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AFUA_1G06420 AFUA_1G06420 AFUA_1G13330 AFUA_1G13330 AFUA_6G11190 AFUA_6G11190 AFUA_4G04100 AFUA_4G04100 AFUA_4G03870 AFUA_4G03870 vps10 vps10 AFUA_6G02420 AFUA_6G02420 AFUA_5G02360 AFUA_5G02360 AFUA_3G04060 AFUA_3G04060 AFUA_7G03640 AFUA_7G03640 AFUA_2G05440 AFUA_2G05440 mon1 mon1 vps27 vps27 hse1 hse1 AFUA_1G06680 AFUA_1G06680 AFUA_4G11560 AFUA_4G11560 AFUA_4G12070 AFUA_4G12070 AFUA_4G12080 AFUA_4G12080 AFUA_4G12290 AFUA_4G12290 AFUA_1G16320 AFUA_1G16320 ssh4 ssh4 AFUA_1G10950 AFUA_1G10950 hulA hulA AFUA_5G11360 AFUA_5G11360 AFUA_5G13600 AFUA_5G13600 AFUA_5G13890 AFUA_5G13890 AFUA_3G05820 AFUA_3G05820 AFUA_3G08730 AFUA_3G08730 AFUA_3G10060 AFUA_3G10060 AFUA_3G10650 AFUA_3G10650 AFUA_3G10740 AFUA_3G10740 AFUA_3G11200 AFUA_3G11200 AFUA_3G12360 AFUA_3G12360 AFUA_3G12370 AFUA_3G12370 AFUA_3G14380 AFUA_3G14380 mvp1 mvp1 bro1 bro1 AFUA_2G10980 AFUA_2G10980
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AFUA_1G06420SNF7 family protein. (241 aa)
AFUA_1G13330Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (388 aa)
AFUA_6G11190Protein kinase (VPS15), putative. (1637 aa)
AFUA_4G04100Vacuolar protein sorting protein (Vps36), putative. (537 aa)
AFUA_4G03870Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (260 aa)
vps10Vacuolar protein sorting/targeting protein 10; Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A. Executes multiple rounds of sorting by cycling between the late Golgi and a prevacuolar endosome-like compartment (By similarity); Belongs to the VPS10-related sortilin family. (1487 aa)
AFUA_6G02420Ubiquitin conjugating enzyme (UbcM), putative; Belongs to the ubiquitin-conjugating enzyme family. (149 aa)
AFUA_5G02360Vacuolar dynamin-like GTPase VpsA, putative; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (698 aa)
AFUA_3G04060SNF7 family protein Fti1/Did2, putative. (209 aa)
AFUA_7G03640AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane. (953 aa)
AFUA_2G05440CTLH domain-containing protein. (229 aa)
mon1Vacuolar fusion protein mon1; Required for multiple vacuole delivery pathways including the cytoplasm to vacuole transport (Cvt), autophagy, pexophagy and endocytosis; Belongs to the MON1/SAND family. (621 aa)
vps27Vacuolar protein sorting-associated protein 27; Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane. (729 aa)
hse1Class E vacuolar protein-sorting machinery protein hse1; Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB). (584 aa)
AFUA_1G06680VHS domain protein. (642 aa)
AFUA_4G11560Vacuolar protein sorting-associated protein; May be involved in recycling of membrane proteins between an endocytic compartment and the TGN; Belongs to the VPS13 family. (3187 aa)
AFUA_4G12070Endosomal peripheral membrane protein (Mon2), putative. (1688 aa)
AFUA_4G12080Ubiquitin conjugating enzyme (MmsB), putative. (139 aa)
AFUA_4G12290ESCRT-II complex component (Vps25), putative. (195 aa)
AFUA_1G16320Vacuolar protein sorting-associated protein 28; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (244 aa)
ssh4Protein ssh4; Components of the endosome-vacuole trafficking pathway that regulates nutrient transport. May be involved in processes which determine whether plasma membrane proteins are degraded or routed to the plasma membrane (By similarity); Belongs to the SSH4 family. (507 aa)
AFUA_1G10950Vesicle-mediated transport protein Vid24, putative. (330 aa)
hulAProbable E3 ubiquitin-protein ligase hulA; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Probably involved in the regulatory network controlling carbon source utilization. (813 aa)
AFUA_5G11360AP-3 adaptor complex subunit beta, putative. (843 aa)
AFUA_5G13600Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology. (828 aa)
AFUA_5G13890SNF7 family protein. (229 aa)
AFUA_3G05820ZZ type zinc finger domain protein. (838 aa)
AFUA_3G08730Endosome-associated ubiquitin isopeptidase (AmsH), putative. (532 aa)
AFUA_3G10060Dor1-like family protein. (478 aa)
AFUA_3G10650Glutamate carboxypeptidase Tre2, putative. (907 aa)
AFUA_3G10740RAB GTPase Vps21/Ypt51, putative. (262 aa)
AFUA_3G11200Vacuolar assembly protein, putative. (1298 aa)
AFUA_3G12360Uncharacterized protein. (514 aa)
AFUA_3G12370V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (161 aa)
AFUA_3G14380Endosomal sorting complex protein TSG101, putative. (579 aa)
mvp1Sorting nexin mvp1; Required for vacuolar protein sorting. (729 aa)
bro1Vacuolar protein-sorting protein bro1; Involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles; Belongs to the BRO1 family. (976 aa)
AFUA_2G10980ADP-ribosylation factor, putative; Belongs to the small GTPase superfamily. Arf family. (182 aa)
Your Current Organism:
Aspergillus fumigatus
NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293
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