STRINGSTRING
AFUA_6G05040 AFUA_6G05040 AFUA_5G01870 AFUA_5G01870 AFUA_5G02520 AFUA_5G02520 AFUA_2G06320 AFUA_2G06320 AFUA_2G06190 AFUA_2G06190 AFUA_2G05570 AFUA_2G05570 AFUA_1G07600 AFUA_1G07600 AFUA_1G07180 AFUA_1G07180 AFUA_1G04900 AFUA_1G04900 AFUA_1G03920 AFUA_1G03920 AFUA_1G03410 AFUA_1G03410 AFUA_6G11130 AFUA_6G11130 AFUA_6G10560 AFUA_6G10560 AFUA_4G07970 AFUA_4G07970 AFUA_4G12210 AFUA_4G12210 AFUA_1G10020 AFUA_1G10020 AFUA_5G10890 AFUA_5G10890 AFUA_5G13020 AFUA_5G13020 AFUA_5G14820 AFUA_5G14820 fen1 fen1 AFUA_3G08300 AFUA_3G08300 AFUA_3G09020 AFUA_3G09020 pol2 pol2 AFUA_3G11140 AFUA_3G11140 AFUA_3G14010 AFUA_3G14010 AFUA_2G16710 AFUA_2G16710 AFUA_2G16600 AFUA_2G16600 AFUA_2G12250 AFUA_2G12250 AFUA_2G12220 AFUA_2G12220 AFUA_2G10730 AFUA_2G10730 MCM7 MCM7 AFUA_2G09060 AFUA_2G09060 AFUA_2G09010 AFUA_2G09010
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AFUA_6G05040DNA replication factor C subunit Rfc4, putative. (348 aa)
AFUA_5G01870DNA replication factor C subunit Rfc3, putative. (396 aa)
AFUA_5G02520DNA helicase; Belongs to the MCM family. (718 aa)
AFUA_2G06320Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (529 aa)
AFUA_2G06190DNA polymerase epsilon subunit B, putative. (762 aa)
AFUA_2G05570Uncharacterized protein. (169 aa)
AFUA_1G07600Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (363 aa)
AFUA_1G07180Ribonuclease H, putative. (410 aa)
AFUA_1G04900Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (219 aa)
AFUA_1G03920DNA helicase; Belongs to the MCM family. (892 aa)
AFUA_1G03410DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (500 aa)
AFUA_6G11130Possible replication factor-a protein. (289 aa)
AFUA_6G10560DNA polymerase delta subunit 4, putative. (193 aa)
AFUA_4G07970DNA polymerase delta subunit 2, putative. (554 aa)
AFUA_4G12210DNA replication helicase Dna2, putative. (1657 aa)
AFUA_1G10020Ribonuclease H1, putative. (221 aa)
AFUA_5G10890DNA helicase; Belongs to the MCM family. (956 aa)
AFUA_5G13020DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (617 aa)
AFUA_5G14820Replication factor C subunit. (389 aa)
fen1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (395 aa)
AFUA_3G08300DNA replication factor C subunit Rfc2, putative. (394 aa)
AFUA_3G09020DNA primase; Belongs to the eukaryotic-type primase small subunit family. (522 aa)
pol2DNA polymerase epsilon catalytic subunit A; DNA polymerase II participates in chromosomal DNA replication. (2230 aa)
AFUA_3G11140DNA ligase. (833 aa)
AFUA_3G14010DNA helicase; Belongs to the MCM family. (896 aa)
AFUA_2G16710Uncharacterized protein. (438 aa)
AFUA_2G16600DNA polymerase. (1105 aa)
AFUA_2G12250DNA replication factor C subunit Rfc5, putative. (294 aa)
AFUA_2G12220Replication factor C subunit 1. (1085 aa)
AFUA_2G10730DNA polymerase. (1462 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (854 aa)
AFUA_2G09060DNA helicase; Belongs to the MCM family. (1023 aa)
AFUA_2G09010DNA ligase. (909 aa)
Your Current Organism:
Aspergillus fumigatus
NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293
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