STRINGSTRING
AFUA_4G04760 AFUA_4G04760 AFUA_2G15220 AFUA_2G15220 AFUA_3G11260 AFUA_3G11260 AFUA_3G10460 AFUA_3G10460 AFUA_4G06170 AFUA_4G06170 AFUA_2G05650 AFUA_2G05650 AFUA_2G06320 AFUA_2G06320 AFUA_7G05280 AFUA_7G05280 slx1 slx1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AFUA_4G04760Inositol kinase kinase (UvsB), putative; Belongs to the PI3/PI4-kinase family. (2449 aa)
AFUA_2G15220DNA repair protein Pso2/Snm1, putative. (850 aa)
AFUA_3G11260Ubiquitin (UbiC), putative. (154 aa)
AFUA_3G10460Nuclear transport factor NTF-2, putative. (124 aa)
AFUA_4G06170BZIP domain-containing protein. (289 aa)
AFUA_2G05650Cytoplasmic asparaginyl-tRNA synthetase, putative. (574 aa)
AFUA_2G06320Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (529 aa)
AFUA_7G05280Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (822 aa)
slx1Structure-specific endonuclease subunit slx1; Catalytic subunit of the slx1-slx4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (423 aa)
Your Current Organism:
Aspergillus fumigatus
NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.