STRINGSTRING
AFUA_3G01790 AFUA_3G01790 AFUA_6G04990 AFUA_6G04990 AFUA_6G02590 AFUA_6G02590 AFUA_6G01870 AFUA_6G01870 AFUA_8G05980 AFUA_8G05980 AFUA_7G00740 AFUA_7G00740 AFUA_7G00730 AFUA_7G00730 AFUA_4G03140 AFUA_4G03140 arp1 arp1 AFUA_6G02242 AFUA_6G02242 AFUA_4G14735 AFUA_4G14735 AFUA_3G02500 AFUA_3G02500 AFUA_3G02460 AFUA_3G02460 AFUA_5G00380 AFUA_5G00380 AFUA_3G01190 AFUA_3G01190 AFUA_3G00730 AFUA_3G00730 AFUA_7G04550 AFUA_7G04550 AFUA_7G04590 AFUA_7G04590 AFUA_2G04940 AFUA_2G04940 cgi121 cgi121 AFUA_2G02780 AFUA_2G02780 ku80 ku80 AFUA_1G06430 AFUA_1G06430 AFUA_6G11130 AFUA_6G11130 AFUA_6G07560 AFUA_6G07560 AFUA_6G07460 AFUA_6G07460 AFUA_4G08830 AFUA_4G08830 AFUA_4G09040 AFUA_4G09040 AFUA_4G09970 AFUA_4G09970 AFUA_4G11330 AFUA_4G11330 AFUA_4G11590 AFUA_4G11590 AFUA_4G13440 AFUA_4G13440 AFUA_1G16350 AFUA_1G16350 AFUA_1G12570 AFUA_1G12570 AFUA_1G10420 AFUA_1G10420 AFUA_5G05750 AFUA_5G05750 AFUA_5G05960 AFUA_5G05960 AFUA_5G06400 AFUA_5G06400 AFUA_5G06600 AFUA_5G06600 AFUA_5G06730 AFUA_5G06730 AFUA_5G07120 AFUA_5G07120 AFUA_5G11470 AFUA_5G11470 tel1 tel1 AFUA_5G13420 AFUA_5G13420 AFUA_5G14570 AFUA_5G14570 AFUA_5G14870 AFUA_5G14870 AFUA_3G07930 AFUA_3G07930 AFUA_3G14150 AFUA_3G14150 bud32 bud32 AFUA_3G14860 AFUA_3G14860 AFUA_3G15020 AFUA_3G15020 AFUA_2G17140 AFUA_2G17140 AFUA_2G16100 AFUA_2G16100 AFUA_2G15490 AFUA_2G15490 AFUA_2G13210 AFUA_2G13210 AFUA_2G12590 AFUA_2G12590
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AFUA_3G01790Isoflavone reductase family protein. (319 aa)
AFUA_6G04990Amino acid transporter, putative. (614 aa)
AFUA_6G02590Protein kinase, putative. (342 aa)
AFUA_6G01870Uncharacterized protein. (399 aa)
AFUA_8G05980Protein kinase, putative. (472 aa)
AFUA_7G00740Protein kinase, putative. (448 aa)
AFUA_7G00730High affinity methionine permease. (557 aa)
AFUA_4G03140Serine protein kinase Sky1, putative. (583 aa)
arp1Scytalone dehydratase arp1; Scytalone dehydratase; part of the gene cluster that mediates the biosynthesis of dihydroxynaphthalene (DHN)-melanin, a bluish-green pigment and a structural component of the conidial wall. The first step of the pathway is the production of the heptaketide naphtopyrone YWA1 by the polyketide synthase alb1 though condensation of acetyl-CoA with malonyl-CoA. The naphtopyrone YWA1 is then converted to the pentaketide 1,3,6,8-tetrahydroxynaphthalene (1,3,6,8-THN) by the heptaketide hydrolyase ayg1 though chain-length shortening. 1,3,6,8-THN is substrate of the h [...] (168 aa)
AFUA_6G02242Serine/threonine-protein kinase, putative. (445 aa)
AFUA_4G14735Serine/threonine protein kinase, putative. (226 aa)
AFUA_3G02500Protein kinase, putative. (430 aa)
AFUA_3G02460Serine protein kinase, putative. (451 aa)
AFUA_5G00380TPR domain protein. (583 aa)
AFUA_3G01190Serine/threonine protein kinase, putative. (202 aa)
AFUA_3G00730GST N-terminal domain-containing protein. (248 aa)
AFUA_7G04550Serine/threonine protein kinase, putative. (389 aa)
AFUA_7G04590Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (1248 aa)
AFUA_2G04940KH domain RNA binding protein. (464 aa)
cgi121EKC/KEOPS complex subunit cgi121; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Cgi121 acts as an allosteric effector that regulates the t(6)A activity of the complex. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transc [...] (189 aa)
AFUA_2G02780KH domain RNA-binding protein. (355 aa)
ku80ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase. Involved in non-homologous end joining (NHEJ) DNA double strand break repair. DNA-binding is sequence-independent but has a high affinity to nicks in double-stranded DNA and to the ends of duplex DNA. Binds to naturally occurring chromosomal ends, and therefore provides chromosomal end protection. Required also for telomere recombination to repair telomeric ends in the absence of telomerase. ku70, of the ku70/ku80 heterodimer, binds to the stem loop of tlc1, the RNA component of telomerase. I [...] (725 aa)
AFUA_1G06430Uncharacterized protein. (138 aa)
AFUA_6G11130Possible replication factor-a protein. (289 aa)
AFUA_6G07560Transcription factor Rap1, putative. (315 aa)
AFUA_6G07460Uncharacterized protein. (1189 aa)
AFUA_4G08830Telomere length regulator protein (Rif1), putative. (1703 aa)
AFUA_4G09040High affinity methionine permease. (537 aa)
AFUA_4G09970Uncharacterized protein. (641 aa)
AFUA_4G11330Aha1 domain family. (379 aa)
AFUA_4G11590Uncharacterized protein. (488 aa)
AFUA_4G13440Chromatin remodeling complex subunit (Chd3), putative. (1509 aa)
AFUA_1G16350Uncharacterized protein. (211 aa)
AFUA_1G12570RNA binding protein Ligatin/Tma64, putative. (652 aa)
AFUA_1G10420Uncharacterized protein. (245 aa)
AFUA_5G05750Protein kinase, putative. (415 aa)
AFUA_5G05960Serine/threonine protein kinase, putative. (544 aa)
AFUA_5G06400Uncharacterized protein. (862 aa)
AFUA_5G06600SNF2 family helicase/ATPase, putative. (1827 aa)
AFUA_5G06730Protein kinase, putative. (418 aa)
AFUA_5G07120RNP domain protein. (352 aa)
AFUA_5G11470MYB DNA binding protein (Tbf1), putative. (846 aa)
tel1Serine/threonine-protein kinase tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability (By similarity). (2796 aa)
AFUA_5G13420Protein kinase domain-containing protein. (582 aa)
AFUA_5G14570T5orf172 domain-containing protein. (509 aa)
AFUA_5G14870Protein kinase, putative. (393 aa)
AFUA_3G07930Glutathione S-transferase, putative. (296 aa)
AFUA_3G14150F-box domain protein. (655 aa)
bud32EKC/KEOPS complex subunit bud32; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. BUD32 has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit KAE1. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is r [...] (277 aa)
AFUA_3G14860Uncharacterized protein. (222 aa)
AFUA_3G15020Methionine permease, putative. (545 aa)
AFUA_2G17140T5orf172 domain-containing protein. (693 aa)
AFUA_2G16100Telomere-binding alpha subunit central domain protein. (635 aa)
AFUA_2G15490TPR domain protein. (562 aa)
AFUA_2G13210DnaJ domain protein. (323 aa)
AFUA_2G12590Lectin C-type domain protein. (597 aa)
Your Current Organism:
Aspergillus fumigatus
NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.