STRINGSTRING
AFUA_3G06420 AFUA_3G06420 AFUA_6G12522 AFUA_6G12522 AFUA_5G01272 AFUA_5G01272 xanC xanC AFUA_5G02690 AFUA_5G02690 AFUA_7G00652 AFUA_7G00652 AFUA_4G04502 AFUA_4G04502 AcuM AcuM AFUA_1G13510 AFUA_1G13510 AFUA_6G11230 AFUA_6G11230 cbf5 cbf5 hhtA hhtA AFUA_6G00120 AFUA_6G00120 AFUA_6G00200 AFUA_6G00200 AFUA_4G01105 AFUA_4G01105 AFUA_4G01510 AFUA_4G01510 AFUA_4G04320 AFUA_4G04320 AFUA_4G03430 AFUA_4G03430 kapC kapC nscR nscR AFUA_7G01310 AFUA_7G01310 AFUA_7G01810 AFUA_7G01810 swr1 swr1 fumR fumR AFUA_8G00750 AFUA_8G00750 AFUA_8G01140 AFUA_8G01140 AFUA_8G01240 AFUA_8G01240 AFUA_8G01990 AFUA_8G01990 AFUA_8G02640 AFUA_8G02640 AFUA_8G02710 AFUA_8G02710 AFUA_8G07360 AFUA_8G07360 AFUA_8G07180 AFUA_8G07180 AFUA_8G07000 AFUA_8G07000 AFUA_8G06460 AFUA_8G06460 AFUA_8G06010 AFUA_8G06010 AFUA_8G05190 AFUA_8G05190 AFUA_8G04540 AFUA_8G04540 AFUA_8G04130 AFUA_8G04130 AFUA_8G04050 AFUA_8G04050 AFUA_8G03970 AFUA_8G03970 AFUA_6G01840 AFUA_6G01840 AFUA_6G02110 AFUA_6G02110 AFUA_6G03110 AFUA_6G03110 fmpR fmpR AFUA_6G04660 AFUA_6G04660 AFUA_5G01550 AFUA_5G01550 AFUA_5G01700 AFUA_5G01700 AFUA_5G01730 AFUA_5G01730 AFUA_5G01900 AFUA_5G01900 htz1 htz1 AFUA_5G02270 AFUA_5G02270 AFUA_5G02520 AFUA_5G02520 AFUA_5G03030 AFUA_5G03030 AFUA_3G04260 AFUA_3G04260 AFUA_3G04230 AFUA_3G04230 AFUA_3G02750 AFUA_3G02750 AFUA_3G02210 AFUA_3G02210 AFUA_3G02160 AFUA_3G02160 AFUA_3G01880 AFUA_3G01880 AFUA_3G01510 AFUA_3G01510 AFUA_3G00690 AFUA_3G00690 AFUA_3G00210 AFUA_3G00210 AFUA_7G04340 AFUA_7G04340 msh3 msh3 AFUA_7G04820 AFUA_7G04820 AFUA_7G04890 AFUA_7G04890 AFUA_7G05080 AFUA_7G05080 AFUA_7G06320 AFUA_7G06320 AFUA_7G08320 AFUA_7G08320 AFUA_2G06320 AFUA_2G06320 acuK acuK cef1 cef1 AFUA_2G05380 AFUA_2G05380 AFUA_2G05310 AFUA_2G05310 AFUA_2G03460 AFUA_2G03460 AFUA_2G03430 AFUA_2G03430 AFUA_2G03050 AFUA_2G03050 AFUA_2G03020 AFUA_2G03020 AFUA_2G02990 AFUA_2G02990 atrR atrR AFUA_2G02660 AFUA_2G02660 ku80 ku80 AFUA_2G02350 AFUA_2G02350 AFUA_2G01190 AFUA_2G01190 AFUA_2G00360 AFUA_2G00360 AFUA_1G07560 AFUA_1G07560 AFUA_1G05740 AFUA_1G05740 AFUA_1G04900 AFUA_1G04900 AFUA_1G04550 AFUA_1G04550 AFUA_1G03920 AFUA_1G03920 amdR amdR AFUA_1G03800 AFUA_1G03800 AFUA_1G03500 AFUA_1G03500 AFUA_1G03410 AFUA_1G03410 AFUA_1G03210 AFUA_1G03210 mph1 mph1 AFUA_1G01590 AFUA_1G01590 AFUA_1G01240 AFUA_1G01240 AFUA_1G00580 AFUA_1G00580 AFUA_6G13690 AFUA_6G13690 AFUA_6G13130 AFUA_6G13130 AFUA_6G12330 AFUA_6G12330 AFUA_6G12160 AFUA_6G12160 AFUA_6G12130 AFUA_6G12130 AFUA_6G11750 AFUA_6G11750 AFUA_6G11640 AFUA_6G11640 AFUA_6G11450 AFUA_6G11450 AFUA_6G10140 AFUA_6G10140 AFUA_6G10010 AFUA_6G10010 AFUA_6G09870 AFUA_6G09870 gliZ gliZ AFUA_6G09335 AFUA_6G09335 AFUA_6G08790 AFUA_6G08790 AFUA_6G08570 AFUA_6G08570 AFUA_6G08550 AFUA_6G08550 AFUA_6G07230 AFUA_6G07230 rtt106 rtt106 AFUA_4G08300 AFUA_4G08300 nosA nosA AFUA_4G09860 AFUA_4G09860 AFUA_4G10110 AFUA_4G10110 prtT prtT AFUA_4G10160 AFUA_4G10160 AFUA_4G10220 AFUA_4G10220 AFUA_4G10820 AFUA_4G10820 AFUA_4G12180 AFUA_4G12180 AFUA_4G12410 AFUA_4G12410 AFUA_4G12560 AFUA_4G12560 AFUA_4G12570 AFUA_4G12570 AFUA_4G13000 AFUA_4G13000 tpcE tpcE tpcD tpcD AFUA_4G14590 AFUA_4G14590 AFUA_1G17640 AFUA_1G17640 AFUA_1G17150 AFUA_1G17150 brlA brlA AFUA_1G15550 AFUA_1G15550 AFUA_1G15470 AFUA_1G15470 AFUA_1G15370 AFUA_1G15370 AFUA_1G14360 AFUA_1G14360 AFUA_1G11620 AFUA_1G11620 AFUA_1G11000 AFUA_1G11000 AFUA_1G10720 AFUA_1G10720 AFUA_1G10580 AFUA_1G10580 AFUA_1G10410 AFUA_1G10410 AFUA_1G10040 AFUA_1G10040 AFUA_5G05600 AFUA_5G05600 ino80 ino80 AFUA_5G06800 AFUA_5G06800 cwc24 cwc24 AFUA_5G07890 AFUA_5G07890 AFUA_5G10040 AFUA_5G10040 AFUA_5G10890 AFUA_5G10890 AFUA_5G12060 AFUA_5G12060 rad5 rad5 atfB atfB PIF1 PIF1 AFUA_5G14290 AFUA_5G14290 AFUA_5G14390 AFUA_5G14390 AFUA_5G14530 AFUA_5G14530 htb1 htb1 hta1 hta1 chl1 chl1 AFUA_3G06050 AFUA_3G06050 AFUA_3G06070 AFUA_3G06070 AFUA_3G06170 AFUA_3G06170 AFUA_3G06740 AFUA_3G06740 AFUA_3G06780 AFUA_3G06780 AFUA_3G06870 AFUA_3G06870 AFUA_3G07070 AFUA_3G07070 AFUA_3G08050 AFUA_3G08050 AFUA_3G08520 AFUA_3G08520 mbf1 mbf1 AFUA_3G09130 AFUA_3G09130 pol2 pol2 AFUA_3G09850 AFUA_3G09850 AFUA_3G10030 AFUA_3G10030 AFUA_3G10160 AFUA_3G10160 nhp6 nhp6 AFUA_3G11960 AFUA_3G11960 pacC pacC AFUA_3G11990 AFUA_3G11990 AFUA_3G12160 AFUA_3G12160 AFUA_3G12180 AFUA_3G12180 AFUA_3G12780 AFUA_3G12780 AFUA_3G12940 AFUA_3G12940 AFUA_3G13600 AFUA_3G13600 AFUA_3G14010 AFUA_3G14010 AFUA_3G14840 AFUA_3G14840 AFUA_2G17860 AFUA_2G17860 AFUA_2G16820 AFUA_2G16820 rad18 rad18 AFUA_2G16600 AFUA_2G16600 AFUA_2G16310 AFUA_2G16310 xlnR xlnR AFUA_2G13860 AFUA_2G13860 creA creA pim1 pim1 AFUA_2G10730 AFUA_2G10730 AFUA_2G10400 AFUA_2G10400 MCM7 MCM7 AFUA_2G09890 AFUA_2G09890 AFUA_2G09060 AFUA_2G09060 AFUA_2G08240 AFUA_2G08240 stuA stuA hhfA hhfA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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AFUA_3G06420DsDNA-binding protein PDCD5, putative. (151 aa)
AFUA_6G12522Stress response transcription factor SrrA/Skn7, putative. (622 aa)
AFUA_5G01272C6 transcription factor, putative. (589 aa)
xanCXanthocillin biosynthesis cluster transcription factor xanC; Transcription regulator that specifically up-regulates the gene cluster that mediates the biosynthesis of the isocyanide xanthocillin and its derivatives; Belongs to the bZIP family. (318 aa)
AFUA_5G02690C6 transcription factor, putative. (807 aa)
AFUA_7G00652C6 and C2H2 transcription factor RegA-like, putative. (874 aa)
AFUA_4G04502Flocculation suppression protein. (583 aa)
AcuMZinc cluster transcription factor acuM; Transcription factor that governs genes involved in reductive and siderophore-mediated iron acquisition, and carbon metabolism. Suppresses the expression of sreA and induces hapX to stimulate expression of genes involved in both reductive iron assimilation and siderophore-mediated iron uptake which is essential for the maximal virulence. Regulates also genes involved in gluconeogenesis. (627 aa)
AFUA_1G13510C6 transcription factor FacB/Cat8. (862 aa)
AFUA_6G11230C6 transcription factor, putative. (625 aa)
cbf5H/ACA ribonucleoprotein complex subunit cbf5; Catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs and play a central role in ribosomal RNA processing. The H/ACA snoRNP complex also mediates pseudouridylation of other types of RNAs. Catalyzes pseudouridylation at position 93 in U2 snRNA. Also catalyzes pseudouridy [...] (487 aa)
hhtAHistone H3; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (136 aa)
AFUA_6G00120C6 transcription factor, putative. (708 aa)
AFUA_6G00200C6 transcription factor, putative. (799 aa)
AFUA_4G01105C6 and C2H2 transcription factor, putative. (384 aa)
AFUA_4G01510C6 transcription factor, putative. (690 aa)
AFUA_4G04320Homeobox transcription factor, putative. (575 aa)
AFUA_4G03430C6 transcription factor, putative. (641 aa)
kapCPutative transcription factor kapC; Putative transcription factor; Belongs to the bZIP family. (280 aa)
nscRC6 finger domain transcription factor nscR; Transcription factor that specifically regulates the neosartoricin biosynthesis gene cluster. (774 aa)
AFUA_7G01310C6 transcription factor, putative. (737 aa)
AFUA_7G01810C6 transcription factor, putative. (864 aa)
swr1Helicase swr1; Catalytic component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling; Belongs to the SNF2/RAD54 helicase family. SWR1 subfamily. (1695 aa)
fumRC6 finger transcription factor fumR; Transcription factor that regulates the expression of the gene clusters that mediate the biosynthesis of pseurotin and fumagillin. (622 aa)
AFUA_8G00750C2H2 transcription factor, putative. (715 aa)
AFUA_8G01140C6 transcription factor, putative. (533 aa)
AFUA_8G01240C6 transcription factor, putative. (563 aa)
AFUA_8G01990C6 transcription factor, putative. (805 aa)
AFUA_8G02640C6 transcription factor, putative. (684 aa)
AFUA_8G02710C6 transcription factor, putative. (887 aa)
AFUA_8G07360C6 transcription factor, putative. (724 aa)
AFUA_8G07180C6 transcription factor, putative. (571 aa)
AFUA_8G07000C6 transcription factor, putative. (755 aa)
AFUA_8G06460C6 transcription factor, putative. (761 aa)
AFUA_8G06010C6 transcription factor, putative. (655 aa)
AFUA_8G05190Myb-like DNA-binding domain protein. (541 aa)
AFUA_8G04540C6 transcription factor, putative. (875 aa)
AFUA_8G04130C6 transcription factor (Ctf1B), putative. (885 aa)
AFUA_8G04050Transcriptional regulator PacG/VIB-1. (583 aa)
AFUA_8G03970C6 finger domain protein, putative. (901 aa)
AFUA_6G01840C6 transcription factor, putative. (663 aa)
AFUA_6G02110MADS box transcription factor Mcm1. (219 aa)
AFUA_6G03110C6 transcription factor, putative. (645 aa)
fmpRC6 finger transcription factor fmpR; Transcription factor that regulates the gene cluster that mediates the biosynthesis of fumipyrrole, a brown pigment that is involved in growth and conidiation. (525 aa)
AFUA_6G04660Centromere protein Cse4, putative. (180 aa)
AFUA_5G01550C6 transcription factor, putative. (689 aa)
AFUA_5G01700Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit. (662 aa)
AFUA_5G01730MYB DNA-binding domain protein. (2031 aa)
AFUA_5G01900Heat shock transcription factor Hsf1, putative. (799 aa)
htz1Histone H2A.Z; Variant histone H2A which can replace H2A in some nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. This variant is enriched at promoters, it may keep them in a repressed state until the appropriate activa [...] (138 aa)
AFUA_5G02270C6 transcription factor, putative. (590 aa)
AFUA_5G02520DNA helicase; Belongs to the MCM family. (718 aa)
AFUA_5G03030C6 transcription factor, putative. (971 aa)
AFUA_3G04260DNA-binding protein HGH1, putative. (303 aa)
AFUA_3G04230Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (667 aa)
AFUA_3G02750C6 transcription factor, putative. (779 aa)
AFUA_3G02210C6 transcription factor, putative. (365 aa)
AFUA_3G02160C6 transcription factor, putative. (708 aa)
AFUA_3G01880Fungal specific transcription factor, putative. (659 aa)
AFUA_3G01510C6 transcription factor, putative. (740 aa)
AFUA_3G00690C6 transcription factor, putative. (720 aa)
AFUA_3G00210C6 finger domain protein, putative. (746 aa)
AFUA_7G04340C6 transcription factor, putative. (850 aa)
msh3DNA mismatch repair protein msh3; Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with msh2 to form MutS beta, which binds to DNA mismatches thereby initiating DNA repair. Msh3 provides substrate- binding and substrate specificity to the complex. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. Acts mainly to repair insertion-deletion loops (IDLs) from 2 to 13 nucleotides in size, but can also repair base-base and single insertion-deletion mismatches that occur during replication. After mismatch bindi [...] (1123 aa)
AFUA_7G04820C6 transcription factor, putative. (553 aa)
AFUA_7G04890C6 transcription factor, putative. (703 aa)
AFUA_7G05080C6 transcription factor, putative. (664 aa)
AFUA_7G06320C6 transcription factor, putative. (588 aa)
AFUA_7G08320Heat shock transcription factor, putative. (275 aa)
AFUA_2G06320Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (529 aa)
acuKTranscription activator of gluconeogenesis acuK; Transcription factor which regulates nonfermentable carbon utilization. Activator of gluconeogenetic genes (By similarity). Belongs to the ERT1/acuK family. (682 aa)
cef1Pre-mRNA-splicing factor cef1; Involved in pre-mRNA splicing and cell cycle control. (792 aa)
AFUA_2G05380C6 transcription factor, putative. (763 aa)
AFUA_2G05310C6 transcription factor, putative. (968 aa)
AFUA_2G03460C6 transcription factor (Leu3), putative. (920 aa)
AFUA_2G03430C6 transcription factor, putative. (696 aa)
AFUA_2G03050Forkhead domain protein. (432 aa)
AFUA_2G03020MYB DNA-binding domain protein. (341 aa)
AFUA_2G02990MYB DNA-binding domain protein. (119 aa)
atrRABC-transporter-regulating transcription factor; Transcription factor that regulates expression of the genes related to ergosterol biosynthesis, including erg3B, erg24A, erg25A, as well as cyp51A that encodes a target protein of azoles. Responsible for the expression of the ABC transporter abcC/cdr1B/abcG1 related to azole resistance. Directly binds both the cyp51A and abcC/cdr1B/abcG1 promoters at a conserved 34 bp region called the atrR response element (ATRE). AtrR also binds to the promoter regions of both the sterol response transcription factor srbA and atrR genes themselves, the [...] (895 aa)
AFUA_2G02660DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (629 aa)
ku80ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase. Involved in non-homologous end joining (NHEJ) DNA double strand break repair. DNA-binding is sequence-independent but has a high affinity to nicks in double-stranded DNA and to the ends of duplex DNA. Binds to naturally occurring chromosomal ends, and therefore provides chromosomal end protection. Required also for telomere recombination to repair telomeric ends in the absence of telomerase. ku70, of the ku70/ku80 heterodimer, binds to the stem loop of tlc1, the RNA component of telomerase. I [...] (725 aa)
AFUA_2G02350MYB DNA-binding domain protein. (937 aa)
AFUA_2G01190Cu-dependent DNA-binding protein, putative. (258 aa)
AFUA_2G00360Homeobox and C2H2 transcription factor, putative. (593 aa)
AFUA_1G07560MYB DNA-binding domain protein. (227 aa)
AFUA_1G05740C6 transcription factor, putative. (1004 aa)
AFUA_1G04900Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (219 aa)
AFUA_1G04550HMG box protein, putative. (309 aa)
AFUA_1G03920DNA helicase; Belongs to the MCM family. (892 aa)
amdRAcetamidase regulatory protein; Positively regulates the expression of genes involved in the catabolism of certain amides, omega amino acids, and lactams. (772 aa)
AFUA_1G03800C6 transcription factor, putative. (822 aa)
AFUA_1G03500DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (998 aa)
AFUA_1G03410DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (500 aa)
AFUA_1G03210MYB family conidiophore development protein FlbD, putative. (314 aa)
mph1ATP-dependent DNA helicase mph1; ATP-dependent DNA helicase involved in DNA damage repair by homologous recombination and in genome maintenance. Capable of unwinding D-loops. Plays a role in limiting crossover recombinants during mitotic DNA double-strand break (DSB) repair. Component of a FANCM-MHF complex which promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork. Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily. (1101 aa)
AFUA_1G01590C6 transcription factor, putative. (838 aa)
AFUA_1G01240C6 transcription factor, putative. (832 aa)
AFUA_1G00580Transcriptional regulator PacG/VIB-1. (529 aa)
AFUA_6G13690DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1660 aa)
AFUA_6G13130Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (290 aa)
AFUA_6G12330DNA damage-binding protein cmr1; DNA-binding protein that binds to both single- and double- stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes. (527 aa)
AFUA_6G12160C6 transcription factor, putative. (697 aa)
AFUA_6G12130C6 transcription factor, putative. (704 aa)
AFUA_6G11750C6 transcription factor, putative. (551 aa)
AFUA_6G11640Fungal specific transcription factor, putative. (494 aa)
AFUA_6G11450C6 transcription factor, putative. (686 aa)
AFUA_6G10140C6 transcription factor, putative. (715 aa)
AFUA_6G10010C6 transcription factor, putative. (649 aa)
AFUA_6G09870C6 transcription factor, putative. (728 aa)
gliZC6 finger domain transcription factor gliZ; Transcription factor that regulates gliotoxin production and contributes to virulence. (489 aa)
AFUA_6G09335SRF-type transcription factor family protein. (130 aa)
AFUA_6G08790C6 transcription factor (PrnA), putative. (803 aa)
AFUA_6G08570DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1154 aa)
AFUA_6G08550C6 transcription factor, putative. (797 aa)
AFUA_6G07230C6 transcription factor, putative. (681 aa)
rtt106Histone chaperone rtt106; Histones H3 and H4 chaperone involved in the nucleosome formation and heterochromatin silencing. Required for the deposition of H3K56ac-carrying H3-H4 complex onto newly-replicated DNA. Plays a role in the transcriptional regulation of the cell-cycle dependent histone genes by creating a repressive structure at the core histone gene promoter (By similarity). (459 aa)
AFUA_4G08300DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1213 aa)
nosAC6 finger domain transcription factor nosA; Transcription factor that mediates stress and developmental response. (685 aa)
AFUA_4G09860C6 transcription factor, putative. (688 aa)
AFUA_4G10110Homeobox transcription factor, putative. (274 aa)
prtTTranscriptional activator of proteases prtT; Transcription factor required for protein utilization and degradation. Regulates transcription of major secreted proteases including a serine alkaline protease (alk1), a metalloprotease (mep), an aspergillopepsin (pep1), a sedolisin (sed2) and two dipeptidyl- peptidases (dppIV and dppV). However, it is not a virulence determinant in leukopenic mice; Belongs to the prtT family. (696 aa)
AFUA_4G10160C6 transcription factor (AmyR), putative. (622 aa)
AFUA_4G10220Homeobox transcription factor (RfeB), putative. (603 aa)
AFUA_4G10820HMG box transcriptional regulator, putative. (688 aa)
AFUA_4G12180C6 transcription factor Prf, putative. (851 aa)
AFUA_4G12410HMG box protein, putative. (507 aa)
AFUA_4G12560C6 transcription factor, putative. (843 aa)
AFUA_4G12570C6 transcription factor, putative. (645 aa)
AFUA_4G13000Lysine-specific histone demethylase Aof2, putative. (1081 aa)
tpcETrypacidin cluster transcription factor; Transcription factor that regulates the expression of the gene clusters that mediate the biosynthesis of trypacidin, a metabolite with antiprotozoal activity and a possible role in the infection process. Trypacidin is toxic for human pulmonary and bronchial epithelial cells by initiating the intracellular formation of nitric oxide (NO) and hydrogen peroxide (H(2)O(2)), thus triggering host necrotic cell death. (396 aa)
tpcDTrypacidin cluster transcriptional coactivator tpcD; Transcriptional coactivator; part of the gene cluster that mediates the biosynthesis of trypacidin, a mycotoxin with antiprotozoal activity and that plays a role in the infection process. With tpcE, coregulates the production of trypacidin. (437 aa)
AFUA_4G14590C6 transcription factor, putative. (654 aa)
AFUA_1G17640C6 transcription factor RegA. (866 aa)
AFUA_1G17150C6 transcription factor, putative. (633 aa)
brlAC2H2 type master regulator of conidiophore development brlA; BrlA, abaA and wetA are pivotal regulators of conidiophore development and conidium maturation. They act individually and together to regulate their own expression and that of numerous other sporulation-specific genes (By similarity). Binds promoters of target genes at brlA response elements (BREs) containing the conserved sequence 5'-(C/A)(A/G)AGGG(G/A)-3' (By similarity). Positively regulates expression of the gliotoxin biosynthetic gene cluster in actively growing vegetative cells, and likely bridges morphological and chem [...] (426 aa)
AFUA_1G15550Homeobox and C2H2 transcription factor, putative. (870 aa)
AFUA_1G15470C6 transcription factor (UaY), putative. (1088 aa)
AFUA_1G15370C6 transcription factor, putative. (1045 aa)
AFUA_1G14360C6 transcription factor, putative. (738 aa)
AFUA_1G11620C6 transcription factor QutA, putative. (905 aa)
AFUA_1G11000C6 transcription factor, putative. (795 aa)
AFUA_1G10720Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (789 aa)
AFUA_1G10580Homeobox transcription factor, putative. (697 aa)
AFUA_1G10410DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (348 aa)
AFUA_1G10040HMG box protein, putative. (399 aa)
AFUA_5G05600Forkhead transcription factor (Sep1), putative. (724 aa)
ino80Chromatin-remodeling ATPase INO80; ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair. (1708 aa)
AFUA_5G06800C6 transcription factor, putative. (606 aa)
cwc24Pre-mRNA-splicing factor cwc24; Involved in pre-mRNA splicing. (339 aa)
AFUA_5G07890SsDNA binding protein, putative. (149 aa)
AFUA_5G10040C6 transcription factor, putative. (683 aa)
AFUA_5G10890DNA helicase; Belongs to the MCM family. (956 aa)
AFUA_5G12060C2H2 transcription factor, putative. (1062 aa)
rad5DNA repair protein rad5; Probable helicase, member of the UBC2/RAD6 epistasis group. Functions with DNA repair protein RAD18 in error-free postreplication DNA repair. Involved in the maintenance of wild-type rates of instability of simple repetitive sequences such as poly(GT) repeats. Seems to be involved in maintaining a balance which acts in favor of error-prone non-homologous joining during DNA double-strand breaks repairs (By similarity). (1245 aa)
atfBBasic leucine zipper (bZIP) transcription factor atfB; Transcription factor that acts as a key player in the regulatory circuit that integrates secondary metabolism and cellular response to oxidative stress (By similarity). Regulates the genes involved in development, as well as osmotic, oxidative, and cell wall stresses. Participates in the caspofungin paradoxical effect (CPE), where fungi grow beyond the minimum inhibitory concentration of caspofungin. Plays a role in virulence ; Belongs to the bZIP family. ATF subfamily. (328 aa)
PIF1ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (788 aa)
AFUA_5G14290C6 transcription factor, putative. (787 aa)
AFUA_5G14390C6 transcription factor, putative. (606 aa)
AFUA_5G14530C6 transcription factor, putative. (601 aa)
htb1Histone H2B; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (140 aa)
hta1Histone H2A; Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (133 aa)
chl1ATP-dependent DNA helicase chl1; ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (By similarity). May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (By similarity). Has a specific role in chromosome segregation during meiosis II (By similarity). (782 aa)
AFUA_3G06050Fungal specific transcription factor, putative. (742 aa)
AFUA_3G06070Histone H1. (206 aa)
AFUA_3G06170Mating type protein MAT1-2-1. (322 aa)
AFUA_3G06740C6 transcription factor (Gal4), putative. (672 aa)
AFUA_3G06780DNA polymerase. (1656 aa)
AFUA_3G06870MYB DNA-binding domain protein. (662 aa)
AFUA_3G07070MYB DNA-binding domain protein. (911 aa)
AFUA_3G08050C6 transcription factor (OTam), putative. (738 aa)
AFUA_3G08520SRF-type transcription factor RlmA. (600 aa)
mbf1Multiprotein-bridging factor 1; Transcriptional coactivator that stimulates transcriptional activity by bridging regulatory proteins and TBP, thereby recruiting TBP to promoters occupied by DNA-binding regulators. (154 aa)
AFUA_3G09130C6 transcription factor, putative. (777 aa)
pol2DNA polymerase epsilon catalytic subunit A; DNA polymerase II participates in chromosomal DNA replication. (2230 aa)
AFUA_3G09850DNA mismatch repair protein Msh2, putative; Component of the post-replicative DNA mismatch repair system (MMR). (940 aa)
AFUA_3G10030Forkhead domain protein. (1160 aa)
AFUA_3G10160C6 transcription factor, putative. (874 aa)
nhp6Non-histone chromosomal protein 6; DNA-binding protein that induces severe bending of DNA. Required for DNA-binding by the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. Also augments the fidelity of transcription by RNA polymerase III independently of any role in the FACT complex (By similarity). (104 aa)
AFUA_3G11960Forkhead transcription factor Fkh1/2, putative. (722 aa)
pacCpH-response transcription factor pacC/RIM101; Transcription factor that mediates regulation of both acid- and alkaline-expressed genes in response to ambient pH. At alkaline ambient pH, activates transcription of alkaline-expressed genes (including pacC itself) and represses transcription of acid- expressed genes (By similarity). (676 aa)
AFUA_3G11990C6 transcription factor (Mut3), putative. (1062 aa)
AFUA_3G12160Homeobox transcription factor, putative. (590 aa)
AFUA_3G12180C6 transcription factor, putative. (692 aa)
AFUA_3G12780C6 transcription factor, putative. (670 aa)
AFUA_3G12940C6 transcription factor, putative. (754 aa)
AFUA_3G13600C6 transcription factor, putative. (629 aa)
AFUA_3G14010DNA helicase; Belongs to the MCM family. (896 aa)
AFUA_3G14840C6 transcription factor, putative. (646 aa)
AFUA_2G17860C6 transcription factor, putative. (644 aa)
AFUA_2G16820Curved DNA-binding protein (42 kDa protein). (426 aa)
rad18Postreplication repair E3 ubiquitin-protein ligase rad18; E3 RING-finger protein, member of the UBC2/RAD6 epistasis group. Associates to the E2 ubiquitin conjugating enzyme UBC2/RAD6 to form the UBC2-RAD18 ubiquitin ligase complex involved in postreplicative repair (PRR) of damaged DNA. (418 aa)
AFUA_2G16600DNA polymerase. (1105 aa)
AFUA_2G16310Fungal specific transcription factor, putative. (755 aa)
xlnRXylanolytic transcriptional activator xlnR; Transcriptional activator of the xylanolytic system. Involved in the regulation of extracellular cellulolytic and xylanolytic genes and in the regulation of the intracellular activities of D-xylose catabolic genes in the pentose catabolic pathway (PCP) in response to the presence of D-xylose (By similarity); Belongs to the xlnR/xlr1 family. (954 aa)
AFUA_2G13860Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (142 aa)
creAProbable DNA-binding protein creA; Transcription regulator component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB. Represses the transcription of the alcR, alcA and aldA genes by binding to a GC- rich region in their promoter. Plays also a role in response to carbon starvation and the control of extracellular proteases activity (By similarity); Belongs to the creA/MIG C2H2-type zinc-finger protein family. (424 aa)
pim1Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family. (1108 aa)
AFUA_2G10730DNA polymerase. (1462 aa)
AFUA_2G10400C6 transcription factor, putative. (611 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (854 aa)
AFUA_2G09890NDT80 / PhoG like DNA-binding family protein. (605 aa)
AFUA_2G09060DNA helicase; Belongs to the MCM family. (1023 aa)
AFUA_2G08240C6 transcription factor, putative. (726 aa)
stuACell pattern formation-associated protein stuA; Transcription factor that regulates asexual reproduction. Binds the StuA-response elements (StRE) with the consensus sequence 5'-(A/T)CGCG(T/A)N(A/C)-3' at the promoters of target genes (By similarity). Controls the expression of 6 secondary metabolite biosynthetic clusters including 2 involved in the synthesis of alkaloids (fumigaclavine and fumitremorgen), 2 clusters of the ETP class (gliotoxin and an unknown ETP-like toxin), a cluster predicted to produce pseurotin A, and the product of the last cluster is unknown. Controls the product [...] (635 aa)
hhfAHistone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
Your Current Organism:
Aspergillus fumigatus
NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293
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