STRINGSTRING
AFUA_5G12895 AFUA_5G12895 AFUA_4G11602 AFUA_4G11602 AFUA_1G11410 AFUA_1G11410 AFUA_1G12475 AFUA_1G12475 AFUA_8G04240 AFUA_8G04240 AFUA_6G05040 AFUA_6G05040 AFUA_5G01870 AFUA_5G01870 AFUA_5G02520 AFUA_5G02520 AFUA_5G04130 AFUA_5G04130 AFUA_7G04310 AFUA_7G04310 AFUA_2G06320 AFUA_2G06320 AFUA_2G06190 AFUA_2G06190 AFUA_2G03920 AFUA_2G03920 AFUA_1G05670 AFUA_1G05670 AFUA_1G05350 AFUA_1G05350 AFUA_1G04910 AFUA_1G04910 AFUA_1G04900 AFUA_1G04900 AFUA_1G03920 AFUA_1G03920 AFUA_1G03410 AFUA_1G03410 AFUA_1G02500 AFUA_1G02500 AFUA_6G11130 AFUA_6G11130 AFUA_6G10560 AFUA_6G10560 AFUA_6G10490 AFUA_6G10490 AFUA_6G09180 AFUA_6G09180 AFUA_6G08210 AFUA_6G08210 AFUA_6G07980 AFUA_6G07980 AFUA_6G07890 AFUA_6G07890 AFUA_4G06170 AFUA_4G06170 AFUA_4G07970 AFUA_4G07970 psf3 psf3 AFUA_4G12160 AFUA_4G12160 AFUA_4G12210 AFUA_4G12210 AFUA_4G12430 AFUA_4G12430 AFUA_4G13160 AFUA_4G13160 AFUA_1G15310 AFUA_1G15310 AFUA_1G10720 AFUA_1G10720 AFUA_1G10550 AFUA_1G10550 AFUA_5G05790 AFUA_5G05790 AFUA_5G08110 AFUA_5G08110 AFUA_5G10620 AFUA_5G10620 AFUA_5G10890 AFUA_5G10890 AFUA_5G13020 AFUA_5G13020 AFUA_5G13730 AFUA_5G13730 AFUA_5G14820 AFUA_5G14820 htb1 htb1 AFUA_3G05540 AFUA_3G05540 fen1 fen1 AFUA_3G08300 AFUA_3G08300 AFUA_3G09020 AFUA_3G09020 pol2 pol2 AFUA_3G10280 AFUA_3G10280 AFUA_3G11140 AFUA_3G11140 AFUA_3G11260 AFUA_3G11260 AFUA_3G12690 AFUA_3G12690 AFUA_3G14010 AFUA_3G14010 AFUA_2G17190 AFUA_2G17190 AFUA_2G16710 AFUA_2G16710 AFUA_2G16600 AFUA_2G16600 AFUA_2G16150 AFUA_2G16150 AFUA_2G16090 AFUA_2G16090 AFUA_2G13210 AFUA_2G13210 AFUA_2G12250 AFUA_2G12250 AFUA_2G12220 AFUA_2G12220 AFUA_2G11170 AFUA_2G11170 psf2 psf2 AFUA_2G10730 AFUA_2G10730 MCM7 MCM7 AFUA_2G09060 AFUA_2G09060 AFUA_2G09010 AFUA_2G09010
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AFUA_5G12895SsDNA binding protein Ssb3, putative. (122 aa)
AFUA_4G11602Cnn_1N domain-containing protein. (987 aa)
AFUA_1G11410Ubiquitin conjugating enzyme E2, putative; Belongs to the ubiquitin-conjugating enzyme family. (427 aa)
AFUA_1G12475Uncharacterized protein. (145 aa)
AFUA_8G04240Origin recognition complex subunit 3, putative. (698 aa)
AFUA_6G05040DNA replication factor C subunit Rfc4, putative. (348 aa)
AFUA_5G01870DNA replication factor C subunit Rfc3, putative. (396 aa)
AFUA_5G02520DNA helicase; Belongs to the MCM family. (718 aa)
AFUA_5G04130Cyclin-dependent protein kinase PhoA; Belongs to the protein kinase superfamily. (389 aa)
AFUA_7G04310Cell division control protein; Belongs to the CDC6/cdc18 family. (647 aa)
AFUA_2G06320Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (529 aa)
AFUA_2G06190DNA polymerase epsilon subunit B, putative. (762 aa)
AFUA_2G03920G1/S-specific cyclin Cln1, putative; Belongs to the cyclin family. (416 aa)
AFUA_1G05670Uncharacterized protein. (678 aa)
AFUA_1G05350Uncharacterized protein. (125 aa)
AFUA_1G04910Vezatin domain-containing protein. (629 aa)
AFUA_1G04900Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (219 aa)
AFUA_1G03920DNA helicase; Belongs to the MCM family. (892 aa)
AFUA_1G03410DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (500 aa)
AFUA_1G02500Origin recognition complex subunit Orc5, putative. (541 aa)
AFUA_6G11130Possible replication factor-a protein. (289 aa)
AFUA_6G10560DNA polymerase delta subunit 4, putative. (193 aa)
AFUA_6G10490Uncharacterized protein. (441 aa)
AFUA_6G09180G1/S regulator NimO, putative. (650 aa)
AFUA_6G08210DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (266 aa)
AFUA_6G07980Cell division control protein 2 kinase, putative; Belongs to the protein kinase superfamily. (323 aa)
AFUA_6G07890Telomere silencing protein Zds1, putative. (857 aa)
AFUA_4G06170BZIP domain-containing protein. (289 aa)
AFUA_4G07970DNA polymerase delta subunit 2, putative. (554 aa)
psf3DNA replication complex GINS protein psf3; The GINS complex plays an essential role in the initiation of DNA replication. (178 aa)
AFUA_4G12160G2/M-specific cyclin NimE; Belongs to the cyclin family. (499 aa)
AFUA_4G12210DNA replication helicase Dna2, putative. (1657 aa)
AFUA_4G12430PSF1 domain protein. (253 aa)
AFUA_4G13160TPR domain protein. (477 aa)
AFUA_1G15310DNA replication initiation factor Cdc45. (860 aa)
AFUA_1G10720Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (789 aa)
AFUA_1G10550CBF/NF-Y family transcription factor, putative. (282 aa)
AFUA_5G05790Ubiquitin ligase subunit HrtA, putative. (120 aa)
AFUA_5G08110Origin recognition complex subunit 2, putative. (559 aa)
AFUA_5G10620Histone-like transcription factor, putative. (190 aa)
AFUA_5G10890DNA helicase; Belongs to the MCM family. (956 aa)
AFUA_5G13020DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (617 aa)
AFUA_5G13730NlpC/P60-like cell-wall peptidase, putative. (359 aa)
AFUA_5G14820Replication factor C subunit. (389 aa)
htb1Histone H2B; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (140 aa)
AFUA_3G05540Cell cycle protein kinase, putative. (464 aa)
fen1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (395 aa)
AFUA_3G08300DNA replication factor C subunit Rfc2, putative. (394 aa)
AFUA_3G09020DNA primase; Belongs to the eukaryotic-type primase small subunit family. (522 aa)
pol2DNA polymerase epsilon catalytic subunit A; DNA polymerase II participates in chromosomal DNA replication. (2230 aa)
AFUA_3G10280DNA replication protein, putative. (792 aa)
AFUA_3G11140DNA ligase. (833 aa)
AFUA_3G11260Ubiquitin (UbiC), putative. (154 aa)
AFUA_3G12690Uncharacterized protein. (543 aa)
AFUA_3G14010DNA helicase; Belongs to the MCM family. (896 aa)
AFUA_2G17190AAA domain-containing protein. (1129 aa)
AFUA_2G16710Uncharacterized protein. (438 aa)
AFUA_2G16600DNA polymerase. (1105 aa)
AFUA_2G16150G2/mitotic-specific cyclin (Clb3), putative; Belongs to the cyclin family. (636 aa)
AFUA_2G16090Importin subunit alpha; Belongs to the importin alpha family. (552 aa)
AFUA_2G13210DnaJ domain protein. (323 aa)
AFUA_2G12250DNA replication factor C subunit Rfc5, putative. (294 aa)
AFUA_2G12220Replication factor C subunit 1. (1085 aa)
AFUA_2G11170Origin recognition complex subunit Orc4, putative. (704 aa)
psf2DNA replication complex GINS protein psf2; The GINS complex plays an essential role in the initiation of DNA replication. Has a role in chromosome segregation (By similarity). (271 aa)
AFUA_2G10730DNA polymerase. (1462 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (854 aa)
AFUA_2G09060DNA helicase; Belongs to the MCM family. (1023 aa)
AFUA_2G09010DNA ligase. (909 aa)
Your Current Organism:
Aspergillus fumigatus
NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293
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