STRINGSTRING
AFUA_8G05350 AFUA_8G05350 AFUA_8G02040 AFUA_8G02040 AFUA_8G01390 AFUA_8G01390 AFUA_7G01030 AFUA_7G01030 AFUA_7G00850 AFUA_7G00850 AFUA_7G00780 AFUA_7G00780 AFUA_7G00710 AFUA_7G00710 AFUA_7G00270 AFUA_7G00270 AFUA_4G02750 AFUA_4G02750 AFUA_4G04590 AFUA_4G04590 encD encD AFUA_6G00660 AFUA_6G00660 AFUA_6G00210 AFUA_6G00210 AFUA_1G12550 AFUA_1G12550 AFUA_1G11900 AFUA_1G11900 AFUA_4G03722 AFUA_4G03722 AFUA_8G02380 AFUA_8G02380 AFUA_1G00100 AFUA_1G00100 AFUA_6G09292 AFUA_6G09292 AFUA_1G13195 AFUA_1G13195 AFUA_5G13392 AFUA_5G13392 AFUA_2G15910 AFUA_2G15910 AFUA_2G11470 AFUA_2G11470 AFUA_2G10205 AFUA_2G10205 AFUA_2G11475 AFUA_2G11475 AFUA_2G08650 AFUA_2G08650 AFUA_2G09355 AFUA_2G09355 AFUA_2G09590 AFUA_2G09590 AFUA_2G10350 AFUA_2G10350 AFUA_2G11370 AFUA_2G11370 AFUA_2G12710 AFUA_2G12710 AFUA_2G12790 AFUA_2G12790 fis1 fis1 AFUA_2G13960 AFUA_2G13960 AFUA_2G14910 AFUA_2G14910 tpc1 tpc1 AFUA_2G15250 AFUA_2G15250 AFUA_2G15260 AFUA_2G15260 atg22-2 atg22-2 AFUA_2G16290 AFUA_2G16290 AFUA_2G16730 AFUA_2G16730 AFUA_2G17360 AFUA_2G17360 AFUA_2G17810 AFUA_2G17810 AFUA_3G13270 AFUA_3G13270 AFUA_3G13010 AFUA_3G13010 AFUA_3G12900 AFUA_3G12900 AFUA_3G11770 AFUA_3G11770 AFUA_3G11530 AFUA_3G11530 AFUA_3G11100 AFUA_3G11100 AFUA_3G10690 AFUA_3G10690 tvp18 tvp18 AFUA_3G08590 AFUA_3G08590 AFUA_3G05660 AFUA_3G05660 AFUA_5G14630 AFUA_5G14630 AFUA_5G11390 AFUA_5G11390 AFUA_5G11280 AFUA_5G11280 AFUA_5G09270 AFUA_5G09270 AFUA_5G08580 AFUA_5G08580 AFUA_5G08100 AFUA_5G08100 AFUA_5G06480 AFUA_5G06480 AFUA_5G06380 AFUA_5G06380 AFUA_5G06300 AFUA_5G06300 AFUA_1G10880 AFUA_1G10880 AFUA_1G11200 AFUA_1G11200 AFUA_1G12250 AFUA_1G12250 AFUA_1G12990 AFUA_1G12990 AFUA_1G14240 AFUA_1G14240 AFUA_1G15130 AFUA_1G15130 PSD1 PSD1 AFUA_4G14260 AFUA_4G14260 AFUA_4G13500 AFUA_4G13500 tvp23 tvp23 AFUA_4G12260 AFUA_4G12260 AFUA_4G10750 AFUA_4G10750 AFUA_4G09950 AFUA_4G09950 AFUA_4G08200 AFUA_4G08200 rcf1 rcf1 mic60 mic60 AFUA_4G07770 AFUA_4G07770 AFUA_4G07750 AFUA_4G07750 AFUA_4G07590 AFUA_4G07590 AFUA_4G06950 AFUA_4G06950 AFUA_4G06870 AFUA_4G06870 AFUA_4G06760 AFUA_4G06760 AFUA_4G06290 AFUA_4G06290 AFUA_4G05990 AFUA_4G05990 AFUA_6G06360 AFUA_6G06360 AFUA_6G06390 AFUA_6G06390 AFUA_6G06570 AFUA_6G06570 AFUA_6G07180 AFUA_6G07180 gem1 gem1 AFUA_6G08080 AFUA_6G08080 AFUA_6G08630 AFUA_6G08630 AFUA_6G09020 AFUA_6G09020 AFUA_6G09880 AFUA_6G09880 AFUA_6G10100 AFUA_6G10100 AFUA_6G10450 AFUA_6G10450 AFUA_6G10460 AFUA_6G10460 AFUA_6G11380 AFUA_6G11380 AFUA_6G12760 AFUA_6G12760 AFUA_6G12860 AFUA_6G12860 AFUA_6G13070 AFUA_6G13070 pyr5 pyr5 AFUA_6G14040 AFUA_6G14040 AFUA_1G00970 AFUA_1G00970 AFUA_1G01380 AFUA_1G01380 AFUA_1G01770 AFUA_1G01770 AFUA_1G02560 AFUA_1G02560 AFUA_1G03440 AFUA_1G03440 AFUA_1G05000 AFUA_1G05000 AFUA_1G05170 AFUA_1G05170 yme2 yme2 AFUA_1G07420 AFUA_1G07420 AFUA_2G00420 AFUA_2G00420 AFUA_2G00570 AFUA_2G00570 AFUA_2G01450 AFUA_2G01450 AFUA_2G01660 AFUA_2G01660 AFUA_2G02680 AFUA_2G02680 AFUA_2G03090 AFUA_2G03090 AFUA_2G03220 AFUA_2G03220 AFUA_2G03520 AFUA_2G03520 AFUA_2G04390 AFUA_2G04390 atg22-1 atg22-1 AFUA_7G05730 AFUA_7G05730 mia40 mia40 AFUA_7G04690 AFUA_7G04690 AFUA_7G04160 AFUA_7G04160 AFUA_7G03650 AFUA_7G03650 AFUA_3G01540 AFUA_3G01540 AFUA_3G02150 AFUA_3G02150 AFUA_3G03200 AFUA_3G03200 AFUA_3G03240 AFUA_3G03240 AFUA_3G03320 AFUA_3G03320 AFUA_5G04310 AFUA_5G04310 AFUA_5G04280 AFUA_5G04280 AFUA_5G03640 AFUA_5G03640 AFUA_5G03630 AFUA_5G03630 AFUA_5G03040 AFUA_5G03040 AFUA_5G01810 AFUA_5G01810 AFUA_5G01000 AFUA_5G01000 las21 las21 AFUA_6G04890 AFUA_6G04890 AFUA_6G04410 AFUA_6G04410 AFUA_6G04240 AFUA_6G04240 AFUA_6G02150 AFUA_6G02150 AFUA_8G06610 AFUA_8G06610
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AFUA_8G05350ER membrane protein complex subunit 3; The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER). Belongs to the EMC3 family. (268 aa)
AFUA_8G02040Glycosyl transferase, putative. (394 aa)
AFUA_8G01390Glycosyl hydrolase, putative. (687 aa)
AFUA_7G01030Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1077 aa)
AFUA_7G00850GNAT family acetyltransferase, putative. (240 aa)
AFUA_7G00780MFS monocarboxylate transporter, putative. (397 aa)
AFUA_7G00710Oxalate/formate antiporter, putative. (430 aa)
AFUA_7G00270FAD binding monooxygenase, putative. (482 aa)
AFUA_4G02750MFS monocarboxylate transporter, putative. (413 aa)
AFUA_4G04590Ubiquinone biosynthesis protein, putative. (687 aa)
encD2-oxoglutarate-Fe(II) type oxidoreductase; 2-oxoglutarate-Fe(II) type oxidoreductase; part of the gene cluster that mediates the biosynthesis of endocrocin, a simple anthraquinone interesting for many biotechnological applications. The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase (PKS) encA. The atrochrysone carboxyl ACP thioesterase encB then breaks the thioester bond and releases the atrochrysone carboxylic acid from encA. The atrochrysone carboxylic acid is then converted to endocrocin anthrone which is further oxidized into endocrocin by en [...] (337 aa)
AFUA_6G00660FAD binding domain protein. (322 aa)
AFUA_6G00210Monocarboxylate transporter, putative. (193 aa)
AFUA_1G12550Membrane-tethered transcription factor (SPT23), putative. (1407 aa)
AFUA_1G11900PQ loop repeat protein. (431 aa)
AFUA_4G03722D-ser_dehydrat domain-containing protein. (394 aa)
AFUA_8G02380FAD-dependent monooxygenase, putative. (475 aa)
AFUA_1G00100MFS monocarboxylate transporter, putative. (206 aa)
AFUA_6G09292Uncharacterized protein. (1091 aa)
AFUA_1G13195MICOS complex subunit MIC10; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (91 aa)
AFUA_5G13392Transmembrane GTPase Fzo1, putative; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (932 aa)
AFUA_2G15910Mannan polymerase II complex ANP1 subunit Anp1, putative. (446 aa)
AFUA_2G11470Uncharacterized protein. (419 aa)
AFUA_2G10205Uncharacterized protein. (694 aa)
AFUA_2G11475BAR domain protein. (305 aa)
AFUA_2G08650RING finger membrane protein. (1617 aa)
AFUA_2G09355Isochorismatase family protein. (185 aa)
AFUA_2G09590UDP-N-acetylglucosamine 1-carboxyvinyltransferase family protein. (109 aa)
AFUA_2G10350ER membrane protein complex subunit 4; Belongs to the EMC4 family. (188 aa)
AFUA_2G11370Autophagy-related protein; Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation. The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation; Belongs to the ATG22 family. (524 aa)
AFUA_2G12710MFS monocarboxylate transporter, putative. (419 aa)
AFUA_2G12790MFS monocarboxylate transporter, putative. (506 aa)
fis1Mitochondrial fission 1 protein; Has a role in mitochondrial fission. Has a role in outer membrane fission but not matrix separation (By similarity). (151 aa)
AFUA_2G13960Tafazzin family protein; Belongs to the taffazin family. (433 aa)
AFUA_2G14910Alpha-1,6-mannosyltransferase subunit, putative. (462 aa)
tpc1Mitochondrial thiamine pyrophosphate carrier 1; Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria; Belongs to the mitochondrial carrier (TC 2.A.29) family. (317 aa)
AFUA_2G15250Uncharacterized protein. (340 aa)
AFUA_2G15260C6 transcription factor (Leu3), putative. (393 aa)
atg22-2Autophagy-related protein 22-2; Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation. The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation (By similarity); Belongs to the ATG22 family. (613 aa)
AFUA_2G16290DnaJ domain protein (Mas5), putative. (420 aa)
AFUA_2G16730Peroxisome biosynthesis protein (PAS10/Peroxin-12), putative. (486 aa)
AFUA_2G17360MFS monocarboxylate transporter (Mct), putative. (441 aa)
AFUA_2G17810RTA1 domain protein, putative. (360 aa)
AFUA_3G13270Phosphatidate cytidylyltransferase, putative. (386 aa)
AFUA_3G13010Zn-dependent hydrolase/oxidoreductase family protein, putative. (407 aa)
AFUA_3G12900MFS transporter, putative. (449 aa)
AFUA_3G11770Autophagy-related protein; Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation. The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation; Belongs to the ATG22 family. (404 aa)
AFUA_3G11530Hsp40 co-chaperone Jid1, putative. (311 aa)
AFUA_3G11100Mitochondrial protein Fmp25, putative. (580 aa)
AFUA_3G10690Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1202 aa)
tvp18Golgi apparatus membrane protein tvp18; Golgi membrane protein involved in vesicular trafficking. Belongs to the TVP18 family. (151 aa)
AFUA_3G08590Uncharacterized protein. (125 aa)
AFUA_3G05660MFS monocarboxylate transporter, putative. (484 aa)
AFUA_5G14630Uncharacterized protein. (119 aa)
AFUA_5G11390APSES transcription factor, putative. (427 aa)
AFUA_5G11280Uncharacterized protein. (329 aa)
AFUA_5G09270EMC1_C domain-containing protein. (952 aa)
AFUA_5G08580Alpha-1,6-mannosyltransferase subunit (Och1), putative. (425 aa)
AFUA_5G08100Uncharacterized protein. (173 aa)
AFUA_5G06480Sad1/UNC domain protein. (840 aa)
AFUA_5G06380Uncharacterized protein. (219 aa)
AFUA_5G06300Peroxisomal membrane protein (Pex3), putative. (528 aa)
AFUA_1G10880Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1432 aa)
AFUA_1G11200Uncharacterized protein. (192 aa)
AFUA_1G12250Mitochondrial hypoxia responsive domain protein. (268 aa)
AFUA_1G12990Uncharacterized protein. (284 aa)
AFUA_1G14240Golgi membrane protein (Coy1), putative. (761 aa)
AFUA_1G15130GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family. (398 aa)
PSD1Phosphatidylserine decarboxylase proenzyme 1, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily. (548 aa)
AFUA_4G14260MFS monocarboxylate transporter, putative. (462 aa)
AFUA_4G13500Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (514 aa)
tvp23Golgi apparatus membrane protein tvp23; Golgi membrane protein involved in vesicular trafficking. Belongs to the TVP23 family. (191 aa)
AFUA_4G12260MFS transporter (Mch2), putative. (518 aa)
AFUA_4G10750Alpha-1,6-mannosyltransferase subunit, putative. (318 aa)
AFUA_4G09950Uncharacterized protein. (439 aa)
AFUA_4G08200GPI transamidase component PIG-U, putative. (423 aa)
rcf1Respiratory supercomplex factor 1, mitochondrial; Cytochrome c oxidase subunit which plays a role in assembly of respiratory supercomplexes. (181 aa)
mic60MICOS complex subunit mic60; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays a role in keeping cristae membranes connected to the inner boundary membrane. Also promotes protein import via the mitochondrial intermembrane space assembly (MIA) pathway (By similarity). (624 aa)
AFUA_4G07770Cation chloride cotransporter, putative. (1228 aa)
AFUA_4G07750Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (125 aa)
AFUA_4G07590CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (465 aa)
AFUA_4G06950Integral ER membrane protein Scs2, putative. (328 aa)
AFUA_4G06870N-glycosyl-transferase. (411 aa)
AFUA_4G06760Ubiquinone biosynthesis protein, putative. (624 aa)
AFUA_4G06290Longevity-assurance protein (LAC1), putative. (467 aa)
AFUA_4G05990Uncharacterized protein. (186 aa)
AFUA_6G06360Mating alpha-pheromone PpgA. (102 aa)
AFUA_6G06390Uncharacterized protein. (62 aa)
AFUA_6G06570Uncharacterized protein. (312 aa)
AFUA_6G07180GPI transamidase component PIG-S, putative. (618 aa)
gem1Mitochondrial Rho GTPase 1; Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution. (632 aa)
AFUA_6G08080Glycosyl hydrolase, putative. (671 aa)
AFUA_6G08630MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (247 aa)
AFUA_6G09020GPI transamidase component Gpi16, putative. (600 aa)
AFUA_6G09880MFS monocarboxylate transporter, putative. (408 aa)
AFUA_6G10100MFS monocarboxylate transporter, putative. (422 aa)
AFUA_6G10450Uncharacterized protein. (248 aa)
AFUA_6G10460Ceramide synthase membrane component (LAG1), putative. (440 aa)
AFUA_6G11380Mitochondrial import receptor subunit (Tom20), putative. (169 aa)
AFUA_6G12760GPI transamidase component (GAA1), putative. (622 aa)
AFUA_6G12860Altered inheritance of mitochondria protein 24, mitochondrial. (412 aa)
AFUA_6G13070UDP-galactose transporter, putative. (423 aa)
pyr5FAD-dependent monooxygenase pyr5; FAD-dependent monooxygenase; part of the gene cluster that mediates the biosynthesis of pyripyropene A, a specific human acyl- coenzyme A:cholesterol acyltransferase 2 inhibitor. The first step of the pathway is the synthesis of nicotinyl-CoA from nicotinic acid by the nicotinic acid-CoA ligase pyr1. Nicotinyl-CoA is then a substrate of polyketide synthase pyr2 to produce 4-hydroxy-6-(3-pyridinyl)-2H-pyran-2-one (HPPO) which is further prenylated by the polyprenyl transferase pyr6 to yield farnesyl-HPPO. The next steps consist of an epoxidation of farn [...] (465 aa)
AFUA_6G14040Glycosyl transferase, putative. (395 aa)
AFUA_1G00970MFS monocarboxylate transporter, putative. (434 aa)
AFUA_1G01380Alpha-1,6-mannosyltransferase subunit (Hoc1), putative. (304 aa)
AFUA_1G01770Short chain oxidoreductase/dehydrogenase, putative; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (284 aa)
AFUA_1G02560Uncharacterized protein. (253 aa)
AFUA_1G03440Peroxisomal carrier protein, putative; Belongs to the mitochondrial carrier (TC 2.A.29) family. (335 aa)
AFUA_1G05000Uncharacterized protein. (139 aa)
AFUA_1G05170MFS monocarboxylate transporter, putative. (436 aa)
yme2Mitochondrial escape protein 2; Plays a role in maintaining the mitochondrial genome and in controlling the mtDNA escape. Involved in the regulation of mtDNA nucleotide structure and number. May have a dispensable role in early maturation of pre-rRNA (By similarity); Belongs to the YME2 family. (871 aa)
AFUA_1G07420SNARE complex subunit (Bet1), putative. (169 aa)
AFUA_2G00420RTA1 domain protein. (352 aa)
AFUA_2G00570GNAT family acetyltransferase, putative. (253 aa)
AFUA_2G01450Alpha-1,6 mannosyltransferase subunit (Mnn9), putative. (397 aa)
AFUA_2G01660Mitochondrial outer membrane translocase receptor (TOM70), putative. (630 aa)
AFUA_2G02680Mitochondrial inner membrane AAA protease Yta12, putative. (885 aa)
AFUA_2G03090Vacuolar ABC heavy metal transporter (Hmt1), putative. (873 aa)
AFUA_2G03220Bax Inhibitor family protein; Belongs to the BI1 family. (337 aa)
AFUA_2G03520MFS monocarboxylate transporter, putative. (520 aa)
AFUA_2G04390Cytomegalovirus gH-receptor family protein, putative. (1034 aa)
atg22-1Autophagy-related protein 22-1; Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation. The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation (By similarity); Belongs to the ATG22 family. (609 aa)
AFUA_7G05730DUF5353 domain-containing protein. (155 aa)
mia40Mitochondrial intermembrane space import and assembly protein 40; Required for the import and folding of small cysteine- containing proteins (small Tim) in the mitochondrial intermembrane space (IMS). Forms a redox cycle with ERV1 that involves a disulfide relay system. Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitochondria. The oxidized form of MIA40 forms a transient intermolecular disulfide bridge with the reduced precursor protein, resulting in oxidation of the precursor protein that now contains an intramolecular disulfide bond [...] (297 aa)
AFUA_7G04690Sulfhydryl oxidase. (232 aa)
AFUA_7G04160Integral peroxisomal membrane protein. (675 aa)
AFUA_7G03650TPR_REGION domain-containing protein. (319 aa)
AFUA_3G01540MFS monocarboxylate transporter, putative. (451 aa)
AFUA_3G02150MFS monocarboxylate transporter, putative. (449 aa)
AFUA_3G03200Cysteine hydrolase family protein. (216 aa)
AFUA_3G03240MFS monocarboxylate transporter, putative. (420 aa)
AFUA_3G03320MFS monocarboxylate transporter, putative. (442 aa)
AFUA_5G04310Peroxisomal membrane protein Pmp47, putative; Belongs to the mitochondrial carrier (TC 2.A.29) family. (324 aa)
AFUA_5G04280DUF2012 domain-containing protein. (245 aa)
AFUA_5G03640Mitochondrial export translocase Oxa1, putative. (436 aa)
AFUA_5G03630Uncharacterized protein. (130 aa)
AFUA_5G03040DnaJ domain protein. (798 aa)
AFUA_5G01810PIG-P domain-containing protein. (384 aa)
AFUA_5G01000Oxidoreductase, 2OG-Fe(II) oxygenase family, putative. (175 aa)
las21GPI ethanolamine phosphate transferase 2; Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI second mannose (By similarity). (767 aa)
AFUA_6G04890CaaX prenyl proteinase Rce1. (352 aa)
AFUA_6G04410DUF1183 domain protein. (325 aa)
AFUA_6G04240PAP2 domain protein. (214 aa)
AFUA_6G02150Signal peptide peptidase, putative. (314 aa)
AFUA_8G06610MFS transporter, putative. (404 aa)
Your Current Organism:
Aspergillus fumigatus
NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293
Server load: low (14%) [HD]