(22 nodes) Microtubule network (Aspergillus fumigatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AFUA_4G01160	Von Willebrand domain protein. (1062 aa)
	AFUA_2G07550	Serine/threonine protein kinase (Ark1), putative; Belongs to the protein kinase superfamily. (396 aa)
	AFUA_2G13450	Dynactin, putative. (1378 aa)
	AFUA_3G14340	Mitotic spindle checkpoint protein (Mad2), putative. (141 aa)
	AFUA_3G11860	Microtubule associated protein EB1, putative. (278 aa)
	AFUA_3G06010	RNA processing protein Emg1, putative. (254 aa)
	AFUA_5G14070	Uncharacterized protein. (124 aa)
	AFUA_1G12380	WD repeat protein. (376 aa)
	stu1	Protein stu1; Microtubule binding protein that promotes the stabilization of dynamic microtubules. Required for mitotic spindle formation (By similarity). (1344 aa)
	AFUA_1G14070	Chromosome segregation protein BIR1, putative. (870 aa)
	AFUA_1G15460	DnaJ domain protein. (885 aa)
	AFUA_4G14740	Serine/threonine protein kinase (Ark1), putative; Belongs to the protein kinase superfamily. (423 aa)
	AFUA_6G12700	DASH complex component Dam1, putative. (204 aa)
	nudF	Nuclear distribution protein nudF; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family. (467 aa)
	AFUA_1G00730	DnaJ domain protein. (547 aa)
	AFUA_1G02550	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
	AFUA_1G07580	Cell polarity protein (Alp11), putative. (274 aa)
	AFUA_2G03150	Kinesin family protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1009 aa)
	AFUA_8G04140	Uncharacterized protein. (772 aa)
	AFUA_8G04660	Noc1p protein, putative. (679 aa)
	AFUA_8G06510	Uncharacterized protein. (172 aa)
	AFUA_7G01400	Kinesin family protein (BimC), putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1190 aa)

Your Current Organism:

Aspergillus fumigatus

NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFUA_1G02550	AFUA_1G07580	Q4WKG5	Q4WJ16	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Cell polarity protein (Alp11), putative.	0.428
AFUA_1G02550	AFUA_2G03150	Q4WKG5	Q4WI43	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Kinesin family protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.680
AFUA_1G02550	AFUA_3G11860	Q4WKG5	Q4WY56	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Microtubule associated protein EB1, putative.	0.869
AFUA_1G02550	AFUA_7G01400	Q4WKG5	Q4WAI2	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Kinesin family protein (BimC), putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.847
AFUA_1G02550	AFUA_8G04660	Q4WKG5	Q4WCF0	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Noc1p protein, putative.	0.667
AFUA_1G02550	AFUA_8G06510	Q4WKG5	Q4WBX0	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Uncharacterized protein.	0.886
AFUA_1G07580	AFUA_1G02550	Q4WJ16	Q4WKG5	Cell polarity protein (Alp11), putative.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.428
AFUA_1G14070	AFUA_2G07550	Q4WS43	Q4X262	Chromosome segregation protein BIR1, putative.	Serine/threonine protein kinase (Ark1), putative; Belongs to the protein kinase superfamily.	0.928
AFUA_1G14070	AFUA_3G14340	Q4WS43	Q4WYU9	Chromosome segregation protein BIR1, putative.	Mitotic spindle checkpoint protein (Mad2), putative.	0.665
AFUA_1G14070	AFUA_4G14740	Q4WS43	Q4WR13	Chromosome segregation protein BIR1, putative.	Serine/threonine protein kinase (Ark1), putative; Belongs to the protein kinase superfamily.	0.928
AFUA_1G14070	AFUA_7G01400	Q4WS43	Q4WAI2	Chromosome segregation protein BIR1, putative.	Kinesin family protein (BimC), putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.402
AFUA_2G03150	AFUA_1G02550	Q4WI43	Q4WKG5	Kinesin family protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.680
AFUA_2G03150	AFUA_2G07550	Q4WI43	Q4X262	Kinesin family protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Serine/threonine protein kinase (Ark1), putative; Belongs to the protein kinase superfamily.	0.496
AFUA_2G03150	AFUA_2G13450	Q4WI43	Q4X0H5	Kinesin family protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Dynactin, putative.	0.450
AFUA_2G03150	AFUA_3G11860	Q4WI43	Q4WY56	Kinesin family protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Microtubule associated protein EB1, putative.	0.777
AFUA_2G03150	AFUA_3G14340	Q4WI43	Q4WYU9	Kinesin family protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Mitotic spindle checkpoint protein (Mad2), putative.	0.882
AFUA_2G03150	AFUA_4G14740	Q4WI43	Q4WR13	Kinesin family protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Serine/threonine protein kinase (Ark1), putative; Belongs to the protein kinase superfamily.	0.496
AFUA_2G03150	AFUA_7G01400	Q4WI43	Q4WAI2	Kinesin family protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin family protein (BimC), putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.946
AFUA_2G03150	AFUA_8G04660	Q4WI43	Q4WCF0	Kinesin family protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Noc1p protein, putative.	0.651
AFUA_2G03150	AFUA_8G06510	Q4WI43	Q4WBX0	Kinesin family protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Uncharacterized protein.	0.516