(36 nodes) RNA Polymerase II Transcription Termination network (Aspergillus fumigatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AFUA_4G04330	THO complex subunit Tho1, putative. (673 aa)
	AFUA_7G01930	GTP-binding protein EsdC. (261 aa)
	AFUA_8G05260	Nucleic acid-binding protein. (324 aa)
	AFUA_8G04960	Small nuclear ribonucleoprotein G. (78 aa)
	AFUA_5G01940	R3H domain protein, putative. (607 aa)
	AFUA_5G02030	Cleavage and polyadenylation specific factor 5. (334 aa)
	AFUA_5G02280	Endo-1,3(4)-beta-glucanase, putative. (391 aa)
	AFUA_3G02380	U2 auxiliary factor small subunit, putative. (209 aa)
	AFUA_3G00350	Uncharacterized protein. (107 aa)
	AFUA_7G05310	U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family. (563 aa)
	AFUA_7G05980	Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (95 aa)
	AFUA_1G07510	mRNA cleavage factor complex component Pcf11, putative. (654 aa)
	AFUA_1G06490	Uncharacterized protein. (486 aa)
	AFUA_1G03820	mRNA splicing factor RNA helicase (Prp16), putative. (915 aa)
	fip1	Pre-mRNA polyadenylation factor fip1; Pre-mRNA polyadenylation factor that directly interacts with poly(A) polymerase; Belongs to the FIP1 family. (338 aa)
	AFUA_6G07300	mRNA splicing factor (Prp17), putative. (580 aa)
	AFUA_4G10240	Small nuclear ribonucleoprotein Sm D3. (116 aa)
	AFUA_4G10260	Uncharacterized protein. (448 aa)
	AFUA_4G12190	WD repeat-containing protein. (408 aa)
	AFUA_1G15340	Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. (580 aa)
	AFUA_1G09490	RNP domain protein. (215 aa)
	slu7	Pre-mRNA-splicing factor slu7; Involved in pre-mRNA splicing. (476 aa)
	AFUA_3G08120	PWI domain mRNA processing protein, putative. (533 aa)
	AFUA_3G10100	Pre-RNA splicing factor Srp2, putative. (272 aa)
	rna14	mRNA 3'-end-processing protein rna14; Component of the cleavage factor IA (CFIA) complex, which is involved in the endonucleolytic cleavage during polyadenylation- dependent pre-mRNA 3'-end formation. (1029 aa)
	AFUA_3G11580	Uncharacterized protein. (358 aa)
	AFUA_3G12940	C6 transcription factor, putative. (754 aa)
	AFUA_2G15510	DUF866 domain protein. (160 aa)
	AFUA_2G15500	Small nuclear ribonucleoprotein SmF, putative. (88 aa)
	AFUA_2G13820	SAP domain protein, putative. (302 aa)
	AFUA_2G09100	Polyadenylation factor subunit CstF64, putative. (296 aa)
	AFUA_2G08210	Uncharacterized protein. (337 aa)
	AFUA_5G09010	Conserved glutamic acid rich protein. (609 aa)
	clp1	mRNA cleavage and polyadenylation factor clp1; Required for endonucleolytic cleavage during polyadenylation- dependent pre-mRNA 3'-end formation. (552 aa)
	AFUA_6G07170	Uncharacterized protein. (212 aa)
	spp2	Pre-mRNA-splicing factor spp2; Involved in spliceosome maturation and the first step of pre- mRNA splicing. (541 aa)

Your Current Organism:

Aspergillus fumigatus

NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFUA_1G03820	AFUA_1G06490	Q4WK38	Q4WJC2	mRNA splicing factor RNA helicase (Prp16), putative.	Uncharacterized protein.	0.606
AFUA_1G03820	AFUA_1G09490	Q4WK38	Q4WTF4	mRNA splicing factor RNA helicase (Prp16), putative.	RNP domain protein.	0.953
AFUA_1G03820	AFUA_1G15340	Q4WK38	Q4WRR8	mRNA splicing factor RNA helicase (Prp16), putative.	Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's.	0.775
AFUA_1G03820	AFUA_2G08210	Q4WK38	Q4X1Z8	mRNA splicing factor RNA helicase (Prp16), putative.	Uncharacterized protein.	0.595
AFUA_1G03820	AFUA_2G13820	Q4WK38	Q4X0D8	mRNA splicing factor RNA helicase (Prp16), putative.	SAP domain protein, putative.	0.502
AFUA_1G03820	AFUA_2G15500	Q4WK38	Q4WZW8	mRNA splicing factor RNA helicase (Prp16), putative.	Small nuclear ribonucleoprotein SmF, putative.	0.862
AFUA_1G03820	AFUA_2G15510	Q4WK38	Q4WZW7	mRNA splicing factor RNA helicase (Prp16), putative.	DUF866 domain protein.	0.691
AFUA_1G03820	AFUA_3G00350	Q4WK38	Q4WG08	mRNA splicing factor RNA helicase (Prp16), putative.	Uncharacterized protein.	0.502
AFUA_1G03820	AFUA_3G02380	Q4WK38	Q4WFF4	mRNA splicing factor RNA helicase (Prp16), putative.	U2 auxiliary factor small subunit, putative.	0.781
AFUA_1G03820	AFUA_3G08120	Q4WK38	Q4WX39	mRNA splicing factor RNA helicase (Prp16), putative.	PWI domain mRNA processing protein, putative.	0.885
AFUA_1G03820	AFUA_3G10100	Q4WK38	Q4WXN1	mRNA splicing factor RNA helicase (Prp16), putative.	Pre-RNA splicing factor Srp2, putative.	0.819
AFUA_1G03820	AFUA_3G11580	Q4WK38	Q4WY30	mRNA splicing factor RNA helicase (Prp16), putative.	Uncharacterized protein.	0.637
AFUA_1G03820	AFUA_3G12940	Q4WK38	Q4WYG4	mRNA splicing factor RNA helicase (Prp16), putative.	C6 transcription factor, putative.	0.606
AFUA_1G03820	AFUA_4G04330	Q4WK38	Q4W9N3	mRNA splicing factor RNA helicase (Prp16), putative.	THO complex subunit Tho1, putative.	0.623
AFUA_1G03820	AFUA_4G10240	Q4WK38	Q4WPS0	mRNA splicing factor RNA helicase (Prp16), putative.	Small nuclear ribonucleoprotein Sm D3.	0.734
AFUA_1G03820	AFUA_4G10260	Q4WK38	Q4WPS2	mRNA splicing factor RNA helicase (Prp16), putative.	Uncharacterized protein.	0.734
AFUA_1G03820	AFUA_4G12190	Q4WK38	Q4WQB0	mRNA splicing factor RNA helicase (Prp16), putative.	WD repeat-containing protein.	0.594
AFUA_1G03820	AFUA_5G02030	Q4WK38	Q4WE76	mRNA splicing factor RNA helicase (Prp16), putative.	Cleavage and polyadenylation specific factor 5.	0.625
AFUA_1G03820	AFUA_5G02280	Q4WK38	Q4WEA1	mRNA splicing factor RNA helicase (Prp16), putative.	Endo-1,3(4)-beta-glucanase, putative.	0.707
AFUA_1G03820	AFUA_5G09010	Q4WK38	Q4WUM8	mRNA splicing factor RNA helicase (Prp16), putative.	Conserved glutamic acid rich protein.	0.636