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rglA rglA gpi14 gpi14 pgaB pgaB chsD chsD rglB rglB AFUA_1G17220 AFUA_1G17220 agdC agdC btgC btgC pelA pelA rhgB rhgB pgxC pgxC exgB exgB ecm14 ecm14 chs7 chs7 crf1 crf1 phoA phoA chsC chsC exgD exgD chsG chsG pgaA pgaA pgxB pgxB xghA xghA pmeA pmeA plyE plyE sun1 sun1 eglC eglC pgaX pgaX mcd4 mcd4 plyC plyC rodA rodA plyF plyF exgA exgA xgeA xgeA galA galA plyA plyA pelB pelB AFUA_2G01870 AFUA_2G01870 plyD plyD
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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rglAProbable rhamnogalacturonate lyase A; Pectinolytic enzymes consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Degrades the rhamnogalacturonan I (RG-I) backbone of pectin (By similarity). (528 aa)
gpi14GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly. Required for cell wall integrity (By similarity). (425 aa)
pgaBProbable endopolygalacturonase B; Involved in maceration and soft-rotting of plant tissue. Hydrolyzes the 1,4-alpha glycosidic bonds of de-esterified pectate in the smooth region of the plant cell wall (By similarity). (364 aa)
chsDChitin synthase D; Plays a major role in cell wall biogenesis. (745 aa)
rglBProbable rhamnogalacturonate lyase B; Pectinolytic enzymes consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Degrades the rhamnogalacturonan I (RG-I) backbone of pectin (By similarity). (658 aa)
AFUA_1G17220Probable endopolygalacturonase AFUA_1G17220; Involved in maceration and soft-rotting of plant tissue. Hydrolyzes the 1,4-alpha glycosidic bonds of de-esterified pectate in the smooth region of the plant cell wall (By similarity). (378 aa)
agdCProbable alpha/beta-glucosidase agdC; Glucosidase involved in the degradation of cellulosic biomass. Has both alpha- and beta-glucosidase activity (By similarity). Belongs to the glycosyl hydrolase 31 family. (881 aa)
btgCProbable glucan endo-1,3-beta-glucosidase btgC; Glucanases play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation. This enzyme may be involved in beta-glucan degradation. Active on laminarin and lichenan (By similarity). (688 aa)
pelAProbable pectin lyase A; Pectinolytic enzymes consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins (By similarity). (380 aa)
rhgBProbable rhamnogalacturonase B; Pectinolytic enzymes consist of four classes of enzymes: pectine lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Hydrolyzes alpha-D-galacturonopyranosyl-(1,2)- alpha-L-rhamnopyranosyl linkages in the backbone of the hairy regions of pectins (By similarity). (521 aa)
pgxCProbable exopolygalacturonase C; Specific in hydrolyzing the terminal glycosidic bond of polygalacturonic acid and oligogalacturonates. (440 aa)
exgBProbable glucan endo-1,6-beta-glucosidase B; Beta-glucanases participate in the metabolism of beta-glucan, the main structural component of the cell wall. Acts on lutean, pustulan and 1,6-oligo-beta-D-glucosides (By similarity). (396 aa)
ecm14Putative metallocarboxypeptidase ecm14; Probable carboxypeptidase that may be involved in cell wall organization and biogenesis. (586 aa)
chs7Chitin synthase export chaperone; Chaperone required for the export of the chitin synthase chs3 from the endoplasmic reticulum. (331 aa)
crf1Probable glycosidase crf1. (395 aa)
phoAAcid phosphatase; Has both phosphomonoesterase and phosphodiesterase activity. Cleaves a broad range of phosphate esters. (447 aa)
chsCChitin synthase C; Plays a major role in cell wall biogenesis. (893 aa)
exgDProbable glucan 1,3-beta-glucosidase D; Glucosidase involved in the degradation of cellulosic biomass. Active on lichenan (By similarity). (833 aa)
chsGChitin synthase G; Plays a major role in cell wall biogenesis and required for normal hyphal growth and development. (911 aa)
pgaAProbable endopolygalacturonase A; Involved in maceration and soft-rotting of plant tissue. Hydrolyzes the 1,4-alpha glycosidic bonds of de-esterified pectate in the smooth region of the plant cell wall (By similarity). (368 aa)
pgxBProbable exopolygalacturonase B; Specific in hydrolyzing the terminal glycosidic bond of polygalacturonic acid and oligogalacturonates. (453 aa)
xghAProbable endo-xylogalacturonan hydrolase A; Pectinolytic enzyme involved in the degradation of xylogalacturonan (xga), a galacturonan backbone heavily substituted with xylose, and which is one important component of the hairy regions of pectin. Activity requires a galacturonic acid backbone substituted with xylose (By similarity); Belongs to the glycosyl hydrolase 28 family. (406 aa)
pmeAProbable pectinesterase A; Involved in maceration and soft-rotting of plant tissue. Belongs to the pectinesterase family. (324 aa)
plyEProbable pectate lyase E; Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins. Favors pectate, the anion, over pectin, the methyl ester (By similarity); Belongs to the polysaccharide lyase 3 family. (254 aa)
sun1Secreted beta-glucosidase sun1; Cell surface beta-glucosidase involved in cell wall biosynthesis and septation, and thus required for normal growth and correct hyphal morphogenesis. Has hydrolytic activity on linear (1->3)- beta-D-glucans such as laminaribiose and other laminarioligosaccharides. Has also a minor transferase activity. Belongs to the SUN family. (414 aa)
eglCProbable glucan endo-1,3-beta-glucosidase eglC; Glucanases play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation. This enzyme may be involved in beta-glucan degradation and also function biosynthetically as a transglycosylase (By similarity). Belongs to the glycosyl hydrolase 17 family. (446 aa)
pgaXProbable exopolygalacturonase X; Specific in hydrolyzing the terminal glycosidic bond of polygalacturonic acid and oligogalacturonates. (432 aa)
mcd4GPI ethanolamine phosphate transferase 1; Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor (By similarity). (1032 aa)
plyCProbable pectate lyase C; Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins. Favors pectate, the anion, over pectin, the methyl ester (By similarity); Belongs to the polysaccharide lyase 1 family. (420 aa)
rodAHydrophobin; Cell wall protein regularly arranged in interwoven fascicules of clustered proteinaceous microfibrils, or rodlets, to form the outer spore coat protein. It is involved in resistance to environmental stress and may well be associated with conidial hydrophobicity. It is important in the morphogenesis of the dispersible conidia. (159 aa)
plyFProbable pectate lyase F; Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins. Favors pectate, the anion, over pectin, the methyl ester (By similarity); Belongs to the polysaccharide lyase 3 family. (234 aa)
exgAProbable glucan 1,3-beta-glucosidase A; Beta-glucanases participate in the metabolism of beta-glucan, the main structural component of the cell wall. It could also function biosynthetically as a transglycosylase (By similarity). (416 aa)
xgeAProbable xyloglucan-specific endo-beta-1,4-glucanase A; Catalyzes endohydrolysis of 1,4-beta-D-glucosidic linkages in xyloglucan with retention of the beta-configuration of the glycosyl residues. Specific for xyloglucan and does not hydrolyze other cell wall components (By similarity). (238 aa)
galAProbable arabinogalactan endo-beta-1,4-galactanase A; Endogalactanase involved in the degradation of plant cell wall polysaccharides, and more particularly of hairy regions of pectin. (356 aa)
plyAProbable pectate lyase A; Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins. Favors pectate, the anion, over pectin, the methyl ester (By similarity); Belongs to the polysaccharide lyase 1 family. (321 aa)
pelBProbable pectin lyase B; Pectinolytic enzymes consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins (By similarity). (378 aa)
AFUA_2G01870Chitin synthase; Plays a major role in cell wall biogenesis. (933 aa)
plyDProbable pectate lyase D; Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins. Favors pectate, the anion, over pectin, the methyl ester (By similarity); Belongs to the polysaccharide lyase 3 family. (242 aa)
Your Current Organism:
Aspergillus fumigatus
NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293
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