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| | AFUA_2G11430 | Spindle pole body component. (891 aa) |
| | AFUA_2G08990 | Eukaryotic translation initiation factor 5, putative. (421 aa) |
| | AFUA_2G09210 | 60S ribosomal protein L10. (223 aa) |
| | AFUA_2G10090 | 40S ribosomal protein S15, putative; Belongs to the universal ribosomal protein uS19 family. (153 aa) |
| | AFUA_2G10440 | 40S ribosomal protein S11; Belongs to the universal ribosomal protein uS11 family. (150 aa) |
| | AFUA_2G10980 | ADP-ribosylation factor, putative; Belongs to the small GTPase superfamily. Arf family. (182 aa) |
| | AFUA_5G13470 | Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (247 aa) |
| | AFUA_5G13360 | YjeF_N domain protein. (702 aa) |
| | AFUA_5G12570 | U6 small nuclear ribonucleoprotein (Lsm3), putative. (83 aa) |
| | AFUA_5G11970 | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (1106 aa) |
| | atg18 | Autophagy-related protein 18; The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Necessary for proper vacuole morphology. Plays an important role in osmotically-induced vacuole fragmentation. Required for cytoplasm to vacuole transport (Cvt) vesicle formation, pexophagy and starvation- induced autophagy. Involved in correct atg9 trafficking to the pre- autophagosomal structure. Might also be involved in premeiotic DNA replication (By similarity). (436 aa) |
| | AFUA_5G10770 | Topisomerase II associated protein (Pat1), putative. (827 aa) |
| | AFUA_5G08670 | Phosphatidylinositol 3-kinase VPS34. (898 aa) |
| | AFUA_5G08530 | Phosphatidylinositol 3,5-bisphosphate-binding protein, putative. (258 aa) |
| | atg3 | Autophagy-related protein 3; E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt) and autophagy. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C- terminal Gly of atg8. The atg12-atg5 conjugate plays a role of an E3 and promotes the transfer of [...] (353 aa) |
| | AFUA_5G07390 | 60S ribosome biogenesis protein Sqt1, putative. (515 aa) |
| | AFUA_5G06510 | Ribosome biogenesis GTPase Lsg1, putative. (676 aa) |
| | AFUA_5G06310 | Uncharacterized protein. (216 aa) |
| | TIF6 | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family. (247 aa) |
| | AFUA_5G05900 | Non-specific serine/threonine protein kinase. (836 aa) |
| | AFUA_5G05630 | 60S ribosomal protein L23. (144 aa) |
| | AFUA_1G08850 | Septin; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (346 aa) |
| | AFUA_1G08970 | Uncharacterized protein. (441 aa) |
| | AFUA_1G09630 | PAB1 binding protein (Pbp1), putative. (980 aa) |
| | AFUA_1G09850 | 37S ribosomal protein S11, putative. (198 aa) |
| | AFUA_1G10690 | M protein repeat protein. (878 aa) |
| | AFUA_1G11130 | 60S ribosomal protein L6. (200 aa) |
| | AFUA_1G12000 | Nuclear and cytoplasmic polyadenylated RNA-binding protein pub1. (489 aa) |
| | stu1 | Protein stu1; Microtubule binding protein that promotes the stabilization of dynamic microtubules. Required for mitotic spindle formation (By similarity). (1344 aa) |
| | AFUA_1G12890 | 60S ribosomal protein L5, putative. (308 aa) |
| | drs1 | ATP-dependent RNA helicase drs1; ATP-binding RNA helicase involved in ribosome assembly. (830 aa) |
| | AFUA_1G15020 | 40S ribosomal protein S5, putative; Belongs to the universal ribosomal protein uS7 family. (231 aa) |
| | AFUA_1G16540 | WD40 domain protein. (479 aa) |
| | atg1 | Serine/threonine-protein kinase atg1; Serine/threonine protein kinase involved in the cytoplasm to vacuole transport (Cvt) and found to be essential in autophagy, where it is required for the formation of autophagosomes. Involved in the clearance of protein aggregates which cannot be efficiently cleared by the proteasome. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing [...] (973 aa) |
| | AFUA_4G07200 | Uncharacterized protein. (781 aa) |
| | AFUA_4G06540 | CHL4 family chromosome segregation protein, putative. (470 aa) |
| | atg5 | Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy). Also required for mitophagy, which eliminates defective or superfluous mitochondria in order to fulfill cellular energy requirements and prevent excess ROS production. Conjugation with atg12, through a ubiquitin-like conjugating system involving atg7 as an E1- like activating enzyme and atg10 as an E2- [...] (326 aa) |
| | atg9 | Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Required for mitophagy. Cycles between the PAS and the cytoplasmic vesicle pool and may participate in supplying membrane for the growing autophagosome. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. Different machinerie [...] (951 aa) |
| | atg2 | Autophagy-related protein 2; Required for cytoplasm to vacuole transport (Cvt) vesicles and autophagosomes completion and peroxisome degradation. Belongs to the ATG2 family. (2160 aa) |
| | AFUA_6G13530 | UPF0023 family protein. (344 aa) |
| | AFUA_1G01140 | Uncharacterized protein. (252 aa) |
| | AFUA_1G01990 | Ribosome biogenesis protein Rsa4, putative. (515 aa) |
| | AFUA_1G02200 | F-box domain protein. (357 aa) |
| | AFUA_1G02210 | 60S ribosome biogenesis protein Brx1, putative. (376 aa) |
| | AFUA_1G02270 | ARS binding protein Abp2, putative. (780 aa) |
| | mrd1 | Multiple RNA-binding domain-containing protein 1; Involved in pre-rRNA processing; Belongs to the RRM MRD1 family. (825 aa) |
| | AFUA_1G05000 | Uncharacterized protein. (139 aa) |
| | AFUA_1G05080 | 60S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10. (313 aa) |
| | AFUA_1G05340 | 40S ribosomal protein S19. (221 aa) |
| | AFUA_1G05870 | Inositol phospholipid biosynthesis protein Scs3, putative. (322 aa) |
| | AFUA_1G06230 | Ribosome biogenesis protein Ssf2, putative. (445 aa) |
| | AFUA_1G07090 | Uncharacterized protein. (1526 aa) |
| | AFUA_1G07270 | Uncharacterized protein. (78 aa) |
| | AFUA_1G07280 | Uncharacterized protein. (442 aa) |
| | AFUA_1G07590 | Cupin domain protein. (634 aa) |
| | AFUA_2G01830 | Uncharacterized protein; Belongs to the universal ribosomal protein uL22 family. (354 aa) |
| | AFUA_2G03400 | Proteasome regulatory particle subunit (RpnK), putative. (335 aa) |
| | AFUA_2G04210 | Uncharacterized protein. (256 aa) |
| | AFUA_3G11860 | Microtubule associated protein EB1, putative. (278 aa) |
| | rps0 | 40S ribosomal protein S0; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. (297 aa) |
| | esf2 | Pre-rRNA-processing protein esf2; Involved in the small subunit (SSU) processome assembly and function, and in the 18S rRNA synthesis. Required for the early cleavages at sites A0, A1 and A2 (By similarity); Belongs to the ESF2/ABP1 family. (361 aa) |
| | AFUA_2G16670 | Uncharacterized protein. (742 aa) |
| | AFUA_2G16260 | Microtubule associated protein (Ase1), putative. (768 aa) |
| | AFUA_2G16040 | rRNA biogenesis protein RRP5, putative. (1822 aa) |
| | AFUA_2G15750 | Spindle pole body component. (826 aa) |
| | AFUA_2G15570 | RAS small monomeric GTPase Rab6, putative. (207 aa) |
| | AFUA_2G14280 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (769 aa) |
| | atg17 | Autophagy-related protein 17; Autophagy-specific protein that functions in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize pre-autophagosomal structure (PAS) formation. Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles. Plays particularly a role in pexophagy and nucleophagy (By similarity); Belongs to the ATG17 family. (551 aa) |
| | AFUA_2G12150 | Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family. (4925 aa) |
| | LSM4 | U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (119 aa) |
| | AFUA_3G09030 | Regulatory protein SUAPRGA1. (354 aa) |
| | AFUA_3G08100 | Checkpoint protein kinase, putative. (841 aa) |
| | AFUA_3G07240 | Multidomain presynaptic cytomatrix related protein. (398 aa) |
| | AFUA_3G06980 | Uncharacterized protein. (304 aa) |
| | AFUA_3G06640 | 40S ribosomal protein S27. (82 aa) |
| | AFUA_3G06330 | CENP-T_C domain-containing protein. (480 aa) |
| | dhh1 | ATP-dependent RNA helicase dhh1; ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping. Is involved in G1/S DNA-damage checkpoint recovery, probably through the regulation of the translational status of a subset of mRNAs. May also have a role in translation and mRNA nuclear export (By similarity); Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily. (507 aa) |
| | vac8 | Vacuolar protein 8; Functions in both vacuole inheritance and protein targeting from the cytoplasm to vacuole; Belongs to the beta-catenin family. (578 aa) |
| | AFUA_5G13520 | Ribosome biogenesis protein Ria1, putative. (1087 aa) |
| | AFUA_3G09370 | Spindle-pole body protein (Pcp1), putative. (1271 aa) |
| | AFUA_3G09950 | Phospholipid:diacylglycerol acyltransferase, putative. (594 aa) |
| | AFUA_3G10230 | Uncharacterized protein. (388 aa) |
| | AFUA_3G11320 | Spindle pole body component. (1035 aa) |
| | atg11 | Autophagy-related protein 11; Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy. Recruits mitochondria for their selective degradation via autophagy (mitophagy) during starvation. Works as scaffold proteins that recruit ATG proteins to the pre-autophagosome (PAS), the site of vesicle/autophagosome formation. Required for the Cvt vesicles completion (By similarity). (1264 aa) |
| | atg12 | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy. Conjugation with atg5 through a ubiquitin-like conjugating system involving also atg7 as an E1-like activating enzyme and atg10 as an E2-like conjugating enzyme, is essential for its function. The atg12-atg5 conjugate functions as an E3-like enzyme which is required for lipidation of atg8 and atg8 association to the vesicle membranes (By similarity). (174 aa) |
| | AFUA_2G17060 | 60S ribosome subunit biogenesis protein NIP7; Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (185 aa) |
| | AFUA_1G12390 | G2/M phase checkpoint control protein Sum2, putative. (588 aa) |
| | AFUA_1G13390 | Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. (455 aa) |
| | AFUA_7G01400 | Kinesin family protein (BimC), putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1190 aa) |
| | AFUA_7G02210 | Ribosomal small subunit assembly protein, putative. (315 aa) |
| | AFUA_8G05680 | Serine/threonine-protein kinase. (1119 aa) |
| | AFUA_8G04790 | Ribosome biogenesis protein, putative. (330 aa) |
| | AFUA_8G04330 | Uncharacterized protein. (369 aa) |
| | AFUA_8G04140 | Uncharacterized protein. (772 aa) |
| | AFUA_5G02730 | Spindle pole body component. (888 aa) |
| | AFUA_5G03090 | Small nucleolar ribonucleoprotein complex subunit (Pwp2), putative. (926 aa) |
| | AFUA_5G03610 | Cdc48-dependent protein degradation adaptor protein (Shp1), putative. (394 aa) |
| | AFUA_5G04320 | Secretion related GTPase SrgB/Ypt1. (201 aa) |
| | AFUA_7G04490 | Ribosomal protein S28e. (56 aa) |
| | AFUA_2G06250 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...] (723 aa) |
| | rex4 | RNA exonuclease 4; Exoribonuclease involved in ribosome biosynthesis. Involved in the processing of ITS1, the internal transcribed spacer localized between the 18S and 5.8S rRNAs (By similarity); Belongs to the REXO4 family. (310 aa) |
| | AFUA_2G05550 | Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (430 aa) |
| | atg13 | Autophagy-related protein 13; Activates the atg1 kinase in a nutritional condition dependent manner through the TOR pathway, leading to autophagy. Also involved in cytoplasm to vacuole transport (Cvt) and more specifically in Cvt vesicle formation. Seems to play a role in the switching machinery regulating the conversion between the Cvt pathway and autophagy. Finally, atg13 is also required for glycogen storage during stationary phase (By similarity). (958 aa) |
| | ste20 | Serine/threonine-protein kinase ste20; MAP4K component of the MAPK pathway required for the mating pheromone response and the regulation of cell polarity and cell cycle. Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. (815 aa) |
| | AFUA_1G03710 | C2H2 finger domain protein, putative. (433 aa) |
| | AFUA_1G04280 | 30S ribosomal protein S7, putative. (354 aa) |
