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| | ino80 | Chromatin-remodeling ATPase INO80; ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair. (1708 aa) |
| | AFUA_5G06330 | RSC complex subunit (Sth1), putative. (1406 aa) |
| | AFUA_5G06600 | SNF2 family helicase/ATPase, putative. (1827 aa) |
| | AFUA_5G07740 | DSB repair complex subunit Ku70, putative. (691 aa) |
| | AFUA_5G08260 | Uncharacterized protein. (215 aa) |
| | AFUA_5G09000 | Sister chromatid cohesion protein (Eso1), putative. (672 aa) |
| | AFUA_5G10880 | SNF2 family helicase, putative. (1167 aa) |
| | AFUA_5G10890 | DNA helicase; Belongs to the MCM family. (956 aa) |
| | AFUA_5G11170 | Nucleosome remodeling complex ATPase subunit (Snf2h), putative. (986 aa) |
| | AFUA_5G11700 | DNA mismatch repair protein Mlh1, putative. (709 aa) |
| | lig4 | DNA ligase 4; Involved in ds DNA break repair. Has a role in non-homologous integration (NHI) pathways where it is required in the final step of non-homologous end-joining; Belongs to the ATP-dependent DNA ligase family. (979 aa) |
| | AFUA_5G12250 | Posttranscriptional regulation nuclease (Mkt1), putative. (731 aa) |
| | rad5 | DNA repair protein rad5; Probable helicase, member of the UBC2/RAD6 epistasis group. Functions with DNA repair protein RAD18 in error-free postreplication DNA repair. Involved in the maintenance of wild-type rates of instability of simple repetitive sequences such as poly(GT) repeats. Seems to be involved in maintaining a balance which acts in favor of error-prone non-homologous joining during DNA double-strand breaks repairs (By similarity). (1245 aa) |
| | AFUA_5G12640 | DNA polymerase gamma. (1135 aa) |
| | AFUA_5G13330 | Uncharacterized protein. (344 aa) |
| | PIF1 | ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (788 aa) |
| | AFUA_5G15150 | Telomere-associated RecQ helicase, putative. (395 aa) |
| | AFUA_3G05440 | DNA repair protein Rad18, putative. (1082 aa) |
| | chl1 | ATP-dependent DNA helicase chl1; ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (By similarity). May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (By similarity). Has a specific role in chromosome segregation during meiosis II (By similarity). (782 aa) |
| | fen1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (395 aa) |
| | AFUA_3G06160 | Mating locus protein, putative. (250 aa) |
| | AFUA_3G06180 | DNA lyase Apn2. (648 aa) |
| | AFUA_3G06290 | C6 transcription factor, putative. (379 aa) |
| | AFUA_3G06780 | DNA polymerase. (1656 aa) |
| | AFUA_3G08400 | SNF2 family helicase/ATPase, putative. (1133 aa) |
| | AFUA_3G09050 | Exonuclease, putative. (658 aa) |
| | pol2 | DNA polymerase epsilon catalytic subunit A; DNA polymerase II participates in chromosomal DNA replication. (2230 aa) |
| | AFUA_3G09850 | DNA mismatch repair protein Msh2, putative; Component of the post-replicative DNA mismatch repair system (MMR). (940 aa) |
| | AFUA_3G11140 | DNA ligase. (833 aa) |
| | mus81 | Crossover junction endonuclease mus81; Interacts with eme1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single- end invasion (SEI) (By similarity); Belongs to the XPF family. (596 aa) |
| | AFUA_3G13260 | Rad2-like endonuclease, putative. (869 aa) |
| | AFUA_3G14460 | Rad51 family DNA repair protein, putative. (456 aa) |
| | AFUA_3G15395 | Telomere-associated RecQ helicase, putative. (714 aa) |
| | AFUA_2G18100 | Telomere-associated RecQ helicase, putative. (850 aa) |
| | AFUA_2G17230 | NACHT domain protein. (1785 aa) |
| | AFUA_2G16710 | Uncharacterized protein. (438 aa) |
| | ubc2 | Ubiquitin-conjugating enzyme E2 2; Catalyzes the covalent attachment of ubiquitin to other proteins. Plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation. Also involved in postreplication repair of UV-damaged DNA, in N-end rule-dependent protein degradation and in sporulation; Belongs to the ubiquitin-conjugating enzyme family. (151 aa) |
| | AFUA_2G16130 | zf-C2HE domain-containing protein. (280 aa) |
| | AFUA_2G15880 | Mitotic spindle checkpoint protein (Mad2B), putative. (290 aa) |
| | AFUA_2G15220 | DNA repair protein Pso2/Snm1, putative. (850 aa) |
| | AFUA_2G14080 | Structural maintenance of chromosomes protein. (1199 aa) |
| | dbp9 | ATP-dependent RNA helicase dbp9; ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs; Belongs to the DEAD box helicase family. DDX56/DBP9 subfamily. (649 aa) |
| | AFUA_2G13650 | Endonuclease/exonuclease/phosphatase family protein. (362 aa) |
| | AFUA_2G13410 | DNA mismatch repair protein (Pms1), putative. (1044 aa) |
| | AFUA_2G12220 | Replication factor C subunit 1. (1085 aa) |
| | AFUA_2G11070 | Tyrosyl-DNA phosphodiesterase, putative. (564 aa) |
| | AFUA_2G10820 | DEAD/DEAH box helicase, putative. (1206 aa) |
| | AFUA_2G10730 | DNA polymerase. (1462 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (854 aa) |
| | AFUA_2G09120 | SNF2 family helicase, putative. (2115 aa) |
| | AFUA_2G09060 | DNA helicase; Belongs to the MCM family. (1023 aa) |
| | AFUA_2G09010 | DNA ligase. (909 aa) |
| | AFUA_2G08840 | Terminal deoxynucleotidyl transferase, putative. (704 aa) |
| | AFUA_2G08750 | Endonuclease. (340 aa) |
| | AFUA_2G07890 | BRCT domain-containing protein. (307 aa) |
| | AFUA_2G16600 | DNA polymerase. (1105 aa) |
| | AFUA_6G13690 | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1660 aa) |
| | AFUA_6G13290 | SWI/SNF family DNA-dependent ATPase Ris1, putative. (1376 aa) |
| | AFUA_6G13080 | DEAD/DEAH box DNA helicase (Mer3), putative. (1439 aa) |
| | AFUA_6G12910 | DsDNA-dependent ATPase Rad54, putative. (807 aa) |
| | AFUA_6G11410 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (784 aa) |
| | AFUA_6G09220 | SNF2 family helicase/ATPase, putative. (1141 aa) |
| | AFUA_6G08570 | DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1154 aa) |
| | AFUA_6G08110 | DNA (Apurinic or apyrimidinic site) lyase, endon uclease. (561 aa) |
| | AFUA_6G07500 | DNA excision repair protein Rad2. (1130 aa) |
| | AFUA_6G06550 | SNF2 family helicase/ATPase, putative. (1461 aa) |
| | AFUA_4G06490 | DNA mismatch repair protein (Mlh3), putative. (916 aa) |
| | AFUA_4G07010 | Hydrolase, TatD family protein, putative. (299 aa) |
| | AFUA_4G07230 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (538 aa) |
| | AFUA_4G07290 | SAP domain-containing protein. (396 aa) |
| | AFUA_4G07970 | DNA polymerase delta subunit 2, putative. (554 aa) |
| | AFUA_4G08300 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1213 aa) |
| | rvb1 | RuvB-like helicase 1; DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity); Belongs to the RuvB family. (458 aa) |
| | AFUA_4G11140 | DNA polymerase iota, putative. (596 aa) |
| | AFUA_4G11180 | AAA family ATPase, putative. (539 aa) |
| | AFUA_4G11930 | Formamidopyrimidine-DNA glycosylase, putative. (367 aa) |
| | AFUA_4G12210 | DNA replication helicase Dna2, putative. (1657 aa) |
| | AFUA_4G12680 | DNA repair protein Rad50. (1312 aa) |
| | AFUA_4G13440 | Chromatin remodeling complex subunit (Chd3), putative. (1509 aa) |
| | AFUA_4G13460 | SNF2 family helicase/ATPase, putative. (1111 aa) |
| | AFUA_1G15120 | DsDNA-dependent ATPase (Rad54b), putative. (969 aa) |
| | AFUA_1G13910 | TFIIH complex helicase Rad3, putative. (770 aa) |
| | AFUA_1G13850 | Uncharacterized protein. (624 aa) |
| | AFUA_1G12520 | DNA repair protein (Rad57), putative. (647 aa) |
| | AFUA_1G11170 | DNA mismatch repair protein Msh5, putative. (830 aa) |
| | AFUA_1G10480 | DNA polymerase POL4, putative. (702 aa) |
| | AFUA_1G10410 | DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (348 aa) |
| | AFUA_1G10290 | Chromodomain helicase (Chd1), putative. (1523 aa) |
| | AFUA_1G09610 | Uncharacterized protein. (708 aa) |
| | AFUA_6G14670 | C2H2-type domain-containing protein. (146 aa) |
| | AFUA_6G14690 | Telomere-associated RecQ helicase, putative. (352 aa) |
| | AFUA_6G14720 | Telomere-associated RecQ helicase, putative. (1445 aa) |
| | AFUA_1G00630 | SWI/SNF family DNA-dependent ATPase, putative. (1005 aa) |
| | AFUA_1G01600 | Deoxyribodipyrimidine photo-lyase Phr1, putative. (586 aa) |
| | AFUA_1G02000 | DNA mismatch repair protein Msh4, putative. (840 aa) |
| | rvb2 | RuvB-like helicase 2; DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity); Belongs to the RuvB family. (469 aa) |
| | mph1 | ATP-dependent DNA helicase mph1; ATP-dependent DNA helicase involved in DNA damage repair by homologous recombination and in genome maintenance. Capable of unwinding D-loops. Plays a role in limiting crossover recombinants during mitotic DNA double-strand break (DSB) repair. Component of a FANCM-MHF complex which promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork. Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily. (1101 aa) |
| | AFUA_1G03500 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (998 aa) |
| | AFUA_1G04570 | DNA repair protein, putative. (760 aa) |
| | AFUA_1G05260 | DNA-directed DNA polymerase theta, putative. (940 aa) |
| | AFUA_1G05830 | TBP associated factor (Mot1), putative. (1891 aa) |
| | AFUA_1G05860 | Uncharacterized protein. (404 aa) |
| | AFUA_1G06670 | Uncharacterized protein. (405 aa) |
| | AFUA_2G00090 | Telomere-associated RecQ helicase, putative. (460 aa) |
| | AFUA_2G01090 | DNA helicase, putative. (730 aa) |
| | AFUA_2G01110 | Uncharacterized protein. (491 aa) |
| | AFUA_6G06530 | Uncharacterized protein. (249 aa) |
| | AFUA_6G06535 | Uncharacterized protein. (192 aa) |
| | AFUA_6G13340 | Mismatch-specific thymine-DNA glycosylase, putative. (364 aa) |
| | AFUA_1G03035 | HD superfamily hydrolase, putative. (243 aa) |
| | AFUA_7G04783 | Pre-mRNA splicing factor, putative. (889 aa) |
| | AFUA_1G13060 | Regulator of nonsense transcripts, putative. (1079 aa) |
| | AFUA_1G13010 | SNF2 family helicase/ATPase PasG, putative. (867 aa) |
| | AFUA_4G03840 | DNA repair protein Rhp26/Rad26, putative. (1214 aa) |
| | AFUA_7G00090 | Telomere-associated RecQ helicase, putative. (396 aa) |
| | AFUA_7G01270 | DNA-directed polymerase kappa, putative. (614 aa) |
| | AFUA_7G02200 | Meiotic recombination protein (Dmc1), putative; Belongs to the RecA family. (338 aa) |
| | swr1 | Helicase swr1; Catalytic component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling; Belongs to the SNF2/RAD54 helicase family. SWR1 subfamily. (1695 aa) |
| | AFUA_8G02820 | Cell cycle checkpoint protein Rad17, putative. (722 aa) |
| | AFUA_8G07400 | Telomere-associated RecQ helicase, putative. (360 aa) |
| | AFUA_8G05820 | DNA mismatch repair protein, putative. (882 aa) |
| | AFUA_8G04750 | DNA mismatch repair protein Msh1, putative. (1018 aa) |
| | AFUA_6G02530 | DNA repair protein RAD1, putative. (975 aa) |
| | AFUA_6G04350 | Uncharacterized protein. (277 aa) |
| | AFUA_5G01600 | PHP domain protein. (486 aa) |
| | AFUA_5G02430 | ATP dependent DNA ligase domain protein. (912 aa) |
| | AFUA_5G03320 | TFIIH complex helicase Ssl2, putative. (830 aa) |
| | slx1 | Structure-specific endonuclease subunit slx1; Catalytic subunit of the slx1-slx4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (423 aa) |
| | AFUA_5G04070 | Meiosis-specific topoisomerase Spo11, putative. (388 aa) |
| | AFUA_3G02450 | Uncharacterized protein. (1178 aa) |
| | AFUA_3G01310 | Uncharacterized protein. (101 aa) |
| | AFUA_7G03820 | DNA excision repair protein Rad16, putative. (940 aa) |
| | AFUA_7G03830 | DNA repair protein Rad7, protein. (642 aa) |
| | msh3 | DNA mismatch repair protein msh3; Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with msh2 to form MutS beta, which binds to DNA mismatches thereby initiating DNA repair. Msh3 provides substrate- binding and substrate specificity to the complex. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. Acts mainly to repair insertion-deletion loops (IDLs) from 2 to 13 nucleotides in size, but can also repair base-base and single insertion-deletion mismatches that occur during replication. After mismatch bindi [...] (1123 aa) |
| | AFUA_7G04590 | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (1248 aa) |
| | AFUA_7G05280 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (822 aa) |
| | AFUA_7G05320 | DNA N-glycosylase, putative. (349 aa) |
| | AFUA_7G05890 | Uncharacterized protein. (252 aa) |
| | AFUA_7G08480 | SWI/SNF family DNA-dependent ATPase, putative. (707 aa) |
| | AFUA_7G08520 | Uncharacterized protein. (476 aa) |
| | UNG1 | Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (376 aa) |
| | AFUA_2G06130 | Fungal specific transcription factor, putative. (651 aa) |
| | AFUA_2G04960 | RecQ family helicase MusN. (1563 aa) |
| | AFUA_2G03910 | ATP-depentend DNA helicase, putative. (1001 aa) |
| | AFUA_2G03900 | Acetamidase/formamidase family protein. (320 aa) |
| | AFUA_2G03750 | DNA excision repair protein (Rad26L), putative. (1008 aa) |
| | AFUA_2G03460 | C6 transcription factor (Leu3), putative. (920 aa) |
| | slx4 | Structure-specific endonuclease subunit slx4; Regulatory subunit of the slx1-slx4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (811 aa) |
| | AFUA_2G02660 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (629 aa) |
| | ku80 | ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase. Involved in non-homologous end joining (NHEJ) DNA double strand break repair. DNA-binding is sequence-independent but has a high affinity to nicks in double-stranded DNA and to the ends of duplex DNA. Binds to naturally occurring chromosomal ends, and therefore provides chromosomal end protection. Required also for telomere recombination to repair telomeric ends in the absence of telomerase. ku70, of the ku70/ku80 heterodimer, binds to the stem loop of tlc1, the RNA component of telomerase. I [...] (725 aa) |
| | NTH1 | Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. (432 aa) |
