(8 nodes) RHOQ GTPase cycle network (Aspergillus fumigatus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

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co-expression

protein homology

Your Input:
	hulA	Probable E3 ubiquitin-protein ligase hulA; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Probably involved in the regulatory network controlling carbon source utilization. (813 aa)
	AFUA_2G13760	Plasma membrane SNARE protein (Sec9), putative. (421 aa)
	AFUA_1G03740	Glutamate carboxypeptidase, putative. (774 aa)
	AFUA_2G03640	Ras GTPase activating protein, putative. (1750 aa)
	ste20	Serine/threonine-protein kinase ste20; MAP4K component of the MAPK pathway required for the mating pheromone response and the regulation of cell polarity and cell cycle. Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. (815 aa)
	AFUA_2G05740	Rho GTPase ModA, putative. (192 aa)
	AFUA_1G02540	EF hand domain protein. (1258 aa)
	AFUA_5G05900	Non-specific serine/threonine protein kinase. (836 aa)

Your Current Organism:

Aspergillus fumigatus

NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFUA_1G02540	AFUA_2G05740	Q4WKG6	Q4WHE0	EF hand domain protein.	Rho GTPase ModA, putative.	0.622
AFUA_2G03640	AFUA_2G05740	Q4WHZ6	Q4WHE0	Ras GTPase activating protein, putative.	Rho GTPase ModA, putative.	0.917
AFUA_2G03640	AFUA_5G05900	Q4WHZ6	Q4WTS2	Ras GTPase activating protein, putative.	Non-specific serine/threonine protein kinase.	0.514
AFUA_2G03640	hulA	Q4WHZ6	Q4WTF3	Ras GTPase activating protein, putative.	Probable E3 ubiquitin-protein ligase hulA; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Probably involved in the regulatory network controlling carbon source utilization.	0.592
AFUA_2G03640	ste20	Q4WHZ6	Q4WHP3	Ras GTPase activating protein, putative.	Serine/threonine-protein kinase ste20; MAP4K component of the MAPK pathway required for the mating pheromone response and the regulation of cell polarity and cell cycle. Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.	0.514
AFUA_2G05740	AFUA_1G02540	Q4WHE0	Q4WKG6	Rho GTPase ModA, putative.	EF hand domain protein.	0.622
AFUA_2G05740	AFUA_2G03640	Q4WHE0	Q4WHZ6	Rho GTPase ModA, putative.	Ras GTPase activating protein, putative.	0.917
AFUA_2G05740	AFUA_2G13760	Q4WHE0	Q4X0E4	Rho GTPase ModA, putative.	Plasma membrane SNARE protein (Sec9), putative.	0.479
AFUA_2G05740	AFUA_5G05900	Q4WHE0	Q4WTS2	Rho GTPase ModA, putative.	Non-specific serine/threonine protein kinase.	0.989
AFUA_2G05740	hulA	Q4WHE0	Q4WTF3	Rho GTPase ModA, putative.	Probable E3 ubiquitin-protein ligase hulA; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Probably involved in the regulatory network controlling carbon source utilization.	0.587
AFUA_2G05740	ste20	Q4WHE0	Q4WHP3	Rho GTPase ModA, putative.	Serine/threonine-protein kinase ste20; MAP4K component of the MAPK pathway required for the mating pheromone response and the regulation of cell polarity and cell cycle. Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.	0.989
AFUA_2G13760	AFUA_2G05740	Q4X0E4	Q4WHE0	Plasma membrane SNARE protein (Sec9), putative.	Rho GTPase ModA, putative.	0.479
AFUA_5G05900	AFUA_2G03640	Q4WTS2	Q4WHZ6	Non-specific serine/threonine protein kinase.	Ras GTPase activating protein, putative.	0.514
AFUA_5G05900	AFUA_2G05740	Q4WTS2	Q4WHE0	Non-specific serine/threonine protein kinase.	Rho GTPase ModA, putative.	0.989
AFUA_5G05900	hulA	Q4WTS2	Q4WTF3	Non-specific serine/threonine protein kinase.	Probable E3 ubiquitin-protein ligase hulA; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Probably involved in the regulatory network controlling carbon source utilization.	0.480
AFUA_5G05900	ste20	Q4WTS2	Q4WHP3	Non-specific serine/threonine protein kinase.	Serine/threonine-protein kinase ste20; MAP4K component of the MAPK pathway required for the mating pheromone response and the regulation of cell polarity and cell cycle. Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.	0.818
hulA	AFUA_2G03640	Q4WTF3	Q4WHZ6	Probable E3 ubiquitin-protein ligase hulA; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Probably involved in the regulatory network controlling carbon source utilization.	Ras GTPase activating protein, putative.	0.592
hulA	AFUA_2G05740	Q4WTF3	Q4WHE0	Probable E3 ubiquitin-protein ligase hulA; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Probably involved in the regulatory network controlling carbon source utilization.	Rho GTPase ModA, putative.	0.587
hulA	AFUA_5G05900	Q4WTF3	Q4WTS2	Probable E3 ubiquitin-protein ligase hulA; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Probably involved in the regulatory network controlling carbon source utilization.	Non-specific serine/threonine protein kinase.	0.480
hulA	ste20	Q4WTF3	Q4WHP3	Probable E3 ubiquitin-protein ligase hulA; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Probably involved in the regulatory network controlling carbon source utilization.	Serine/threonine-protein kinase ste20; MAP4K component of the MAPK pathway required for the mating pheromone response and the regulation of cell polarity and cell cycle. Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.	0.480