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AFUA_3G07970 AFUA_3G07970 AFUA_4G12850 AFUA_4G12850 AFUA_2G08300 AFUA_2G08300 AFUA_2G08620 AFUA_2G08620 AFUA_2G08650 AFUA_2G08650 AFUA_2G09170 AFUA_2G09170 AFUA_2G09240 AFUA_2G09240 AFUA_2G11040 AFUA_2G11040 AFUA_2G11440 AFUA_2G11440 AFUA_2G12060 AFUA_2G12060 AFUA_2G13310 AFUA_2G13310 AFUA_2G13690 AFUA_2G13690 sconB sconB AFUA_2G15070 AFUA_2G15070 AFUA_2G15890 AFUA_2G15890 AFUA_2G16030 AFUA_2G16030 AFUA_1G14690 AFUA_1G14690 AFUA_1G04490 AFUA_1G04490 AFUA_2G16470 AFUA_2G16470 AFUA_3G11870 AFUA_3G11870 AFUA_3G11390 AFUA_3G11390 AFUA_3G11300 AFUA_3G11300 AFUA_3G09090 AFUA_3G09090 AFUA_3G08940 AFUA_3G08940 AFUA_3G08280 AFUA_3G08280 AFUA_3G07820 AFUA_3G07820 AFUA_3G06910 AFUA_3G06910 AFUA_3G06200 AFUA_3G06200 AFUA_3G06110 AFUA_3G06110 AFUA_3G05950 AFUA_3G05950 AFUA_3G05550 AFUA_3G05550 AFUA_5G13730 AFUA_5G13730 AFUA_5G12680 AFUA_5G12680 AFUA_5G11720 AFUA_5G11720 AFUA_5G09200 AFUA_5G09200 AFUA_5G08370 AFUA_5G08370 AFUA_5G08130 AFUA_5G08130 AFUA_5G07960 AFUA_5G07960 AFUA_5G07050 AFUA_5G07050 AFUA_5G07040 AFUA_5G07040 pbn1 pbn1 AFUA_5G06370 AFUA_5G06370 sconC sconC AFUA_5G06040 AFUA_5G06040 AFUA_5G05790 AFUA_5G05790 fyv10 fyv10 hulA hulA AFUA_1G09830 AFUA_1G09830 AFUA_1G10950 AFUA_1G10950 AFUA_1G13920 AFUA_1G13920 AFUA_1G14320 AFUA_1G14320 mns1B mns1B AFUA_1G14730 AFUA_1G14730 ssh4 ssh4 AFUA_1G15710 AFUA_1G15710 AFUA_1G15770 AFUA_1G15770 AFUA_1G15920 AFUA_1G15920 AFUA_4G13170 AFUA_4G13170 AFUA_4G12110 AFUA_4G12110 AFUA_4G11440 AFUA_4G11440 AFUA_4G11160 AFUA_4G11160 AFUA_4G10780 AFUA_4G10780 AFUA_4G10570 AFUA_4G10570 AFUA_4G10070 AFUA_4G10070 AFUA_4G08480 AFUA_4G08480 AFUA_4G07510 AFUA_4G07510 AFUA_4G07430 AFUA_4G07430 AFUA_4G07420 AFUA_4G07420 AFUA_4G07340 AFUA_4G07340 AFUA_4G07330 AFUA_4G07330 sts1 sts1 AFUA_4G06960 AFUA_4G06960 sec13 sec13 AFUA_6G06350 AFUA_6G06350 AFUA_6G06450 AFUA_6G06450 AFUA_6G06540 AFUA_6G06540 AFUA_6G06780 AFUA_6G06780 AFUA_6G06790 AFUA_6G06790 AFUA_6G07760 AFUA_6G07760 AFUA_6G08310 AFUA_6G08310 AFUA_6G08420 AFUA_6G08420 AFUA_6G08880 AFUA_6G08880 AFUA_6G08960 AFUA_6G08960 AFUA_6G09160 AFUA_6G09160 AFUA_6G11400 AFUA_6G11400 AFUA_6G12360 AFUA_6G12360 AFUA_6G13030 AFUA_6G13030 AFUA_6G13170 AFUA_6G13170 AFUA_6G14120 AFUA_6G14120 AFUA_6G14130 AFUA_6G14130 ubc2 ubc2 AFUA_1G02430 AFUA_1G02430 npl4 npl4 AFUA_1G04210 AFUA_1G04210 AFUA_1G05180 AFUA_1G05180 AFUA_1G06170 AFUA_1G06170 AFUA_1G06850 AFUA_1G06850 AFUA_1G07050 AFUA_1G07050 AFUA_1G07540 AFUA_1G07540 AFUA_2G02860 AFUA_2G02860 AFUA_2G03170 AFUA_2G03170 AFUA_2G03400 AFUA_2G03400 AFUA_2G04620 AFUA_2G04620 AFUA_2G04910 AFUA_2G04910 AFUA_2G05210 AFUA_2G05210 AFUA_2G05440 AFUA_2G05440 AFUA_2G06330 AFUA_2G06330 AFUA_7G05870 AFUA_7G05870 AFUA_7G04650 AFUA_7G04650 AFUA_7G04320 AFUA_7G04320 AFUA_5G04060 AFUA_5G04060 lcl2 lcl2 AFUA_5G03610 AFUA_5G03610 AFUA_5G02930 AFUA_5G02930 AFUA_5G02590 AFUA_5G02590 AFUA_5G02440 AFUA_5G02440 AFUA_5G02400 AFUA_5G02400 AFUA_5G02150 AFUA_5G02150 AFUA_6G04790 AFUA_6G04790 fes1 fes1 AFUA_6G04670 AFUA_6G04670 AFUA_6G02380 AFUA_6G02380 AFUA_8G03960 AFUA_8G03960 yos9 yos9 AFUA_8G04840 AFUA_8G04840 AFUA_7G02290 AFUA_7G02290 AFUA_7G02110 AFUA_7G02110 AFUA_7G02000 AFUA_7G02000 AFUA_7G01390 AFUA_7G01390 AFUA_7G01380 AFUA_7G01380 AFUA_4G04280 AFUA_4G04280 AFUA_4G04640 AFUA_4G04640 AFUA_4G04660 AFUA_4G04660 AFUA_2G17110 AFUA_2G17110 AFUA_1G11410 AFUA_1G11410 AFUA_4G04612 AFUA_4G04612 AFUA_1G06080 AFUA_1G06080
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AFUA_3G07970Uncharacterized protein. (428 aa)
AFUA_4G12850Calnexin homolog; Interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins (By similarity). Belongs to the calreticulin family. (563 aa)
AFUA_2G08300DnaJ domain protein, putative. (427 aa)
AFUA_2G0862020S cyclosome subunit (BimA/Nuc2/Cdc27), putative. (809 aa)
AFUA_2G08650RING finger membrane protein. (1617 aa)
AFUA_2G09170DUF814 domain protein, putative. (1116 aa)
AFUA_2G09240F-box protein (Pof7), putative. (550 aa)
AFUA_2G11040U-box domain protein, putative. (284 aa)
AFUA_2G11440Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (250 aa)
AFUA_2G12060F-box and WD repeat-containing protein. (651 aa)
AFUA_2G13310RING finger domain protein, putative. (444 aa)
AFUA_2G13690Ubiquitin conjugating enzyme, putative. (157 aa)
sconBProbable E3 ubiquitin ligase complex SCF subunit sconB; Component of the SCF(sconB) E3 ubiquitin ligase complex involved in the regulation of sulfur metabolite repression, probably by mediating the inactivation or degradation of the metR transcription factor. (696 aa)
AFUA_2G1507026S proteasome regulatory subunit S5A. (280 aa)
AFUA_2G15890RING finger protein, putative. (751 aa)
AFUA_2G16030WD repeat protein. (712 aa)
AFUA_1G14690Ubiquitin-protein ligase Sel1/Ubx2, putative. (852 aa)
AFUA_1G04490Regulator of gluconeogenesis Rmd5, putative. (408 aa)
AFUA_2G16470Ubiquitin conjugating enzyme (UbcF), putative. (312 aa)
AFUA_3G11870F-box and WD40 domain protein, putative. (680 aa)
AFUA_3G11390Proteasome regulatory particle subunit Rpt3, putative; Belongs to the AAA ATPase family. (465 aa)
AFUA_3G11300Proteasome endopeptidase complex. (258 aa)
AFUA_3G09090RING finger domain protein. (380 aa)
AFUA_3G08940Proteasome regulatory particle subunit (RpnL), putative. (280 aa)
AFUA_3G08280Cell cycle regulatory protein (Srw1), putative. (603 aa)
AFUA_3G07820Proteasome regulatory particle subunit Rpt1, putative; Belongs to the AAA ATPase family. (439 aa)
AFUA_3G06910WD repeat protein. (656 aa)
AFUA_3G06200Anaphase-promoting complex subunit Apc5, putative. (768 aa)
AFUA_3G06110Proteasome regulatory particle subunit (RpnC), putative. (638 aa)
AFUA_3G0595020S cyclosome subunit (APC1/BimE), putative. (2080 aa)
AFUA_3G05550OTU-like cysteine protease, putative. (340 aa)
AFUA_5G13730NlpC/P60-like cell-wall peptidase, putative. (359 aa)
AFUA_5G12680Ubiquitin ligase subunit CulD, putative; Belongs to the cullin family. (911 aa)
AFUA_5G1172026S proteasome regulatory subunit RPN1; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. (905 aa)
AFUA_5G09200Ubiquitin conjugating enzyme (UbcC), putative; Belongs to the ubiquitin-conjugating enzyme family. (229 aa)
AFUA_5G08370Polyubiquitin binding protein (Doa1/Ufd3), putative. (790 aa)
AFUA_5G08130Protein transport protein Sec61 alpha subunit, putative. (478 aa)
AFUA_5G07960C2H2 finger and ankyrin domain protein, putative. (642 aa)
AFUA_5G07050Proteasome regulatory particle subunit Rpt2, putative; Belongs to the AAA ATPase family. (508 aa)
AFUA_5G07040Ubiquitin conjugating enzyme (UbcA), putative; Belongs to the ubiquitin-conjugating enzyme family. (272 aa)
pbn1Protein pbn1; Required for proper folding and/or the stability of a subset of proteins in the endoplasmic reticulum. Component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase gpi14 (By similarity). (489 aa)
AFUA_5G06370WHIM1 domain-containing protein. (580 aa)
sconCE3 ubiquitin ligase complex SCF subunit sconC; Essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Controls sulfur metabolite repression, probably by mediating the inactivation or degradation of the metR transcription factor (By similarity). (158 aa)
AFUA_5G06040UV excision repair protein (RadW), putative. (376 aa)
AFUA_5G05790Ubiquitin ligase subunit HrtA, putative. (120 aa)
fyv10Protein fyv10; Involved in the proteasome-dependent degradation of fructose- 1,6-bisphosphatase; Belongs to the FYV10 family. (411 aa)
hulAProbable E3 ubiquitin-protein ligase hulA; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Probably involved in the regulatory network controlling carbon source utilization. (813 aa)
AFUA_1G09830Hsc70 cochaperone (SGT), putative. (341 aa)
AFUA_1G10950Vesicle-mediated transport protein Vid24, putative. (330 aa)
AFUA_1G13920RING zinc finger protein, putative. (1643 aa)
AFUA_1G14320UBX domain protein. (514 aa)
mns1BProbable mannosyl-oligosaccharide alpha-1,2-mannosidase 1B; Involved in the maturation of Asn-linked oligosaccharides. Progressively trims alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2) (By similarity). (493 aa)
AFUA_1G14730Cell division cycle protein Cdc20, putative. (619 aa)
ssh4Protein ssh4; Components of the endosome-vacuole trafficking pathway that regulates nutrient transport. May be involved in processes which determine whether plasma membrane proteins are degraded or routed to the plasma membrane (By similarity); Belongs to the SSH4 family. (507 aa)
AFUA_1G15710Anaphase-promoting complex component Cut20/Apc4, putative. (735 aa)
AFUA_1G15770Anaphase promoting complex subunit 10 (APC10), putative. (454 aa)
AFUA_1G15920Ubiquitin carboxyl-terminal hydrolase. (316 aa)
AFUA_4G13170G-protein comlpex beta subunit CpcB. (316 aa)
AFUA_4G12110TPR domain protein. (400 aa)
AFUA_4G11440F-box and WD domain protein. (879 aa)
AFUA_4G11160Cell division control protein Cdc31, putative. (258 aa)
AFUA_4G10780Ubiquitin-protein ligase (Tom1), putative. (4037 aa)
AFUA_4G10570Cell cycle regulatory protein, putative. (877 aa)
AFUA_4G10070alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (641 aa)
AFUA_4G0848026S proteasome regulatory subunit RPN2; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. (1140 aa)
AFUA_4G07510Proteasome subunit beta. (212 aa)
AFUA_4G07430UBX domain protein, putative. (519 aa)
AFUA_4G07420Proteasome component Pup3, putative. (192 aa)
AFUA_4G07340Ubiquitin fusion degradation protein UfdB, putative. (1088 aa)
AFUA_4G07330ER associated DnaJ chaperone (Hlj1), putative. (376 aa)
sts1Tethering factor for nuclear proteasome sts1; Involved in ubiquitin-mediated protein degradation. Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates. Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins (By similarity). (312 aa)
AFUA_4G06960UBX domain protein, putative. (306 aa)
sec13Protein transport protein sec13; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. It also functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport facto [...] (306 aa)
AFUA_6G06350Proteasome endopeptidase complex. (278 aa)
AFUA_6G06450Proteasome subunit beta; Belongs to the peptidase T1B family. (260 aa)
AFUA_6G06540Proteasome component (Ecm29), putative. (1843 aa)
AFUA_6G06780Proteasome regulatory particle subunit Rpt4, putative; Belongs to the AAA ATPase family. (393 aa)
AFUA_6G06790alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (704 aa)
AFUA_6G07760Proteasome regulatory particle subunit (RpnG), putative. (492 aa)
AFUA_6G08310Proteasome component Pre2, putative. (296 aa)
AFUA_6G08420E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (2150 aa)
AFUA_6G08880Ubiquitin-protein ligase Ufd4, putative. (1817 aa)
AFUA_6G08960Proteasome subunit alpha type. (255 aa)
AFUA_6G09160Ubiquitin conjugating enzyme Ubc8, putative; Belongs to the ubiquitin-conjugating enzyme family. (202 aa)
AFUA_6G11400F-box and WD domain protein. (1069 aa)
AFUA_6G12360alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (893 aa)
AFUA_6G13030Cell division control protein Cdc4, putative. (1079 aa)
AFUA_6G13170Ubiquitin conjugating enzyme (UbcK), putative; Belongs to the ubiquitin-conjugating enzyme family. (181 aa)
AFUA_6G14120Uncharacterized protein. (373 aa)
AFUA_6G14130Ubiquitin conjugating enzyme, putative; Belongs to the ubiquitin-conjugating enzyme family. (168 aa)
ubc2Ubiquitin-conjugating enzyme E2 2; Catalyzes the covalent attachment of ubiquitin to other proteins. Plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation. Also involved in postreplication repair of UV-damaged DNA, in N-end rule-dependent protein degradation and in sporulation; Belongs to the ubiquitin-conjugating enzyme family. (151 aa)
AFUA_1G02430Ubiquitin fusion degradation protein Ufd1, putative. (384 aa)
npl4Nuclear protein localization protein 4; Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity); Belongs to the NPL4 family. (652 aa)
AFUA_1G04210IQ and HECT domain protein. (1225 aa)
AFUA_1G05180N-acetyltransferase (Nat5), putative. (190 aa)
AFUA_1G06170Proteasome regulatory particle subunit Rpt5, putative; Belongs to the AAA ATPase family. (464 aa)
AFUA_1G06850Nulp1-pending protein. (728 aa)
AFUA_1G07050Armadillo repeat protein. (993 aa)
AFUA_1G0754026S proteasome regulatory particle subunit Rpn8, putative. (350 aa)
AFUA_2G02860F-box domain protein. (727 aa)
AFUA_2G03170Cyclic nucleotide-binding domain protein. (900 aa)
AFUA_2G03400Proteasome regulatory particle subunit (RpnK), putative. (335 aa)
AFUA_2G04620Hsp70 chaperone BiP/Kar2, putative; Belongs to the heat shock protein 70 family. (672 aa)
AFUA_2G04910Proteasome component Pup1, putative. (272 aa)
AFUA_2G05210Anaphase-promoting complex subunit ApcB, putative; Belongs to the cullin family. (894 aa)
AFUA_2G05440CTLH domain-containing protein. (229 aa)
AFUA_2G06330Ubiquitin carboxyl-terminal hydrolase. (696 aa)
AFUA_7G05870Proteasome subunit alpha type. (282 aa)
AFUA_7G04650Proteasome subunit beta. (221 aa)
AFUA_7G04320UBX domain protein (Ubx5), putative. (527 aa)
AFUA_5G04060Ubiquitin conjugating enzyme (UbcH), putative; Belongs to the ubiquitin-conjugating enzyme family. (166 aa)
lcl2Long chronological lifespan protein 2; Probable component of the endoplasmic reticulum-associated degradation (ERAD) pathway. (122 aa)
AFUA_5G03610Cdc48-dependent protein degradation adaptor protein (Shp1), putative. (394 aa)
AFUA_5G02930Lysophospholipase, putative. (560 aa)
AFUA_5G0259020S cyclosome subunit (Cut9/Cdc16), putative. (621 aa)
AFUA_5G0244020S cyclosome subunit (APC8), putative. (689 aa)
AFUA_5G02400Catabolite degradation protein, putative. (374 aa)
AFUA_5G02150Proteasome endopeptidase complex. (251 aa)
AFUA_6G04790Proteasome subunit alpha type. (262 aa)
fes1Hsp70 nucleotide exchange factor fes1; Functions as a nucleotide exchange factor (NEF) for Hsp70 chaperones which accelerates the release of ADP. Required for fully efficient Hsp70-mediated folding of proteins (By similarity). Belongs to the FES1 family. (216 aa)
AFUA_6G04670Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (249 aa)
AFUA_6G02380Ubiquitin carboxyl-terminal hydrolase. (571 aa)
AFUA_8G03960Uncharacterized protein. (78 aa)
yos9Protein OS-9 homolog; Lectin involved in the quality control of the secretory pathway. As a member of the endoplasmic reticulum-associated degradation lumenal (ERAD-L) surveillance system, targets misfolded endoplasmic reticulum lumenal glycoproteins for degradation (By similarity). (520 aa)
AFUA_8G04840RING finger protein. (771 aa)
AFUA_7G02290alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (1080 aa)
AFUA_7G02110Ran-binding protein (RanBP10), putative. (697 aa)
AFUA_7G02000Leucine Rich Repeat domain protein. (384 aa)
AFUA_7G01390Uncharacterized protein. (383 aa)
AFUA_7G01380Anaphase promoting complex subunit Apc11, putative. (105 aa)
AFUA_4G04280AN1 zinc finger protein. (312 aa)
AFUA_4G04640Ubiquitin fusion degradation protein (Ufd1), putative. (795 aa)
AFUA_4G04660Proteasome regulatory particle subunit Rpt6, putative; Belongs to the AAA ATPase family. (389 aa)
AFUA_2G17110Cell division control protein Cdc48; Belongs to the AAA ATPase family. (819 aa)
AFUA_1G11410Ubiquitin conjugating enzyme E2, putative; Belongs to the ubiquitin-conjugating enzyme family. (427 aa)
AFUA_4G04612Ubiquitin-conjugating enzyme Ubc6, putative. (307 aa)
AFUA_1G06080BAG domain protein. (393 aa)
Your Current Organism:
Aspergillus fumigatus
NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293
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