STRINGSTRING
AFUA_2G00090 AFUA_2G00090 AFUA_2G01090 AFUA_2G01090 ku80 ku80 AFUA_2G03910 AFUA_2G03910 AFUA_2G04960 AFUA_2G04960 AFUA_2G06320 AFUA_2G06320 AFUA_5G03320 AFUA_5G03320 AFUA_5G02520 AFUA_5G02520 AFUA_8G07400 AFUA_8G07400 AFUA_8G00430 AFUA_8G00430 AFUA_7G00090 AFUA_7G00090 AFUA_1G13060 AFUA_1G13060 AFUA_1G03035 AFUA_1G03035 swr1 swr1 AFUA_2G09060 AFUA_2G09060 MCM7 MCM7 AFUA_2G10820 AFUA_2G10820 dbp9 dbp9 AFUA_2G18100 AFUA_2G18100 AFUA_3G15395 AFUA_3G15395 AFUA_3G14010 AFUA_3G14010 chl1 chl1 AFUA_5G15150 AFUA_5G15150 PIF1 PIF1 AFUA_5G10890 AFUA_5G10890 AFUA_5G07740 AFUA_5G07740 AFUA_5G06600 AFUA_5G06600 ino80 ino80 AFUA_1G13910 AFUA_1G13910 AFUA_1G15120 AFUA_1G15120 AFUA_4G12680 AFUA_4G12680 AFUA_4G12430 AFUA_4G12430 AFUA_4G12210 AFUA_4G12210 psf3 psf3 AFUA_4G11180 AFUA_4G11180 rvb1 rvb1 AFUA_4G10650 AFUA_4G10650 AFUA_4G07230 AFUA_4G07230 AFUA_6G12910 AFUA_6G12910 AFUA_6G13080 AFUA_6G13080 ubc2 ubc2 AFUA_6G14670 AFUA_6G14670 AFUA_6G14690 AFUA_6G14690 AFUA_6G14720 AFUA_6G14720 rvb2 rvb2 mph1 mph1 AFUA_1G03920 AFUA_1G03920
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AFUA_2G00090Telomere-associated RecQ helicase, putative. (460 aa)
AFUA_2G01090DNA helicase, putative. (730 aa)
ku80ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase. Involved in non-homologous end joining (NHEJ) DNA double strand break repair. DNA-binding is sequence-independent but has a high affinity to nicks in double-stranded DNA and to the ends of duplex DNA. Binds to naturally occurring chromosomal ends, and therefore provides chromosomal end protection. Required also for telomere recombination to repair telomeric ends in the absence of telomerase. ku70, of the ku70/ku80 heterodimer, binds to the stem loop of tlc1, the RNA component of telomerase. I [...] (725 aa)
AFUA_2G03910ATP-depentend DNA helicase, putative. (1001 aa)
AFUA_2G04960RecQ family helicase MusN. (1563 aa)
AFUA_2G06320Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (529 aa)
AFUA_5G03320TFIIH complex helicase Ssl2, putative. (830 aa)
AFUA_5G02520DNA helicase; Belongs to the MCM family. (718 aa)
AFUA_8G07400Telomere-associated RecQ helicase, putative. (360 aa)
AFUA_8G00430EthD domain-containing protein. (157 aa)
AFUA_7G00090Telomere-associated RecQ helicase, putative. (396 aa)
AFUA_1G13060Regulator of nonsense transcripts, putative. (1079 aa)
AFUA_1G03035HD superfamily hydrolase, putative. (243 aa)
swr1Helicase swr1; Catalytic component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling; Belongs to the SNF2/RAD54 helicase family. SWR1 subfamily. (1695 aa)
AFUA_2G09060DNA helicase; Belongs to the MCM family. (1023 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (854 aa)
AFUA_2G10820DEAD/DEAH box helicase, putative. (1206 aa)
dbp9ATP-dependent RNA helicase dbp9; ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs; Belongs to the DEAD box helicase family. DDX56/DBP9 subfamily. (649 aa)
AFUA_2G18100Telomere-associated RecQ helicase, putative. (850 aa)
AFUA_3G15395Telomere-associated RecQ helicase, putative. (714 aa)
AFUA_3G14010DNA helicase; Belongs to the MCM family. (896 aa)
chl1ATP-dependent DNA helicase chl1; ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (By similarity). May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (By similarity). Has a specific role in chromosome segregation during meiosis II (By similarity). (782 aa)
AFUA_5G15150Telomere-associated RecQ helicase, putative. (395 aa)
PIF1ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (788 aa)
AFUA_5G10890DNA helicase; Belongs to the MCM family. (956 aa)
AFUA_5G07740DSB repair complex subunit Ku70, putative. (691 aa)
AFUA_5G06600SNF2 family helicase/ATPase, putative. (1827 aa)
ino80Chromatin-remodeling ATPase INO80; ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair. (1708 aa)
AFUA_1G13910TFIIH complex helicase Rad3, putative. (770 aa)
AFUA_1G15120DsDNA-dependent ATPase (Rad54b), putative. (969 aa)
AFUA_4G12680DNA repair protein Rad50. (1312 aa)
AFUA_4G12430PSF1 domain protein. (253 aa)
AFUA_4G12210DNA replication helicase Dna2, putative. (1657 aa)
psf3DNA replication complex GINS protein psf3; The GINS complex plays an essential role in the initiation of DNA replication. (178 aa)
AFUA_4G11180AAA family ATPase, putative. (539 aa)
rvb1RuvB-like helicase 1; DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity); Belongs to the RuvB family. (458 aa)
AFUA_4G10650Uncharacterized protein. (198 aa)
AFUA_4G07230ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (538 aa)
AFUA_6G12910DsDNA-dependent ATPase Rad54, putative. (807 aa)
AFUA_6G13080DEAD/DEAH box DNA helicase (Mer3), putative. (1439 aa)
ubc2Ubiquitin-conjugating enzyme E2 2; Catalyzes the covalent attachment of ubiquitin to other proteins. Plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation. Also involved in postreplication repair of UV-damaged DNA, in N-end rule-dependent protein degradation and in sporulation; Belongs to the ubiquitin-conjugating enzyme family. (151 aa)
AFUA_6G14670C2H2-type domain-containing protein. (146 aa)
AFUA_6G14690Telomere-associated RecQ helicase, putative. (352 aa)
AFUA_6G14720Telomere-associated RecQ helicase, putative. (1445 aa)
rvb2RuvB-like helicase 2; DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity); Belongs to the RuvB family. (469 aa)
mph1ATP-dependent DNA helicase mph1; ATP-dependent DNA helicase involved in DNA damage repair by homologous recombination and in genome maintenance. Capable of unwinding D-loops. Plays a role in limiting crossover recombinants during mitotic DNA double-strand break (DSB) repair. Component of a FANCM-MHF complex which promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork. Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily. (1101 aa)
AFUA_1G03920DNA helicase; Belongs to the MCM family. (892 aa)
Your Current Organism:
Aspergillus fumigatus
NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293
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