37 items (Aspergillus fumigatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AFUA_6G10540	tRNA splicing endonuclease subunit (Sen54), putative. (460 aa)
	AFUA_2G12010	Pentatricopeptide repeat protein. (699 aa)
	AFUA_3G13260	Rad2-like endonuclease, putative. (869 aa)
	mus81	Crossover junction endonuclease mus81; Interacts with eme1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single- end invasion (SEI) (By similarity); Belongs to the XPF family. (596 aa)
	AFUA_3G12100	Trehalose synthase (Ccg-9), putative. (694 aa)
	AFUA_3G11500	LipA and NB-ARC domain protein. (1458 aa)
	AFUA_3G07460	GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins. (1567 aa)
	AFUA_3G07390	Uncharacterized protein. (139 aa)
	AFUA_5G14780	Heat shock trehalose synthase, putative. (667 aa)
	AFUA_5G13220	ERCC4 domain-containing protein. (649 aa)
	AFUA_5G13210	Alpha-1,2-mannosyltransferase (Alg2), putative. (470 aa)
	AFUA_5G12870	NAD+ kinase, putative. (433 aa)
	AFUA_5G12860	Uncharacterized protein. (392 aa)
	AFUA_5G12850	Cell morphogenesis protein Las1, putative. (376 aa)
	AFUA_5G12840	Hydroxyacylglutathione hydrolase, putative. (246 aa)
	AFUA_5G11150	Ribonuclease P protein subunit. (232 aa)
	AFUA_5G11140	tRNA-splicing endonuclease subunit Sen34; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structura [...] (310 aa)
	AFUA_5G06653	Uncharacterized protein. (174 aa)
	AFUA_4G12200	Uncharacterized protein. (367 aa)
	AFUA_4G11340	Saccharopine dehydrogenase Lys9, putative. (450 aa)
	AFUA_4G09540	Acetyltransferase, GNAT family family. (240 aa)
	AFUA_6G12140	Uncharacterized protein. (288 aa)
	AFUA_1G05430	Sen15 domain-containing protein. (218 aa)
	AFUA_2G01350	NAD+ kinase Utr1, putative. (657 aa)
	AFUA_2G02400	Uncharacterized protein. (240 aa)
	AFUA_3G00290	3-hydroxyacyl-CoA dehydrogenase, putative. (302 aa)
	AFUA_3G04070	BZIP transcription factor HacA. (433 aa)
	AFUA_5G04020	DNA damage repair protein (Rad9), putative. (1338 aa)
	AFUA_5G04010	tRNA-splicing endonuclease subunit Sen2; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural [...] (484 aa)
	AFUA_6G05270	Uncharacterized protein. (195 aa)
	AFUA_6G02270	Ribonuclease P complex subunit Pop1, putative. (913 aa)
	AFUA_8G04820	Ribonuclease P complex subunit Pop2, putative. (318 aa)
	AFUA_8G01900	Uncharacterized protein. (278 aa)
	AFUA_2G04535	Uncharacterized protein. (497 aa)
	AFUA_5G06647	DUF167 domain protein. (133 aa)
	AFUA_3G14160	Uncharacterized protein. (170 aa)
	AFUA_2G09282	Uncharacterized protein. (1097 aa)

Your Current Organism:

Aspergillus fumigatus

NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFUA_1G05430	AFUA_2G02400	Q4WJM8	Q4WIB8	Sen15 domain-containing protein.	Uncharacterized protein.	0.540
AFUA_1G05430	AFUA_2G12010	Q4WJM8	Q4X0X0	Sen15 domain-containing protein.	Pentatricopeptide repeat protein.	0.540
AFUA_1G05430	AFUA_4G12200	Q4WJM8	Q4WQB1	Sen15 domain-containing protein.	Uncharacterized protein.	0.540
AFUA_1G05430	AFUA_5G04010	Q4WJM8	Q4WES2	Sen15 domain-containing protein.	tRNA-splicing endonuclease subunit Sen2; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural [...]	0.631
AFUA_1G05430	AFUA_5G06653	Q4WJM8	Q4WTZ6	Sen15 domain-containing protein.	Uncharacterized protein.	0.540
AFUA_1G05430	AFUA_5G11140	Q4WJM8	Q4WV80	Sen15 domain-containing protein.	tRNA-splicing endonuclease subunit Sen34; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structura [...]	0.761
AFUA_1G05430	AFUA_5G11150	Q4WJM8	Q4WV81	Sen15 domain-containing protein.	Ribonuclease P protein subunit.	0.573
AFUA_1G05430	AFUA_6G02270	Q4WJM8	Q4WCS6	Sen15 domain-containing protein.	Ribonuclease P complex subunit Pop1, putative.	0.554
AFUA_1G05430	AFUA_6G05270	Q4WJM8	Q4WDM6	Sen15 domain-containing protein.	Uncharacterized protein.	0.540
AFUA_1G05430	AFUA_6G10540	Q4WJM8	Q4WMB0	Sen15 domain-containing protein.	tRNA splicing endonuclease subunit (Sen54), putative.	0.813
AFUA_1G05430	AFUA_8G04820	Q4WJM8	Q4WCD4	Sen15 domain-containing protein.	Ribonuclease P complex subunit Pop2, putative.	0.540
AFUA_2G01350	AFUA_5G12870	Q4WIM2	Q4WVP8	NAD+ kinase Utr1, putative.	NAD+ kinase, putative.	0.904
AFUA_2G02400	AFUA_1G05430	Q4WIB8	Q4WJM8	Uncharacterized protein.	Sen15 domain-containing protein.	0.540
AFUA_2G02400	AFUA_2G12010	Q4WIB8	Q4X0X0	Uncharacterized protein.	Pentatricopeptide repeat protein.	0.540
AFUA_2G02400	AFUA_4G12200	Q4WIB8	Q4WQB1	Uncharacterized protein.	Uncharacterized protein.	0.900
AFUA_2G02400	AFUA_5G04010	Q4WIB8	Q4WES2	Uncharacterized protein.	tRNA-splicing endonuclease subunit Sen2; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural [...]	0.540
AFUA_2G02400	AFUA_5G06653	Q4WIB8	Q4WTZ6	Uncharacterized protein.	Uncharacterized protein.	0.900
AFUA_2G02400	AFUA_5G11150	Q4WIB8	Q4WV81	Uncharacterized protein.	Ribonuclease P protein subunit.	0.998
AFUA_2G02400	AFUA_6G02270	Q4WIB8	Q4WCS6	Uncharacterized protein.	Ribonuclease P complex subunit Pop1, putative.	0.999
AFUA_2G02400	AFUA_6G05270	Q4WIB8	Q4WDM6	Uncharacterized protein.	Uncharacterized protein.	0.997