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AFUA_1G10670 AFUA_1G10670 AFUA_2G07520 AFUA_2G07520 AFUA_2G07960 AFUA_2G07960 AFUA_2G08440 AFUA_2G08440 AFUA_2G08990 AFUA_2G08990 AFUA_2G09000 AFUA_2G09000 AFUA_2G09490 AFUA_2G09490 AFUA_2G10010 AFUA_2G10010 AFUA_2G10270 AFUA_2G10270 AFUA_2G10340 AFUA_2G10340 AFUA_2G10460 AFUA_2G10460 AFUA_2G11810 AFUA_2G11810 AFUA_2G13780 AFUA_2G13780 AFUA_2G14180 AFUA_2G14180 AFUA_2G15870 AFUA_2G15870 AFUA_2G16080 AFUA_2G16080 AFUA_2G16090 AFUA_2G16090 AFUA_2G16650 AFUA_2G16650 AFUA_2G16850 AFUA_2G16850 AFUA_2G17050 AFUA_2G17050 AFUA_3G12480 AFUA_3G12480 nop9 nop9 AFUA_3G10360 AFUA_3G10360 AFUA_3G09280 AFUA_3G09280 AFUA_3G08970 AFUA_3G08970 AFUA_3G08780 AFUA_3G08780 AFUA_3G05870 AFUA_3G05870 AFUA_3G05530 AFUA_3G05530 vac8 vac8 tel1 tel1 samB samB AFUA_5G11940 AFUA_5G11940 AFUA_5G11900 AFUA_5G11900 AFUA_5G11720 AFUA_5G11720 AFUA_5G11600 AFUA_5G11600 AFUA_5G11360 AFUA_5G11360 los1 los1 AFUA_5G08670 AFUA_5G08670 AFUA_5G08060 AFUA_5G08060 AFUA_5G07830 AFUA_5G07830 AFUA_5G06560 AFUA_5G06560 AFUA_5G05470 AFUA_5G05470 AFUA_1G08790 AFUA_1G08790 AFUA_1G09620 AFUA_1G09620 AFUA_1G10440 AFUA_1G10440 AFUA_1G10760 AFUA_1G10760 AFUA_1G10970 AFUA_1G10970 stu1 stu1 AFUA_1G13920 AFUA_1G13920 AFUA_1G15720 AFUA_1G15720 AFUA_1G15900 AFUA_1G15900 AFUA_1G16330 AFUA_1G16330 AFUA_7G05700 AFUA_7G05700 AFUA_7G05660 AFUA_7G05660 AFUA_7G05430 AFUA_7G05430 AFUA_7G03760 AFUA_7G03760 AFUA_7G03640 AFUA_7G03640 AFUA_3G04260 AFUA_3G04260 AFUA_5G04340 AFUA_5G04340 AFUA_5G02570 AFUA_5G02570 AFUA_5G02560 AFUA_5G02560 AFUA_5G02170 AFUA_5G02170 AFUA_6G05130 AFUA_6G05130 AFUA_6G04940 AFUA_6G04940 fes1 fes1 AFUA_6G04310 AFUA_6G04310 AFUA_6G04080 AFUA_6G04080 AFUA_6G04010 AFUA_6G04010 AFUA_6G04000 AFUA_6G04000 AFUA_6G03580 AFUA_6G03580 ipi1 ipi1 AFUA_8G04230 AFUA_8G04230 AFUA_8G05370 AFUA_8G05370 AFUA_8G02810 AFUA_8G02810 AFUA_7G01910 AFUA_7G01910 AFUA_4G04310 AFUA_4G04310 AFUA_4G04560 AFUA_4G04560 AFUA_1G05610 AFUA_1G05610 AFUA_1G03590 AFUA_1G03590 cwc22 cwc22 AFUA_1G02510 AFUA_1G02510 utp10 utp10 AFUA_6G12980 AFUA_6G12980 AFUA_6G12890 AFUA_6G12890 AFUA_6G12530 AFUA_6G12530 AFUA_6G11010 AFUA_6G11010 AFUA_6G10440 AFUA_6G10440 AFUA_6G10410 AFUA_6G10410 AFUA_4G04760 AFUA_4G04760 AFUA_6G11190 AFUA_6G11190 AFUA_1G13720 AFUA_1G13720 AFUA_4G10970 AFUA_4G10970 AFUA_4G11290 AFUA_4G11290 AFUA_4G12070 AFUA_4G12070 AFUA_4G12390 AFUA_4G12390 AFUA_6G10380 AFUA_6G10380 AFUA_1G07050 AFUA_1G07050 AFUA_6G10360 AFUA_6G10360 AFUA_6G09990 AFUA_6G09990 AFUA_6G08880 AFUA_6G08880 AFUA_6G08240 AFUA_6G08240 AFUA_6G08170 AFUA_6G08170 AFUA_6G07580 AFUA_6G07580 AFUA_6G06540 AFUA_6G06540 AFUA_4G06150 AFUA_4G06150 AFUA_4G06750 AFUA_4G06750 AFUA_4G07700 AFUA_4G07700 AFUA_4G08480 AFUA_4G08480 AFUA_4G08820 AFUA_4G08820 AFUA_4G10780 AFUA_4G10780 AFUA_2G01980 AFUA_2G01980 AFUA_2G02510 AFUA_2G02510 AFUA_2G02560 AFUA_2G02560 AFUA_2G05020 AFUA_2G05020 AFUA_2G05470 AFUA_2G05470 lia1 lia1 AFUA_2G05610 AFUA_2G05610 AFUA_1G06790 AFUA_1G06790 AFUA_1G06030 AFUA_1G06030 AFUA_1G05910 AFUA_1G05910 AFUA_1G05830 AFUA_1G05830 AFUA_1G05670 AFUA_1G05670 AFUA_7G05970 AFUA_7G05970
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AFUA_1G10670V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (479 aa)
AFUA_2G07520Leucine aminopeptidase 2; Aminopeptidase that preferentially cleaves di- and tripeptides. Also has low epoxide hydrolase activity (in vitro). Can hydrolyze the epoxide leukotriene LTA(4) but it forms preferentially 5,6-dihydroxy-7,9,11,14-eicosatetraenoic acid rather than the cytokine leukotriene B(4) as the product compared to the homologous mammalian enzyme (in vitro). (614 aa)
AFUA_2G07960Translational activator, putative. (2674 aa)
AFUA_2G08440Ubiquitin C-terminal hydrolase, putative; Belongs to the peptidase C19 family. (2531 aa)
AFUA_2G08990Eukaryotic translation initiation factor 5, putative. (421 aa)
AFUA_2G09000Uncharacterized protein. (1181 aa)
AFUA_2G09490Eukaryotic translation initiation factor subunit eIF-4F, putative. (1525 aa)
AFUA_2G10010Nonsense-mediated mRNA decay protein (Nmd5), putative. (1048 aa)
AFUA_2G10270Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2384 aa)
AFUA_2G10340AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (718 aa)
AFUA_2G10460Cytosolic regulator Pianissimo, putative. (1317 aa)
AFUA_2G11810Pre-rRNA processing protein Rrp12, putative. (1270 aa)
AFUA_2G13780Splicing factor 3B subunit 1, putative. (1246 aa)
AFUA_2G14180HEAT repeat protein. (1643 aa)
AFUA_2G15870Importin beta-5 subunit, putative. (1042 aa)
AFUA_2G16080Nuclear cohesin complex subunit (Psc3), putative. (1213 aa)
AFUA_2G16090Importin subunit alpha; Belongs to the importin alpha family. (552 aa)
AFUA_2G16650Uncharacterized protein. (591 aa)
AFUA_2G16850Sister chromatid cohesion and DNA repair protein (BimD), putative. (1492 aa)
AFUA_2G17050Nucleolar complex-associated protein 3; Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm. Belongs to the CBF/MAK21 family. (692 aa)
AFUA_3G12480Conidiophore development protein HymA. (396 aa)
nop9Nucleolar protein 9; RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit (By similarity); Belongs to the NOP9 family. (699 aa)
AFUA_3G10360Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (878 aa)
AFUA_3G09280Eukaryotic translation initiation factor 3 subunit K; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (249 aa)
AFUA_3G08970AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (746 aa)
AFUA_3G08780Nuclear import and export protein Msn5, putative. (1072 aa)
AFUA_3G05870IFRD domain protein. (478 aa)
AFUA_3G05530Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. (1118 aa)
vac8Vacuolar protein 8; Functions in both vacuole inheritance and protein targeting from the cytoplasm to vacuole; Belongs to the beta-catenin family. (578 aa)
tel1Serine/threonine-protein kinase tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability (By similarity). (2796 aa)
samBMYND-type zinc finger protein samB; Involved in determination of the onset of polarized growth and morphogenesis. Plays a role in the regulation of branching in hyphae and spore formation (By similarity); Belongs to the MUB1/samB family. (605 aa)
AFUA_5G11940Tubulin-specific chaperone D, putative. (1201 aa)
AFUA_5G11900Guanine nucleotide exchange factor (Gea2), putative. (1617 aa)
AFUA_5G1172026S proteasome regulatory subunit RPN1; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. (905 aa)
AFUA_5G11600Actin cytoskeleton organization protein (Cro1), putative. (838 aa)
AFUA_5G11360AP-3 adaptor complex subunit beta, putative. (843 aa)
los1Exportin-T; tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Involved in pre-tRNA splicing, probably by affecting the interaction of pre-tRNA with splicing endonuclease (By similarity); Belongs to the exportin family. (1032 aa)
AFUA_5G08670Phosphatidylinositol 3-kinase VPS34. (898 aa)
AFUA_5G08060Importin 13, putative. (1025 aa)
AFUA_5G07830DUF625 domain protein, putative. (885 aa)
AFUA_5G06560RIX1 domain-containing protein. (801 aa)
AFUA_5G05470WAPL domain-containing protein. (737 aa)
AFUA_1G08790Exportin KapK. (1101 aa)
AFUA_1G09620Protein kinase family protein. (777 aa)
AFUA_1G10440PUM-HD domain-containing protein. (698 aa)
AFUA_1G10760CCAAT-box-binding transcription factor. (1112 aa)
AFUA_1G10970Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (955 aa)
stu1Protein stu1; Microtubule binding protein that promotes the stabilization of dynamic microtubules. Required for mitotic spindle formation (By similarity). (1344 aa)
AFUA_1G13920RING zinc finger protein, putative. (1643 aa)
AFUA_1G15720Importin beta-1 subunit. (872 aa)
AFUA_1G15900Importin beta-2 subunit, putative. (937 aa)
AFUA_1G16330Ribosome assembly protein Noc2, putative. (788 aa)
AFUA_7G05700Guanyl-nucleotide exchange factor (Sec7), putative. (2004 aa)
AFUA_7G05660Translation elongation factor eEF-3, putative. (1065 aa)
AFUA_7G05430Nonsense-mediated mRNA decay factor (Upf2), putative. (1162 aa)
AFUA_7G03760Phosphatidylinositol 4-kinase (STT4), putative; Belongs to the PI3/PI4-kinase family. (1804 aa)
AFUA_7G03640AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane. (953 aa)
AFUA_3G04260DNA-binding protein HGH1, putative. (303 aa)
AFUA_5G04340Pumilio-family RNA binding repeat domain protein. (782 aa)
AFUA_5G02570Histone acetylase complex subunit Paf400, putative; Belongs to the PI3/PI4-kinase family. (3896 aa)
AFUA_5G02560Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (675 aa)
AFUA_5G02170Nuclear condensin complex subunit 3, putative. (1120 aa)
AFUA_6G05130snRNA cap binding complex subunit (Gcr3), putative. (661 aa)
AFUA_6G04940Cytokinesis protein SepA/Bni1. (1800 aa)
fes1Hsp70 nucleotide exchange factor fes1; Functions as a nucleotide exchange factor (NEF) for Hsp70 chaperones which accelerates the release of ADP. Required for fully efficient Hsp70-mediated folding of proteins (By similarity). Belongs to the FES1 family. (216 aa)
AFUA_6G04310mRNA binding protein Pumilio 2, putative. (908 aa)
AFUA_6G04080Uncharacterized protein. (2080 aa)
AFUA_6G04010Chromosome segregation protein Cse1, putative. (983 aa)
AFUA_6G04000GTPase activating protein (Tsc2), putative. (1588 aa)
AFUA_6G03580mRNA-nucleus export ATPase (Elf1), putative. (1115 aa)
ipi1Pre-rRNA-processing protein ipi1; Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA. (345 aa)
AFUA_8G04230Uncharacterized protein. (340 aa)
AFUA_8G05370DNA repair/transcription protein, putative. (1063 aa)
AFUA_8G02810ELMO/CED-12 family protein. (696 aa)
AFUA_7G01910DUF1716 domain protein. (585 aa)
AFUA_4G04310AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (939 aa)
AFUA_4G04560GTP binding protein, putative. (565 aa)
AFUA_1G05610Protein phosphotase 2a 65kd regulatory sububit. (616 aa)
AFUA_1G03590Importin 11, putative. (1045 aa)
cwc22Pre-mRNA-splicing factor cwc22; Involved in pre-mRNA splicing. (881 aa)
AFUA_1G02510RNA-binding protein, putative. (1062 aa)
utp10U3 small nucleolar RNA-associated protein 10; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity). (1798 aa)
AFUA_6G12980Spindle pole body component, putative. (911 aa)
AFUA_6G12890Vacuole-associated enzyme activator complex component (Vac14), putative. (927 aa)
AFUA_6G12530Translation initiation factor eif-2b epsilon subunit, putative. (767 aa)
AFUA_6G11010Cell morphogenesis protein (PAG1), putative. (2577 aa)
AFUA_6G10440Uncharacterized protein. (214 aa)
AFUA_6G10410E3 ubiquitin-protein ligase PEP5. (958 aa)
AFUA_4G04760Inositol kinase kinase (UvsB), putative; Belongs to the PI3/PI4-kinase family. (2449 aa)
AFUA_6G11190Protein kinase (VPS15), putative. (1637 aa)
AFUA_1G13720Intracellular protein transport protein (UsoA), putative. (1061 aa)
AFUA_4G10970Drf_GBD domain-containing protein. (859 aa)
AFUA_4G11290Proteasome activator subunit 4, putative. (1965 aa)
AFUA_4G12070Endosomal peripheral membrane protein (Mon2), putative. (1688 aa)
AFUA_4G12390Cell differentiation protein (Rcd1), putative. (394 aa)
AFUA_6G10380Cullin binding protein CanA, putative. (1240 aa)
AFUA_1G07050Armadillo repeat protein. (993 aa)
AFUA_6G10360Protein required for cell viability, putative. (994 aa)
AFUA_6G09990Importin beta-4 subunit, putative. (1095 aa)
AFUA_6G08880Ubiquitin-protein ligase Ufd4, putative. (1817 aa)
AFUA_6G08240HEAT repeat protein (DRIM), putative. (2582 aa)
AFUA_6G08170DNA polymerase V, putative. (981 aa)
AFUA_6G07580Essential cytoplasmic protein Ctr86, putative. (918 aa)
AFUA_6G06540Proteasome component (Ecm29), putative. (1843 aa)
AFUA_4G06150Protein kinase Scy1, putative. (921 aa)
AFUA_4G06750Serine-threonine kinase SepH. (1367 aa)
AFUA_4G07700Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1693 aa)
AFUA_4G0848026S proteasome regulatory subunit RPN2; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. (1140 aa)
AFUA_4G08820Uncharacterized protein. (334 aa)
AFUA_4G10780Ubiquitin-protein ligase (Tom1), putative. (4037 aa)
AFUA_2G01980Nuclear protein (Sgd1), putative. (850 aa)
AFUA_2G02510TORC1 growth control complex subunit Kog1, putative. (1435 aa)
AFUA_2G02560Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (916 aa)
AFUA_2G05020Cellular morphogenesis regulator DopA. (1675 aa)
AFUA_2G05470Sister chromatid cohesion protein. (1772 aa)
lia1Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor. (335 aa)
AFUA_2G05610RNA binding protein Jsn1, putative. (1182 aa)
AFUA_1G06790Importin beta-3 subunit, putative. (1095 aa)
AFUA_1G06030AP-1 complex subunit gamma. (803 aa)
AFUA_1G05910Uncharacterized protein. (469 aa)
AFUA_1G05830TBP associated factor (Mot1), putative. (1891 aa)
AFUA_1G05670Uncharacterized protein. (678 aa)
AFUA_7G05970mRNA transport regulator (Mtr10), putative. (977 aa)
Your Current Organism:
Aspergillus fumigatus
NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293
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