(33 nodes) Integral component of endoplasmic reticulum membrane network (Aspergillus fumigatus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AFUA_6G04410	DUF1183 domain protein. (325 aa)
	AFUA_4G08200	GPI transamidase component PIG-U, putative. (423 aa)
	AFUA_4G07590	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (465 aa)
	AFUA_4G06950	Integral ER membrane protein Scs2, putative. (328 aa)
	AFUA_4G06290	Longevity-assurance protein (LAC1), putative. (467 aa)
	AFUA_6G06390	Uncharacterized protein. (62 aa)
	AFUA_6G07180	GPI transamidase component PIG-S, putative. (618 aa)
	AFUA_6G09020	GPI transamidase component Gpi16, putative. (600 aa)
	AFUA_6G10460	Ceramide synthase membrane component (LAG1), putative. (440 aa)
	AFUA_6G12760	GPI transamidase component (GAA1), putative. (622 aa)
	AFUA_1G02560	Uncharacterized protein. (253 aa)
	AFUA_1G05000	Uncharacterized protein. (139 aa)
	AFUA_2G00420	RTA1 domain protein. (352 aa)
	AFUA_2G04390	Cytomegalovirus gH-receptor family protein, putative. (1034 aa)
	AFUA_7G04690	Sulfhydryl oxidase. (232 aa)
	AFUA_7G03650	TPR_REGION domain-containing protein. (319 aa)
	AFUA_5G04280	DUF2012 domain-containing protein. (245 aa)
	AFUA_5G01810	PIG-P domain-containing protein. (384 aa)
	las21	GPI ethanolamine phosphate transferase 2; Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI second mannose (By similarity). (767 aa)
	AFUA_6G04890	CaaX prenyl proteinase Rce1. (352 aa)
	AFUA_6G04240	PAP2 domain protein. (214 aa)
	AFUA_6G02150	Signal peptide peptidase, putative. (314 aa)
	AFUA_2G08650	RING finger membrane protein. (1617 aa)
	AFUA_2G10350	ER membrane protein complex subunit 4; Belongs to the EMC4 family. (188 aa)
	AFUA_2G17810	RTA1 domain protein, putative. (360 aa)
	AFUA_3G13270	Phosphatidate cytidylyltransferase, putative. (386 aa)
	AFUA_5G09270	EMC1_C domain-containing protein. (952 aa)
	AFUA_5G06480	Sad1/UNC domain protein. (840 aa)
	AFUA_1G11200	Uncharacterized protein. (192 aa)
	AFUA_1G15130	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family. (398 aa)
	AFUA_4G09950	Uncharacterized protein. (439 aa)
	AFUA_8G05350	ER membrane protein complex subunit 3; The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER). Belongs to the EMC3 family. (268 aa)
	AFUA_1G12550	Membrane-tethered transcription factor (SPT23), putative. (1407 aa)

Your Current Organism:

Aspergillus fumigatus

NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFUA_1G05000	AFUA_1G11200	Q4WJS1	Q4WSY5	Uncharacterized protein.	Uncharacterized protein.	0.960
AFUA_1G05000	AFUA_2G10350	Q4WJS1	Q4X1D5	Uncharacterized protein.	ER membrane protein complex subunit 4; Belongs to the EMC4 family.	0.990
AFUA_1G05000	AFUA_5G04280	Q4WJS1	Q4WEV0	Uncharacterized protein.	DUF2012 domain-containing protein.	0.963
AFUA_1G05000	AFUA_5G09270	Q4WJS1	Q4WUQ2	Uncharacterized protein.	EMC1_C domain-containing protein.	0.985
AFUA_1G05000	AFUA_7G03650	Q4WJS1	Q4WG36	Uncharacterized protein.	TPR_REGION domain-containing protein.	0.997
AFUA_1G05000	AFUA_8G05350	Q4WJS1	Q4WC85	Uncharacterized protein.	ER membrane protein complex subunit 3; The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER). Belongs to the EMC3 family.	0.995
AFUA_1G11200	AFUA_1G05000	Q4WSY5	Q4WJS1	Uncharacterized protein.	Uncharacterized protein.	0.960
AFUA_1G11200	AFUA_2G10350	Q4WSY5	Q4X1D5	Uncharacterized protein.	ER membrane protein complex subunit 4; Belongs to the EMC4 family.	0.913
AFUA_1G11200	AFUA_5G04280	Q4WSY5	Q4WEV0	Uncharacterized protein.	DUF2012 domain-containing protein.	0.540
AFUA_1G11200	AFUA_5G09270	Q4WSY5	Q4WUQ2	Uncharacterized protein.	EMC1_C domain-containing protein.	0.950
AFUA_1G11200	AFUA_7G03650	Q4WSY5	Q4WG36	Uncharacterized protein.	TPR_REGION domain-containing protein.	0.950
AFUA_1G11200	AFUA_8G05350	Q4WSY5	Q4WC85	Uncharacterized protein.	ER membrane protein complex subunit 3; The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER). Belongs to the EMC3 family.	0.950
AFUA_1G15130	AFUA_4G08200	Q4WRT8	Q4WP66	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.	GPI transamidase component PIG-U, putative.	0.995
AFUA_1G15130	AFUA_5G01810	Q4WRT8	Q4WE54	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.	PIG-P domain-containing protein.	0.584
AFUA_1G15130	AFUA_6G07180	Q4WRT8	Q4WN91	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.	GPI transamidase component PIG-S, putative.	0.998
AFUA_1G15130	AFUA_6G09020	Q4WRT8	Q4WMR2	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.	GPI transamidase component Gpi16, putative.	0.998
AFUA_1G15130	AFUA_6G12760	Q4WRT8	Q4WLP8	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.	GPI transamidase component (GAA1), putative.	0.998
AFUA_1G15130	las21	Q4WRT8	Q4WDM5	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.	GPI ethanolamine phosphate transferase 2; Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI second mannose (By similarity).	0.876
AFUA_2G04390	AFUA_5G06480	Q4WHS2	Q4WTX9	Cytomegalovirus gH-receptor family protein, putative.	Sad1/UNC domain protein.	0.628
AFUA_2G10350	AFUA_1G05000	Q4X1D5	Q4WJS1	ER membrane protein complex subunit 4; Belongs to the EMC4 family.	Uncharacterized protein.	0.990