STRINGSTRING
AFUA_4G07700 AFUA_4G07700 AFUA_5G08300 AFUA_5G08300 AFUA_5G05900 AFUA_5G05900 AFUA_5G05860 AFUA_5G05860 hulA hulA AFUA_4G09090 AFUA_4G09090 AFUA_6G07490 AFUA_6G07490 AFUA_6G07560 AFUA_6G07560 AFUA_2G03640 AFUA_2G03640 hse1 hse1 ste20 ste20 vps27 vps27 AFUA_2G05740 AFUA_2G05740
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AFUA_4G07700Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1693 aa)
AFUA_5G08300Alpha-actinin, sarcomeric (F-actin cross linking protein). (645 aa)
AFUA_5G05900Non-specific serine/threonine protein kinase. (836 aa)
AFUA_5G05860CRIB domain-containing protein. (815 aa)
hulAProbable E3 ubiquitin-protein ligase hulA; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Probably involved in the regulatory network controlling carbon source utilization. (813 aa)
AFUA_4G09090Thioredoxin, putative. (333 aa)
AFUA_6G07490WD repeat protein. (1160 aa)
AFUA_6G07560Transcription factor Rap1, putative. (315 aa)
AFUA_2G03640Ras GTPase activating protein, putative. (1750 aa)
hse1Class E vacuolar protein-sorting machinery protein hse1; Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB). (584 aa)
ste20Serine/threonine-protein kinase ste20; MAP4K component of the MAPK pathway required for the mating pheromone response and the regulation of cell polarity and cell cycle. Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. (815 aa)
vps27Vacuolar protein sorting-associated protein 27; Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane. (729 aa)
AFUA_2G05740Rho GTPase ModA, putative. (192 aa)
Your Current Organism:
Aspergillus fumigatus
NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.