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AFUA_6G14040 AFUA_6G14040 gda1 gda1 pmi1 pmi1 alg10 alg10 AFUA_2G11240 AFUA_2G11240 AFUA_2G14740 AFUA_2G14740 AFUA_2G14910 AFUA_2G14910 AFUA_2G16470 AFUA_2G16470 AFUA_2G16790 AFUA_2G16790 AFUA_2G17320 AFUA_2G17320 AFUA_3G14190 AFUA_3G14190 AFUA_3G10850 AFUA_3G10850 AFUA_3G10400 AFUA_3G10400 AFUA_3G07910 AFUA_3G07910 AFUA_3G07700 AFUA_3G07700 AFUA_3G07220 AFUA_3G07220 AFUA_3G06450 AFUA_3G06450 AFUA_5G13210 AFUA_5G13210 AFUA_5G13070 AFUA_5G13070 AFUA_5G12160 AFUA_5G12160 alg3 alg3 AFUA_5G11010 AFUA_5G11010 AFUA_5G10760 AFUA_5G10760 AFUA_5G08970 AFUA_5G08970 AFUA_5G08580 AFUA_5G08580 AFUA_5G08210 AFUA_5G08210 pbn1 pbn1 smp3 smp3 AFUA_1G09890 AFUA_1G09890 AFUA_1G12630 AFUA_1G12630 AFUA_1G13870 AFUA_1G13870 AFUA_1G14140 AFUA_1G14140 mns1B mns1B AFUA_4G14350 AFUA_4G14350 AFUA_4G14090 AFUA_4G14090 alg13 alg13 AFUA_4G12900 AFUA_4G12900 AFUA_4G11350 AFUA_4G11350 gpi18 gpi18 AFUA_4G10750 AFUA_4G10750 AFUA_4G09390 AFUA_4G09390 gpi10 gpi10 AFUA_4G08660 AFUA_4G08660 AFUA_4G06870 AFUA_4G06870 AFUA_6G06580 AFUA_6G06580 alg14 alg14 AFUA_6G14180 AFUA_6G14180 AFUA_6G14480 AFUA_6G14480 AFUA_1G01620 AFUA_1G01620 AFUA_1G02560 AFUA_1G02560 AFUA_1G03020 AFUA_1G03020 AFUA_1G03380 AFUA_1G03380 AFUA_1G03790 AFUA_1G03790 AFUA_1G03810 AFUA_1G03810 AFUA_1G05300 AFUA_1G05300 AFUA_1G05470 AFUA_1G05470 AFUA_1G06890 AFUA_1G06890 AFUA_1G07690 AFUA_1G07690 AFUA_2G01450 AFUA_2G01450 atg26 atg26 AFUA_2G02360 AFUA_2G02360 AFUA_2G05790 AFUA_2G05790 AFUA_2G06280 AFUA_2G06280 AFUA_2G06290 AFUA_2G06290 AFUA_2G06300 AFUA_2G06300 AFUA_7G04880 AFUA_7G04880 AFUA_3G00170 AFUA_3G00170 AFUA_5G02740 AFUA_5G02740 AFUA_5G02600 AFUA_5G02600 AFUA_5G00580 AFUA_5G00580 AFUA_5G00240 AFUA_5G00240 AFUA_6G04680 AFUA_6G04680 AFUA_6G04450 AFUA_6G04450 AFUA_6G04240 AFUA_6G04240 AFUA_6G04210 AFUA_6G04210 AFUA_8G04430 AFUA_8G04430 AFUA_8G04500 AFUA_8G04500 AFUA_8G06750 AFUA_8G06750 AFUA_8G07260 AFUA_8G07260 AFUA_8G02800 AFUA_8G02800 gnt1 gnt1 AFUA_8G02040 AFUA_8G02040 AFUA_8G02020 AFUA_8G02020 gpi14 gpi14 AFUA_7G01280 AFUA_7G01280 AFUA_6G00550 AFUA_6G00550 AFUA_6G00520 AFUA_6G00520 mpg1 mpg1 AFUA_6G06340 AFUA_6G06340 AFUA_1G12970 AFUA_1G12970 AFUA_5G14315 AFUA_5G14315 AFUA_2G15910 AFUA_2G15910
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
AFUA_6G14040Glycosyl transferase, putative. (395 aa)
gda1Probable guanosine-diphosphatase; After transfer of sugars to endogenous macromolecular acceptors, the enzyme converts nucleoside diphosphates to nucleoside monophosphates which in turn exit the Golgi lumen in a coupled antiporter reaction, allowing entry of additional nucleotide sugar from the cytosol; Belongs to the GDA1/CD39 NTPase family. (503 aa)
pmi1Mannose-6-phosphate isomerase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. (457 aa)
alg10Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase; Adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol; Belongs to the ALG10 glucosyltransferase family. (614 aa)
AFUA_2G11240UDP-N-acetyl-glucosamine-1-P transferase Alg7, putative. (468 aa)
AFUA_2G14740DUF821 domain protein. (435 aa)
AFUA_2G14910Alpha-1,6-mannosyltransferase subunit, putative. (462 aa)
AFUA_2G16470Ubiquitin conjugating enzyme (UbcF), putative. (312 aa)
AFUA_2G16790Alpha-1,3-glucosyltransferase; Belongs to the ALG6/ALG8 glucosyltransferase family. (440 aa)
AFUA_2G17320Uncharacterized protein. (453 aa)
AFUA_3G14190DUF2236 domain-containing protein. (290 aa)
AFUA_3G10850DUF821 domain protein. (445 aa)
AFUA_3G10400Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins. (245 aa)
AFUA_3G07910UDP-glucose 4-epimerase, putative. (428 aa)
AFUA_3G07700Alpha-1,3-glucosyltransferase; Belongs to the ALG6/ALG8 glucosyltransferase family. (593 aa)
AFUA_3G07220Uncharacterized protein. (443 aa)
AFUA_3G06450Protein mannosyltransferase 1. (946 aa)
AFUA_5G13210Alpha-1,2-mannosyltransferase (Alg2), putative. (470 aa)
AFUA_5G13070Uncharacterized protein. (403 aa)
AFUA_5G12160Alpha-1,2-mannosyltransferase (Kre5), putative. (506 aa)
alg3Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase; Adds the first Dol-P-Man derived mannose in an alpha-1,3 linkage to Man(5)GlcNAc(2)-PP-Dol; Belongs to the ALG3 family. (419 aa)
AFUA_5G11010Nucleoside diphosphatase (Ynd1), putative; Belongs to the GDA1/CD39 NTPase family. (719 aa)
AFUA_5G10760Alpha-1,2-mannosyltransferase (Kre2), putative. (400 aa)
AFUA_5G08970Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] (462 aa)
AFUA_5G08580Alpha-1,6-mannosyltransferase subunit (Och1), putative. (425 aa)
AFUA_5G08210Dolichyl-phosphate beta-glucosyltransferase, putative. (421 aa)
pbn1Protein pbn1; Required for proper folding and/or the stability of a subset of proteins in the endoplasmic reticulum. Component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase gpi14 (By similarity). (489 aa)
smp3GPI mannosyltransferase 4; Alpha-1,2-mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers a fourth mannose to trimannosyl-GPIs during GPI precursor assembly. The presence of a fourth mannose in GPI is essential in fungi (By similarity). (547 aa)
AFUA_1G09890Uncharacterized protein. (81 aa)
AFUA_1G12630Mannosylphosphate transferase (Mnn4), putative. (300 aa)
AFUA_1G13870Mannosyltransferase. (632 aa)
AFUA_1G14140GPI mannosyltransferase 2; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. (319 aa)
mns1BProbable mannosyl-oligosaccharide alpha-1,2-mannosidase 1B; Involved in the maturation of Asn-linked oligosaccharides. Progressively trims alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2) (By similarity). (493 aa)
AFUA_4G14350Kelch repeat protein. (578 aa)
AFUA_4G14090UDP-glucose 4-epimerase. (415 aa)
alg13UDP-N-acetylglucosamine transferase subunit alg13; Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway (By similarity). Belongs to the glycosyltransferase 28 family. (197 aa)
AFUA_4G12900Mannosyltransferase. (575 aa)
AFUA_4G11350Prenyltransferase, putative. (403 aa)
gpi18GPI mannosyltransferase 2; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the second mannose to the glycosylphosphatidylinositol during GPI precursor assembly (By similarity). (441 aa)
AFUA_4G10750Alpha-1,6-mannosyltransferase subunit, putative. (318 aa)
AFUA_4G09390DUF563 domain protein. (488 aa)
gpi10GPI mannosyltransferase 3; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the third mannose to Man2-GlcN-acyl-PI during GPI precursor assembly (By similarity). (771 aa)
AFUA_4G08660Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (289 aa)
AFUA_4G06870N-glycosyl-transferase. (411 aa)
AFUA_6G06580Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. (245 aa)
alg14UDP-N-acetylglucosamine transferase subunit alg14; Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway. Anchors the catalytic subunit alg13 to the ER (By similarity). (228 aa)
AFUA_6G14180Beta-1,4-mannosyltransferase (Alg1), putative. (461 aa)
AFUA_6G14480Alpha-1,3-mannosyltransferase, putative. (488 aa)
AFUA_1G01620CAP10 domain-containing protein. (772 aa)
AFUA_1G02560Uncharacterized protein. (253 aa)
AFUA_1G03020Dolichol phosphate-mannose biosynthesis regulatory protein; Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization. Belongs to the DPM2 family. (79 aa)
AFUA_1G03380UDP-N-acetylglucosaminyltransferase. (1634 aa)
AFUA_1G03790Mannosylphosphorylation protein (Mnn4), putative. (318 aa)
AFUA_1G03810Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] (189 aa)
AFUA_1G05300Capsular associated protein, putative. (979 aa)
AFUA_1G054703-oxo-5-alpha-steroid 4-dehydrogenase, putative. (311 aa)
AFUA_1G06890Alpha-1,2-mannosyltransferase (Alg11), putative. (560 aa)
AFUA_1G07690Protein O-mannosyl transferase. (759 aa)
AFUA_2G01450Alpha-1,6 mannosyltransferase subunit (Mnn9), putative. (397 aa)
atg26Sterol 3-beta-glucosyltransferase; Probable sterol 3-beta-glucosyltransferase that mediates autophagic degradation of peroxisomes (pexophagy) (By similarity). Also required for cytoplasm to vacuole transport (Cvt) and autophagic degradation of mitochondria (mitophagy) and nuclei (nucleophagy) (By similarity); Belongs to the glycosyltransferase 28 family. (1405 aa)
AFUA_2G02360UDP-glucose:glycoprotein glucosyltransferase, putative. (1487 aa)
AFUA_2G05790Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (504 aa)
AFUA_2G06280Oligosaccharyl transferase subunit (Gamma), putative. (325 aa)
AFUA_2G06290Oligosaccharide translocation protein RFT1; May participate in the translocation of oligosaccharide from the cytoplasmic side to the lumenal side of the endoplasmic reticulum membrane; Belongs to the RFT1 family. (261 aa)
AFUA_2G06300Oligosaccharide translocation protein RFT1; May participate in the translocation of oligosaccharide from the cytoplasmic side to the lumenal side of the endoplasmic reticulum membrane; Belongs to the RFT1 family. (277 aa)
AFUA_7G04880Sterol glucosyltransferase, putative. (787 aa)
AFUA_3G00170Uncharacterized protein. (331 aa)
AFUA_5G02740Alpha-1,2-mannosyltransferase (Ktr4), putative. (397 aa)
AFUA_5G02600CAP10 domain-containing protein. (464 aa)
AFUA_5G00580CAP10 domain-containing protein. (423 aa)
AFUA_5G00240Uncharacterized protein. (139 aa)
AFUA_6G04680MIPC synthase subunit (SurA), putative. (356 aa)
AFUA_6G04450Alpha-1,2-mannosyltransferase (Mnn2), putative. (493 aa)
AFUA_6G04240PAP2 domain protein. (214 aa)
AFUA_6G04210Mannosyl-oligosaccharide glucosidase, putative. (822 aa)
AFUA_8G04430Oligosaccharyl transferase subunit (Stt3), putative. (743 aa)
AFUA_8G04500Mannosyltransferase PMTI. (780 aa)
AFUA_8G06750UDP-glucose,sterol transferase, putative. (977 aa)
AFUA_8G07260Uncharacterized protein. (498 aa)
AFUA_8G02800Uncharacterized protein. (360 aa)
gnt1Glucose N-acetyltransferase 1; N-acetylglucosaminyltransferase involved in the Golgi- specific modification of N-linked glycans; Belongs to the GNT1 family. (384 aa)
AFUA_8G02040Glycosyl transferase, putative. (394 aa)
AFUA_8G02020Glycosyltransferase, putative. (717 aa)
gpi14GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly. Required for cell wall integrity (By similarity). (425 aa)
AFUA_7G01280DNA damage response protein RcaA. (704 aa)
AFUA_6G00550Glycosyl transferase family 8 family, putative. (375 aa)
AFUA_6G00520Uncharacterized protein. (438 aa)
mpg1Mannose-1-phosphate guanyltransferase; Involved in cell wall synthesis where it is required for glycosylation. Involved in cell cycle progression through cell-size checkpoint (By similarity); Belongs to the transferase hexapeptide repeat family. (364 aa)
AFUA_6G06340Glucosamine-fructose-6-phosphate aminotransferase. (694 aa)
AFUA_1G12970Cupin_2 domain-containing protein. (166 aa)
AFUA_5G14315Uncharacterized protein. (370 aa)
AFUA_2G15910Mannan polymerase II complex ANP1 subunit Anp1, putative. (446 aa)
Your Current Organism:
Aspergillus fumigatus
NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293
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