STRINGSTRING
AFUA_2G00130 AFUA_2G00130 AFUA_2G10830 AFUA_2G10830 AFUA_2G12390 AFUA_2G12390 AFUA_2G13540 AFUA_2G13540 AFUA_2G15180 AFUA_2G15180 AFUA_2G16920 AFUA_2G16920 AFUA_3G12250 AFUA_3G12250 AFUA_3G11390 AFUA_3G11390 AFUA_3G10700 AFUA_3G10700 AFUA_3G10590 AFUA_3G10590 AFUA_3G09900 AFUA_3G09900 AFUA_3G08540 AFUA_3G08540 AFUA_3G07590 AFUA_3G07590 AFUA_3G07480 AFUA_3G07480 dhh1 dhh1 AFUA_5G14060 AFUA_5G14060 AFUA_5G13570 AFUA_5G13570 AFUA_5G13560 AFUA_5G13560 AFUA_5G11970 AFUA_5G11970 AFUA_5G10360 AFUA_5G10360 AFUA_5G08840 AFUA_5G08840 AFUA_5G07430 AFUA_5G07430 AFUA_5G05770 AFUA_5G05770 AFUA_1G09060 AFUA_1G09060 AFUA_1G09520 AFUA_1G09520 AFUA_1G09640 AFUA_1G09640 AFUA_1G12820 AFUA_1G12820 AFUA_1G13690 AFUA_1G13690 AFUA_1G14960 AFUA_1G14960 AFUA_4G13270 AFUA_4G13270 AFUA_4G13170 AFUA_4G13170 snx4 snx4 AFUA_4G12270 AFUA_4G12270 AFUA_4G08180 AFUA_4G08180 AFUA_6G06500 AFUA_6G06500 AFUA_6G06780 AFUA_6G06780 cap1 cap1 AFUA_6G10330 AFUA_6G10330 AFUA_6G13360 AFUA_6G13360 AFUA_1G02670 AFUA_1G02670 AFUA_1G02940 AFUA_1G02940 cap2 cap2 AFUA_1G04580 AFUA_1G04580 AFUA_1G04700 AFUA_1G04700 AFUA_1G04930 AFUA_1G04930 sar1 sar1 AFUA_1G04950 AFUA_1G04950 AFUA_1G05830 AFUA_1G05830 AFUA_1G06170 AFUA_1G06170 esa1 esa1 AFUA_2G05740 AFUA_2G05740 AFUA_2G06040 AFUA_2G06040 pob3 pob3 AFUA_7G03780 AFUA_7G03780 AFUA_7G03720 AFUA_7G03720 pxr1 pxr1 AFUA_3G00930 AFUA_3G00930 AFUA_3G01040 AFUA_3G01040 AFUA_3G02340 AFUA_3G02340 AFUA_5G04390 AFUA_5G04390 AFUA_5G02560 AFUA_5G02560 AFUA_5G01980 AFUA_5G01980 AFUA_5G01860 AFUA_5G01860 AFUA_6G04940 AFUA_6G04940 AFUA_6G02540 AFUA_6G02540 AFUA_6G02370 AFUA_6G02370 AFUA_6G02360 AFUA_6G02360 AFUA_8G03970 AFUA_8G03970 AFUA_8G05560 AFUA_8G05560 AFUA_8G05680 AFUA_8G05680 AFUA_8G05750 AFUA_8G05750 AFUA_8G02850 AFUA_8G02850 AFUA_4G03050 AFUA_4G03050 AFUA_4G04660 AFUA_4G04660 AFUA_6G00400 AFUA_6G00400 AFUA_1G12760 AFUA_1G12760 AFUA_5G08712 AFUA_5G08712
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AFUA_2G00130Solid-state culture specific protein, putative. (463 aa)
AFUA_2G10830Uncharacterized protein. (342 aa)
AFUA_2G12390Protein kinase regulator (Mob1), putative. (290 aa)
AFUA_2G13540CCCH zinc finger and RRM domain protein. (744 aa)
AFUA_2G15180Glutaredoxin domain-containing protein. (335 aa)
AFUA_2G16920Actin monomer binding protein, putative. (311 aa)
AFUA_3G12250Protein-tyrosine phosphatase, putative. (613 aa)
AFUA_3G11390Proteasome regulatory particle subunit Rpt3, putative; Belongs to the AAA ATPase family. (465 aa)
AFUA_3G10700Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (193 aa)
AFUA_3G10590Uncharacterized protein. (137 aa)
AFUA_3G09900GTPase activating protein Sar1, putative. (779 aa)
AFUA_3G08540Calcium binding modulator protein (Alg2), putative. (323 aa)
AFUA_3G07590ER-Golgi SNARE complex subunit (Sed5), putative. (346 aa)
AFUA_3G07480G-patch domain protein, putative. (722 aa)
dhh1ATP-dependent RNA helicase dhh1; ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping. Is involved in G1/S DNA-damage checkpoint recovery, probably through the regulation of the translational status of a subset of mRNAs. May also have a role in translation and mRNA nuclear export (By similarity); Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily. (507 aa)
AFUA_5G14060Rho GTPase Rho4, putative. (286 aa)
AFUA_5G13570Uncharacterized protein. (292 aa)
AFUA_5G13560FHA domain protein. (610 aa)
AFUA_5G11970Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (1106 aa)
AFUA_5G10360Actin-binding protein Fragmin, putative. (399 aa)
AFUA_5G08840Transcriptional regulator (Cti6), putative. (628 aa)
AFUA_5G07430Rho guanyl nucleotide exchange factor, putative. (1846 aa)
AFUA_5G057701,3-beta-glucan biosynthesis protein, putative. (515 aa)
AFUA_1G09060RXT2_N domain-containing protein. (512 aa)
AFUA_1G09520Uncharacterized protein. (390 aa)
AFUA_1G09640Actin-interacting protein (Bud6/Aip3), putative. (1055 aa)
AFUA_1G12820Spindle pole body component. (947 aa)
AFUA_1G13690WD repeat protein. (1298 aa)
AFUA_1G14960Gelsolin repeat protein, putative. (1637 aa)
AFUA_4G13270Unfolded protein response protein Orm1, putative. (186 aa)
AFUA_4G13170G-protein comlpex beta subunit CpcB. (316 aa)
snx4Sorting nexin-4; Sorting nexin, involved in the separation or division of vacuoles throughout the entire life cycle of the cells. Involved in retrieval of late-Golgi SNAREs from post-Golgi endosomes to the trans- Golgi network, for cytoplasm to vacuole transport (Cvt), mitophagy, and pexophagy (By similarity). (497 aa)
AFUA_4G12270LIM domain protein. (806 aa)
AFUA_4G08180RRN9 domain-containing protein. (606 aa)
AFUA_6G06500Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family. (363 aa)
AFUA_6G06780Proteasome regulatory particle subunit Rpt4, putative; Belongs to the AAA ATPase family. (393 aa)
cap1F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity). (276 aa)
AFUA_6G10330GTP binding protein (SPG1), putative. (389 aa)
AFUA_6G13360Uncharacterized protein. (1161 aa)
AFUA_1G02670Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (320 aa)
AFUA_1G02940Mitotic check point protein (Bub2), putative. (446 aa)
cap2F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity). (322 aa)
AFUA_1G04580Nitrogen permease regulator Npr2, putative. (584 aa)
AFUA_1G04700Ras guanyl-nucleotide exchange factor RasGEF, putative. (882 aa)
AFUA_1G04930Uncharacterized protein. (711 aa)
sar1Small COPII coat GTPase sar1; Small GTPase component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. Sar1 controls the coat assembly in a stepwise manner. Activated Sar1-GTP binds to membranes first and recruits the sec23/24 complex. These sec23/24-sar1 prebudding intermediates are then collected by the Sec13/31 complex as subunits polymerize to form coated trans [...] (189 aa)
AFUA_1G04950Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (323 aa)
AFUA_1G05830TBP associated factor (Mot1), putative. (1891 aa)
AFUA_1G06170Proteasome regulatory particle subunit Rpt5, putative; Belongs to the AAA ATPase family. (464 aa)
esa1Histone acetyltransferase esa1; Catalytic component of the NuA4 histone acetyltransferase (HAT) complex which is involved in epigenetic transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4, H3, H2B, H2A and H2A variant H2A.Z. Acetylates histone H4 to form H4K5ac, H4K8ac, H4K12ac and H4K16ac, histone H3 to form H3K14ac, histone H2B to form H2BK16ac, and histone H2A to form H2AK4ac and H2AK7ac. Acetylation of histone H4 is essential for DNA double- strand break repair through homologous recombination. Involved in cell cycle progression. Recru [...] (483 aa)
AFUA_2G05740Rho GTPase ModA, putative. (192 aa)
AFUA_2G06040Actin cortical patch component, putative. (577 aa)
pob3FACT complex subunit pob3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (573 aa)
AFUA_7G03780YT521-B-like splicing factor, putative. (546 aa)
AFUA_7G03720Serine/threonine protein kinase (Kin28), putative; Belongs to the protein kinase superfamily. (404 aa)
pxr1Protein pxr1; Involved in rRNA-processing at A0, A1 and A2 sites and regulates negatively telomerase; Belongs to the PINX1 family. (304 aa)
AFUA_3G00930C6 transcription factor, putative. (474 aa)
AFUA_3G01040Uncharacterized protein. (301 aa)
AFUA_3G02340CBF/NF-Y family transcription factor, putative. (142 aa)
AFUA_5G04390Cytokinesis regulator (Byr4), putative. (996 aa)
AFUA_5G02560Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (675 aa)
AFUA_5G01980Histone deacetylase HdaA. (602 aa)
AFUA_5G01860Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (188 aa)
AFUA_6G04940Cytokinesis protein SepA/Bni1. (1800 aa)
AFUA_6G02540Actin associated protein Wsp1, putative. (643 aa)
AFUA_6G02370Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (169 aa)
AFUA_6G02360Uncharacterized protein. (624 aa)
AFUA_8G03970C6 finger domain protein, putative. (901 aa)
AFUA_8G05560Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (497 aa)
AFUA_8G05680Serine/threonine-protein kinase. (1119 aa)
AFUA_8G05750C6 finger domain protein, putative. (409 aa)
AFUA_8G02850Actin binding protein, putative. (780 aa)
AFUA_4G03050Profilin; Belongs to the profilin family. (136 aa)
AFUA_4G04660Proteasome regulatory particle subunit Rpt6, putative; Belongs to the AAA ATPase family. (389 aa)
AFUA_6G00400Uncharacterized protein. (379 aa)
AFUA_1G12760Adenylyl cyclase-associated protein; Belongs to the CAP family. (526 aa)
AFUA_5G08712zf-C3H1 domain-containing protein. (1305 aa)
Your Current Organism:
Aspergillus fumigatus
NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293
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