17 items (Aspergillus fumigatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AFUA_5G13560	FHA domain protein. (610 aa)
	AFUA_5G13570	Uncharacterized protein. (292 aa)
	htb1	Histone H2B; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (140 aa)
	AFUA_3G11260	Ubiquitin (UbiC), putative. (154 aa)
	AFUA_2G14920	Protein kinase, putative. (1028 aa)
	AFUA_6G11410	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (784 aa)
	tel1	Serine/threonine-protein kinase tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability (By similarity). (2796 aa)
	AFUA_5G11170	Nucleosome remodeling complex ATPase subunit (Snf2h), putative. (986 aa)
	AFUA_4G13460	SNF2 family helicase/ATPase, putative. (1111 aa)
	AFUA_4G12680	DNA repair protein Rad50. (1312 aa)
	AFUA_4G06960	UBX domain protein, putative. (306 aa)
	AFUA_4G06170	BZIP domain-containing protein. (289 aa)
	AFUA_7G00530	NACHT and Ankyrin domain protein. (1334 aa)
	AFUA_7G03750	Cell-cycle checkpoint protein kinase, putative; Belongs to the protein kinase superfamily. (409 aa)
	esa1	Histone acetyltransferase esa1; Catalytic component of the NuA4 histone acetyltransferase (HAT) complex which is involved in epigenetic transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4, H3, H2B, H2A and H2A variant H2A.Z. Acetylates histone H4 to form H4K5ac, H4K8ac, H4K12ac and H4K16ac, histone H3 to form H3K14ac, histone H2B to form H2BK16ac, and histone H2A to form H2AK4ac and H2AK7ac. Acetylation of histone H4 is essential for DNA double- strand break repair through homologous recombination. Involved in cell cycle progression. Recru [...] (483 aa)
	AFUA_2G02420	Cytoplasm to vacuole targeting Vps64, putative. (741 aa)
	AFUA_2G01670	FHA domain protein. (724 aa)

Your Current Organism:

Aspergillus fumigatus

NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFUA_2G01670	AFUA_3G11260	Q4WIJ1	Q4WXZ8	FHA domain protein.	Ubiquitin (UbiC), putative.	0.504
AFUA_2G01670	AFUA_4G06170	Q4WIJ1	Q4WNL5	FHA domain protein.	BZIP domain-containing protein.	0.504
AFUA_2G02420	AFUA_3G11260	Q4WIB6	Q4WXZ8	Cytoplasm to vacuole targeting Vps64, putative.	Ubiquitin (UbiC), putative.	0.504
AFUA_2G02420	AFUA_4G06170	Q4WIB6	Q4WNL5	Cytoplasm to vacuole targeting Vps64, putative.	BZIP domain-containing protein.	0.504
AFUA_2G14920	AFUA_4G12680	Q4X028	Q4WQF8	Protein kinase, putative.	DNA repair protein Rad50.	0.497
AFUA_2G14920	AFUA_6G11410	Q4X028	Q4WM28	Protein kinase, putative.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.578
AFUA_2G14920	tel1	Q4X028	Q4WVM7	Protein kinase, putative.	Serine/threonine-protein kinase tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability (By similarity).	0.849
AFUA_3G11260	AFUA_2G01670	Q4WXZ8	Q4WIJ1	Ubiquitin (UbiC), putative.	FHA domain protein.	0.504
AFUA_3G11260	AFUA_2G02420	Q4WXZ8	Q4WIB6	Ubiquitin (UbiC), putative.	Cytoplasm to vacuole targeting Vps64, putative.	0.504
AFUA_3G11260	AFUA_4G06960	Q4WXZ8	Q4WNU2	Ubiquitin (UbiC), putative.	UBX domain protein, putative.	0.492
AFUA_3G11260	AFUA_5G13560	Q4WXZ8	Q4WVW6	Ubiquitin (UbiC), putative.	FHA domain protein.	0.504
AFUA_3G11260	AFUA_5G13570	Q4WXZ8	Q4WVW7	Ubiquitin (UbiC), putative.	Uncharacterized protein.	0.504
AFUA_3G11260	AFUA_6G11410	Q4WXZ8	Q4WM28	Ubiquitin (UbiC), putative.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.490
AFUA_3G11260	htb1	Q4WXZ8	Q4WWC5	Ubiquitin (UbiC), putative.	Histone H2B; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.758
AFUA_4G06170	AFUA_2G01670	Q4WNL5	Q4WIJ1	BZIP domain-containing protein.	FHA domain protein.	0.504
AFUA_4G06170	AFUA_2G02420	Q4WNL5	Q4WIB6	BZIP domain-containing protein.	Cytoplasm to vacuole targeting Vps64, putative.	0.504
AFUA_4G06170	AFUA_4G06960	Q4WNL5	Q4WNU2	BZIP domain-containing protein.	UBX domain protein, putative.	0.492
AFUA_4G06170	AFUA_5G13560	Q4WNL5	Q4WVW6	BZIP domain-containing protein.	FHA domain protein.	0.504
AFUA_4G06170	AFUA_5G13570	Q4WNL5	Q4WVW7	BZIP domain-containing protein.	Uncharacterized protein.	0.504
AFUA_4G06170	AFUA_6G11410	Q4WNL5	Q4WM28	BZIP domain-containing protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.490