STRINGSTRING
AFUA_1G07180 AFUA_1G07180 AFUA_3G14160 AFUA_3G14160 AFUA_6G06530 AFUA_6G06530 AFUA_6G06535 AFUA_6G06535 AFUA_2G04535 AFUA_2G04535 AFUA_1G12475 AFUA_1G12475 AFUA_1G13570 AFUA_1G13570 AFUA_m0430 AFUA_m0430 mitF mitF AFUA_4G03820 AFUA_4G03820 AFUA_4G03230 AFUA_4G03230 dcl2 dcl2 AFUA_7G00870 AFUA_7G00870 AFUA_7G01330 AFUA_7G01330 AFUA_7G01550 AFUA_7G01550 AFUA_8G01900 AFUA_8G01900 AFUA_8G05430 AFUA_8G05430 AFUA_8G05280 AFUA_8G05280 USB1 USB1 AFUA_8G04820 AFUA_8G04820 AFUA_8G04640 AFUA_8G04640 AFUA_8G04420 AFUA_8G04420 AFUA_6G02160 AFUA_6G02160 AFUA_6G02270 AFUA_6G02270 AFUA_6G02530 AFUA_6G02530 AFUA_6G04350 AFUA_6G04350 rrp36 rrp36 rai1 rai1 AFUA_6G05310 AFUA_6G05310 AFUA_5G01600 AFUA_5G01600 AFUA_5G01800 AFUA_5G01800 AFUA_5G02030 AFUA_5G02030 AFUA_5G03090 AFUA_5G03090 AFUA_5G03120 AFUA_5G03120 AFUA_5G03320 AFUA_5G03320 slx1 slx1 AFUA_5G04000 AFUA_5G04000 AFUA_5G04010 AFUA_5G04010 AFUA_5G04070 AFUA_5G04070 AFUA_5G04440 AFUA_5G04440 AFUA_3G04110 AFUA_3G04110 AFUA_3G03050 AFUA_3G03050 AFUA_3G02450 AFUA_3G02450 AFUA_7G04270 AFUA_7G04270 AFUA_7G04430 AFUA_7G04430 AFUA_7G05280 AFUA_7G05280 AFUA_7G08520 AFUA_7G08520 dbp3 dbp3 AFUA_2G06220 AFUA_2G06220 AFUA_2G06090 AFUA_2G06090 rex4 rex4 AFUA_2G05480 AFUA_2G05480 pan2n2 pan2n2 AFUA_2G03740 AFUA_2G03740 rps21 rps21 AFUA_2G03340 AFUA_2G03340 slx4 slx4 AFUA_2G02960 AFUA_2G02960 AFUA_2G02400 AFUA_2G02400 AFUA_2G02340 AFUA_2G02340 grc3 grc3 AFUA_2G01900 AFUA_2G01900 AFUA_2G01330 AFUA_2G01330 NTH1 NTH1 AFUA_2G01110 AFUA_2G01110 AFUA_1G07600 AFUA_1G07600 AFUA_1G07510 AFUA_1G07510 AFUA_1G07090 AFUA_1G07090 AFUA_1G06380 AFUA_1G06380 AFUA_1G05410 AFUA_1G05410 AFUA_1G04950 AFUA_1G04950 mrd1 mrd1 AFUA_1G04570 AFUA_1G04570 AFUA_1G04240 AFUA_1G04240 lcl3 lcl3 yth1 yth1 AFUA_1G02680 AFUA_1G02680 AFUA_1G02610 AFUA_1G02610 AFUA_1G02210 AFUA_1G02210 AFUA_1G02200 AFUA_1G02200 AFUA_1G02060 AFUA_1G02060 AFUA_1G01720 AFUA_1G01720 AFUA_6G14460 AFUA_6G14460 ubc2 ubc2 AFUA_6G12140 AFUA_6G12140 AFUA_6G11410 AFUA_6G11410 AFUA_6G10900 AFUA_6G10900 fip1 fip1 AFUA_6G10370 AFUA_6G10370 AFUA_6G07850 AFUA_6G07850 AFUA_6G07500 AFUA_6G07500 pno1 pno1 AFUA_6G06380 AFUA_6G06380 AFUA_4G06260 AFUA_4G06260 AFUA_4G07010 AFUA_4G07010 AFUA_4G07160 AFUA_4G07160 AFUA_4G07290 AFUA_4G07290 AFUA_4G07500 AFUA_4G07500 AFUA_4G07540 AFUA_4G07540 AFUA_4G12200 AFUA_4G12200 AFUA_4G12210 AFUA_4G12210 AFUA_4G12250 AFUA_4G12250 AFUA_4G12670 AFUA_4G12670 AFUA_4G12680 AFUA_4G12680 ccr4 ccr4 ysh1 ysh1 AFUA_1G16600 AFUA_1G16600 AFUA_1G16470 AFUA_1G16470 AFUA_1G13910 AFUA_1G13910 AFUA_1G13850 AFUA_1G13850 AFUA_1G12730 AFUA_1G12730 AFUA_1G11420 AFUA_1G11420 AFUA_1G10020 AFUA_1G10020 AFUA_5G06150 AFUA_5G06150 AFUA_5G06830 AFUA_5G06830 AFUA_5G07370 AFUA_5G07370 AFUA_5G07850 AFUA_5G07850 AFUA_5G09250 AFUA_5G09250 AFUA_5G10820 AFUA_5G10820 AFUA_5G11140 AFUA_5G11140 AFUA_5G11150 AFUA_5G11150 AFUA_5G11550 AFUA_5G11550 dcl1 dcl1 AFUA_5G12250 AFUA_5G12250 AFUA_5G12420 AFUA_5G12420 AFUA_5G12640 AFUA_5G12640 AFUA_5G12860 AFUA_5G12860 AFUA_5G13220 AFUA_5G13220 AFUA_5G13360 AFUA_5G13360 AFUA_5G13530 AFUA_5G13530 AFUA_3G05860 AFUA_3G05860 fen1 fen1 AFUA_3G06160 AFUA_3G06160 AFUA_3G06180 AFUA_3G06180 AFUA_3G06380 AFUA_3G06380 AFUA_3G09050 AFUA_3G09050 pol2 pol2 AFUA_3G09720 AFUA_3G09720 AFUA_3G09880 AFUA_3G09880 AFUA_3G10290 AFUA_3G10290 AFUA_3G11010 AFUA_3G11010 nop9 nop9 rny1 rny1 AFUA_3G11820 AFUA_3G11820 rex3 rex3 mus81 mus81 AFUA_3G13260 AFUA_3G13260 nop58 nop58 AFUA_2G17230 AFUA_2G17230 AFUA_2G16960 AFUA_2G16960 AFUA_2G16830 AFUA_2G16830 esf2 esf2 AFUA_2G16710 AFUA_2G16710 AFUA_2G16600 AFUA_2G16600 AFUA_2G16130 AFUA_2G16130 AFUA_2G16040 AFUA_2G16040 AFUA_2G15220 AFUA_2G15220 AFUA_2G14950 AFUA_2G14950 AFUA_2G13650 AFUA_2G13650 AFUA_2G13570 AFUA_2G13570 AFUA_2G13340 AFUA_2G13340 AFUA_2G13130 AFUA_2G13130 AFUA_2G12890 AFUA_2G12890 AFUA_2G12880 AFUA_2G12880 AFUA_2G11770 AFUA_2G11770 AFUA_2G11380 AFUA_2G11380 AFUA_2G11070 AFUA_2G11070 AFUA_2G09100 AFUA_2G09100 AFUA_2G08860 AFUA_2G08860 AFUA_2G08750 AFUA_2G08750 AFUA_2G08540 AFUA_2G08540 rat1 rat1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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AFUA_1G07180Ribonuclease H, putative. (410 aa)
AFUA_3G14160Uncharacterized protein. (170 aa)
AFUA_6G06530Uncharacterized protein. (249 aa)
AFUA_6G06535Uncharacterized protein. (192 aa)
AFUA_2G04535Uncharacterized protein. (497 aa)
AFUA_1G12475Uncharacterized protein. (145 aa)
AFUA_1G13570Small nuclear ribonucleoprotein complex protein Nhp2, putative. (323 aa)
AFUA_m0430Intron-encoded LAGLIDADG endonuclease family protein. (291 aa)
mitFRibonuclease mitogillin; This purine-specific ribonuclease cleaves 28S RNA in eukaryotic ribosomes, inhibits protein synthesis, and shows antitumor activity. (176 aa)
AFUA_4G03820Uncharacterized protein. (296 aa)
AFUA_4G03230Extracellular guanyl-specific ribonuclease RntA. (131 aa)
dcl2ATP-dependent helicase dcl2; Dicer-like endonuclease involved in cleaving double-stranded RNA in the RNA interference (RNAi) pathway. Produces 21 to 25 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs leading to sequence-specific suppression of gene expression, called post-transcriptional gene silencing (PTGS). Part of a broad host defense response against viral infection and transposons (By similarity); Belongs to the helicase family. Dicer subfamily. (1388 aa)
AFUA_7G00870RNA exonuclease, putative. (423 aa)
AFUA_7G01330Translin-associated factor TraX, putative. (289 aa)
AFUA_7G01550Mitochondrial exoribonuclease Cyt-4, putative. (1043 aa)
AFUA_8G01900Uncharacterized protein. (278 aa)
AFUA_8G05430Ribosome biogenesis protein Noc4, putative. (569 aa)
AFUA_8G05280RNA interference and gene silencing protein (Qde2), putative. (1047 aa)
USB1U6 snRNA phosphodiesterase; Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA; Belongs to the 2H phosphoesterase superfamily. USB1 family. (306 aa)
AFUA_8G04820Ribonuclease P complex subunit Pop2, putative. (318 aa)
AFUA_8G04640RNA-3'-phosphate cyclase family protein. (403 aa)
AFUA_8G04420mRNA cleavage and polyadenylation specificity factor complex subunit (Pta1), putative. (767 aa)
AFUA_6G021603' exoribonuclease family protein. (411 aa)
AFUA_6G02270Ribonuclease P complex subunit Pop1, putative. (913 aa)
AFUA_6G02530DNA repair protein RAD1, putative. (975 aa)
AFUA_6G04350Uncharacterized protein. (277 aa)
rrp36rRNA biogenesis protein rrp36; Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway (By similarity). (356 aa)
rai1Decapping nuclease rai1; Ribonuclease that specifically degrades pre-mRNAs with a defective 5' end cap and is part of a pre-mRNA capping quality control. Has decapping and pyrophosphohydrolase activities. Has decapping activity toward incomplete 5' end cap mRNAs such as unmethylated 5' end-capped RNA to release GpppN and 5' end monophosphate RNA. Also possesses RNA 5'-pyrophosphohydrolase activity by hydrolyzing the 5' end triphosphate to release pyrophosphates (By similarity). Belongs to the DXO/Dom3Z family. (365 aa)
AFUA_6G05310Nucleolus protein required for cell viability, putative. (241 aa)
AFUA_5G01600PHP domain protein. (486 aa)
AFUA_5G01800DNA repair protein Rad14, putative. (301 aa)
AFUA_5G02030Cleavage and polyadenylation specific factor 5. (334 aa)
AFUA_5G03090Small nucleolar ribonucleoprotein complex subunit (Pwp2), putative. (926 aa)
AFUA_5G031205'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins. (1418 aa)
AFUA_5G03320TFIIH complex helicase Ssl2, putative. (830 aa)
slx1Structure-specific endonuclease subunit slx1; Catalytic subunit of the slx1-slx4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (423 aa)
AFUA_5G0400020S-pre-rRNA D-site endonuclease NOB1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. Belongs to the NOB1 family. (435 aa)
AFUA_5G04010tRNA-splicing endonuclease subunit Sen2; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural [...] (484 aa)
AFUA_5G04070Meiosis-specific topoisomerase Spo11, putative. (388 aa)
AFUA_5G04440Nucleolar RNAse III, putative. (373 aa)
AFUA_3G04110rRNA processing protein Bystin, putative. (497 aa)
AFUA_3G03050RNAse III, putative. (150 aa)
AFUA_3G02450Uncharacterized protein. (1178 aa)
AFUA_7G042703'-5' exonuclease/helicase (Wrn), putative. (419 aa)
AFUA_7G04430Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (220 aa)
AFUA_7G05280Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (822 aa)
AFUA_7G08520Uncharacterized protein. (476 aa)
dbp3ATP-dependent RNA helicase dbp3; ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5.8S rRNAs (By similarity); Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily. (503 aa)
AFUA_2G06220Zinc knuckle domain protein. (632 aa)
AFUA_2G06090Heterogeneous nuclear ribonucleoprotein HRP1. (608 aa)
rex4RNA exonuclease 4; Exoribonuclease involved in ribosome biosynthesis. Involved in the processing of ITS1, the internal transcribed spacer localized between the 18S and 5.8S rRNAs (By similarity); Belongs to the REXO4 family. (310 aa)
AFUA_2G05480DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (121 aa)
pan2n2PAN2-PAN3 deadenylation complex catalytic subunit pan2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein pab1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...] (1155 aa)
AFUA_2G03740Exosome complex endonuclease 1/ribosomal RNA processing protein, putative. (269 aa)
rps2140S ribosomal protein S21; Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Has a physiological role leading to 18S rRNA stability (By similarity). (88 aa)
AFUA_2G03340DUF652 domain protein. (192 aa)
slx4Structure-specific endonuclease subunit slx4; Regulatory subunit of the slx1-slx4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (811 aa)
AFUA_2G02960Protein DOM34 homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (410 aa)
AFUA_2G02400Uncharacterized protein. (240 aa)
AFUA_2G02340Exosome complex exonuclease Rrp40, putative. (274 aa)
grc3Polynucleotide 5'-hydroxyl-kinase grc3; Polynucleotide 5'-kinase involved in rRNA processing. Belongs to the Clp1 family. NOL9/GRC3 subfamily. (841 aa)
AFUA_2G01900RNA polymerase II transcription elongation factor Rtf1p, putative. (607 aa)
AFUA_2G01330Exosome complex subunit Rrp46, putative. (249 aa)
NTH1Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. (432 aa)
AFUA_2G01110Uncharacterized protein. (491 aa)
AFUA_1G07600Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (363 aa)
AFUA_1G07510mRNA cleavage factor complex component Pcf11, putative. (654 aa)
AFUA_1G07090Uncharacterized protein. (1526 aa)
AFUA_1G06380DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (116 aa)
AFUA_1G05410Ribosome biogenesis protein Kri1. (617 aa)
AFUA_1G04950Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (323 aa)
mrd1Multiple RNA-binding domain-containing protein 1; Involved in pre-rRNA processing; Belongs to the RRM MRD1 family. (825 aa)
AFUA_1G04570DNA repair protein, putative. (760 aa)
AFUA_1G04240Small nucleolar ribonucleoprotein complex subunit Utp14, putatrive. (960 aa)
lcl3Probable endonuclease lcl3. (296 aa)
yth1mRNA 3'-end-processing protein yth1; Component of the cleavage factor I (CF I) involved in pre- mRNA 3'-end processing; Belongs to the CPSF4/YTH1 family. (254 aa)
AFUA_1G02680Small nucleolar ribonucleoprotein complex subunit Dip2, putative. (1000 aa)
AFUA_1G02610rRNA processing protein, putative. (325 aa)
AFUA_1G0221060S ribosome biogenesis protein Brx1, putative. (376 aa)
AFUA_1G02200F-box domain protein. (357 aa)
AFUA_1G02060Pachytene checkpoint component Pch2, putative; Belongs to the AAA ATPase family. (455 aa)
AFUA_1G01720Protein kinase and ribonuclease Ire1, putative. (1165 aa)
AFUA_6G14460Haloalkanoic acid dehalogenase, putative. (237 aa)
ubc2Ubiquitin-conjugating enzyme E2 2; Catalyzes the covalent attachment of ubiquitin to other proteins. Plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation. Also involved in postreplication repair of UV-damaged DNA, in N-end rule-dependent protein degradation and in sporulation; Belongs to the ubiquitin-conjugating enzyme family. (151 aa)
AFUA_6G12140Uncharacterized protein. (288 aa)
AFUA_6G11410Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (784 aa)
AFUA_6G10900UV-endonuclease UVE-1. (598 aa)
fip1Pre-mRNA polyadenylation factor fip1; Pre-mRNA polyadenylation factor that directly interacts with poly(A) polymerase; Belongs to the FIP1 family. (338 aa)
AFUA_6G10370RNA lariat debranching enzyme, putative. (785 aa)
AFUA_6G07850Smr domain protein. (569 aa)
AFUA_6G07500DNA excision repair protein Rad2. (1130 aa)
pno1Pre-rRNA-processing protein pno1; Required for small ribosomal subunit (SSU) synthesis. Has a role in the processing of early nucleolar and late cytoplasmic pre-RNA species (By similarity). (252 aa)
AFUA_6G06380Methyltransferase, putative. (245 aa)
AFUA_4G06260Mating-type switch/DNA repair protein Swi10/Rad10, putative. (341 aa)
AFUA_4G07010Hydrolase, TatD family protein, putative. (299 aa)
AFUA_4G07160ATP dependent RNA helicase (Dob1), putative. (1082 aa)
AFUA_4G07290SAP domain-containing protein. (396 aa)
AFUA_4G07500Small nucleolar ribonucleoprotein complex subunit, putative. (656 aa)
AFUA_4G07540Small nucleolar ribonucleoprotein complex subunit, putative. (966 aa)
AFUA_4G12200Uncharacterized protein. (367 aa)
AFUA_4G12210DNA replication helicase Dna2, putative. (1657 aa)
AFUA_4G12250Exosome complex exonuclease exoribonuclease (Rrp44), putative; Belongs to the RNR ribonuclease family. (1034 aa)
AFUA_4G12670DNA repair protein Rad1, putative. (491 aa)
AFUA_4G12680DNA repair protein Rad50. (1312 aa)
ccr4Glucose-repressible alcohol dehydrogenase transcriptional effector; Acts as catalytic component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover. Ccr4 has 3'-5' RNase activity with a strong preference for polyadenylated substrates and also low exonuclease activity towards single-stranded DNA. Discovered because of its role in the control of ADH2 gene expression. It is required for the expression of genes involved in non-fermentative growth (By similarity); Belongs to [...] (696 aa)
ysh1Endoribonuclease ysh1; Component of the cleavage factor I (CF I) involved in pre- mRNA 3'-end processing; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily. (872 aa)
AFUA_1G16600Ribonuclease T2, putative; Belongs to the RNase T2 family. (262 aa)
AFUA_1G16470tRNA processing endoribonuclease Trz1, putative. (1081 aa)
AFUA_1G13910TFIIH complex helicase Rad3, putative. (770 aa)
AFUA_1G13850Uncharacterized protein. (624 aa)
AFUA_1G1273060S ribosomal protein L3. (363 aa)
AFUA_1G11420Cell wall biogenesis protein phosphatase Ssd1, putative. (1378 aa)
AFUA_1G10020Ribonuclease H1, putative. (221 aa)
AFUA_5G06150Uncharacterized protein. (159 aa)
AFUA_5G06830DsRNA-specific ribonuclease III, putative. (142 aa)
AFUA_5G07370CCR4-NOT core complex subunit Caf1, putative. (500 aa)
AFUA_5G07850Decapping enzyme Dcp1, putative. (319 aa)
AFUA_5G09250Transcription factor (Snd1/p100), putative. (980 aa)
AFUA_5G10820Mitochondrial ATP-dependent RNA helicase Suv3, putative. (765 aa)
AFUA_5G11140tRNA-splicing endonuclease subunit Sen34; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structura [...] (310 aa)
AFUA_5G11150Ribonuclease P protein subunit. (232 aa)
AFUA_5G11550tRNA(M5U54)methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (578 aa)
dcl1ATP-dependent helicase dcl1; Dicer-like endonuclease involved in cleaving double-stranded RNA in the RNA interference (RNAi) pathway. Produces 21 to 25 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs leading to sequence-specific suppression of gene expression, called post-transcriptional gene silencing (PTGS). Part of a broad host defense response against viral infection and transposons (By similarity); Belongs to the helicase family. Dicer subfamily. (1537 aa)
AFUA_5G12250Posttranscriptional regulation nuclease (Mkt1), putative. (731 aa)
AFUA_5G12420Decapping enzyme Dcp2, putative. (865 aa)
AFUA_5G12640DNA polymerase gamma. (1135 aa)
AFUA_5G12860Uncharacterized protein. (392 aa)
AFUA_5G13220ERCC4 domain-containing protein. (649 aa)
AFUA_5G13360YjeF_N domain protein. (702 aa)
AFUA_5G13530Exosome complex subunit Csl4, putative. (249 aa)
AFUA_3G05860Exosome complex exonuclease Rrp4, putative. (390 aa)
fen1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (395 aa)
AFUA_3G06160Mating locus protein, putative. (250 aa)
AFUA_3G06180DNA lyase Apn2. (648 aa)
AFUA_3G06380Exosome-associated family protein. (248 aa)
AFUA_3G09050Exonuclease, putative. (658 aa)
pol2DNA polymerase epsilon catalytic subunit A; DNA polymerase II participates in chromosomal DNA replication. (2230 aa)
AFUA_3G09720Cleavage and polyadenylation specificity factor subunit 2. (1013 aa)
AFUA_3G09880Exosome complex exonuclease Rrp6, putative. (764 aa)
AFUA_3G10290Uncharacterized protein. (423 aa)
AFUA_3G11010Eukaryotic translation initiation factor eIF-2C4, putative. (917 aa)
nop9Nucleolar protein 9; RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit (By similarity); Belongs to the NOP9 family. (699 aa)
rny1Ribonuclease T2-like; Rnase which modulates cell survival under stress conditions. Released from the vacuole to the cytoplasm during stress to promote tRNA and rRNA cleavage and to activate separately a downstream pathway that promotes cell death. Involved in cell size, vacuolar morphology and growth at high temperatures and high salt concentration (By similarity). (408 aa)
AFUA_3G11820RNA exonuclease Rex2, putative. (250 aa)
rex3RNA exonuclease 3; 3' to 5' exoribonuclease required for proper 3' end maturation of MRP RNA and of the U5L snRNA; Belongs to the REXO1/REXO3 family. (645 aa)
mus81Crossover junction endonuclease mus81; Interacts with eme1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single- end invasion (SEI) (By similarity); Belongs to the XPF family. (596 aa)
AFUA_3G13260Rad2-like endonuclease, putative. (869 aa)
nop58Nucleolar protein 58; Required for pre-18S rRNA processing. May bind microtubules (By similarity); Belongs to the NOP5/NOP56 family. (591 aa)
AFUA_2G17230NACHT domain protein. (1785 aa)
AFUA_2G16960CAF1 family ribonuclease, putative. (573 aa)
AFUA_2G16830Endonuclease/exonuclease/phosphatase family protein. (300 aa)
esf2Pre-rRNA-processing protein esf2; Involved in the small subunit (SSU) processome assembly and function, and in the 18S rRNA synthesis. Required for the early cleavages at sites A0, A1 and A2 (By similarity); Belongs to the ESF2/ABP1 family. (361 aa)
AFUA_2G16710Uncharacterized protein. (438 aa)
AFUA_2G16600DNA polymerase. (1105 aa)
AFUA_2G16130zf-C2HE domain-containing protein. (280 aa)
AFUA_2G16040rRNA biogenesis protein RRP5, putative. (1822 aa)
AFUA_2G15220DNA repair protein Pso2/Snm1, putative. (850 aa)
AFUA_2G14950Exonuclease, putative. (750 aa)
AFUA_2G13650Endonuclease/exonuclease/phosphatase family protein. (362 aa)
AFUA_2G13570Ribosome biogenesis protein (Bms1), putative. (1182 aa)
AFUA_2G13340Uncharacterized protein. (313 aa)
AFUA_2G131303' exoribonuclease family protein (Rrp42), putative. (390 aa)
AFUA_2G12890Small nucleolar ribonucleoprotein complex subunit, putative. (535 aa)
AFUA_2G12880Pre-rRNA processing protein Tsr1, putative. (803 aa)
AFUA_2G11770SAP30_Sin3_bdg domain-containing protein. (228 aa)
AFUA_2G11380KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. (358 aa)
AFUA_2G11070Tyrosyl-DNA phosphodiesterase, putative. (564 aa)
AFUA_2G09100Polyadenylation factor subunit CstF64, putative. (296 aa)
AFUA_2G08860Exosome complex endonuclease 2/ribosomal RNA processing protein, putative. (292 aa)
AFUA_2G08750Endonuclease. (340 aa)
AFUA_2G08540DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (128 aa)
rat15'-3' exoribonuclease 2; Possesses 5'->3' exoribonuclease activity. Required for the processing of nuclear mRNA and rRNA precursors. May promote termination of transcription by RNA polymerase II (By similarity); Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily. (1058 aa)
Your Current Organism:
Aspergillus fumigatus
NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293
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