STRINGSTRING
AFUA_2G00090 AFUA_2G00090 AFUA_5G13220 AFUA_5G13220 AFUA_5G12010 AFUA_5G12010 AFUA_5G11840 AFUA_5G11840 AFUA_5G11370 AFUA_5G11370 AFUA_5G08480 AFUA_5G08480 AFUA_5G05960 AFUA_5G05960 AFUA_1G10410 AFUA_1G10410 AFUA_1G12520 AFUA_1G12520 AFUA_4G12610 AFUA_4G12610 AFUA_4G06970 AFUA_4G06970 AFUA_4G06170 AFUA_4G06170 AFUA_6G10560 AFUA_6G10560 AFUA_6G13160 AFUA_6G13160 AFUA_6G14720 AFUA_6G14720 AFUA_1G05860 AFUA_1G05860 AFUA_2G01670 AFUA_2G01670 csm3 csm3 AFUA_4G04760 AFUA_4G04760 tof1 tof1 AFUA_7G00090 AFUA_7G00090 AFUA_2G02420 AFUA_2G02420 AFUA_8G00430 AFUA_8G00430 AFUA_8G07400 AFUA_8G07400 slx1 slx1 AFUA_7G04270 AFUA_7G04270 AFUA_7G04550 AFUA_7G04550 AFUA_7G05890 AFUA_7G05890 AFUA_2G06320 AFUA_2G06320 AFUA_2G05650 AFUA_2G05650 AFUA_2G04960 AFUA_2G04960 AFUA_2G02660 AFUA_2G02660 AFUA_2G18100 AFUA_2G18100 AFUA_3G15395 AFUA_3G15395 AFUA_3G14460 AFUA_3G14460 AFUA_3G13260 AFUA_3G13260 mus81 mus81 AFUA_3G11260 AFUA_3G11260 AFUA_3G10530 AFUA_3G10530 AFUA_3G08800 AFUA_3G08800 htb1 htb1 AFUA_5G15150 AFUA_5G15150 AFUA_5G13570 AFUA_5G13570 AFUA_5G13560 AFUA_5G13560 AFUA_5G13380 AFUA_5G13380
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AFUA_2G00090Telomere-associated RecQ helicase, putative. (460 aa)
AFUA_5G13220ERCC4 domain-containing protein. (649 aa)
AFUA_5G12010Serine/threonine-protein phosphatase. (474 aa)
AFUA_5G11840Protein kinase, putative. (825 aa)
AFUA_5G11370Serine/threonine-protein phosphatase. (340 aa)
AFUA_5G08480Serine/threonine protein kinase, putative. (618 aa)
AFUA_5G05960Serine/threonine protein kinase, putative. (544 aa)
AFUA_1G10410DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (348 aa)
AFUA_1G12520DNA repair protein (Rad57), putative. (647 aa)
AFUA_4G12610Uncharacterized protein. (387 aa)
AFUA_4G06970RAD52 DNA repair protein RADC. (564 aa)
AFUA_4G06170BZIP domain-containing protein. (289 aa)
AFUA_6G10560DNA polymerase delta subunit 4, putative. (193 aa)
AFUA_6G13160Serine/threonine protein kinase, putative. (514 aa)
AFUA_6G14720Telomere-associated RecQ helicase, putative. (1445 aa)
AFUA_1G05860Uncharacterized protein. (404 aa)
AFUA_2G01670FHA domain protein. (724 aa)
csm3Chromosome segregation in meiosis protein 3; Forms a fork protection complex (FPC) with tof1 and which is required for chromosome segregation during meiosis and DNA damage repair. FPC coordinates leading and lagging strand synthesis and moves with the replication fork. FPC stabilizes replication forks in a configuration that is recognized by replication checkpoint sensors (By similarity). (270 aa)
AFUA_4G04760Inositol kinase kinase (UvsB), putative; Belongs to the PI3/PI4-kinase family. (2449 aa)
tof1Topoisomerase 1-associated factor 1; Forms a fork protection complex (FPC) with csm3 and which is required for chromosome segregation during meiosis and DNA damage repair. FPC coordinates leading and lagging strand synthesis and moves with the replication fork. FPC stabilizes replication forks in a configuration that is recognized by replication checkpoint sensors (By similarity). (1176 aa)
AFUA_7G00090Telomere-associated RecQ helicase, putative. (396 aa)
AFUA_2G02420Cytoplasm to vacuole targeting Vps64, putative. (741 aa)
AFUA_8G00430EthD domain-containing protein. (157 aa)
AFUA_8G07400Telomere-associated RecQ helicase, putative. (360 aa)
slx1Structure-specific endonuclease subunit slx1; Catalytic subunit of the slx1-slx4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (423 aa)
AFUA_7G042703'-5' exonuclease/helicase (Wrn), putative. (419 aa)
AFUA_7G04550Serine/threonine protein kinase, putative. (389 aa)
AFUA_7G05890Uncharacterized protein. (252 aa)
AFUA_2G06320Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (529 aa)
AFUA_2G05650Cytoplasmic asparaginyl-tRNA synthetase, putative. (574 aa)
AFUA_2G04960RecQ family helicase MusN. (1563 aa)
AFUA_2G02660DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (629 aa)
AFUA_2G18100Telomere-associated RecQ helicase, putative. (850 aa)
AFUA_3G15395Telomere-associated RecQ helicase, putative. (714 aa)
AFUA_3G14460Rad51 family DNA repair protein, putative. (456 aa)
AFUA_3G13260Rad2-like endonuclease, putative. (869 aa)
mus81Crossover junction endonuclease mus81; Interacts with eme1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single- end invasion (SEI) (By similarity); Belongs to the XPF family. (596 aa)
AFUA_3G11260Ubiquitin (UbiC), putative. (154 aa)
AFUA_3G10530Protein serine/threonine kinase (Ran1), putative; Belongs to the protein kinase superfamily. (423 aa)
AFUA_3G08800DUF1767 domain-containing protein. (249 aa)
htb1Histone H2B; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (140 aa)
AFUA_5G15150Telomere-associated RecQ helicase, putative. (395 aa)
AFUA_5G13570Uncharacterized protein. (292 aa)
AFUA_5G13560FHA domain protein. (610 aa)
AFUA_5G13380BRCT domain protein. (786 aa)
Your Current Organism:
Aspergillus fumigatus
NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293
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