STRINGSTRING
AFUA_4G04612 AFUA_4G04612 AFUA_6G05050 AFUA_6G05050 AFUA_2G04710 AFUA_2G04710 AFUA_1G04890 AFUA_1G04890 get1 get1 AFUA_4G06950 AFUA_4G06950 AFUA_4G13500 AFUA_4G13500 AFUA_1G09830 AFUA_1G09830 AFUA_3G06901 AFUA_3G06901 AFUA_3G07590 AFUA_3G07590 get3 get3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AFUA_4G04612Ubiquitin-conjugating enzyme Ubc6, putative. (307 aa)
AFUA_6G05050DUF410 domain protein. (346 aa)
AFUA_2G04710Cytochrome b5, putative; Belongs to the cytochrome b5 family. (217 aa)
AFUA_1G04890Translocon protein Sec61beta, putative. (131 aa)
get1Protein get1; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble get3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. (200 aa)
AFUA_4G06950Integral ER membrane protein Scs2, putative. (328 aa)
AFUA_4G13500Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (514 aa)
AFUA_1G09830Hsc70 cochaperone (SGT), putative. (341 aa)
AFUA_3G06901Protein translocation complex subunit Sss1, putative. (88 aa)
AFUA_3G07590ER-Golgi SNARE complex subunit (Sed5), putative. (346 aa)
get3ATPase get3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...] (340 aa)
Your Current Organism:
Aspergillus fumigatus
NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293
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