17 items (Aspergillus fumigatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AFUA_2G04960	RecQ family helicase MusN. (1563 aa)
	AFUA_2G06320	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (529 aa)
	AFUA_7G04270	3'-5' exonuclease/helicase (Wrn), putative. (419 aa)
	AFUA_8G07400	Telomere-associated RecQ helicase, putative. (360 aa)
	AFUA_8G00430	EthD domain-containing protein. (157 aa)
	AFUA_7G00090	Telomere-associated RecQ helicase, putative. (396 aa)
	AFUA_4G04760	Inositol kinase kinase (UvsB), putative; Belongs to the PI3/PI4-kinase family. (2449 aa)
	AFUA_5G15150	Telomere-associated RecQ helicase, putative. (395 aa)
	AFUA_5G13380	BRCT domain protein. (786 aa)
	AFUA_4G06970	RAD52 DNA repair protein RADC. (564 aa)
	AFUA_6G14720	Telomere-associated RecQ helicase, putative. (1445 aa)
	AFUA_3G15395	Telomere-associated RecQ helicase, putative. (714 aa)
	AFUA_3G08800	DUF1767 domain-containing protein. (249 aa)
	AFUA_1G05860	Uncharacterized protein. (404 aa)
	AFUA_2G00090	Telomere-associated RecQ helicase, putative. (460 aa)
	AFUA_2G02660	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (629 aa)
	AFUA_2G18100	Telomere-associated RecQ helicase, putative. (850 aa)

Your Current Organism:

Aspergillus fumigatus

NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFUA_1G05860	AFUA_2G00090	Q4WJI4	Q4WIZ8	Uncharacterized protein.	Telomere-associated RecQ helicase, putative.	0.567
AFUA_1G05860	AFUA_2G04960	Q4WJI4	Q4WHL6	Uncharacterized protein.	RecQ family helicase MusN.	0.567
AFUA_1G05860	AFUA_2G06320	Q4WJI4	Q4WH82	Uncharacterized protein.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.834
AFUA_1G05860	AFUA_2G18100	Q4WJI4	Q4WZ56	Uncharacterized protein.	Telomere-associated RecQ helicase, putative.	0.567
AFUA_1G05860	AFUA_3G08800	Q4WJI4	Q4WXA5	Uncharacterized protein.	DUF1767 domain-containing protein.	0.944
AFUA_1G05860	AFUA_3G15395	Q4WJI4	Q4WZ55	Uncharacterized protein.	Telomere-associated RecQ helicase, putative.	0.567
AFUA_1G05860	AFUA_4G04760	Q4WJI4	Q4W9I9	Uncharacterized protein.	Inositol kinase kinase (UvsB), putative; Belongs to the PI3/PI4-kinase family.	0.566
AFUA_1G05860	AFUA_4G06970	Q4WJI4	Q4WNU3	Uncharacterized protein.	RAD52 DNA repair protein RADC.	0.678
AFUA_1G05860	AFUA_5G13380	Q4WJI4	Q4WVU8	Uncharacterized protein.	BRCT domain protein.	0.497
AFUA_1G05860	AFUA_5G15150	Q4WJI4	Q4WWC1	Uncharacterized protein.	Telomere-associated RecQ helicase, putative.	0.567
AFUA_1G05860	AFUA_6G14720	Q4WJI4	Q4WL58	Uncharacterized protein.	Telomere-associated RecQ helicase, putative.	0.567
AFUA_1G05860	AFUA_7G00090	Q4WJI4	Q4WA55	Uncharacterized protein.	Telomere-associated RecQ helicase, putative.	0.567
AFUA_1G05860	AFUA_7G04270	Q4WJI4	Q4WG97	Uncharacterized protein.	3'-5' exonuclease/helicase (Wrn), putative.	0.996
AFUA_1G05860	AFUA_8G00430	Q4WJI4	Q4WAY9	Uncharacterized protein.	EthD domain-containing protein.	0.567
AFUA_1G05860	AFUA_8G07400	Q4WJI4	Q4WBN1	Uncharacterized protein.	Telomere-associated RecQ helicase, putative.	0.567
AFUA_2G00090	AFUA_1G05860	Q4WIZ8	Q4WJI4	Telomere-associated RecQ helicase, putative.	Uncharacterized protein.	0.567
AFUA_2G00090	AFUA_2G02660	Q4WIZ8	Q4WI92	Telomere-associated RecQ helicase, putative.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.717
AFUA_2G00090	AFUA_2G06320	Q4WIZ8	Q4WH82	Telomere-associated RecQ helicase, putative.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.661
AFUA_2G00090	AFUA_3G08800	Q4WIZ8	Q4WXA5	Telomere-associated RecQ helicase, putative.	DUF1767 domain-containing protein.	0.596
AFUA_2G00090	AFUA_4G04760	Q4WIZ8	Q4W9I9	Telomere-associated RecQ helicase, putative.	Inositol kinase kinase (UvsB), putative; Belongs to the PI3/PI4-kinase family.	0.627