STRINGSTRING
nuf2 nuf2 AFUA_5G11390 AFUA_5G11390 AFUA_5G11700 AFUA_5G11700 AFUA_5G13150 AFUA_5G13150 AFUA_5G13220 AFUA_5G13220 AFUA_3G05540 AFUA_3G05540 AFUA_3G06980 AFUA_3G06980 AFUA_3G07280 AFUA_3G07280 AFUA_6G02530 AFUA_6G02530 AFUA_6G02900 AFUA_6G02900 AFUA_6G03770 AFUA_6G03770 AFUA_5G02560 AFUA_5G02560 AFUA_5G04070 AFUA_5G04070 AFUA_7G05890 AFUA_7G05890 AFUA_3G08800 AFUA_3G08800 mus81 mus81 AFUA_2G16850 AFUA_2G16850 AFUA_2G14280 AFUA_2G14280 AFUA_2G13540 AFUA_2G13540 AFUA_1G10410 AFUA_1G10410 AFUA_1G08860 AFUA_1G08860 AFUA_5G07710 AFUA_5G07710 AFUA_2G06320 AFUA_2G06320 AFUA_2G02660 AFUA_2G02660 AFUA_2G02530 AFUA_2G02530 AFUA_1G07590 AFUA_1G07590 AFUA_1G07195 AFUA_1G07195 AFUA_1G02060 AFUA_1G02060 AFUA_1G02000 AFUA_1G02000 AFUA_1G01140 AFUA_1G01140 AFUA_6G13690 AFUA_6G13690 AFUA_6G13080 AFUA_6G13080 AFUA_6G13050 AFUA_6G13050 AFUA_6G12910 AFUA_6G12910 AFUA_6G11030 AFUA_6G11030 AFUA_6G10670 AFUA_6G10670 msh3 msh3 AFUA_4G09640 AFUA_4G09640 AFUA_4G12670 AFUA_4G12670 AFUA_4G12680 AFUA_4G12680 AFUA_1G15120 AFUA_1G15120 AFUA_1G11170 AFUA_1G11170 AFUA_3G13950 AFUA_3G13950 AFUA_3G05575 AFUA_3G05575 AFUA_1G14695 AFUA_1G14695 AFUA_6G10965 AFUA_6G10965 AFUA_4G03980 AFUA_4G03980 AFUA_7G02200 AFUA_7G02200 AFUA_8G05680 AFUA_8G05680 AFUA_8G04140 AFUA_8G04140 AFUA_5G09000 AFUA_5G09000 AFUA_5G09710 AFUA_5G09710
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
nuf2Probable kinetochore protein nuf2; Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. (463 aa)
AFUA_5G11390APSES transcription factor, putative. (427 aa)
AFUA_5G11700DNA mismatch repair protein Mlh1, putative. (709 aa)
AFUA_5G13150SUN domain-containing protein. (732 aa)
AFUA_5G13220ERCC4 domain-containing protein. (649 aa)
AFUA_3G05540Cell cycle protein kinase, putative. (464 aa)
AFUA_3G06980Uncharacterized protein. (304 aa)
AFUA_3G07280Uncharacterized protein. (335 aa)
AFUA_6G02530DNA repair protein RAD1, putative. (975 aa)
AFUA_6G02900Rad21/Rec8 N terminal domain protein. (741 aa)
AFUA_6G03770Oxidoreductase (Msc7), putative; Belongs to the aldehyde dehydrogenase family. (636 aa)
AFUA_5G02560Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (675 aa)
AFUA_5G04070Meiosis-specific topoisomerase Spo11, putative. (388 aa)
AFUA_7G05890Uncharacterized protein. (252 aa)
AFUA_3G08800DUF1767 domain-containing protein. (249 aa)
mus81Crossover junction endonuclease mus81; Interacts with eme1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single- end invasion (SEI) (By similarity); Belongs to the XPF family. (596 aa)
AFUA_2G16850Sister chromatid cohesion and DNA repair protein (BimD), putative. (1492 aa)
AFUA_2G14280Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (769 aa)
AFUA_2G13540CCCH zinc finger and RRM domain protein. (744 aa)
AFUA_1G10410DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (348 aa)
AFUA_1G08860Meiotic recombination protein Ski8/Rec14, putative. (209 aa)
AFUA_5G07710Nuclear migration protein (ApsA), putative. (1639 aa)
AFUA_2G06320Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (529 aa)
AFUA_2G02660DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (629 aa)
AFUA_2G02530Casein kinase I, putative; Belongs to the protein kinase superfamily. (383 aa)
AFUA_1G07590Cupin domain protein. (634 aa)
AFUA_1G07195APH domain-containing protein. (379 aa)
AFUA_1G02060Pachytene checkpoint component Pch2, putative; Belongs to the AAA ATPase family. (455 aa)
AFUA_1G02000DNA mismatch repair protein Msh4, putative. (840 aa)
AFUA_1G01140Uncharacterized protein. (252 aa)
AFUA_6G13690DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1660 aa)
AFUA_6G13080DEAD/DEAH box DNA helicase (Mer3), putative. (1439 aa)
AFUA_6G13050Meiosis specific protein Hop1, putative. (732 aa)
AFUA_6G12910DsDNA-dependent ATPase Rad54, putative. (807 aa)
AFUA_6G11030RNA binding protein MSSP-2, putative. (624 aa)
AFUA_6G10670Uncharacterized protein. (207 aa)
msh3DNA mismatch repair protein msh3; Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with msh2 to form MutS beta, which binds to DNA mismatches thereby initiating DNA repair. Msh3 provides substrate- binding and substrate specificity to the complex. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. Acts mainly to repair insertion-deletion loops (IDLs) from 2 to 13 nucleotides in size, but can also repair base-base and single insertion-deletion mismatches that occur during replication. After mismatch bindi [...] (1123 aa)
AFUA_4G09640Meiotic nuclear division protein 1; Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Belongs to the MND1 family. (189 aa)
AFUA_4G12670DNA repair protein Rad1, putative. (491 aa)
AFUA_4G12680DNA repair protein Rad50. (1312 aa)
AFUA_1G15120DsDNA-dependent ATPase (Rad54b), putative. (969 aa)
AFUA_1G11170DNA mismatch repair protein Msh5, putative. (830 aa)
AFUA_3G13950Mis12-Mtw1 family protein. (589 aa)
AFUA_3G05575TBP interacting domain protein, putative. (186 aa)
AFUA_1G14695DNA repair protein Dds20/Mei5, putative. (286 aa)
AFUA_6G10965Apoptosis-inducing TAF9-like domain 1 family protein, putative. (110 aa)
AFUA_4G03980Chromosome segregation protein (Pcs1), putative. (529 aa)
AFUA_7G02200Meiotic recombination protein (Dmc1), putative; Belongs to the RecA family. (338 aa)
AFUA_8G05680Serine/threonine-protein kinase. (1119 aa)
AFUA_8G04140Uncharacterized protein. (772 aa)
AFUA_5G09000Sister chromatid cohesion protein (Eso1), putative. (672 aa)
AFUA_5G09710Separin, putative. (2120 aa)
Your Current Organism:
Aspergillus fumigatus
NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293
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