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AFUA_4G10630 AFUA_4G10630 AFUA_4G10650 AFUA_4G10650 AFUA_4G13690 AFUA_4G13690 AFUA_2G04960 AFUA_2G04960 AFUA_2G00090 AFUA_2G00090 AFUA_7G00090 AFUA_7G00090 AFUA_8G00430 AFUA_8G00430 rvb2 rvb2 AFUA_8G07400 AFUA_8G07400 AFUA_7G04270 AFUA_7G04270 AFUA_5G12310 AFUA_5G12310 AFUA_7G04590 AFUA_7G04590 AFUA_7G05480 AFUA_7G05480 AFUA_6G10560 AFUA_6G10560 AFUA_6G10740 AFUA_6G10740 AFUA_1G03035 AFUA_1G03035 AFUA_2G15905 AFUA_2G15905 PIF1 PIF1 AFUA_5G15150 AFUA_5G15150 AFUA_6G14720 AFUA_6G14720 htb1 htb1 AFUA_3G15395 AFUA_3G15395 AFUA_1G13570 AFUA_1G13570 AFUA_5G06600 AFUA_5G06600 AFUA_2G18100 AFUA_2G18100 AFUA_2G16100 AFUA_2G16100 AFUA_2G12590 AFUA_2G12590 cbf5 cbf5 AFUA_2G06320 AFUA_2G06320
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AFUA_4G10630Sister chromatid cohesion protein Ctf8, putative. (162 aa)
AFUA_4G10650Uncharacterized protein. (198 aa)
AFUA_4G13690H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (198 aa)
AFUA_2G04960RecQ family helicase MusN. (1563 aa)
AFUA_2G00090Telomere-associated RecQ helicase, putative. (460 aa)
AFUA_7G00090Telomere-associated RecQ helicase, putative. (396 aa)
AFUA_8G00430EthD domain-containing protein. (157 aa)
rvb2RuvB-like helicase 2; DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity); Belongs to the RuvB family. (469 aa)
AFUA_8G07400Telomere-associated RecQ helicase, putative. (360 aa)
AFUA_7G042703'-5' exonuclease/helicase (Wrn), putative. (419 aa)
AFUA_5G12310Pseudouridine synthase. (403 aa)
AFUA_7G04590Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (1248 aa)
AFUA_7G05480Sister chromatid cohesion factor (Chl12), putative. (940 aa)
AFUA_6G10560DNA polymerase delta subunit 4, putative. (193 aa)
AFUA_6G10740Uncharacterized protein. (354 aa)
AFUA_1G03035HD superfamily hydrolase, putative. (243 aa)
AFUA_2G15905Sister chromatid cohesion protein Dcc1, putative. (394 aa)
PIF1ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (788 aa)
AFUA_5G15150Telomere-associated RecQ helicase, putative. (395 aa)
AFUA_6G14720Telomere-associated RecQ helicase, putative. (1445 aa)
htb1Histone H2B; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (140 aa)
AFUA_3G15395Telomere-associated RecQ helicase, putative. (714 aa)
AFUA_1G13570Small nuclear ribonucleoprotein complex protein Nhp2, putative. (323 aa)
AFUA_5G06600SNF2 family helicase/ATPase, putative. (1827 aa)
AFUA_2G18100Telomere-associated RecQ helicase, putative. (850 aa)
AFUA_2G16100Telomere-binding alpha subunit central domain protein. (635 aa)
AFUA_2G12590Lectin C-type domain protein. (597 aa)
cbf5H/ACA ribonucleoprotein complex subunit cbf5; Catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs and play a central role in ribosomal RNA processing. The H/ACA snoRNP complex also mediates pseudouridylation of other types of RNAs. Catalyzes pseudouridylation at position 93 in U2 snRNA. Also catalyzes pseudouridy [...] (487 aa)
AFUA_2G06320Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (529 aa)
Your Current Organism:
Aspergillus fumigatus
NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293
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