106 items (Aspergillus fumigatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AFUA_3G06200	Anaphase-promoting complex subunit Apc5, putative. (768 aa)
	AFUA_3G07970	Uncharacterized protein. (428 aa)
	AFUA_1G06762	Leucine Rich Repeat domain protein. (920 aa)
	AFUA_1G07625	WD domain protein. (423 aa)
	AFUA_1G11410	Ubiquitin conjugating enzyme E2, putative; Belongs to the ubiquitin-conjugating enzyme family. (427 aa)
	AFUA_1G12960	SCF ubiquitin ligase complex subunit CulA, putative; Belongs to the cullin family. (769 aa)
	AFUA_4G01242	Uncharacterized protein. (366 aa)
	AFUA_4G01500	Lignostilbene dioxygenase, putative. (498 aa)
	AFUA_7G01380	Anaphase promoting complex subunit Apc11, putative. (105 aa)
	AFUA_7G01390	Uncharacterized protein. (383 aa)
	AFUA_8G01100	Melibiase subfamily, putative. (783 aa)
	AFUA_8G01130	Alpha-galactosidase; Hydrolyzes a variety of simple alpha-D-galactoside as well as more complex molecules such as oligosaccharides and polysaccharides. Belongs to the glycosyl hydrolase. (728 aa)
	AFUA_8G04390	Uncharacterized protein. (291 aa)
	AFUA_6G04230	RBR-type E3 ubiquitin transferase. (620 aa)
	AFUA_5G02440	20S cyclosome subunit (APC8), putative. (689 aa)
	AFUA_5G02590	20S cyclosome subunit (Cut9/Cdc16), putative. (621 aa)
	AFUA_5G04330	Aminopeptidase. (967 aa)
	AFUA_3G02175	BTB/POZ domain protein. (281 aa)
	AFUA_7G03830	DNA repair protein Rad7, protein. (642 aa)
	AFUA_7G05930	Metallopeptidase MepB. (716 aa)
	AFUA_7G06820	Galactose oxidase, putative. (715 aa)
	AFUA_7G07100	Pfs, NACHT and WD domain protein. (1454 aa)
	AFUA_7G08640	BTB/POZ domain protein. (258 aa)
	AFUA_2G06220	Zinc knuckle domain protein. (632 aa)
	jhd1	JmjC domain-containing histone demethylation protein 1; Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code. (1418 aa)
	AFUA_2G05210	Anaphase-promoting complex subunit ApcB, putative; Belongs to the cullin family. (894 aa)
	AFUA_2G04450	HECT domain protein. (1337 aa)
	AFUA_2G04190	Uncharacterized protein. (705 aa)
	AFUA_2G03370	Uncharacterized protein. (576 aa)
	AFUA_2G03170	Cyclic nucleotide-binding domain protein. (900 aa)
	AFUA_2G02860	F-box domain protein. (727 aa)
	AFUA_2G02570	F-box domain protein. (378 aa)
	AFUA_2G00850	Uncharacterized protein. (220 aa)
	plyA	Probable pectate lyase A; Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins. Favors pectate, the anion, over pectin, the methyl ester (By similarity); Belongs to the polysaccharide lyase 1 family. (321 aa)
	AFUA_1G06540	C6 transcription factor, putative. (699 aa)
	AFUA_1G05970	Ubiquitin ligase complex F-box protein GRR1, putative. (586 aa)
	AFUA_1G04640	Ubiquitin-protein ligase (Hul4), putative. (1201 aa)
	AFUA_1G04510	BTB domain-containing protein. (295 aa)
	AFUA_1G04210	IQ and HECT domain protein. (1225 aa)
	AFUA_1G02280	Uncharacterized protein. (704 aa)
	AFUA_1G01990	Ribosome biogenesis protein Rsa4, putative. (515 aa)
	AFUA_1G00790	Uncharacterized protein. (1416 aa)
	AFUA_6G14130	Ubiquitin conjugating enzyme, putative; Belongs to the ubiquitin-conjugating enzyme family. (168 aa)
	AFUA_6G14120	Uncharacterized protein. (373 aa)
	AFUA_6G13030	Cell division control protein Cdc4, putative. (1079 aa)
	nudF	Nuclear distribution protein nudF; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family. (467 aa)
	AFUA_6G12540	RBR-type E3 ubiquitin transferase. (532 aa)
	AFUA_6G12310	Ubiquinone biosynthesis protein; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. (299 aa)
	AFUA_6G09160	Ubiquitin conjugating enzyme Ubc8, putative; Belongs to the ubiquitin-conjugating enzyme family. (202 aa)
	AFUA_6G08880	Ubiquitin-protein ligase Ufd4, putative. (1817 aa)
	AFUA_6G08420	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (2150 aa)
	AFUA_6G07590	RING-type domain-containing protein. (240 aa)
	AFUA_4G06170	BZIP domain-containing protein. (289 aa)
	AFUA_4G07260	Cell morphogenesis protein Sog2, putative. (972 aa)
	AFUA_4G07340	Ubiquitin fusion degradation protein UfdB, putative. (1088 aa)
	ytm1	Ribosome biogenesis protein ytm1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (488 aa)
	AFUA_4G08840	RING finger protein, putative. (232 aa)
	AFUA_4G09030	Aminopeptidase. (953 aa)
	AFUA_4G10570	Cell cycle regulatory protein, putative. (877 aa)
	AFUA_4G10780	Ubiquitin-protein ligase (Tom1), putative. (4037 aa)
	AFUA_4G11440	F-box and WD domain protein. (879 aa)
	AFUA_4G11700	Leucine Rich Repeat domain protein. (647 aa)
	AFUA_4G13940	Ubiquitin conjugating enzyme, putative. (1158 aa)
	AFUA_4G14620	RING finger protein. (134 aa)
	AFUA_1G17280	Uncharacterized protein. (394 aa)
	AFUA_1G16070	Uncharacterized protein. (1079 aa)
	AFUA_1G15770	Anaphase promoting complex subunit 10 (APC10), putative. (454 aa)
	AFUA_1G15710	Anaphase-promoting complex component Cut20/Apc4, putative. (735 aa)
	AFUA_1G15570	Ubiquitin-conjugating enzyme, putative. (287 aa)
	AFUA_1G14730	Cell division cycle protein Cdc20, putative. (619 aa)
	AFUA_1G13920	RING zinc finger protein, putative. (1643 aa)
	hulA	Probable E3 ubiquitin-protein ligase hulA; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Probably involved in the regulatory network controlling carbon source utilization. (813 aa)
	AFUA_1G08900	CHY and RING finger domain protein, putative. (740 aa)
	AFUA_5G05790	Ubiquitin ligase subunit HrtA, putative. (120 aa)
	sconC	E3 ubiquitin ligase complex SCF subunit sconC; Essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Controls sulfur metabolite repression, probably by mediating the inactivation or degradation of the metR transcription factor (By similarity). (158 aa)
	AFUA_5G06370	WHIM1 domain-containing protein. (580 aa)
	AFUA_5G07040	Ubiquitin conjugating enzyme (UbcA), putative; Belongs to the ubiquitin-conjugating enzyme family. (272 aa)
	AFUA_5G08230	C3HC4 finger protein. (473 aa)
	AFUA_5G08370	Polyubiquitin binding protein (Doa1/Ufd3), putative. (790 aa)
	AFUA_5G09080	Transcription factor (SPT8), putative. (612 aa)
	AFUA_5G09200	Ubiquitin conjugating enzyme (UbcC), putative; Belongs to the ubiquitin-conjugating enzyme family. (229 aa)
	mdv1	Mitochondrial division protein 1; Involved in mitochondrial fission. Acts as an adapter protein required to form mitochondrial fission complexes. Formation of these complexes is required to promote constriction and fission of the mitochondrial compartment at a late step in mitochondrial division (By similarity); Belongs to the WD repeat MDV1/CAF4 family. (658 aa)
	AFUA_5G13500	RING finger domain protein, putative. (330 aa)
	AFUA_5G14980	Uncharacterized protein. (1080 aa)
	AFUA_3G05570	Spindle poison sensitivity protein Scp3, putative. (638 aa)
	AFUA_3G05950	20S cyclosome subunit (APC1/BimE), putative. (2080 aa)
	AFUA_2G14580	Manganese ion homeostasis (Fr), putative. (673 aa)
	AFUA_3G08280	Cell cycle regulatory protein (Srw1), putative. (603 aa)
	AFUA_3G11260	Ubiquitin (UbiC), putative. (154 aa)
	AFUA_3G11870	F-box and WD40 domain protein, putative. (680 aa)
	AFUA_3G12190	RING finger domain protein, putative. (156 aa)
	AFUA_3G13060	Ubiquitin conjugating enzyme, putative. (1062 aa)
	AFUA_3G13080	BTB domain-containing protein. (259 aa)
	AFUA_3G13590	Uncharacterized protein. (542 aa)
	AFUA_2G16470	Ubiquitin conjugating enzyme (UbcF), putative. (312 aa)
	AFUA_2G15040	Ubiquitin conjugating enzyme, putative. (467 aa)
	AFUA_2G08620	20S cyclosome subunit (BimA/Nuc2/Cdc27), putative. (809 aa)
	AFUA_2G09240	F-box protein (Pof7), putative. (550 aa)
	AFUA_2G10470	ATP-dependent protease (CrgA), putative. (626 aa)
	AFUA_2G10700	Alpha-tubulin suppressor protein Aats1, putative. (377 aa)
	AFUA_2G10760	Lysophospholipase A, putative. (342 aa)
	AFUA_2G11040	U-box domain protein, putative. (284 aa)
	AFUA_2G12060	F-box and WD repeat-containing protein. (651 aa)
	AFUA_2G13310	RING finger domain protein, putative. (444 aa)
	AFUA_2G13690	Ubiquitin conjugating enzyme, putative. (157 aa)
	AFUA_2G14260	Uncharacterized protein. (959 aa)

Your Current Organism:

Aspergillus fumigatus

NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFUA_1G00790	AFUA_1G12960	Q4WKY9	E9R1Z4	Uncharacterized protein.	SCF ubiquitin ligase complex subunit CulA, putative; Belongs to the cullin family.	0.451
AFUA_1G00790	AFUA_5G05790	Q4WKY9	Q4WTR1	Uncharacterized protein.	Ubiquitin ligase subunit HrtA, putative.	0.453
AFUA_1G01990	ytm1	Q4WKM1	Q4WP10	Ribosome biogenesis protein Rsa4, putative.	Ribosome biogenesis protein ytm1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	0.806
AFUA_1G02280	AFUA_1G12960	Q4WKJ2	E9R1Z4	Uncharacterized protein.	SCF ubiquitin ligase complex subunit CulA, putative; Belongs to the cullin family.	0.498
AFUA_1G02280	AFUA_5G05790	Q4WKJ2	Q4WTR1	Uncharacterized protein.	Ubiquitin ligase subunit HrtA, putative.	0.463
AFUA_1G02280	AFUA_8G04390	Q4WKJ2	Q4WCH6	Uncharacterized protein.	Uncharacterized protein.	0.527
AFUA_1G02280	sconC	Q4WKJ2	Q4WTT8	Uncharacterized protein.	E3 ubiquitin ligase complex SCF subunit sconC; Essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Controls sulfur metabolite repression, probably by mediating the inactivation or degradation of the metR transcription factor (By similarity).	0.527
AFUA_1G04210	AFUA_1G13920	Q4WK02	Q4WS58	IQ and HECT domain protein.	RING zinc finger protein, putative.	0.477
AFUA_1G04210	AFUA_4G07340	Q4WK02	Q4WNY0	IQ and HECT domain protein.	Ubiquitin fusion degradation protein UfdB, putative.	0.453
AFUA_1G04210	AFUA_6G08880	Q4WK02	Q4WMS5	IQ and HECT domain protein.	Ubiquitin-protein ligase Ufd4, putative.	0.548
AFUA_1G04510	AFUA_1G12960	Q4WJX1	E9R1Z4	BTB domain-containing protein.	SCF ubiquitin ligase complex subunit CulA, putative; Belongs to the cullin family.	0.451
AFUA_1G04510	AFUA_5G05790	Q4WJX1	Q4WTR1	BTB domain-containing protein.	Ubiquitin ligase subunit HrtA, putative.	0.453
AFUA_1G05970	AFUA_1G12960	Q4WJH3	E9R1Z4	Ubiquitin ligase complex F-box protein GRR1, putative.	SCF ubiquitin ligase complex subunit CulA, putative; Belongs to the cullin family.	0.919
AFUA_1G05970	AFUA_3G11260	Q4WJH3	Q4WXZ8	Ubiquitin ligase complex F-box protein GRR1, putative.	Ubiquitin (UbiC), putative.	0.416
AFUA_1G05970	AFUA_4G06170	Q4WJH3	Q4WNL5	Ubiquitin ligase complex F-box protein GRR1, putative.	BZIP domain-containing protein.	0.416
AFUA_1G05970	AFUA_5G05790	Q4WJH3	Q4WTR1	Ubiquitin ligase complex F-box protein GRR1, putative.	Ubiquitin ligase subunit HrtA, putative.	0.864
AFUA_1G05970	AFUA_6G13030	Q4WJH3	Q4WLM1	Ubiquitin ligase complex F-box protein GRR1, putative.	Cell division control protein Cdc4, putative.	0.480
AFUA_1G05970	AFUA_8G04390	Q4WJH3	Q4WCH6	Ubiquitin ligase complex F-box protein GRR1, putative.	Uncharacterized protein.	0.909
AFUA_1G05970	sconC	Q4WJH3	Q4WTT8	Ubiquitin ligase complex F-box protein GRR1, putative.	E3 ubiquitin ligase complex SCF subunit sconC; Essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Controls sulfur metabolite repression, probably by mediating the inactivation or degradation of the metR transcription factor (By similarity).	0.986
AFUA_1G06540	AFUA_1G12960	Q4WJB7	E9R1Z4	C6 transcription factor, putative.	SCF ubiquitin ligase complex subunit CulA, putative; Belongs to the cullin family.	0.498