STRINGSTRING
AFUA_2G00090 AFUA_2G00090 AFUA_1G12520 AFUA_1G12520 AFUA_5G13220 AFUA_5G13220 AFUA_5G15150 AFUA_5G15150 mus81 mus81 AFUA_3G13260 AFUA_3G13260 AFUA_3G14460 AFUA_3G14460 AFUA_3G15395 AFUA_3G15395 AFUA_2G18100 AFUA_2G18100 AFUA_7G00090 AFUA_7G00090 AFUA_8G00430 AFUA_8G00430 AFUA_8G07400 AFUA_8G07400 slx1 slx1 AFUA_7G05890 AFUA_7G05890 AFUA_2G05650 AFUA_2G05650 AFUA_2G04960 AFUA_2G04960 AFUA_2G02660 AFUA_2G02660
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AFUA_2G00090Telomere-associated RecQ helicase, putative. (460 aa)
AFUA_1G12520DNA repair protein (Rad57), putative. (647 aa)
AFUA_5G13220ERCC4 domain-containing protein. (649 aa)
AFUA_5G15150Telomere-associated RecQ helicase, putative. (395 aa)
mus81Crossover junction endonuclease mus81; Interacts with eme1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single- end invasion (SEI) (By similarity); Belongs to the XPF family. (596 aa)
AFUA_3G13260Rad2-like endonuclease, putative. (869 aa)
AFUA_3G14460Rad51 family DNA repair protein, putative. (456 aa)
AFUA_3G15395Telomere-associated RecQ helicase, putative. (714 aa)
AFUA_2G18100Telomere-associated RecQ helicase, putative. (850 aa)
AFUA_7G00090Telomere-associated RecQ helicase, putative. (396 aa)
AFUA_8G00430EthD domain-containing protein. (157 aa)
AFUA_8G07400Telomere-associated RecQ helicase, putative. (360 aa)
slx1Structure-specific endonuclease subunit slx1; Catalytic subunit of the slx1-slx4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (423 aa)
AFUA_7G05890Uncharacterized protein. (252 aa)
AFUA_2G05650Cytoplasmic asparaginyl-tRNA synthetase, putative. (574 aa)
AFUA_2G04960RecQ family helicase MusN. (1563 aa)
AFUA_2G02660DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (629 aa)
Your Current Organism:
Aspergillus fumigatus
NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293
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