G04720 hse1 hse1 AFUA_2G04210 AFUA_2G04210 AFUA_2G04110 AFUA_2G04110 AFUA_2G03650 AFUA_2G03650 AFUA_2G02840 AFUA_2G02840 AFUA_2G02610 AFUA_2G02610 AFUA_2G02560 AFUA_2G02560 AFUA_2G01570 AFUA_2G01570 AFUA_2G01530 AFUA_2G01530 AFUA_1G07680 AFUA_1G07680 atg8 atg8 AFUA_1G07420 AFUA_1G07420 AFUA_1G07010 AFUA_1G07010 AFUA_1G06420 AFUA_1G06420 AFUA_1G06030 AFUA_1G06030 AFUA_1G05730 AFUA_1G05730 AFUA_1G05280 AFUA_1G05280 AFUA_1G05120 AFUA_1G05120 AFUA_1G05100 AFUA_1G05100 sar1 sar1 AFUA_1G04930 AFUA_1G04930 AFUA_1G04080 AFUA_1G04080 AFUA_1G03460 AFUA_1G03460 AFUA_1G03450 AFUA_1G03450 sec23 sec23 AFUA_1G03180 AFUA_1G03180 AFUA_1G02850 AFUA_1G02850 AFUA_1G02540 AFUA_1G02540 AFUA_1G02320 AFUA_1G02320 AFUA_1G02310 AFUA_1G02310 AFUA_1G02190 AFUA_1G02190 AFUA_6G14530 AFUA_6G14530 AFUA_6G14170 AFUA_6G14170 AFUA_6G13020 AFUA_6G13020 AFUA_6G12890 AFUA_6G12890 sec24 sec24 AFUA_6G12570 AFUA_6G12570 atg9 atg9 fmqA fmqA fmqE fmqE exo84 exo84 AFUA_6G10410 AFUA_6G10410 AFUA_6G08290 AFUA_6G08290 AFUA_6G07930 AFUA_6G07930 AFUA_6G07560 AFUA_6G07560 AFUA_6G07490 AFUA_6G07490 AFUA_6G07440 AFUA_6G07440 AFUA_6G07290 AFUA_6G07290 AFUA_6G06910 AFUA_6G06910 AFUA_6G06390 AFUA_6G06390 sec13 sec13 AFUA_4G06400 AFUA_4G06400 AFUA_4G06480 AFUA_4G06480 AFUA_4G07070 AFUA_4G07070 AFUA_4G07700 AFUA_4G07700 AFUA_4G08040 AFUA_4G08040 AFUA_4G08470 AFUA_4G08470 AFUA_4G10020 AFUA_4G10020 AFUA_4G10040 AFUA_4G10040 AFUA_4G10200 AFUA_4G10200 AFUA_4G10210 AFUA_4G10210 AFUA_4G10600 AFUA_4G10600 AFUA_4G10710 AFUA_4G10710 AFUA_4G11000 AFUA_4G11000 AFUA_4G11560 AFUA_4G11560 AFUA_4G11590 AFUA_4G11590 AFUA_4G11810 AFUA_4G11810 AFUA_4G12060 AFUA_4G12060 AFUA_4G12070 AFUA_4G12070 AFUA_4G12290 AFUA_4G12290 AFUA_4G12490 AFUA_4G12490 AFUA_4G12830 AFUA_4G12830 snx4 snx4 erv25 erv25 AFUA_4G13340 AFUA_4G13340 AFUA_4G13490 AFUA_4G13490 AFUA_4G14270 AFUA_4G14270 AFUA_1G16930 AFUA_1G16930 AFUA_1G16320 AFUA_1G16320 AFUA_1G15890 AFUA_1G15890 AFUA_1G15860 AFUA_1G15860 AFUA_1G15250 AFUA_1G15250 ssh4 ssh4 mns1B mns1B aps2 aps2 AFUA_1G13960 AFUA_1G13960 AFUA_1G13590 AFUA_1G13590 AFUA_1G13260 AFUA_1G13260 end3 end3 AFUA_1G12540 AFUA_1G12540 AFUA_1G11770 AFUA_1G11770 AFUA_1G11470 AFUA_1G11470 AFUA_1G10970 AFUA_1G10970 AFUA_1G10950 AFUA_1G10950 AFUA_1G10330 AFUA_1G10330 AFUA_1G09870 AFUA_1G09870 AFUA_1G09640 AFUA_1G09640 AFUA_1G09560 AFUA_1G09560 AFUA_1G09480 AFUA_1G09480 AFUA_1G09220 AFUA_1G09220 gmt1 gmt1 AFUA_5G05970 AFUA_5G05970 AFUA_5G06220 AFUA_5G06220 AFUA_5G06450 AFUA_5G06450 AFUA_5G06520 AFUA_5G06520 AFUA_5G07150 AFUA_5G07150 AFUA_5G07860 AFUA_5G07860 AFUA_5G07930 AFUA_5G07930 AFUA_5G08230 AFUA_5G08230 AFUA_5G08530 AFUA_5G08530 AFUA_5G08670 AFUA_5G08670 AFUA_5G09660 AFUA_5G09660 AFUA_5G10630 AFUA_5G10630 AFUA_5G10730 AFUA_5G10730 atg18 atg18 AFUA_5G12130 AFUA_5G12130 AFUA_5G12880 AFUA_5G12880 AFUA_5G13320 AFUA_5G13320 AFUA_5G13410 AFUA_5G13410 AFUA_5G13600 AFUA_5G13600 AFUA_5G13890 AFUA_5G13890 AFUA_5G14060 AFUA_5G14060 AFUA_5G14730 AFUA_5G14730 fleA fleA AFUA_3G05630 AFUA_3G05630 AFUA_3G06140 AFUA_3G06140 AFUA_3G06430 AFUA_3G06430 snx3 snx3 vma21 vma21 AFUA_3G08730 AFUA_3G08730 AFUA_3G08790 AFUA_3G08790 AFUA_3G08840 AFUA_3G08840 AFUA_3G08970 AFUA_3G08970 AFUA_3G09360 AFUA_3G09360 AFUA_3G09700 AFUA_3G09700 AFUA_3G10340 AFUA_3G10340 AFUA_3G10360 AFUA_3G10360 AFUA_3G10740 AFUA_3G10740 AFUA_3G11200 AFUA_3G11200 AFUA_3G12520 AFUA_3G12520 AFUA_3G12800 AFUA_3G12800 AFUA_3G13340 AFUA_3G13340 AFUA_3G13770 AFUA_3G13770 PSD2 PSD2 AFUA_3G14380 AFUA_3G14380 AFUA_2G17650 AFUA_2G17650 alb1 alb1 ayg1 ayg1 mvp1 mvp1 AFUA_2G16800 AFUA_2G16800 AFUA_2G16670 AFUA_2G16670 AFUA_2G16520 AFUA_2G16520 AFUA_2G16390 AFUA_2G16390 AFUA_2G15820 AFUA_2G15820 AFUA_2G15750 AFUA_2G15750 AFUA_2G15080 AFUA_2G15080 AFUA_2G14900 AFUA_2G14900 AFUA_2G14270 AFUA_2G14270 AFUA_2G14160 AFUA_2G14160 AFUA_2G13750 AFUA_2G13750 AFUA_2G13440 AFUA_2G13440 AFUA_2G13430 AFUA_2G13430 AFUA_2G13370 AFUA_2G13370 sec31 sec31 AFUA_2G12180 AFUA_2G12180 AFUA_2G12140 AFUA_2G12140 AFUA_2G12050 AFUA_2G12050 bro1 bro1 AFUA_2G10930 AFUA_2G10930 atg15 atg15 AFUA_2G10610 AFUA_2G10610 AFUA_2G10340 AFUA_2G10340 AFUA_2G09830 AFUA_2G09830 AFUA_2G09180 AFUA_2G09180 AFUA_2G08900 AFUA_2G08900 AFUA_2G08720 AFUA_2G08720 AFUA_2G08180 AFUA_2G08180 akr1 akr1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AFUA_1G15100EBP domain protein, putative. (276 aa)
AFUA_8G05170Autophagy protein Apg6, putative. (446 aa)
AFUA_8G04900Uncharacterized protein. (197 aa)
AFUA_8G04520Cytoskeleton assembly control protein Sla1, putative. (1168 aa)
AFUA_6G02510Chitin biosynthesis protein (Chs5), putative. (457 aa)
AFUA_6G02870Uncharacterized protein. (399 aa)
AFUA_6G02920SNARE protein Snc2, putative. (121 aa)
AFUA_6G03840ER to Golgi transport protein Yif1. (366 aa)
AFUA_6G03950Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1277 aa)
sec16COPII coat assembly protein sec16; Involved in the initiation of assembly of the COPII coat required for the formation of transport vesicles from the endoplasmic reticulum (ER) and the selection of cargo molecules. Also involved in autophagy (By similarity); Belongs to the SEC16 family. (1832 aa)
AFUA_6G03990GAS2 domain protein. (1494 aa)
AFUA_6G04080Uncharacterized protein. (2080 aa)
AFUA_6G04150Protein transport protein sec22; Belongs to the synaptobrevin family. (215 aa)
AFUA_6G04220DAO domain-containing protein. (386 aa)
AFUA_6G04760UPF0220 domain protein. (185 aa)
AFUA_6G04770Sld7_C domain-containing protein. (223 aa)
AFUA_6G04780Vacuolar protein sorting 55 superfamily. (128 aa)
AFUA_6G04840Hypercellular protein HypA. (1423 aa)
AFUA_6G05220BET3 family protein. (189 aa)
AFUA_5G02360Vacuolar dynamin-like GTPase VpsA, putative; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (698 aa)
AFUA_5G02510GARP complex component (Vps54), putative. (1091 aa)
AFUA_5G02900SNARE domain protein. (251 aa)
AFUA_5G03510PQ loop repeat protein. (194 aa)
AFUA_3G04060SNF7 family protein Fti1/Did2, putative. (209 aa)
mirBMFS siderochrome iron transporter B; Major facilitator transporter involved in triacetylfusarinine C (TAFC) uptake. Can also transport ferricrocin and coprogen, but not ferrichrysin. (612 aa)
AFUA_3G02360FAD dependent oxidoreductase superfamily. (438 aa)
AFUA_3G02050Uncharacterized protein. (171 aa)
AFUA_3G00820Putative exported protein. (415 aa)
AFUA_3G00810Cholestenol delta-isomerase, putative. (225 aa)
AFUA_7G03640AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane. (953 aa)
AFUA_2G10860RING finger protein. (842 aa)
AFUA_2G16692Vacuolar sorting protein SNF7 family protein, putative. (480 aa)
AFUA_7G05735Protein transport protein BOS1; SNARE required for protein transport between the ER and the Golgi complex. (244 aa)
AFUA_7G01620Uncharacterized protein. (566 aa)
AFUA_6G11200DENN (AEX-3) domain protein. (909 aa)
arp2Hydroxynaphthalene reductase arp2; Hydroxynaphthalene reductase; part of the gene cluster that mediates the biosynthesis of dihydroxynaphthalene (DHN)-melanin, a bluish-green pigment and a structural component of the conidial wall. The first step of the pathway is the production of the heptaketide naphtopyrone YWA1 by the polyketide synthase alb1 though condensation of acetyl-CoA with malonyl-CoA. The naphtopyrone YWA1 is then converted to the pentaketide 1,3,6,8-tetrahydroxynaphthalene (1,3,6,8-THN) by the heptaketide hydrolyase ayg1 though chain-length shortening. 1,3,6,8-THN is subs [...] (273 aa)
AFUA_6G06900Rho GTPase Rho1. (200 aa)
AFUA_1G13030Uncharacterized protein. (672 aa)
AFUA_1G13720Intracellular protein transport protein (UsoA), putative. (1061 aa)
AFUA_3G06690Rho GTPase Rho3. (197 aa)
AFUA_6G11190Protein kinase (VPS15), putative. (1637 aa)
arp1Scytalone dehydratase arp1; Scytalone dehydratase; part of the gene cluster that mediates the biosynthesis of dihydroxynaphthalene (DHN)-melanin, a bluish-green pigment and a structural component of the conidial wall. The first step of the pathway is the production of the heptaketide naphtopyrone YWA1 by the polyketide synthase alb1 though condensation of acetyl-CoA with malonyl-CoA. The naphtopyrone YWA1 is then converted to the pentaketide 1,3,6,8-tetrahydroxynaphthalene (1,3,6,8-THN) by the heptaketide hydrolyase ayg1 though chain-length shortening. 1,3,6,8-THN is substrate of the h [...] (168 aa)
AFUA_4G04630Golgi membrane protein, putative. (317 aa)
AFUA_4G04310AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (939 aa)
AFUA_4G04100Vacuolar protein sorting protein (Vps36), putative. (537 aa)
AFUA_4G03870Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (260 aa)
AFUA_4G03040Got1 family protein. (112 aa)
AFUA_7G00700Aldo-keto reductase (AKR13), puatative. (340 aa)
AFUA_7G02270Trafficking protein particle complex subunit BET3. (189 aa)
AFUA_8G05630Chitin synthase F. (1182 aa)
pan1Actin cytoskeleton-regulatory complex protein pan1; Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity). (1467 aa)
AFUA_7G04950Lipase, putative. (281 aa)
AFUA_7G05580Phospholipase. (879 aa)
AFUA_7G05700Guanyl-nucleotide exchange factor (Sec7), putative. (2004 aa)
sit1Siderophore iron transporter 1; Major facilitator transporter involved in ferrichrome (FC) and ferrioxamine B (FOB) uptake. (577 aa)
AFUA_2G05020Cellular morphogenesis regulator DopA. (1675 aa)
mon1Vacuolar fusion protein mon1; Required for multiple vacuole delivery pathways including the cytoplasm to vacuole transport (Cvt), autophagy, pexophagy and endocytosis; Belongs to the MON1/SAND family. (621 aa)
vps27Vacuolar protein sorting-associated protein 27; Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane. (729 aa)
AFUA_2G04720Ubiquitin C-terminal hydrolase, putative. (1108 aa)
hse1Class E vacuolar protein-sorting machinery protein hse1; Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB). (584 aa)
AFUA_2G04210Uncharacterized protein. (256 aa)
AFUA_2G04110ENTH domain protein. (609 aa)
AFUA_2G03650Golgi to endosome transport protein (Ent3), putative. (550 aa)
AFUA_2G02840TBC domain protein, putative. (640 aa)
AFUA_2G02610SNARE complex subunit (Vam7), putative. (383 aa)
AFUA_2G02560Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (916 aa)
AFUA_2G01570AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (148 aa)
AFUA_2G01530COPII-coated vesicle protein (Erv41), putative. (379 aa)
AFUA_1G07680Secretion related GTPase SrgD. (231 aa)
atg8Autophagy-related protein 8; Ubiquitin-like modifier involved in autophagosomes formation. With atg4, mediates the delivery of the autophagosomes to the vacuole via the microtubule cytoskeleton. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Participates also in membrane fusion events that take place in the early secretory pathway. Also involved [...] (118 aa)
AFUA_1G07420SNARE complex subunit (Bet1), putative. (169 aa)
AFUA_1G07010Phosphatidate cytidylyltransferase; Belongs to the CDS family. (432 aa)
AFUA_1G06420SNF7 family protein. (241 aa)
AFUA_1G06030AP-1 complex subunit gamma. (803 aa)
AFUA_1G05730Vacuolar sorting receptor (Mrl1), putative. (351 aa)
AFUA_1G05280Golgi complex component (Vps8), putative. (1588 aa)
AFUA_1G05120COPII-coated vesicle membrane protein Erv46, putative. (438 aa)
AFUA_1G05100GARP complex subunit Vps53, putative. (854 aa)
sar1Small COPII coat GTPase sar1; Small GTPase component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. Sar1 controls the coat assembly in a stepwise manner. Activated Sar1-GTP binds to membranes first and recruits the sec23/24 complex. These sec23/24-sar1 prebudding intermediates are then collected by the Sec13/31 complex as subunits polymerize to form coated trans [...] (189 aa)
AFUA_1G04930Uncharacterized protein. (711 aa)
AFUA_1G04080GARP complex subunit (Sac2), putative. (678 aa)
AFUA_1G03460Uncharacterized protein. (361 aa)
AFUA_1G03450Calpain-like protease PalBory; Belongs to the peptidase C2 family. (805 aa)
sec23Protein transport protein sec23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity). (780 aa)
AFUA_1G03180DUF636 domain protein. (134 aa)
AFUA_1G02850L-cystine transporter, putative. (265 aa)
AFUA_1G02540EF hand domain protein. (1258 aa)
AFUA_1G02320Uncharacterized protein. (229 aa)
AFUA_1G02310Uncharacterized protein. (225 aa)
AFUA_1G02190Ras GTPase Rab11, putative. (204 aa)
AFUA_6G14530L-cystine transporter, putative. (280 aa)
AFUA_6G14170CDF zinc transporter (Msc2), putaitve. (877 aa)
AFUA_6G13020AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (185 aa)
AFUA_6G12890Vacuole-associated enzyme activator complex component (Vac14), putative. (927 aa)
sec24Protein transport protein sec24; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity). (919 aa)
AFUA_6G12570EH domain binding protein epsin 2. (561 aa)
atg9Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Required for mitophagy. Cycles between the PAS and the cytoplasmic vesicle pool and may participate in supplying membrane for the growing autophagosome. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. Different machinerie [...] (951 aa)
fmqANonribosomal peptide synthetase fmqA; Nonribosomal peptide synthetase; part of the gene cluster that mediates the biosynthesis of the antitumor fumiquinazolines. The simplest member is fumiquinazoline F (FQF) with a 6-6-6 tricyclic core derived from anthranilic acid (Ant), tryptophan (Trp), and alanine (Ala). The trimodular NRPS fmqA is responsible for FQF formation. Modules 1, 2 and 3 of fmqA are predicted to activate and load Ant, Trp and Ala, respectively, providing for the assembly of an Ant-Trp-Ala-S-enzyme intermediate that would undergo double cyclization for chain release and g [...] (3955 aa)
fmqEMFS transporter fmqE; MFS transporter; part of the gene cluster that mediates the biosynthesis of the antitumor cytotoxic peptidyl alkaloids fumiquinazolines. Probably involved in fumiquinazolines metabolism and transport. Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (534 aa)
exo84Exocyst complex component exo84; Involved in the secretory pathway as part of the exocyst complex which tethers secretory vesicles to the sites of exocytosis. Plays a role in both the assembly of the exocyst and the polarization of this complex to specific sites of the plasma membrane for exocytosis. Also involved in assembly of the spliceosome (By similarity). (683 aa)
AFUA_6G10410E3 ubiquitin-protein ligase PEP5. (958 aa)
AFUA_6G08290ADP-ribosylation factor family protein. (175 aa)
AFUA_6G07930Uncharacterized protein. (406 aa)
AFUA_6G07560Transcription factor Rap1, putative. (315 aa)
AFUA_6G07490WD repeat protein. (1160 aa)
AFUA_6G074401-phosphatidylinositol-3-phosphate 5-kinase (Fab1), putative. (2475 aa)
AFUA_6G07290Endosomal cargo receptor (Erv14), putative. (138 aa)
AFUA_6G06910Uncharacterized protein. (786 aa)
AFUA_6G06390Uncharacterized protein. (62 aa)
sec13Protein transport protein sec13; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. It also functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport facto [...] (306 aa)
AFUA_4G06400pH signal transduction protein PalA, putative. (834 aa)
AFUA_4G06480DDENN domain protein. (1113 aa)
AFUA_4G07070Uncharacterized protein. (167 aa)
AFUA_4G07700Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1693 aa)
AFUA_4G08040RAB GTPase Ypt5, putative. (218 aa)
AFUA_4G08470Uncharacterized protein. (457 aa)
AFUA_4G10020Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (242 aa)
AFUA_4G10040SNARE complex subunit (Tlg2), putative; Belongs to the syntaxin family. (390 aa)
AFUA_4G10200Transcription factor RfeF, putative. (675 aa)
AFUA_4G10210Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1532 aa)
AFUA_4G10600GTPase activating protein (Gyp5), putative. (870 aa)
AFUA_4G10710Vesicle transport v-snare protein, putative. (224 aa)
AFUA_4G11000SNF7 family protein (Cta1), putative. (216 aa)
AFUA_4G11560Vacuolar protein sorting-associated protein; May be involved in recycling of membrane proteins between an endocytic compartment and the TGN; Belongs to the VPS13 family. (3187 aa)
AFUA_4G11590Uncharacterized protein. (488 aa)
AFUA_4G11810Uncharacterized protein. (203 aa)
AFUA_4G12060Vacuolar protein sorting-associated protein 26, putative. (349 aa)
AFUA_4G12070Endosomal peripheral membrane protein (Mon2), putative. (1688 aa)
AFUA_4G12290ESCRT-II complex component (Vps25), putative. (195 aa)
AFUA_4G12490Guanine nucleotide exchange factor Vps9, putative. (776 aa)
AFUA_4G12830Vacuolar protein sorting-associated protein Vps5, putative. (530 aa)
snx4Sorting nexin-4; Sorting nexin, involved in the separation or division of vacuoles throughout the entire life cycle of the cells. Involved in retrieval of late-Golgi SNAREs from post-Golgi endosomes to the trans- Golgi network, for cytoplasm to vacuole transport (Cvt), mitophagy, and pexophagy (By similarity). (497 aa)
erv25Endoplasmic reticulum vesicle protein 25; Constituent of COPII-coated endoplasmic reticulum-derived transport vesicles. Required for efficient transport of a subset of secretory proteins to the Golgi. Facilitates retrograde transport from the Golgi to the endoplasmic reticulum (By similarity); Belongs to the EMP24/GP25L family. (266 aa)
AFUA_4G13340DUF907 domain protein. (721 aa)
AFUA_4G13490AP-3 adaptor complex subunit mu, putative; Belongs to the adaptor complexes medium subunit family. (624 aa)
AFUA_4G14270Polyketide synthase, putative. (264 aa)
AFUA_1G16930Phosphatidylserine decarboxylase, putative. (346 aa)
AFUA_1G16320Vacuolar protein sorting-associated protein 28; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (244 aa)
AFUA_1G15890SacI domain protein. (937 aa)
AFUA_1G15860Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. (591 aa)
AFUA_1G15250Autophagy protein Atg27, putative. (333 aa)
ssh4Protein ssh4; Components of the endosome-vacuole trafficking pathway that regulates nutrient transport. May be involved in processes which determine whether plasma membrane proteins are degraded or routed to the plasma membrane (By similarity); Belongs to the SSH4 family. (507 aa)
mns1BProbable mannosyl-oligosaccharide alpha-1,2-mannosidase 1B; Involved in the maturation of Asn-linked oligosaccharides. Progressively trims alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2) (By similarity). (493 aa)
aps2AP-2 complex subunit sigma; Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration (By similarity). (145 aa)
AFUA_1G13960DUF292 domian protein. (332 aa)
AFUA_1G13590MHD domain-containing protein. (701 aa)
AFUA_1G13260Coatomer subunit epsilon; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Belongs to the COPE family. (269 aa)
end3Actin cytoskeleton-regulatory complex protein end3; Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity). (404 aa)
AFUA_1G12540TMEM1 family protein, putative. (1443 aa)
AFUA_1G11770COPII-coated vesicle protein SurF4/Erv29, putative. (303 aa)
AFUA_1G11470Endosomal cargo receptor (P24), putative. (218 aa)
AFUA_1G10970Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (955 aa)
AFUA_1G10950Vesicle-mediated transport protein Vid24, putative. (330 aa)
AFUA_1G10330Uncharacterized protein. (549 aa)
AFUA_1G09870VPS9 domain protein, putative. (1308 aa)
AFUA_1G09640Actin-interacting protein (Bud6/Aip3), putative. (1055 aa)
AFUA_1G09560Protein transport protein (LST8), putative. (415 aa)
AFUA_1G09480Vacuolar protein sorting-associated protein 29; Belongs to the VPS29 family. (195 aa)
AFUA_1G09220SNF7 family protein. (217 aa)
gmt1GDP-mannose transporter; Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen. (382 aa)
AFUA_5G05970Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family. (133 aa)
AFUA_5G06220Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (700 aa)
AFUA_5G06450Vacuolar protein sorting protein DigA. (961 aa)
AFUA_5G06520Low-temperature viability protein ltv1. (490 aa)
AFUA_5G07150Vacuolar protein sorting-associated protein 17; Plays a role in vesicular protein sorting. Belongs to the VPS17 family. (591 aa)
AFUA_5G07860Phosphatase family protein. (1061 aa)
AFUA_5G07930AP-2 adaptor complex subunit mu, putative; Belongs to the adaptor complexes medium subunit family. (445 aa)
AFUA_5G08230C3HC4 finger protein. (473 aa)
AFUA_5G08530Phosphatidylinositol 3,5-bisphosphate-binding protein, putative. (258 aa)
AFUA_5G08670Phosphatidylinositol 3-kinase VPS34. (898 aa)
AFUA_5G09660AP-1 adaptor complex subunit mu, putative; Belongs to the adaptor complexes medium subunit family. (446 aa)
AFUA_5G10630Chloride channel protein. (852 aa)
AFUA_5G10730Rad60-SLD_2 domain-containing protein. (267 aa)
atg18Autophagy-related protein 18; The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Necessary for proper vacuole morphology. Plays an important role in osmotically-induced vacuole fragmentation. Required for cytoplasm to vacuole transport (Cvt) vesicle formation, pexophagy and starvation- induced autophagy. Involved in correct atg9 trafficking to the pre- autophagosomal structure. Might also be involved in premeiotic DNA replication (By similarity). (436 aa)
AFUA_5G12130Rab small monomeric GTPase Rab7, putative. (171 aa)
AFUA_5G12880Trafficking protein particle complex subunit; Plays a key role in the late stages of endoplasmic reticulum to Golgi traffic. (258 aa)
AFUA_5G13320UV radiation resistance protein (UVRAG), putative. (619 aa)
AFUA_5G13410SNF7 family protein. (224 aa)
AFUA_5G13600Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology. (828 aa)
AFUA_5G13890SNF7 family protein. (229 aa)
AFUA_5G14060Rho GTPase Rho4, putative. (286 aa)
AFUA_5G14730Aldo-keto reductase (AKR13), putative. (341 aa)
fleAFucose-specific lectin; Multispecific lectin that is able to recognize L-fucose in all possible linkages. These could be found not only in decomposed plant matter in soil, which is the natural environment for A.fumigatus, but also in various epitopes on human tissues. Mediates binding of A.fumigatus conidia to airway mucinin a fucose dependent manner. Stimulates IL-8 production by human bronchial cells in a dose-dependent manner, contributing to the inflammatory response observed upon the exposure of a patient to A.fumigatus, and thus might be an important virulence factor involved in [...] (315 aa)
AFUA_3G05630Phospholipase. (1807 aa)
AFUA_3G06140Cytoskeleton assembly control protein Sla2, putative. (1043 aa)
AFUA_3G06430GDP/GTP exchange factor Sec2p, putative. (705 aa)
snx3Sorting nexin-3; Required for retention of late Golgi membrane proteins. Component of the retrieval machinery that functions by direct interaction with the cytosolic tails of certain TGN membrane proteins during the sorting/budding process at the prevacuolar compartment. Binds phosphatidylinositol 3-phosphate (PtdIns(P3)) (By similarity). (142 aa)
vma21Vacuolar ATPase assembly integral membrane protein vma21; Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum; Belongs to the VMA21 family. (127 aa)
AFUA_3G08730Endosome-associated ubiquitin isopeptidase (AmsH), putative. (532 aa)
AFUA_3G08790Uncharacterized protein. (294 aa)
AFUA_3G08840Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. (1212 aa)
AFUA_3G08970AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (746 aa)
AFUA_3G09360Vacuolar sorting ATPase Vps4, putative; Belongs to the AAA ATPase family. (435 aa)
AFUA_3G09700Sec23/Sec24 family protein. (1019 aa)
AFUA_3G10340Rho GTPase Rho 2, putative. (207 aa)
AFUA_3G10360Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (878 aa)
AFUA_3G10740RAB GTPase Vps21/Ypt51, putative. (262 aa)
AFUA_3G11200Vacuolar assembly protein, putative. (1298 aa)
AFUA_3G12520KxDL domain-containing protein. (153 aa)
AFUA_3G12800Clathrin-coated vesiclec protein (Bud7), putative. (712 aa)
AFUA_3G13340Rho-like small GTPase, putative. (192 aa)
AFUA_3G13770Vacuolar segregation protein (Pep7), putative. (672 aa)
PSD2Phosphatidylserine decarboxylase 2 alpha chain; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type II sub-subfamily. (1077 aa)
AFUA_3G14380Endosomal sorting complex protein TSG101, putative. (579 aa)
AFUA_2G17650DUF907 domain protein. (612 aa)
alb1Conidial pigment polyketide synthase alb1; Non-reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of dihydroxynaphthalene (DHN)-melanin, a bluish-green pigment and a structural component of the conidial wall. The first step of the pathway is the production of the heptaketide naphtopyrone YWA1 by the polyketide synthase alb1 though condensation of acetyl-CoA with malonyl-CoA. The naphtopyrone YWA1 is then converted to the pentaketide 1,3,6,8- tetrahydroxynaphthalene (1,3,6,8-THN) by the heptaketide hydrolyase ayg1 though chain-length shortening. 1,3,6, [...] (2146 aa)
ayg1Heptaketide hydrolyase ayg1; Heptaketide hydrolyase; part of the gene cluster that mediates the biosynthesis of dihydroxynaphthalene (DHN)-melanin, a bluish-green pigment and a structural component of the conidial wall. The first step of the pathway is the production of the heptaketide naphtopyrone YWA1 by the polyketide synthase alb1 though condensation of acetyl-CoA with malonyl-CoA. The naphtopyrone YWA1 is then converted to the pentaketide 1,3,6,8-tetrahydroxynaphthalene (1,3,6,8-THN) by the heptaketide hydrolyase ayp1 though chain-length shortening. 1,3,6,8-THN is substrate of the [...] (406 aa)
mvp1Sorting nexin mvp1; Required for vacuolar protein sorting. (729 aa)
AFUA_2G16800Lectin family integral membrane protein, putative. (328 aa)
AFUA_2G16670Uncharacterized protein. (742 aa)
AFUA_2G16520Phospholipase. (1101 aa)
AFUA_2G16390Sec2p domain-containing protein. (251 aa)
AFUA_2G15820SNARE complex subunit (Syn8), putative. (339 aa)
AFUA_2G15750Spindle pole body component. (826 aa)
AFUA_2G15080Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family. (175 aa)
AFUA_2G14900pH-signalling protein PalC. (509 aa)
AFUA_2G14270Coronin; Belongs to the WD repeat coronin family. (615 aa)
AFUA_2G14160Autophagy protein Atg20, putative. (636 aa)
AFUA_2G13750Vacuolar sorting protein, putative; Belongs to the STXBP/unc-18/SEC1 family. (666 aa)
AFUA_2G13440Chitin synthase ChsE; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1848 aa)
AFUA_2G13430Chitin synthase, putative. (1756 aa)
AFUA_2G13370Phosphatidylinositol 4-kinase type II subunit alpha, putative. (766 aa)
sec31Protein transport protein sec31; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity). (1263 aa)
AFUA_2G12180Lectin family integral membrane protein, putative. (327 aa)
AFUA_2G12140Chloride channel protein. (863 aa)
AFUA_2G12050ZIP metal ion transporter, putative. (389 aa)
bro1Vacuolar protein-sorting protein bro1; Involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles; Belongs to the BRO1 family. (976 aa)
AFUA_2G10930Protein RER1; Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment. (188 aa)
atg15Putative lipase atg15; Lipase which is essential for lysis of subvacuolar cytoplasm to vacuole targeted bodies and intravacuolar autophagic bodies. Involved in the lysis of intravacuolar multivesicular body (MVB) vesicles. The intravacuolar membrane disintegration by atg15 is critical to life span extension (By similarity); Belongs to the AB hydrolase superfamily. Lipase family. (650 aa)
AFUA_2G10610Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (855 aa)
AFUA_2G10340AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (718 aa)
AFUA_2G09830ARF GTPase activator (Glo3), putative. (386 aa)
AFUA_2G09180Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. (201 aa)
AFUA_2G08900Voltage-gated chloride channel (ClcA), putative. (911 aa)
AFUA_2G08720Trafficking protein particle complex subunit 2/Sedlin, putative. (187 aa)
AFUA_2G08180Flotillin domain protein; Belongs to the band 7/mec-2 family. Flotillin subfamily. (455 aa)
akr1Palmitoyltransferase akr1; Palmitoyltransferase specific for casein kinase 1. Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily. (738 aa)
Your Current Organism:
Aspergillus fumigatus
NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293
Server load: low (32%) [HD]