STRINGSTRING
nde1 nde1 AFUA_5G11810 AFUA_5G11810 nudF nudF AFUA_1G04850 AFUA_1G04850 AFUA_1G04920 AFUA_1G04920 AFUA_2G05070 AFUA_2G05070 AFUA_8G04660 AFUA_8G04660 AFUA_2G13450 AFUA_2G13450
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
nde1Nuclear distribution protein nudE homolog 1; Required for nuclear migration within hyphae during vegetative growth. (621 aa)
AFUA_5G11810Dynein heavy chain. (4368 aa)
nudFNuclear distribution protein nudF; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family. (467 aa)
AFUA_1G04850Dynein light chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures. (94 aa)
AFUA_1G04920Calmodulin-binding protein Sha1, putative. (1015 aa)
AFUA_2G05070Uncharacterized protein. (506 aa)
AFUA_8G04660Noc1p protein, putative. (679 aa)
AFUA_2G13450Dynactin, putative. (1378 aa)
Your Current Organism:
Aspergillus fumigatus
NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293
Server load: low (22%) [HD]