STRINGSTRING
AFUA_4G07835 AFUA_4G07835 AFUA_6G05174 AFUA_6G05174 AFUA_8G01830 AFUA_8G01830 AFUA_1G11870 AFUA_1G11870 AFUA_1G13330 AFUA_1G13330 AFUA_6G11190 AFUA_6G11190 AFUA_4G01260 AFUA_4G01260 AFUA_4G04620 AFUA_4G04620 AFUA_4G04560 AFUA_4G04560 AFUA_4G04100 AFUA_4G04100 AFUA_4G03990 AFUA_4G03990 AFUA_4G03870 AFUA_4G03870 AFUA_7G01230 AFUA_7G01230 AFUA_7G01860 AFUA_7G01860 AFUA_8G02170 AFUA_8G02170 vps10 vps10 AFUA_8G05350 AFUA_8G05350 AFUA_8G05240 AFUA_8G05240 AFUA_8G05160 AFUA_8G05160 AFUA_8G04260 AFUA_8G04260 AFUA_8G04140 AFUA_8G04140 AFUA_8G04030 AFUA_8G04030 AFUA_6G02420 AFUA_6G02420 AFUA_6G03850 AFUA_6G03850 sec16 sec16 AFUA_6G03990 AFUA_6G03990 AFUA_6G04010 AFUA_6G04010 mmm1 mmm1 AFUA_6G05050 AFUA_6G05050 AFUA_6G05110 AFUA_6G05110 AFUA_5G01180 AFUA_5G01180 AFUA_5G01460 AFUA_5G01460 AFUA_5G01960 AFUA_5G01960 AFUA_5G02200 AFUA_5G02200 AFUA_5G02360 AFUA_5G02360 AFUA_5G03220 AFUA_5G03220 AFUA_5G03630 AFUA_5G03630 AFUA_5G03640 AFUA_5G03640 AFUA_5G03880 AFUA_5G03880 AFUA_5G04280 AFUA_5G04280 AFUA_3G04060 AFUA_3G04060 AFUA_3G03520 AFUA_3G03520 AFUA_3G02213 AFUA_3G02213 AFUA_3G02210 AFUA_3G02210 AFUA_7G03640 AFUA_7G03640 AFUA_7G04150 AFUA_7G04150 AFUA_7G04250 AFUA_7G04250 AFUA_7G04260 AFUA_7G04260 mia40 mia40 AFUA_7G05970 AFUA_7G05970 AFUA_7G06040 AFUA_7G06040 AFUA_7G08630 AFUA_7G08630 AFUA_2G05470 AFUA_2G05470 AFUA_2G05440 AFUA_2G05440 mon1 mon1 vps27 vps27 hse1 hse1 AFUA_2G04620 AFUA_2G04620 AFUA_2G04610 AFUA_2G04610 AFUA_2G04390 AFUA_2G04390 AFUA_2G04270 AFUA_2G04270 AFUA_2G04140 AFUA_2G04140 tim50 tim50 AFUA_2G02980 AFUA_2G02980 pam18 pam18 AFUA_2G02500 AFUA_2G02500 AFUA_2G02430 AFUA_2G02430 AFUA_2G01990 AFUA_2G01990 AFUA_2G01660 AFUA_2G01660 AFUA_2G01130 AFUA_2G01130 tim9 tim9 AFUA_1G06880 AFUA_1G06880 AFUA_1G06790 AFUA_1G06790 AFUA_1G06680 AFUA_1G06680 AFUA_1G06630 AFUA_1G06630 AFUA_1G06510 AFUA_1G06510 AFUA_1G06420 AFUA_1G06420 AFUA_1G04950 AFUA_1G04950 AFUA_1G04890 AFUA_1G04890 AFUA_1G04800 AFUA_1G04800 tim10 tim10 AFUA_1G03940 AFUA_1G03940 AFUA_1G03590 AFUA_1G03590 AFUA_1G03560 AFUA_1G03560 npl4 npl4 AFUA_1G02430 AFUA_1G02430 AFUA_1G02170 AFUA_1G02170 pam17 pam17 AFUA_1G01720 AFUA_1G01720 AFUA_1G00230 AFUA_1G00230 AFUA_6G13300 AFUA_6G13300 AFUA_6G13120 AFUA_6G13120 AFUA_6G13080 AFUA_6G13080 AFUA_6G12430 AFUA_6G12430 AFUA_6G11380 AFUA_6G11380 AFUA_6G11030 AFUA_6G11030 AFUA_6G10700 AFUA_6G10700 AFUA_6G10630 AFUA_6G10630 AFUA_6G10360 AFUA_6G10360 AFUA_6G09990 AFUA_6G09990 AFUA_6G09390 AFUA_6G09390 oct1 oct1 AFUA_6G08230 AFUA_6G08230 creD creD AFUA_6G06390 AFUA_6G06390 sec13 sec13 AFUA_4G06300 AFUA_4G06300 get1 get1 AFUA_4G10180 AFUA_4G10180 AFUA_4G11560 AFUA_4G11560 tim54 tim54 AFUA_4G11940 AFUA_4G11940 AFUA_4G12070 AFUA_4G12070 AFUA_4G12080 AFUA_4G12080 AFUA_4G12270 AFUA_4G12270 AFUA_4G12290 AFUA_4G12290 AFUA_4G12400 AFUA_4G12400 AFUA_4G12830 AFUA_4G12830 AFUA_1G17490 AFUA_1G17490 AFUA_1G16970 AFUA_1G16970 AFUA_1G16820 AFUA_1G16820 AFUA_1G16540 AFUA_1G16540 AFUA_1G16320 AFUA_1G16320 AFUA_1G15900 AFUA_1G15900 AFUA_1G15720 AFUA_1G15720 AFUA_1G15400 AFUA_1G15400 AFUA_1G14940 AFUA_1G14940 ssh4 ssh4 mdm12 mdm12 AFUA_1G14780 AFUA_1G14780 AFUA_1G14200 AFUA_1G14200 AFUA_1G13180 AFUA_1G13180 AFUA_1G12020 AFUA_1G12020 AFUA_1G11860 AFUA_1G11860 AFUA_1G11470 AFUA_1G11470 AFUA_1G10950 AFUA_1G10950 AFUA_1G10640 AFUA_1G10640 AFUA_1G09840 AFUA_1G09840 AFUA_1G09830 AFUA_1G09830 hulA hulA AFUA_1G08970 AFUA_1G08970 AFUA_5G05800 AFUA_5G05800 AFUA_5G06300 AFUA_5G06300 AFUA_5G06960 AFUA_5G06960 AFUA_5G08060 AFUA_5G08060 AFUA_5G08130 AFUA_5G08130 AFUA_5G08440 AFUA_5G08440 AFUA_5G09000 AFUA_5G09000 AFUA_5G09020 AFUA_5G09020 AFUA_5G10710 AFUA_5G10710 AFUA_5G11100 AFUA_5G11100 AFUA_5G11360 AFUA_5G11360 AFUA_5G11370 AFUA_5G11370 AFUA_5G11750 AFUA_5G11750 AFUA_5G12170 AFUA_5G12170 AFUA_5G12180 AFUA_5G12180 AFUA_5G12530 AFUA_5G12530 AFUA_5G12760 AFUA_5G12760 AFUA_5G12820 AFUA_5G12820 AFUA_5G13410 AFUA_5G13410 mdmB mdmB AFUA_5G13600 AFUA_5G13600 AFUA_5G13890 AFUA_5G13890 AFUA_3G05820 AFUA_3G05820 AFUA_3G06850 AFUA_3G06850 AFUA_3G06901 AFUA_3G06901 AFUA_3G06980 AFUA_3G06980 AFUA_3G07280 AFUA_3G07280 AFUA_3G07630 AFUA_3G07630 AFUA_3G08100 AFUA_3G08100 AFUA_3G08230 AFUA_3G08230 AFUA_3G08590 AFUA_3G08590 AFUA_3G08730 AFUA_3G08730 AFUA_3G08850 AFUA_3G08850 AFUA_3G09360 AFUA_3G09360 AFUA_3G09790 AFUA_3G09790 AFUA_3G10060 AFUA_3G10060 AFUA_3G10190 AFUA_3G10190 AFUA_3G10360 AFUA_3G10360 AFUA_3G10460 AFUA_3G10460 AFUA_3G10650 AFUA_3G10650 AFUA_3G10740 AFUA_3G10740 AFUA_3G10940 AFUA_3G10940 AFUA_3G11200 AFUA_3G11200 get3 get3 AFUA_3G11860 AFUA_3G11860 AFUA_3G12250 AFUA_3G12250 AFUA_3G12360 AFUA_3G12360 AFUA_3G12370 AFUA_3G12370 sec11 sec11 AFUA_3G13000 AFUA_3G13000 nop58 nop58 AFUA_3G13840 AFUA_3G13840 AFUA_3G14380 AFUA_3G14380 mvp1 mvp1 AFUA_2G16730 AFUA_2G16730 AFUA_2G16430 AFUA_2G16430 AFUA_2G16090 AFUA_2G16090 AFUA_2G15870 AFUA_2G15870 AFUA_2G14760 AFUA_2G14760 AFUA_2G14190 AFUA_2G14190 AFUA_2G13040 AFUA_2G13040 AFUA_2G12580 AFUA_2G12580 tim13 tim13 bro1 bro1 AFUA_2G10980 AFUA_2G10980 AFUA_2G10930 AFUA_2G10930 AFUA_2G10150 AFUA_2G10150 AFUA_2G10010 AFUA_2G10010 tim21 tim21 AFUA_2G09290 AFUA_2G09290 AFUA_2G08080 AFUA_2G08080 AFUA_2G07600 AFUA_2G07600
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AFUA_4G07835Nuclear transport factor 2 domain protein, putative. (162 aa)
AFUA_6G05174TOM complex component Tom7, putative. (53 aa)
AFUA_8G01830Zn(2)-C6 fungal-type domain-containing protein. (497 aa)
AFUA_1G11870Mitochondrial processing peptidase alpha subunit, putative; Belongs to the peptidase M16 family. (581 aa)
AFUA_1G13330Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (388 aa)
AFUA_6G11190Protein kinase (VPS15), putative. (1637 aa)
AFUA_4G01260Mitochondrial chaperone ATPase (Bcs1), putative; Belongs to the AAA ATPase family. (520 aa)
AFUA_4G04620Mitochondrial outer membrane protein (Sam50), putative. (544 aa)
AFUA_4G04560GTP binding protein, putative. (565 aa)
AFUA_4G04100Vacuolar protein sorting protein (Vps36), putative. (537 aa)
AFUA_4G03990Membrane-spanning ATPase, putative; Belongs to the AAA ATPase family. (419 aa)
AFUA_4G03870Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (260 aa)
AFUA_7G01230DnaJ domain protein. (480 aa)
AFUA_7G01860Heat shock protein (Sti1), putative. (585 aa)
AFUA_8G02170C6 finger domain protein, putative. (462 aa)
vps10Vacuolar protein sorting/targeting protein 10; Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A. Executes multiple rounds of sorting by cycling between the late Golgi and a prevacuolar endosome-like compartment (By similarity); Belongs to the VPS10-related sortilin family. (1487 aa)
AFUA_8G05350ER membrane protein complex subunit 3; The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER). Belongs to the EMC3 family. (268 aa)
AFUA_8G05240Peroxisomal targeting signal-1 receptor (PEX5), putaitve. (569 aa)
AFUA_8G05160Peroxisomal membrane protein (Pex13), putative. (444 aa)
AFUA_8G04260Translocation protein (Sec66), putative. (266 aa)
AFUA_8G04140Uncharacterized protein. (772 aa)
AFUA_8G04030Probable lysosomal cobalamin transporter; Probable lysosomal cobalamin transporter. Required to export cobalamin from lysosomes allowing its conversion to cofactors (By similarity); Belongs to the LIMR family. LMBRD1 subfamily. (572 aa)
AFUA_6G02420Ubiquitin conjugating enzyme (UbcM), putative; Belongs to the ubiquitin-conjugating enzyme family. (149 aa)
AFUA_6G03850Signal sequence receptor alpha subunit, putative. (649 aa)
sec16COPII coat assembly protein sec16; Involved in the initiation of assembly of the COPII coat required for the formation of transport vesicles from the endoplasmic reticulum (ER) and the selection of cargo molecules. Also involved in autophagy (By similarity); Belongs to the SEC16 family. (1832 aa)
AFUA_6G03990GAS2 domain protein. (1494 aa)
AFUA_6G04010Chromosome segregation protein Cse1, putative. (983 aa)
mmm1Maintenance of mitochondrial morphology protein 1; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The mdm12-mmm1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta- barrel proteins, and acts in a late step after the SAM complex. The mdm10-mdm12-mmm1 su [...] (496 aa)
AFUA_6G05050DUF410 domain protein. (346 aa)
AFUA_6G05110Mitochondrial import receptor subunit (Tom40), putative. (355 aa)
AFUA_5G01180RAN small monomeric GTPase (Ran), putative. (480 aa)
AFUA_5G01460C6 finger domain protein, putative. (480 aa)
AFUA_5G01960Phosphate transporter (Pho88), putative. (186 aa)
AFUA_5G02200Mitochondrial import inner membrane translocase subunit (TIM22), putative. (175 aa)
AFUA_5G02360Vacuolar dynamin-like GTPase VpsA, putative; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (698 aa)
AFUA_5G03220Signal peptidase subunit 3. (252 aa)
AFUA_5G03630Uncharacterized protein. (130 aa)
AFUA_5G03640Mitochondrial export translocase Oxa1, putative. (436 aa)
AFUA_5G03880Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (522 aa)
AFUA_5G04280DUF2012 domain-containing protein. (245 aa)
AFUA_3G04060SNF7 family protein Fti1/Did2, putative. (209 aa)
AFUA_3G03520Integral membrane protein. (446 aa)
AFUA_3G02213Uncharacterized protein. (339 aa)
AFUA_3G02210C6 transcription factor, putative. (365 aa)
AFUA_7G03640AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane. (953 aa)
AFUA_7G04150Cochaperone Pam16. (173 aa)
AFUA_7G04250Protein-ER retention protein (Erd1), putative. (401 aa)
AFUA_7G04260Peroxisome biosynthesis protein (Peroxin-10), putative. (377 aa)
mia40Mitochondrial intermembrane space import and assembly protein 40; Required for the import and folding of small cysteine- containing proteins (small Tim) in the mitochondrial intermembrane space (IMS). Forms a redox cycle with ERV1 that involves a disulfide relay system. Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitochondria. The oxidized form of MIA40 forms a transient intermolecular disulfide bridge with the reduced precursor protein, resulting in oxidation of the precursor protein that now contains an intramolecular disulfide bond [...] (297 aa)
AFUA_7G05970mRNA transport regulator (Mtr10), putative. (977 aa)
AFUA_7G06040Uncharacterized membrane protein. (184 aa)
AFUA_7G08630Uncharacterized protein. (459 aa)
AFUA_2G05470Sister chromatid cohesion protein. (1772 aa)
AFUA_2G05440CTLH domain-containing protein. (229 aa)
mon1Vacuolar fusion protein mon1; Required for multiple vacuole delivery pathways including the cytoplasm to vacuole transport (Cvt), autophagy, pexophagy and endocytosis; Belongs to the MON1/SAND family. (621 aa)
vps27Vacuolar protein sorting-associated protein 27; Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane. (729 aa)
hse1Class E vacuolar protein-sorting machinery protein hse1; Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB). (584 aa)
AFUA_2G04620Hsp70 chaperone BiP/Kar2, putative; Belongs to the heat shock protein 70 family. (672 aa)
AFUA_2G04610DUF967 domain protein. (188 aa)
AFUA_2G04390Cytomegalovirus gH-receptor family protein, putative. (1034 aa)
AFUA_2G04270Mitochondrial inner membrane translocase subunit (TIM17), putative. (154 aa)
AFUA_2G04140Chromosome segregation protein Spc105, putative. (1559 aa)
tim50Mitochondrial import inner membrane translocase subunit tim50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Required to direct preproteins in transit and direct them to the channel protein TIM23, and possibly facilitates transfer of the translocating proteins from the TOM complex to the TIM23 complex (By similarity). (501 aa)
AFUA_2G02980Protein-ER retention receptor, putative. (337 aa)
pam18Mitochondrial import inner membrane translocase subunit tim14; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to stimulate activity of mtHSP70 (SSC1/sscA) (By similarity); Belongs to the TIM14 family. (105 aa)
AFUA_2G02500DUF2263 domain-containing protein. (271 aa)
AFUA_2G02430Mitochondrial genome maintenance protein Mgr2, putative. (108 aa)
AFUA_2G01990Signal recognition particle 14kD protein, putative. (139 aa)
AFUA_2G01660Mitochondrial outer membrane translocase receptor (TOM70), putative. (630 aa)
AFUA_2G01130Ubiquitin conjugating enzyme (UbcJ), putative; Belongs to the ubiquitin-conjugating enzyme family. (164 aa)
tim9Mitochondrial import inner membrane translocase subunit tim9; Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta- barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity); Belongs to the small Tim family. (90 aa)
AFUA_1G06880Mitochondrial export translocase Oxa2, putative. (342 aa)
AFUA_1G06790Importin beta-3 subunit, putative. (1095 aa)
AFUA_1G06680VHS domain protein. (642 aa)
AFUA_1G06630Golgi phosphoprotein 3 (GPP34) domain containing protein. (353 aa)
AFUA_1G06510Uncharacterized protein. (280 aa)
AFUA_1G06420SNF7 family protein. (241 aa)
AFUA_1G04950Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (323 aa)
AFUA_1G04890Translocon protein Sec61beta, putative. (131 aa)
AFUA_1G04800Protein phosphatase PP1 regulatory subunit Sds22, putative. (356 aa)
tim10Mitochondrial import inner membrane translocase subunit tim10; Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta- barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity); Belongs to the small Tim family. (93 aa)
AFUA_1G03940Signal recognition particle subunit SRP68; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP68 family. (646 aa)
AFUA_1G03590Importin 11, putative. (1045 aa)
AFUA_1G03560Peroxisome biosynthesis protein (Peroxin-2), putative. (479 aa)
npl4Nuclear protein localization protein 4; Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity); Belongs to the NPL4 family. (652 aa)
AFUA_1G02430Ubiquitin fusion degradation protein Ufd1, putative. (384 aa)
AFUA_1G02170ATP-dependent Clp protease, putative. (638 aa)
pam17Presequence translocated-associated motor subunit pam17, mitochondrial; Component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. (247 aa)
AFUA_1G01720Protein kinase and ribonuclease Ire1, putative. (1165 aa)
AFUA_1G00230Uncharacterized protein. (759 aa)
AFUA_6G13300GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (215 aa)
AFUA_6G13120Filament-forming protein (Tpr/p270), putative. (2009 aa)
AFUA_6G13080DEAD/DEAH box DNA helicase (Mer3), putative. (1439 aa)
AFUA_6G12430Ran-interacting protein Mog1, putative. (228 aa)
AFUA_6G11380Mitochondrial import receptor subunit (Tom20), putative. (169 aa)
AFUA_6G11030RNA binding protein MSSP-2, putative. (624 aa)
AFUA_6G10700Chaperonin, putative; Belongs to the GroES chaperonin family. (122 aa)
AFUA_6G10630GPN-loop GTPase 2; Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family. (381 aa)
AFUA_6G10360Protein required for cell viability, putative. (994 aa)
AFUA_6G09990Importin beta-4 subunit, putative. (1095 aa)
AFUA_6G09390Uncharacterized protein. (719 aa)
oct1Mitochondrial intermediate peptidase; Cleaves proteins, imported into the mitochondrion, to their mature size. While most mitochondrial precursor proteins are processed to the mature form in one step by mitochondrial processing peptidase (MPP), the sequential cleavage by MIP of an octapeptide after initial processing by MPP is a required step for a subgroup of nuclear-encoded precursor proteins destined for the matrix or the inner membrane (By similarity). (801 aa)
AFUA_6G08230Mitochondrial import protein Zim17, putative. (195 aa)
creDProbable HECT-type ubiquitin ligase-interacting protein creD; Component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB. May be involved in signaling by recognizing appropriately phosphorylated substrates via its arrestin domains and then recruit a HECT-type ubiquitin ligase such as hulA, leading to ubiquitination of the substrate, providing a link between ubiquitination and phosphorylation in protein regulation and stability (By similarity). (601 aa)
AFUA_6G06390Uncharacterized protein. (62 aa)
sec13Protein transport protein sec13; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. It also functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport facto [...] (306 aa)
AFUA_4G06300Uncharacterized protein. (382 aa)
get1Protein get1; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble get3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. (200 aa)
AFUA_4G10180Signal recognition particle subunit SRP72; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP72 family. (647 aa)
AFUA_4G11560Vacuolar protein sorting-associated protein; May be involved in recycling of membrane proteins between an endocytic compartment and the TGN; Belongs to the VPS13 family. (3187 aa)
tim54Mitochondrial import inner membrane translocase subunit tim54; Essential component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin- pore translocase that uses the membrane potential as external driving force (By similarity). (439 aa)
AFUA_4G11940DUF2263 domain-containing protein. (335 aa)
AFUA_4G12070Endosomal peripheral membrane protein (Mon2), putative. (1688 aa)
AFUA_4G12080Ubiquitin conjugating enzyme (MmsB), putative. (139 aa)
AFUA_4G12270LIM domain protein. (806 aa)
AFUA_4G12290ESCRT-II complex component (Vps25), putative. (195 aa)
AFUA_4G12400PHD finger domain protein, putative. (836 aa)
AFUA_4G12830Vacuolar protein sorting-associated protein Vps5, putative. (530 aa)
AFUA_1G17490Glucokinase regulator family protein, putative. (657 aa)
AFUA_1G16970ADP-ribosylation factor family protein. (249 aa)
AFUA_1G16820Signal recognition particle 19 kDa protein, putative. (257 aa)
AFUA_1G16540WD40 domain protein. (479 aa)
AFUA_1G16320Vacuolar protein sorting-associated protein 28; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (244 aa)
AFUA_1G15900Importin beta-2 subunit, putative. (937 aa)
AFUA_1G15720Importin beta-1 subunit. (872 aa)
AFUA_1G15400Peroxisome biosynthesis protein (Peroxine-7), putative. (356 aa)
AFUA_1G14940Protein translocation complex componenet (Npl1), putative. (697 aa)
ssh4Protein ssh4; Components of the endosome-vacuole trafficking pathway that regulates nutrient transport. May be involved in processes which determine whether plasma membrane proteins are degraded or routed to the plasma membrane (By similarity); Belongs to the SSH4 family. (507 aa)
mdm12Mitochondrial distribution and morphology protein 12; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. Mdm12 is required for the interaction of the ER-resident membrane protein mmm1 and the outer mitochondrial membrane-resident beta-barrel protein mdm10. The mdm12-mmm1 subcomplex functions in the major beta-barrel assembly pat [...] (439 aa)
AFUA_1G14780BAP31 domain protein, putative. (212 aa)
AFUA_1G14200Mitochondrial processing peptidase beta subunit, putative; Belongs to the peptidase M16 family. (479 aa)
AFUA_1G13180Mitochondrial outer membrane protein (Sam35), putative. (296 aa)
AFUA_1G12020Arrestin domain protein. (814 aa)
AFUA_1G11860Mitochondrial import receptor subunit tom22. (143 aa)
AFUA_1G11470Endosomal cargo receptor (P24), putative. (218 aa)
AFUA_1G10950Vesicle-mediated transport protein Vid24, putative. (330 aa)
AFUA_1G10640GPN-loop GTPase 3; Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family. (293 aa)
AFUA_1G09840Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family. (523 aa)
AFUA_1G09830Hsc70 cochaperone (SGT), putative. (341 aa)
hulAProbable E3 ubiquitin-protein ligase hulA; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Probably involved in the regulatory network controlling carbon source utilization. (813 aa)
AFUA_1G08970Uncharacterized protein. (441 aa)
AFUA_5G05800Microsomal signal peptidase Spc12, putative. (102 aa)
AFUA_5G06300Peroxisomal membrane protein (Pex3), putative. (528 aa)
AFUA_5G06960Uncharacterized protein. (212 aa)
AFUA_5G08060Importin 13, putative. (1025 aa)
AFUA_5G08130Protein transport protein Sec61 alpha subunit, putative. (478 aa)
AFUA_5G08440Uncharacterized protein. (286 aa)
AFUA_5G09000Sister chromatid cohesion protein (Eso1), putative. (672 aa)
AFUA_5G09020ER membrane protein Wsc4, putative. (330 aa)
AFUA_5G10710Uncharacterized protein. (442 aa)
AFUA_5G11100DUF775 domain protein. (241 aa)
AFUA_5G11360AP-3 adaptor complex subunit beta, putative. (843 aa)
AFUA_5G11370Serine/threonine-protein phosphatase. (340 aa)
AFUA_5G11750Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. (932 aa)
AFUA_5G12170Uncharacterized protein. (808 aa)
AFUA_5G12180Ran-specific GTPase-activating protein 1, putative. (247 aa)
AFUA_5G12530Arrestin (Or S-antigen), N-terminal domain protein. (525 aa)
AFUA_5G12760CCCH zinc finger DNA binding protein. (429 aa)
AFUA_5G12820Mitochondrial inner membrane protease subunit 1, putative. (179 aa)
AFUA_5G13410SNF7 family protein. (224 aa)
mdmBMitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. mdm10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the tom40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of tom40 with the recepto [...] (471 aa)
AFUA_5G13600Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology. (828 aa)
AFUA_5G13890SNF7 family protein. (229 aa)
AFUA_3G05820ZZ type zinc finger domain protein. (838 aa)
AFUA_3G06850Uncharacterized protein. (296 aa)
AFUA_3G06901Protein translocation complex subunit Sss1, putative. (88 aa)
AFUA_3G06980Uncharacterized protein. (304 aa)
AFUA_3G07280Uncharacterized protein. (335 aa)
AFUA_3G07630Metallo-beta-lactamase superfamily protein. (179 aa)
AFUA_3G08100Checkpoint protein kinase, putative. (841 aa)
AFUA_3G08230MRS7 family protein. (614 aa)
AFUA_3G08590Uncharacterized protein. (125 aa)
AFUA_3G08730Endosome-associated ubiquitin isopeptidase (AmsH), putative. (532 aa)
AFUA_3G08850Sulfhydryl oxidase. (220 aa)
AFUA_3G09360Vacuolar sorting ATPase Vps4, putative; Belongs to the AAA ATPase family. (435 aa)
AFUA_3G09790Uncharacterized protein. (211 aa)
AFUA_3G10060Dor1-like family protein. (478 aa)
AFUA_3G10190Peroxisomal membrane anchor protein (Pex14), putative. (416 aa)
AFUA_3G10360Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (878 aa)
AFUA_3G10460Nuclear transport factor NTF-2, putative. (124 aa)
AFUA_3G10650Glutamate carboxypeptidase Tre2, putative. (907 aa)
AFUA_3G10740RAB GTPase Vps21/Ypt51, putative. (262 aa)
AFUA_3G10940Peroxisomal membrane protein receptor Pex19, putative. (389 aa)
AFUA_3G11200Vacuolar assembly protein, putative. (1298 aa)
get3ATPase get3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...] (340 aa)
AFUA_3G11860Microtubule associated protein EB1, putative. (278 aa)
AFUA_3G12250Protein-tyrosine phosphatase, putative. (613 aa)
AFUA_3G12360Uncharacterized protein. (514 aa)
AFUA_3G12370V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (161 aa)
sec11Signal peptidase complex catalytic subunit sec11; Catalytic component of the signal peptidase complex (SPC), which catalyzes the cleavage of N-terminal signal sequences of proteins targeted to the endoplasmic reticulum. Signal peptide cleavage occurs during the translocation (cotranslationally or post-translationally) through the translocon pore into the endoplasmic reticulum (By similarity). (192 aa)
AFUA_3G13000Mitochondrial chaperone BCS1, putative; Belongs to the AAA ATPase family. (499 aa)
nop58Nucleolar protein 58; Required for pre-18S rRNA processing. May bind microtubules (By similarity); Belongs to the NOP5/NOP56 family. (591 aa)
AFUA_3G13840Mitochondrial inner membrane protease subunit Imp2, putative. (297 aa)
AFUA_3G14380Endosomal sorting complex protein TSG101, putative. (579 aa)
mvp1Sorting nexin mvp1; Required for vacuolar protein sorting. (729 aa)
AFUA_2G16730Peroxisome biosynthesis protein (PAS10/Peroxin-12), putative. (486 aa)
AFUA_2G16430Uncharacterized protein. (200 aa)
AFUA_2G16090Importin subunit alpha; Belongs to the importin alpha family. (552 aa)
AFUA_2G15870Importin beta-5 subunit, putative. (1042 aa)
AFUA_2G14760BCS1-like ATPase, putative; Belongs to the AAA ATPase family. (574 aa)
AFUA_2G14190Mitochondrial import inner membrane translocase subunit TIM23, putative. (212 aa)
AFUA_2G13040GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. (250 aa)
AFUA_2G12580Translocation protein Sec62, putative. (401 aa)
tim13Mitochondrial import inner membrane translocase subunit tim13; Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIM8- TIM13 complex is non essential and only mediates [...] (113 aa)
bro1Vacuolar protein-sorting protein bro1; Involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles; Belongs to the BRO1 family. (976 aa)
AFUA_2G10980ADP-ribosylation factor, putative; Belongs to the small GTPase superfamily. Arf family. (182 aa)
AFUA_2G10930Protein RER1; Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment. (188 aa)
AFUA_2G10150Peroxisome biosynthesis protein (PAS1/Peroxin-1), putative. (1211 aa)
AFUA_2G10010Nonsense-mediated mRNA decay protein (Nmd5), putative. (1048 aa)
tim21Mitochondrial import inner membrane translocase subunit tim21; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Required to keep the TOM and the TIM23 complexes in close contact. At some point, it is released from the TOM23 complex to allow protein translocation into the mitochondrial matrix (By similarity). (237 aa)
AFUA_2G09290Antigenic mitochondrial protein HSP60, putative; Belongs to the chaperonin (HSP60) family. (587 aa)
AFUA_2G08080Phospholipid metabolism enzyme regulator, putative. (906 aa)
AFUA_2G07600SRP receptor beta subunit (Srp102), putative. (352 aa)
Your Current Organism:
Aspergillus fumigatus
NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293
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