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AFUA_8G07400 AFUA_8G07400 AFUA_5G01700 AFUA_5G01700 AFUA_8G04810 AFUA_8G04810 AFUA_2G14920 AFUA_2G14920 AFUA_2G18100 AFUA_2G18100 AFUA_3G15395 AFUA_3G15395 bud32 bud32 AFUA_3G11260 AFUA_3G11260 AFUA_3G08800 AFUA_3G08800 AFUA_5G15150 AFUA_5G15150 AFUA_5G13380 AFUA_5G13380 AFUA_5G11840 AFUA_5G11840 AFUA_5G08480 AFUA_5G08480 AFUA_5G05960 AFUA_5G05960 AFUA_1G09950 AFUA_1G09950 AFUA_1G16330 AFUA_1G16330 AFUA_4G12400 AFUA_4G12400 mdm34 mdm34 AFUA_4G06180 AFUA_4G06180 AFUA_4G06170 AFUA_4G06170 AFUA_6G13160 AFUA_6G13160 AFUA_6G14720 AFUA_6G14720 AFUA_1G05860 AFUA_1G05860 spt16 spt16 AFUA_2G00090 AFUA_2G00090 AFUA_2G01520 AFUA_2G01520 AFUA_2G02660 AFUA_2G02660 AFUA_2G04960 AFUA_2G04960 AFUA_2G06320 AFUA_2G06320 pob3 pob3 AFUA_7G04550 AFUA_7G04550 AFUA_7G04270 AFUA_7G04270 AFUA_7G03750 AFUA_7G03750 AFUA_4G06085 AFUA_4G06085 AFUA_4G04760 AFUA_4G04760 AFUA_7G00090 AFUA_7G00090 AFUA_8G00430 AFUA_8G00430
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AFUA_8G07400Telomere-associated RecQ helicase, putative. (360 aa)
AFUA_5G01700Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit. (662 aa)
AFUA_8G04810Casein kinase, putative; Belongs to the protein kinase superfamily. (336 aa)
AFUA_2G14920Protein kinase, putative. (1028 aa)
AFUA_2G18100Telomere-associated RecQ helicase, putative. (850 aa)
AFUA_3G15395Telomere-associated RecQ helicase, putative. (714 aa)
bud32EKC/KEOPS complex subunit bud32; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. BUD32 has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit KAE1. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is r [...] (277 aa)
AFUA_3G11260Ubiquitin (UbiC), putative. (154 aa)
AFUA_3G08800DUF1767 domain-containing protein. (249 aa)
AFUA_5G15150Telomere-associated RecQ helicase, putative. (395 aa)
AFUA_5G13380BRCT domain protein. (786 aa)
AFUA_5G11840Protein kinase, putative. (825 aa)
AFUA_5G08480Serine/threonine protein kinase, putative. (618 aa)
AFUA_5G05960Serine/threonine protein kinase, putative. (544 aa)
AFUA_1G09950Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (294 aa)
AFUA_1G16330Ribosome assembly protein Noc2, putative. (788 aa)
AFUA_4G12400PHD finger domain protein, putative. (836 aa)
mdm34Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. Mdm34 is required for the interaction of the ER-resident membrane protein mmm1 and the outer mitochondrial membrane-resident beta-barrel protein mdm10. (572 aa)
AFUA_4G06180Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (364 aa)
AFUA_4G06170BZIP domain-containing protein. (289 aa)
AFUA_6G13160Serine/threonine protein kinase, putative. (514 aa)
AFUA_6G14720Telomere-associated RecQ helicase, putative. (1445 aa)
AFUA_1G05860Uncharacterized protein. (404 aa)
spt16FACT complex subunit spt16; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (1019 aa)
AFUA_2G00090Telomere-associated RecQ helicase, putative. (460 aa)
AFUA_2G01520Protein kinase, putative. (1314 aa)
AFUA_2G02660DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (629 aa)
AFUA_2G04960RecQ family helicase MusN. (1563 aa)
AFUA_2G06320Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (529 aa)
pob3FACT complex subunit pob3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (573 aa)
AFUA_7G04550Serine/threonine protein kinase, putative. (389 aa)
AFUA_7G042703'-5' exonuclease/helicase (Wrn), putative. (419 aa)
AFUA_7G03750Cell-cycle checkpoint protein kinase, putative; Belongs to the protein kinase superfamily. (409 aa)
AFUA_4G06085Uncharacterized protein. (435 aa)
AFUA_4G04760Inositol kinase kinase (UvsB), putative; Belongs to the PI3/PI4-kinase family. (2449 aa)
AFUA_7G00090Telomere-associated RecQ helicase, putative. (396 aa)
AFUA_8G00430EthD domain-containing protein. (157 aa)
Your Current Organism:
Aspergillus fumigatus
NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293
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